Find Fialuridine manufacturers, exporters & distributors on PharmaCompass

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Chemistry

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Also known as: 69123-98-4, Fiau, Fluoroiodoarauridine, 1-(2-deoxy-2-fluoro-b-d-arabinofuranosyl)-5-iodouracil, 53t7in77lc, 1-(2'fluoro-2'-deoxyarabinofuranosyl)-5-iodouracil
Molecular Formula
C9H10FIN2O5
Molecular Weight
372.09  g/mol
InChI Key
IPVFGAYTKQKGBM-BYPJNBLXSA-N
FDA UNII
53T7IN77LC

Fialuridine
Fialuridine is a nucleoside analog of uridine with activity against hepatitis B virus and herpes viruses. Fialuridine inhibits viral DNA polymerase and viral replication.
1 2D Structure

Fialuridine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione
2.1.2 InChI
InChI=1S/C9H10FIN2O5/c10-5-6(15)4(2-14)18-8(5)13-1-3(11)7(16)12-9(13)17/h1,4-6,8,14-15H,2H2,(H,12,16,17)/t4-,5+,6-,8-/m1/s1
2.1.3 InChI Key
IPVFGAYTKQKGBM-BYPJNBLXSA-N
2.1.4 Canonical SMILES
C1=C(C(=O)NC(=O)N1C2C(C(C(O2)CO)O)F)I
2.1.5 Isomeric SMILES
C1=C(C(=O)NC(=O)N1[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)F)I
2.2 Other Identifiers
2.2.1 UNII
53T7IN77LC
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 1-(2'fluoro-2'-deoxyarabinofuranosyl)-5-iodouracil

2. 1-(2-deoxy-2-fluoro-beta-d-arabinofuranosyl)-5-iodo-2,4(1h,3h)-pyrimidinedione

3. 1-(2-deoxy-2-fluoro-beta-d-arabinofuranosyl)-5-iodo-unracil

4. 123i-fiau

5. 2'-fluoro-5-iodoarauracil

6. Fiau

2.3.2 Depositor-Supplied Synonyms

1. 69123-98-4

2. Fiau

3. Fluoroiodoarauridine

4. 1-(2-deoxy-2-fluoro-b-d-arabinofuranosyl)-5-iodouracil

5. 53t7in77lc

6. 1-(2'fluoro-2'-deoxyarabinofuranosyl)-5-iodouracil

7. 1-[(2r,3s,4r,5r)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione

8. Nsc-678514

9. 1-((2r,3s,4r,5r)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodopyrimidine-2,4(1h,3h)-dione

10. Drg-0098

11. 1-(2-deoxy-2-fluoro-beta-d-arabinofuranosyl)-5-iodouracil

12. Fialuridine [usan:inn]

13. Unii-53t7in77lc

14. Mfcd00866922

15. 2'-fluoro-5-iodo-1-beta-d-arabinofuranosyluracil

16. Uracil, 1-(2-deoxy-2-fluoro-beta-d-arabinofuranosyl)-5-iodo-

17. Fialuridine [mi]

18. 2'-fluoro-5-iodouracil

19. Fialuridine [inn]

20. 5-iodo-2-fluoroarauracil

21. Fialuridine (usan/inn)

22. Fialuridine [usan]

23. Schembl3189

24. 1-(2-deoxy-2-fluoro-beta-d-arabinofuranosyl)-5-iodo-2,4(1h,3h)-pyrimidinedione

25. 2,4(1h,3h)-pyrimidinedione, 1-(2-deoxy-2-fluoro-beta-d-arabinofuranosyl)-5-iodo-

26. Fialuridine [mart.]

27. 1-(2-deoxy-2-fluoro-.beta.-d-arabinofuranosyl)-5-iodouracil

28. Chembl271475

29. Fialuridine, >=98% (hplc)

30. Dtxsid701028030

31. Zinc4216113

32. Bdbm50367488

33. Akos015856198

34. Akos016009483

35. Db15427

36. Nsc 678514

37. 1-[(2r,3s,4r,5r)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-iodo-pyrimidine-2,4-dione

38. Ac-32361

39. As-69583

40. Hy-118122

41. Cs-0065233

42. D04181

43. F12931

44. 691f984

45. A848801

46. J-700174

47. J-700352

48. Q5446286

49. 1-(2-deoxy-2-fluoro--d-arabinofuranosyl)-5-iodouracil

50. 1-(2'-deoxy-2'-fluoro-.beta.-d-arabinofuranosyl)-5-iodouracil

51. 1-(2'-deoxy-2'-fluoro-b-d-arabinofuranosyl)-5-iodouracil

52. 2,4(1h,3h)-pyrimidinedione, 1-(2-deoxy-2-fluoro-.beta.-d-arabinofuranosyl)-5-iodo-

53. 1-((2s,3r,4s,5s)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-5-iodopyrimidine-2,4(1h,3h)-dione

54. 1-[(2r,3s,4r,5r)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodo-1,2,3,4-tetrahydropyrimidine-2,4-dione

2.4 Create Date
2005-08-01
3 Chemical and Physical Properties
Molecular Weight 372.09 g/mol
Molecular Formula C9H10FIN2O5
XLogP3-0.9
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count6
Rotatable Bond Count2
Exact Mass371.96185 g/mol
Monoisotopic Mass371.96185 g/mol
Topological Polar Surface Area99.1 Ų
Heavy Atom Count18
Formal Charge0
Complexity418
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antiviral Agents

Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly. (See all compounds classified as Antiviral Agents.)


Nucleic Acid Synthesis Inhibitors

Compounds that inhibit cell production of DNA or RNA. (See all compounds classified as Nucleic Acid Synthesis Inhibitors.)


ABOUT THIS PAGE

Looking for 69123-98-4 / Fialuridine API manufacturers, exporters & distributors?

Fialuridine manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Fialuridine API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Fialuridine manufacturer or Fialuridine supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Fialuridine manufacturer or Fialuridine supplier.

PharmaCompass also assists you with knowing the Fialuridine API Price utilized in the formulation of products. Fialuridine API Price is not always fixed or binding as the Fialuridine Price is obtained through a variety of data sources. The Fialuridine Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Fialuridine

Synonyms

69123-98-4, Fiau, Fluoroiodoarauridine, 1-(2-deoxy-2-fluoro-b-d-arabinofuranosyl)-5-iodouracil, 53t7in77lc, 1-(2'fluoro-2'-deoxyarabinofuranosyl)-5-iodouracil

Cas Number

69123-98-4

Unique Ingredient Identifier (UNII)

53T7IN77LC

About Fialuridine

Fialuridine is a nucleoside analog of uridine with activity against hepatitis B virus and herpes viruses. Fialuridine inhibits viral DNA polymerase and viral replication.

Fialuridine Manufacturers

A Fialuridine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Fialuridine, including repackagers and relabelers. The FDA regulates Fialuridine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Fialuridine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Fialuridine Suppliers

A Fialuridine supplier is an individual or a company that provides Fialuridine active pharmaceutical ingredient (API) or Fialuridine finished formulations upon request. The Fialuridine suppliers may include Fialuridine API manufacturers, exporters, distributors and traders.

click here to find a list of Fialuridine suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Fialuridine USDMF

A Fialuridine DMF (Drug Master File) is a document detailing the whole manufacturing process of Fialuridine active pharmaceutical ingredient (API) in detail. Different forms of Fialuridine DMFs exist exist since differing nations have different regulations, such as Fialuridine USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Fialuridine DMF submitted to regulatory agencies in the US is known as a USDMF. Fialuridine USDMF includes data on Fialuridine's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Fialuridine USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Fialuridine suppliers with USDMF on PharmaCompass.

Fialuridine GMP

Fialuridine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Fialuridine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Fialuridine GMP manufacturer or Fialuridine GMP API supplier for your needs.

Fialuridine CoA

A Fialuridine CoA (Certificate of Analysis) is a formal document that attests to Fialuridine's compliance with Fialuridine specifications and serves as a tool for batch-level quality control.

Fialuridine CoA mostly includes findings from lab analyses of a specific batch. For each Fialuridine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Fialuridine may be tested according to a variety of international standards, such as European Pharmacopoeia (Fialuridine EP), Fialuridine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Fialuridine USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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