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Ferrous Succinate

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Chemistry

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Also known as: Iron succinate, 10030-90-7, Iron(ii) succinate, Butanedioate;iron(2+), Butanedioic acid, iron(2+) salt (1:1), 818zyk7n91

Molecular Formula

C₄H₄FeO₄

Molecular Weight

171.92 g/mol

InChI Key

MDXRFOWKIZPNTA-UHFFFAOYSA-L

FDA UNII

818ZYK7N91

1 2D Structure

Ferrous Succinate

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

butanedioate;iron(2+)

2.1.2 InChI

InChI=1S/C4H6O4.Fe/c5-3(6)1-2-4(7)8;/h1-2H2,(H,5,6)(H,7,8);/q;+2/p-2

2.1.3 InChI Key

MDXRFOWKIZPNTA-UHFFFAOYSA-L

2.1.4 Canonical SMILES

C(CC(=O)[O-])C(=O)[O-].[Fe+2]

2.2 Other Identifiers

2.2.1 UNII

818ZYK7N91

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Butanedioic Acid, Iron (+2) Salt

2. Ferromyn

3. Ferrosuccinate

2.3.2 Depositor-Supplied Synonyms

1. Iron Succinate

2. 10030-90-7

3. Iron(ii) Succinate

4. Butanedioate;iron(2+)

5. Butanedioic Acid, Iron(2+) Salt (1:1)

6. 818zyk7n91

7. Succinic Acid Iron(ii) Salt;succinic Acid Iron(ii) Salt

8. Unii-818zyk7n91

9. Ferrlecit 2

10. Einecs 233-082-3

11. Ferplex (tn)

12. Ferromyn

13. Succinic Acid Iron(ii) Salt

14. Schembl275423

15. Ferrous Succinate [mi]

16. Iron Succinate (fe(o4c4h4))

17. Ferrous Succinate [mart.]

18. Ferrous Succinate [who-dd]

19. Db14489

20. D08015

21. Succinic Acid, Iron(2+) Salt (1:1)

22. Q27269230

2.4 Create Date

2006-10-25

3 Chemical and Physical Properties

Molecular Formula	C₄H₄FeO₄
Molecular Weight	171.92 g/mol
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	1
Exact Mass	171.945894 g/mol
Monoisotopic Mass	171.945894 g/mol
Topological Polar Surface Area	80.3 Å²
Heavy Atom Count	9
Formal Charge	0
Complexity	81.6
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Drug and Medication Information

4.1 Drug Indication

Used in preventing and treating iron-deficiency anemia.

5 Pharmacology and Biochemistry

5.1 Pharmacology

The major activity of supplemental iron is in the prevention and treatment of iron deficiency anemia. Iron has putative immune-enhancing, anticarcinogenic and cognition-enhancing activities.

5.2 MeSH Pharmacological Classification

Hematinics

Agents which improve the quality of the blood, increasing the hemoglobin level and the number of erythrocytes. They are used in the treatment of anemias. (See all compounds classified as Hematinics.)

5.3 ATC Code

B - Blood and blood forming organs

B03 - Antianemic preparations

B03A - Iron preparations

B03AA - Iron bivalent, oral preparations

B03AA06 - Ferrous succinate

5.4 Absorption, Distribution and Excretion

Absorption

The efficiency of absorption depends on the salt form, the amount administered, the dosing regimen and the size of iron stores. Subjects with normal iron stores absorb 10% to 35% of an iron dose. Those who are iron deficient may absorb up to 95% of an iron dose.

5.5 Mechanism of Action

Iron is necessary for the production of hemoglobin. Iron-deficiency can lead to decreased production of hemoglobin and a microcytic, hypochromic anemia.

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