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Polfa Tarchomin is a leading Polish pharmaceutical company with 200 year tradition in manufacture and sale of pharmaceutical products.

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ACTIVE PHARMA INGREDIENTS

25 API Suppliers, 6 USDMF, 3 CEP/COS, 1 JDMF, 20 Listed Suppliers, $ API Reference Price

25 API Suppliers
6 USDMF
3 CEP/COS
1 JDMF
20 Listed Suppliers
$ API Reference Price

DEVELOPMENTS

3 Drugs in Development

3 Drugs in Development

FINISHED DOSAGE FORMULATIONS

34 FDF Dossiers, 8 FDA Orange Book, 2 Europe, 4 Canada, 2 Australia, 4 South Africa, 14 Listed Dossiers

34 FDF Dossiers
8 FDA Orange Book
2 Europe
4 Canada
2 Australia
4 South Africa
14 Listed Dossiers

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EXCIPIENTS BY APPLICATIONS

89 Fillers, Diluents & Binders, 60 Coating Systems & Additives, 45 Direct Compression, 42 Disintegrants & Superdisintegrants, 41 Thickeners and Stabilizers, 38 Solubilizers, 35 Controlled & Modified Release, 32 Taste Masking, 30 Granulation, 27 Parenteral, 25 Film Formers & Plasticizers, 23 Topical, 21 Lubricants & Glidants, 21 Co-Processed Excipients, 20 Chewable & Orodispersible Aids, 14 Emulsifying Agents, 9 Empty Capsules, 9 API Stability Enhancers, 7 Rheology Modifiers, 4 Vegetarian Capsules, 4 Surfactant & Foaming Agents, 4 Coloring Agents, 1 Soft Gelatin

DIGITAL CONTENT

1 DATA COMPILATION #PharmaFlow, 13 NEWS #PharmaBuzz

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1 DATA COMPILATION #PharmaFlow
13 NEWS #PharmaBuzz

MARKET PLACE

13 APIs, 2 FDF Dossiers

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13 APIs
2 FDF Dossiers

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1 EDQM

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1 EDQM

Synopsis

ACTIVE PHARMA INGREDIENTS

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API REF. PRICE (USD/KG)

$ 2

MARKET PLACE

API

FDF

0INTERMEDIATES

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FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

3DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

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Chemistry

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Also known as: Iron(ii) fumarate, 141-01-5, Feostat, Palafer, Galfer, Ircon

Molecular Formula

C₄H₂FeO₄

Molecular Weight

169.90 g/mol

InChI Key

PMVSDNDAUGGCCE-TYYBGVCCSA-L

FDA UNII

R5L488RY0Q

Ferrous Fumarate is the fumarate salt form of the mineral iron. Administration of ferrous fumarate results in elevation of serum iron concentration, which is then assimilated into hemoglobin, required for the transport of oxygen, or trapped in the reticuloendothelial cells for storage. This agent is used as a dietary supplement, and to prevent or treat iron deficiency related syndromes.

1 2D Structure

Ferrous Fumarate

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(E)-but-2-enedioate;iron(2+)

2.1.2 InChI

InChI=1S/C4H4O4.Fe/c5-3(6)1-2-4(7)8;/h1-2H,(H,5,6)(H,7,8);/q;+2/p-2/b2-1+;

2.1.3 InChI Key

PMVSDNDAUGGCCE-TYYBGVCCSA-L

2.1.4 Canonical SMILES

C(=CC(=O)[O-])C(=O)[O-].[Fe+2]

2.1.5 Isomeric SMILES

C(=C/C(=O)[O-])\C(=O)[O-].[Fe+2]

2.2 Other Identifiers

2.2.1 UNII

R5L488RY0Q

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Feostat

2. Ferrocap

3. Fersaday

4. Fersamal

5. Ferval

6. Fumar

7. Galfer

8. Ircon

9. Nephro-fer

10. Palafer

11. Rulofer N

2.3.2 Depositor-Supplied Synonyms

1. Iron(ii) Fumarate

2. 141-01-5

3. Feostat

4. Palafer

5. Galfer

6. Ircon

7. Ercoferro

8. Ferrofume

9. Tolferain

10. Cpiron

11. Hemoton

12. Toleron

13. Tolifer

14. Erco-fer

15. Ferrousfumarate

16. Iron(2+) Fumarate

17. Iron Fumarate

18. 2-butenedioic Acid (2e)-, Iron(2+) Salt (1:1)

19. Fumaric Acid, Iron(2+) Salt (1:1)

20. 2-butenedioic Acid (e)-, Iron(2+) Salt (1:1)

21. R5l488ry0q

22. 2-butenedioic Acid, (e)-, Iron(2+) Salt

23. Fersamal

24. Fumar

25. (e)-but-2-enedioate;iron(2+)

26. Feroton

27. Ferronat

28. Ferrone

29. Ferrotemp

30. Fumafer

31. Fumiron

32. Firon

33. One-iron

34. Fumar-f

35. Ferrocite

36. Fumaric Acid, Iron(2+) Salt

37. Ccris 6896

38. Einecs 205-447-7

39. Unii-r5l488ry0q

40. Ferrofumarate

41. Heferol

42. Orgasal

43. Ferrous Fumarate [usp:jan]

44. Feostat (tn)

45. Ferrum (tn)

46. Iron (as Fumarate)

47. Meterfer

48. Iron (as Ferrous Fumarate)

49. Schembl24284

50. Schembl24286

51. Ferrous Fumarate (jan/usp)

52. Ferrous Fumarate [ii]

53. Ferrous Fumarate [mi]

54. Ferrous Fumarate [fcc]

55. Ferrous Fumarate [jan]

56. Ferrous Fumarate [inci]

57. Dtxsid7047148

58. Ferrous Fumarate [vandf]

59. Chebi:31607

60. Amy8976

61. Ferrous Fumarate [mart.]

62. Ferrous Fumarate [who-dd]

63. Ferrous Fumarate [who-ip]

64. Hy-b1651

65. Einecs 231-731-5

66. Mfcd00058315

67. Akos015918237

68. Ferrous Fumarate [orange Book]

69. Db14491

70. Ferrosi Fumaras [who-ip Latin]

71. Ferrous Fumarate [ep Monograph]

72. Ferrous Fumarate [usp Monograph]

73. Iron (as Ferrous Fumarate) [vandf]

74. 2-butenedioic Acid (2e)-, Iron(2+) Salt

75. Cs-0013603

76. Norquest Fe Component Ferrous Fumarate

77. D01194

78. Ferrous Fumarate Component Of Norquest Fe

79. Lo Minastrin Fe Component Ferrous Fumarate

80. Minastrin 24 Fe Component Ferrous Fumarate

81. Q416370

82. 2-butenedioic Acid (2e)-, Iron(2+) Salt (1:?)

83. J-007445

84. J-521364

85. 7705-12-6

2.4 Create Date

2006-04-28

3 Chemical and Physical Properties

Molecular Formula	C₄H₂FeO₄
Molecular Weight	169.90 g/mol
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	0
Exact Mass	169.930244 g/mol
Monoisotopic Mass	169.930244 g/mol
Topological Polar Surface Area	80.3 Å²
Heavy Atom Count	9
Formal Charge	0
Complexity	108
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Drug and Medication Information

4.1 Drug Information

1 of 2
Drug Name	Ferrous fumarate
Active Ingredient	Ferrous fumarate
Dosage Form	Tablet
Route	oral
Strength	75mg
Market Status	Tentative Approval
Company	Barr Labs

2 of 2
Drug Name	Ferrous fumarate
Active Ingredient	Ferrous fumarate
Dosage Form	Tablet
Route	oral
Strength	75mg
Market Status	Tentative Approval
Company	Barr Labs

4.2 Drug Indication

Used in preventing and treating iron-deficiency anemia.

5 Pharmacology and Biochemistry

5.1 Pharmacology

The major activity of supplemental iron is in the prevention and treatment of iron deficiency anemia. Iron has putative immune-enhancing, anticarcinogenic and cognition-enhancing activities.

5.2 MeSH Pharmacological Classification

Trace Elements

A group of chemical elements that are needed in minute quantities for the proper growth, development, and physiology of an organism. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) (See all compounds classified as Trace Elements.)

5.3 ATC Code

B - Blood and blood forming organs

B03 - Antianemic preparations

B03A - Iron preparations

B03AA - Iron bivalent, oral preparations

B03AA02 - Ferrous fumarate

B - Blood and blood forming organs

B03 - Antianemic preparations

B03A - Iron preparations

B03AD - Iron in combination with folic acid

B03AD02 - Ferrous fumarate

5.4 Absorption, Distribution and Excretion

Absorption

The efficiency of absorption depends on the salt form, the amount administered, the dosing regimen and the size of iron stores. Subjects with normal iron stores absorb 10% to 35% of an iron dose. Those who are iron deficient may absorb up to 95% of an iron dose.

5.5 Mechanism of Action

Iron is necessary for the production of hemoglobin. Iron-deficiency can lead to decreased production of hemoglobin and a microcytic, hypochromic anemia.

API SUPPLIERS

01

Jai Radhe Sales

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Pharma, Lab & Chemical Expo

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Jai Radhe Sales is your partner for all your sourcing needs.

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02

Pharm-RX Chemical

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Not Confirmed

Pharm-Rx is a reputed global importer and distributor of pharmaceutical active ingredients.

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U.S.A

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03

Octavius Pharma Pvt. Ltd

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

MAGHREB PHARMA

Stand #B09

Octavius has been empowering lives since 1980 by providing quality products like DC granules, APIs and FDFs.

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04

Salvi Chemical Industries

India

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Pharma, Lab & Chemical Expo

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08

F. Hoffmann-La Roche

Switzerland

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09

Polydrug Laboratories Private Limi...

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Pharma, Lab & Chemical Expo

Not Confirmed

10

Ferron Pharma

Indonesia

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CEP/COS

01

DR. PAUL LOHMANN GMBH & CO. KGAA Em...

Germany

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02

FERROPHARMA CHEMICALS LTD. Dóc HU

Indonesia

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03

POLYDRUG LABORATORIES PVT. LTD. Mum...

India

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API Reference Price

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PAUL LOHMANN GMBH KG","supplierCountry":"GERMANY","foreign_port":"HANNOVER","customer":"AUROBINDO PHARMA LIMITED","customerCountry":"INDIA","quantity":"800.00","actualQuantity":"800","unit":"KGS","unitRateFc":"16.2","totalValueFC":"13093.6","currency":"USD","unitRateINR":"1358","date":"14-Feb-2024","totalValueINR":"1086426","totalValueInUsd":"13093.6","indian_port":"SEZ\/Mahaboobnagar","hs_no":"29171990","bill_no":"1000481","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"HANNOVER","supplierAddress":"N\/A","customerAddress":"PLOT NO.2, MAITRIVIHAR,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1712514600,"product":"FERROUS FUMARATE","address":"FIRST FLOOR, ELEGANCE TOWER,","city":"COMMERCIAL CENTRE, JASOLA NEW DELHI","supplier":"ACCESS BUSINESS GROUP ","supplierCountry":"UNITED STATES","foreign_port":"LOS ANGELES","customer":"AMWAY INDIA ENTERPRISES PVT LTD","customerCountry":"INDIA","quantity":"399.04","actualQuantity":"399.04","unit":"KGS","unitRateFc":"1640.4","totalValueFC":"8160.6","currency":"INR","unitRateINR":"1707.8","date":"08-Apr-2024","totalValueINR":"681472.4","totalValueInUsd":"8160.6","indian_port":"JNPT","hs_no":"29171940","bill_no":"2933549","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"LOS ANGELES","supplierAddress":"7575 FULTON STREET EAST ADA MI 49355 UNITED STATES Fulton, , UNITED STATES UNITED STATES","customerAddress":"FIRST FLOOR, ELEGANCE TOWER,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1716316200,"product":"FERROUS FUMARATE","address":"FIRST FLOOR, ELEGANCE TOWER,","city":"COMMERCIAL CENTRE, JASOLA NEW DELHI","supplier":"ACCESS BUSINESS GROUP ","supplierCountry":"UNITED STATES","foreign_port":"LOS ANGELES","customer":"AMWAY INDIA ENTERPRISES PVT LTD","customerCountry":"INDIA","quantity":"423.98","actualQuantity":"423.98","unit":"KGS","unitRateFc":"1640.4","totalValueFC":"8506.6","currency":"INR","unitRateINR":"1672.4","date":"22-May-2024","totalValueINR":"709061.65","totalValueInUsd":"8506.6","indian_port":"JNPT","hs_no":"29171940","bill_no":"3610691","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"LOS ANGELES","supplierAddress":"7575 FULTON STREET EAST ADA MI 49355 UNITED STATES Fulton, , UNITED STATES UNITED STATES","customerAddress":"FIRST FLOOR, ELEGANCE TOWER,"}]

Number of Transactions

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Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

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Importing Country	Total Quantity (KGS)	Average Price (USD/KGS)	Number of Transactions

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ABOUT THIS PAGE

Ferrous Fumarate Manufacturers

A Ferrous Fumarate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Ferrous Fumarate, including repackagers and relabelers. The FDA regulates Ferrous Fumarate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Ferrous Fumarate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Ferrous Fumarate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Ferrous Fumarate Suppliers

A Ferrous Fumarate supplier is an individual or a company that provides Ferrous Fumarate active pharmaceutical ingredient (API) or Ferrous Fumarate finished formulations upon request. The Ferrous Fumarate suppliers may include Ferrous Fumarate API manufacturers, exporters, distributors and traders.

click here to find a list of Ferrous Fumarate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Ferrous Fumarate USDMF

A Ferrous Fumarate DMF (Drug Master File) is a document detailing the whole manufacturing process of Ferrous Fumarate active pharmaceutical ingredient (API) in detail. Different forms of Ferrous Fumarate DMFs exist exist since differing nations have different regulations, such as Ferrous Fumarate USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Ferrous Fumarate DMF submitted to regulatory agencies in the US is known as a USDMF. Ferrous Fumarate USDMF includes data on Ferrous Fumarate's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Ferrous Fumarate USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Ferrous Fumarate suppliers with USDMF on PharmaCompass.

Ferrous Fumarate JDMF

The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

The Ferrous Fumarate Drug Master File in Japan (Ferrous Fumarate JDMF) empowers Ferrous Fumarate API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

PMDA reviews the Ferrous Fumarate JDMF during the approval evaluation for pharmaceutical products. At the time of Ferrous Fumarate JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

click here to find a list of Ferrous Fumarate suppliers with JDMF on PharmaCompass.

Ferrous Fumarate CEP

A Ferrous Fumarate CEP of the European Pharmacopoeia monograph is often referred to as a Ferrous Fumarate Certificate of Suitability (COS). The purpose of a Ferrous Fumarate CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Ferrous Fumarate EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Ferrous Fumarate to their clients by showing that a Ferrous Fumarate CEP has been issued for it. The manufacturer submits a Ferrous Fumarate CEP (COS) as part of the market authorization procedure, and it takes on the role of a Ferrous Fumarate CEP holder for the record. Additionally, the data presented in the Ferrous Fumarate CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Ferrous Fumarate DMF.

A Ferrous Fumarate CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Ferrous Fumarate CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

click here to find a list of Ferrous Fumarate suppliers with CEP (COS) on PharmaCompass.

Ferrous Fumarate GMP

Ferrous Fumarate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Ferrous Fumarate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Ferrous Fumarate GMP manufacturer or Ferrous Fumarate GMP API supplier for your needs.

Ferrous Fumarate CoA

A Ferrous Fumarate CoA (Certificate of Analysis) is a formal document that attests to Ferrous Fumarate's compliance with Ferrous Fumarate specifications and serves as a tool for batch-level quality control.

Ferrous Fumarate CoA mostly includes findings from lab analyses of a specific batch. For each Ferrous Fumarate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Ferrous Fumarate may be tested according to a variety of international standards, such as European Pharmacopoeia (Ferrous Fumarate EP), Ferrous Fumarate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Ferrous Fumarate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.

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