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    Chemistry

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    Also known as: 73231-34-2, Nuflor, (-)-florfenicol, Sch-25298, 76639-94-6, Sch 25298
    Molecular Formula
    C12H14Cl2FNO4S
    Molecular Weight
    358.2  g/mol
    InChI Key
    AYIRNRDRBQJXIF-NXEZZACHSA-N
    FDA UNII
    9J97307Y1H
    Florfenicol
    Florfenicol is a fluorinated synthetic analog of thiamphenicol.
    1 2D Structure

    Florfenicol

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    2,2-dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide
    2.1.2 InChI
    InChI=1S/C12H14Cl2FNO4S/c1-21(19,20)8-4-2-7(3-5-8)10(17)9(6-15)16-12(18)11(13)14/h2-5,9-11,17H,6H2,1H3,(H,16,18)/t9-,10-/m1/s1
    2.1.3 InChI Key
    AYIRNRDRBQJXIF-NXEZZACHSA-N
    2.1.4 Canonical SMILES
    CS(=O)(=O)C1=CC=C(C=C1)C(C(CF)NC(=O)C(Cl)Cl)O
    2.1.5 Isomeric SMILES
    CS(=O)(=O)C1=CC=C(C=C1)[C@H]([C@@H](CF)NC(=O)C(Cl)Cl)O
    2.2 Other Identifiers
    2.2.1 UNII
    9J97307Y1H
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 3-fluorothiamphenicol

    2. Chloramphen

    3. Florphenicol

    4. Sch 25298

    5. Sch-25298

    6. Thiamphenicol, 3-fluoro

    2.3.2 Depositor-Supplied Synonyms

    1. 73231-34-2

    2. Nuflor

    3. (-)-florfenicol

    4. Sch-25298

    5. 76639-94-6

    6. Sch 25298

    7. Nuflor Gold

    8. 2,2-dichloro-n-[(1r,2s)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide

    9. Chebi:87185

    10. D-threo-2,2-dichloro-n-(alpha-(fluoromethyl)-beta-hydroxy-p-(methylsulfonyl)phenethyl)acetamide

    11. 9j97307y1h

    12. Nsc-759287

    13. Acetamide, 2,2-dichloro-n-((1s,2r)-1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulfonyl)phenyl)ethyl)-

    14. Aquafen

    15. 2,2-dichloro-n-((1r,2s)-3-fluoro-1-hydroxy-1-(4-(methylsulfonyl)phenyl)propan-2-yl)acetamide

    16. 2,2-dichloro-n-[(1r,2s)-3-fluoro-1-hydroxy-1-(4-methanesulfonylphenyl)propan-2-yl]acetamide

    17. Dsstox_cid_25500

    18. Dsstox_rid_80918

    19. Dsstox_gsid_45500

    20. Acetamide, 2,2-dichloro-n-(1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulfonyl)phenyl)ethyl)-, (r-(r*,s*))-

    21. 2,2-dichloro-n-[(1r,2s)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)-2-propyl]acetamide

    22. D-(-)-threo-2-dichloroacetamido-3-fluoro-1-(4-methylsulfonylphenyl)-1-propanol

    23. Florfenicol [usan:inn:ban]

    24. 2,2-dichloro-n-(1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulfonyl)phenyl)ethyl)acetamide

    25. Unii-9j97307y1h

    26. 2,2-dichloro-n-((1r,2s)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)-2-propyl)acetamide

    27. Ncgc00016922-01

    28. Cas-73231-34-2

    29. Mfcd00864834

    30. Nuflor (tn)

    31. Florfenicol [mi]

    32. Prestwick0_000955

    33. Prestwick1_000955

    34. Prestwick2_000955

    35. Prestwick3_000955

    36. Florfenicol [inn]

    37. Florfenicol [jan]

    38. Florfenicol (usan/inn)

    39. Florfenicol [usan]

    40. Florfenicol [mart.]

    41. Schembl49425

    42. Bspbio_000950

    43. Mls002154071

    44. Spbio_003099

    45. Bpbio1_001046

    46. Chembl1241590

    47. Dtxsid9045500

    48. Florfenicol [green Book]

    49. Schembl21835523

    50. (-)-florfenicol;sch-25298

    51. Hms1570p12

    52. Hms2090i10

    53. Hms2097p12

    54. Hms2230k18

    55. Hms3714p12

    56. Zinc537733

    57. Act06682

    58. Hy-b1374

    59. Osurnia Component Florfenicol

    60. Zeleris Component Florfenicol

    61. Tox21_110683

    62. S4201

    63. Akos015889457

    64. Tox21_110683_1

    65. Ac-4340

    66. Ccg-220955

    67. Cs-4857

    68. Db11413

    69. Florfenicol Component Of Osurnia

    70. Florfenicol Component Of Zeleris

    71. Ks-5028

    72. Nsc 759287

    73. 2,2-dichloro-n-[(1s,2r)-1-(fluoromethyl)-2-hydroxy-2-(4-methylsulfonylphenyl)ethyl]acetamide

    74. Florfenicol [ema Epar Veterinary]

    75. Ncgc00179366-01

    76. Ncgc00179366-03

    77. Ncgc00179366-04

    78. 2,2-dichloro-n-((alphas,betar)-alpha-(fluoromethyl)-beta-hydroxy-p-(methylsulfonyl)phenethyl)acetamide

    79. Benzenesulfonic Acid, 4-(2-((dichloroacetyl)amino)-3-fluoro-1-hydroxypropyl)-, Methyl Ester, (r-(r*,s*))-

    80. Bf166386

    81. Smr001233384

    82. (methylsulfonyl)phenyl)propan-2-yl)acetamide

    83. Ab00513976

    84. F0811

    85. Sw197224-3

    86. D04194

    87. T72886

    88. Ab00513976_09

    89. 231f342

    90. A838774

    91. Q408400

    92. Florfenicol, Analytical Standard, For Drug Analysis

    93. Brd-k11298197-001-03-9

    94. 2,2-dichloro-n-((1r,2s)-3-fluoro-1-hydroxy-1-(4-

    95. (1r,2s)-2-dichloroacetamido-3-fluoro-1-[4-(methylsulfonyl) Phenyl]-1-propanol

    96. (1r,2s)-2-dichloroacetamido-3-fluoro-1-[4-(methylsulfonyl)phenyl]-1-propanol

    97. 2,2-dichlor-n-((1r,2s)-3-fluor-1-hydroxy- 1-(4-(methylsulfonyl)-phenyl)-propan-2-yl)-ethanamide

    98. 2,2-dichloro-n-((.alpha.s,.beta.r)-.alpha.-(fluoromethyl)-.beta.-hydroxy-p-(methylsulfonyl)phenethyl)acetamide

    99. 2,2-dichloro-n-[(1r,2r)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide

    100. 2,2-dichloro-n-{(1r,2s)-3-fluoro-1-hydroxy-1-[4-(methanesulfonyl)phenyl]propan-2-yl}acetamide

    101. D-threo-2,2-dichloro-n-(.alpha.-(fluoromethyl)-.beta.-hydroxy-p-(methylsulfonyl)phenethyl)acetamide

    2.4 Create Date
    2005-08-08
    3 Chemical and Physical Properties
    Molecular Weight 358.2 g/mol
    Molecular Formula C12H14Cl2FNO4S
    XLogP30.8
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count5
    Rotatable Bond Count6
    Exact Mass357.0004627 g/mol
    Monoisotopic Mass357.0004627 g/mol
    Topological Polar Surface Area91.8 Ų
    Heavy Atom Count21
    Formal Charge0
    Complexity447
    Isotope Atom Count0
    Defined Atom Stereocenter Count2
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Anti-Bacterial Agents

    Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)

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    Suanfarma

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    About the Company : Suanfarma founded in 1993, is a B2B life science partner committed to health & innovation by developing, manufacturing, & distributing high-quality APIs for the pharmaceutical indu...

    Suanfarma founded in 1993, is a B2B life science partner committed to health & innovation by developing, manufacturing, & distributing high-quality APIs for the pharmaceutical industry innovatively & sustainably. Backed by a robust global network of 12 strategically located local offices, we cater to the needs of over 400 active customers in 70+ countries. At Suanfarma we offer our CDMO capacity for fermentation & chemical synthesis projects, offering a One Stop Shop service with a solid track record, & which allows us to achieve success in the development, scaling, manufacturing, & commercialization of an API, either innovative or generic.
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    Rochem International Inc

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    About the Company : Established in 1994, Rochem is a distributor of pharmaceutical, food, nutritional and animal health ingredients to some of the largest companies in the world. It sources high-quali...

    Established in 1994, Rochem is a distributor of pharmaceutical, food, nutritional and animal health ingredients to some of the largest companies in the world. It sources high-quality ingredients manufactured in China. Headquartered in the Hauppauge, New York, Rochem has 16 offices spread across the globe to cater to the needs of its customers. Rochem’s operations are fully cGMP compliant and has been audited by the USFDA as well as several multinational organizations. It also trains and audits its partners to ensure all of their technologies and systems are FDA-compliant.
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    Temad Co

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    About the Company : Established in 1997, Temad Co. is one of the largest producers of APIs in Iran & an innovative manufacturer of narcotic and non-narcotic products of world-class quality in the Midd...

    Established in 1997, Temad Co. is one of the largest producers of APIs in Iran & an innovative manufacturer of narcotic and non-narcotic products of world-class quality in the Middle East. Apart from complying with Iranian GMP regulations, Temad has acquired the national & international standards of API manufacturing such as ISO 9001/14001/17025/45001 and OHSAS 18001. It currently manufactures more than 115 pharmaceutical products, including narcotics and non-narcotics, in accordance with GMP and WHO standards and regulations. Temad exports its products to 45 countries worldwide.
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    Anhui Sinotech Industrial

    China
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    Anhui Sinotech Industrial

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    About the Company : Anhui Sinotech Industrial Co.,Ltd is specially engaged in international marketing of food/feed additive,pesticides and chemicals. We are devoted ourselves to make the life better,a...

    Anhui Sinotech Industrial Co.,Ltd is specially engaged in international marketing of food/feed additive,pesticides and chemicals. We are devoted ourselves to make the life better,always ready to provide top quality products combined with competitive price and comprehensive commercial service. By continuously efforts,the company has already established stable long-term business relationships with hundreds of oversea customers and domestic suppliers.Our products has exported to many countries and regions, including Southeast Asia,South America, Europe,etc.
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    Grand Health Industrial Co Ltd

    China
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    About the Company : We can help your company solve the payment problems during the trading from chinese factories. We supply you with OEM from china.We are professsionals with the competitive price an...

    We can help your company solve the payment problems during the trading from chinese factories. We supply you with OEM from china.We are professsionals with the competitive price and high quality.We help you with professional regulation affair.We help you on documentation and systematizing quality control with factories. We assist you in purchasing and negotiating with various suppliers from China.We are your reliable tool and Platform around chemical ,pharmaceutical and pharm-bottle . We believe in trust and quality-reputation.
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    Hainan Haiyao

    China
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    Hainan Haiyao

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    About the Company : Hainan Haiyao is a national enterprise of high technology that integrates the research, development, production and sales of traditional Chinese medicine, antibiotic and oncology p...

    Hainan Haiyao is a national enterprise of high technology that integrates the research, development, production and sales of traditional Chinese medicine, antibiotic and oncology products medicine, API, etc. The company's main products cover the fields of intermediates, APIs, innovative chemical drugs, modern Chinese medicines, biological drugs, cellular immunity, and high-end medical devices. It has intermediates and API bases in Chongqing and Jiangsu, and preparations in Tianjin and Hainan.
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    Hangzhou Think Chemical Co.Ltd

    China
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    Hangzhou Think Chemical Co.Ltd

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    About the Company : HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of trade, research and contract manufacture. With about ten years of business experiences on the marketi...

    HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of trade, research and contract manufacture. With about ten years of business experiences on the marketing & distribution, Thinkchem specializes in exporting pharmaceuticals, veterinary drugs, feed additives, intermediates, fine chemicals, plants extracts, pesticides, food & nutrition additives. Thinkchem is good at offering excellent outsourcing services to overseas customers as well as laboratory support. Thinkchem is equipped with modern lab apparatus including HPLC, GC. TLC AND NMR, motivated by a team of highly qualified personnel using these equipments.
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    Hebei Veyong Pharmaceutical

    China
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    Hebei Veyong Pharmaceutical

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    About the Company : Hebei Veyong Pharmaceutical Co., Ltd, was established in 2002 and located in Economic and Technological Development Zone in Shijiazhuang. It is a large veterinary enterprise with G...

    Hebei Veyong Pharmaceutical Co., Ltd, was established in 2002 and located in Economic and Technological Development Zone in Shijiazhuang. It is a large veterinary enterprise with GMP certificate in China with research and development, production and sales of veterinary API and preparations. It is national high-tech enterprise, Hebei famous trademark enterprise, the vice-chairman company of Hebei Association of Animal Science and Veterinary Medicine, the vice-chairman company of Hebei Animal Health Products Association.
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    Hengdian Group

    China
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    About the Company : HENGDIAN GROUP was established in 1975, till now it has become a transnational,conglomerate group and been one of the largest private-owned enterprises in China. The Pharmaceutical...

    HENGDIAN GROUP was established in 1975, till now it has become a transnational,conglomerate group and been one of the largest private-owned enterprises in China. The Pharmaceutical & Chemical division has 3 sub-companies with over 3,000 employees of which over 30% are technicians; This division is mainly producing APIs, Agrochemical and Dyestuffs with related intermediates as well as other special chemicals. The group also focuses on CONTRACT MANUFACTURE service under GMP and confidential agreement with our clients.
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    Nanjing Dorra Pharmaceutical Techno...

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    About the Company : Dorrapharma is engaged in R&D, manufacture and market of intermediate, API (Active Pharmaceutical Ingredients) and formulation. We stick to raise the value both for the company and...

    Dorrapharma is engaged in R&D, manufacture and market of intermediate, API (Active Pharmaceutical Ingredients) and formulation. We stick to raise the value both for the company and customer, and strive for serving for the society and caring of the others. We devote ourselves completely to the technology innovation and brand build, and make every effort to foster the core competence for the company. We are in a progress of becoming a global leading pharmaceutical server.
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    [{"dataSource":"API Import","activeIngredients":"FLORFENICOL","year":"2021","qtr":"Q2","strtotime":1620930600,"product":"FLORFENICOL (INV NO.IMT06XSCP202104230201 DT.07.05.2021) (15000GMS","address":"3 AMARPARK APARTMENT, 1205\/2\/1,SHI ROLE ROAD, SHIVAJI NAGAR","city":"PUNE,MAHARASHTRA","supplier":"HUBEI MASTEAM BIO-TECH","supplierCountry":"CHINA","foreign_port":"WUHAN","customer":"VEKO CARE PRIVATE ","customerCountry":"INDIA","quantity":"15.00","actualQuantity":"15","unit":"KGS","unitRateFc":"103.5","totalValueFC":"1584.3","currency":"USD","unitRateINR":"7736.6","date":"14-May-2021","totalValueINR":"116049.38","totalValueInUsd":"1584.3","indian_port":"BOMBAY AIR","hs_no":"29414000","bill_no":"3949693","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"WUHAN","supplierAddress":"","customerAddress":"3 AMARPARK APARTMENT, 1205\/2\/1,SHI ROLE ROAD, SHIVAJI NAGAR"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q3","strtotime":1659033000,"product":"FLORFENICOL (FOR R & D PURPOSE)","address":"5TH FLOOR ENKAY CENTRE A BLOCK,,VA NIJYA NIKUNJ UDYOG VIHAR PHASE V","city":"GURGAON,HARYANA","supplier":"SHANDONG GUOBANG PHARMACEUTICAL ","supplierCountry":"CHINA","foreign_port":"NA","customer":"FELIX GENERICS PRIVATE ","customerCountry":"INDIA","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"325","totalValueFC":"1654.3","currency":"USD","unitRateINR":"26308.8","date":"29-Jul-2022","totalValueINR":"131543.75","totalValueInUsd":"1654.3","indian_port":"DELHI AIR","hs_no":"29329990","bill_no":"9775165","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"5TH FLOOR ENKAY CENTRE A BLOCK,,VA NIJYA NIKUNJ UDYOG VIHAR PHASE V"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1665685800,"product":"FLORFENICOL","address":"PLOT NO-51,MEENAKSHI BAMBOO,GACHIB","city":"HYDERABAD,TELANGANA","supplier":"ZHEJIANG HISOAR PHARMACEUTICAL","supplierCountry":"CHINA","foreign_port":"N\/A","customer":"CRONUS PHARMA SPECIALITIES ","customerCountry":"INDIA","quantity":"17.00","actualQuantity":"17","unit":"KGS","unitRateFc":"243.8","totalValueFC":"4153.2","currency":"USD","unitRateINR":"20102.3","date":"14-Oct-2022","totalValueINR":"341739","totalValueInUsd":"4153.2","indian_port":"GMR HYDERABAD AVIATION-SEZ","hs_no":"29414000","bill_no":"1004764","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"N\/A","supplierAddress":"NO. 23 5TH DONGHAI AVENUE ZHEJIANG CHEMICAL MATERIALS BASE LINHAI ZONE","customerAddress":"PLOT NO-51,MEENAKSHI BAMBOO,GACHIB"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1671129000,"product":"FLORFENICOL","address":"PLOT NO-51,MEENAKSHI BAMBOO,GACHIB","city":"HYDERABAD,TELANGANA","supplier":"ZHEJIANG HISOAR PHARMACEUTICAL","supplierCountry":"CHINA","foreign_port":"PUDONG\/SHANGHAI","customer":"CRONUS PHARMA SPECIALITIES ","customerCountry":"INDIA","quantity":"147.00","actualQuantity":"147","unit":"KGS","unitRateFc":"230.3","totalValueFC":"34328.2","currency":"USD","unitRateINR":"19244","date":"16-Dec-2022","totalValueINR":"2828861","totalValueInUsd":"34328.2","indian_port":"GMR HYDERABAD AVIATION-SEZ","hs_no":"29414000","bill_no":"1005932","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"PUDONG\/SHANGHAI","supplierAddress":"N\/A","customerAddress":"PLOT NO-51,MEENAKSHI BAMBOO,GACHIB"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1706034600,"product":"FLORFENICOL","address":"PLOT NO-51,MEENAKSHI BAMBOO,GACHIB","city":"HYDERABAD,TELANGANA","supplier":"ZHEJIANG HISOAR PHARMACEUTICAL","supplierCountry":"CHINA","foreign_port":"N\/A","customer":"CRONUS PHARMA SPECIALITIES ","customerCountry":"INDIA","quantity":"2369.00","actualQuantity":"2369","unit":"KGS","unitRateFc":"198","totalValueFC":"474651.7","currency":"USD","unitRateINR":"16652.2","date":"24-Jan-2024","totalValueINR":"39449113","totalValueInUsd":"474651.7","indian_port":"GMR HYDERABAD AVIATION-SEZ","hs_no":"29414000","bill_no":"1000560","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"N\/A","supplierAddress":"NO. 23 5TH DONGHAI AVENUE ZHEJIANG CHEMICAL MATERIALS BASE LINHAI ZONE","customerAddress":"PLOT NO-51,MEENAKSHI BAMBOO,GACHIB"}]
    14-May-2021
    24-Jan-2024
    KGS
    overview
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    Average Price (USD/KGS)

    Number of Transactions

    Total Quantity (KGS)

    Total Value (USD)

    Quantity (KGS) & Unit rate (USD/KGS) over time

    API Imports and Exports

    Importing Country Total Quantity
    (KGS)    		 Average Price
    (USD/KGS)    		 Number of Transactions

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