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Chemistry

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Also known as: Floxacillin, 5250-39-5, Floxapen, Flucloxacilina, Flucloxacilline, Flucloxacillinum
Molecular Formula
C19H17ClFN3O5S
Molecular Weight
453.9  g/mol
InChI Key
UIOFUWFRIANQPC-JKIFEVAISA-N
FDA UNII
43B2M34G2V

Floxacillin
Antibiotic analog of CLOXACILLIN.
1 2D Structure

Floxacillin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2S,5R,6R)-6-[[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
2.1.2 InChI
InChI=1S/C19H17ClFN3O5S/c1-7-10(12(23-29-7)11-8(20)5-4-6-9(11)21)15(25)22-13-16(26)24-14(18(27)28)19(2,3)30-17(13)24/h4-6,13-14,17H,1-3H3,(H,22,25)(H,27,28)/t13-,14+,17-/m1/s1
2.1.3 InChI Key
UIOFUWFRIANQPC-JKIFEVAISA-N
2.1.4 Canonical SMILES
CC1=C(C(=NO1)C2=C(C=CC=C2Cl)F)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C(=O)O
2.1.5 Isomeric SMILES
CC1=C(C(=NO1)C2=C(C=CC=C2Cl)F)C(=O)N[C@H]3[C@@H]4N(C3=O)[C@H](C(S4)(C)C)C(=O)O
2.2 Other Identifiers
2.2.1 UNII
43B2M34G2V
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Floxacillin

2. Fluorochloroxacillin

2.3.2 Depositor-Supplied Synonyms

1. Floxacillin

2. 5250-39-5

3. Floxapen

4. Flucloxacilina

5. Flucloxacilline

6. Flucloxacillinum

7. Floxacillin [usan]

8. Flucloxacillin Sodium

9. Flucloxacilina [inn-spanish]

10. Flucloxacilline [inn-french]

11. Flucloxacillinum [inn-latin]

12. Brl 2039

13. 3-(2-chloro-6-fluorophenyl)-5-methyl-4-isoxazolylpenicillin

14. Flucloxacillin-sodium

15. Chebi:5098

16. Floxacillin (usan)

17. Flucloxacillin (inn)

18. Flucloxacillin [inn]

19. Brl-2039

20. Floxapen (tn)

21. (2s,5r,6r)-6-[[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid

22. 43b2m34g2v

23. (2s,5r,6r)-6-({[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid

24. 6-(3-(2-chloro-6-fluorophenyl)-5-methyl-4-isoxazolecarboxamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid

25. Floxacillin Sodium Anhydrous

26. Flucloxacillin Sodium Anhydrous

27. 4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid,6-[[[3-(2-chloro-6-fluorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-,(2s,5r,6r)-

28. Mfipc

29. Nsc-277175

30. Einecs 226-051-0

31. Unii-43b2m34g2v

32. Flucloxacillin,(s)

33. Floxacillin [mi]

34. Epitope Id:117416

35. Schembl3823

36. 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 6-(((3-(2-chloro-6-fluorophenyl)-5-methyl-4-isoxazolyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, (2s(2alpha,5alpha,6beta))

37. Flucloxacillin [mart.]

38. Chembl222645

39. Flucloxacillin [who-dd]

40. Dtxsid8023056

41. Gtpl10910

42. Brl2039

43. Hy-a0246

44. Zinc4102187

45. Bdbm50370590

46. Db00301

47. Ncgc00485420-01

48. (2s,5r,6r)-6-({[3-(2-chloro-6-fluorophenyl)-5-methylisoxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid

49. (2s,5r,6r)-6-[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid

50. 6beta-[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carboxamido]-2,2-dimethylpenam-3alpha-carboxylic Acid

51. Nci60_002254

52. Cs-0017591

53. D04196

54. 250f395

55. Q1994556

56. W-105817

57. Brd-k27871792-001-01-8

58. Flucloxacillin, Antibiotic For Culture Media Use Only

59. (2s,5r,6r)-6-(3-(2-chloro-6-fluorophenyl)-5-methylisoxazole-4-carboxamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid

60. 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 6-(((3-(2-chloro-6-fluorophenyl)-5-methyl-4-isoxazolyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, (2s(2.alpha.,5.alpha.,6.beta.))

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 453.9 g/mol
Molecular Formula C19H17ClFN3O5S
XLogP32.6
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count4
Exact Mass453.0561477 g/mol
Monoisotopic Mass453.0561477 g/mol
Topological Polar Surface Area138 Ų
Heavy Atom Count30
Formal Charge0
Complexity758
Isotope Atom Count0
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Indication

Used to treat bacterial infection by susceptible microorganisms.


5 Pharmacology and Biochemistry
5.1 Pharmacology

Flucloxacillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. The name "penicillin" can either refer to several variants of penicillin available, or to the group of antibiotics derived from the penicillins. Flucloxacillin has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria. The bactericidal activity of Flucloxacillin results from the inhibition of cell wall synthesis and is mediated through flucloxacillin binding to penicillin binding proteins (PBPs). Flucloxacillin is stable against hydrolysis by a variety of beta-lactamases, including penicillinases, and cephalosporinases and extended spectrum beta-lactamases.


5.2 MeSH Pharmacological Classification

Anti-Bacterial Agents

Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)


5.3 ATC Code

J01CF05

S76 | LUXPHARMA | Pharmaceuticals Marketed in Luxembourg | Pharmaceuticals marketed in Luxembourg, as published by d'Gesondheetskeess (CNS, la caisse nationale de sante, www.cns.lu), mapped by name to structures using CompTox by R. Singh et al. (in prep.). List downloaded from https://cns.public.lu/en/legislations/textes-coordonnes/liste-med-comm.html. Dataset DOI:10.5281/zenodo.4587355


J - Antiinfectives for systemic use

J01 - Antibacterials for systemic use

J01C - Beta-lactam antibacterials, penicillins

J01CF - Beta-lactamase resistant penicillins

J01CF05 - Flucloxacillin


5.4 Absorption, Distribution and Excretion

Absorption

Bioavailability is 5070% following oral administration.


5.5 Metabolism/Metabolites

Hepatic.


Flucloxacillin has known human metabolites that include 6-[[3-(2-Chloro-6-fluorophenyl)-5-(hydroxymethyl)-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid.

S73 | METXBIODB | Metabolite Reaction Database from BioTransformer | DOI:10.5281/zenodo.4056560


5.6 Biological Half-Life

0.751 hour


5.7 Mechanism of Action

By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, flucloxacillin inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that flucloxacillin interferes with an autolysin inhibitor.


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KGAA","supplierCountry":"ITALY","foreign_port":"NA","customer":"MICRO LABS LIMITED","customerCountry":"INDIA","quantity":"200.00","actualQuantity":"200","unit":"KGS","unitRateFc":"80","totalValueFC":"16428.8","currency":"USD","unitRateINR":"6704","date":"15-Nov-2022","totalValueINR":"1340800","totalValueInUsd":"16428.8","indian_port":"MADRAS AIR","hs_no":"29411090","bill_no":"3305532","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"NO 31, RACE COURSE ROAD BANGALORE Contact No: 919945641620"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1684089000,"product":"FLUCLOXACILLIN SODIUM COMPACTED","address":"7\/1,CORPORATE PARK,SION-TROMBAY","city":"MUMBAI","supplier":"FRESENIUS KABI IPSUM SRL","supplierCountry":"ITALY","foreign_port":"N\/A","customer":"FLAMINGO PHARMACEUTICALS LIMITED","customerCountry":"INDIA","quantity":"1997.00","actualQuantity":"1997","unit":"KGS","unitRateFc":"80","totalValueFC":"160373.1","currency":"USD","unitRateINR":"6608","date":"15-May-2023","totalValueINR":"13196176","totalValueInUsd":"160373.1","indian_port":"MIDC SEZ\/Nanded","hs_no":"29411090","bill_no":"1000038","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"N\/A","supplierAddress":"N\/A","customerAddress":"7\/1,CORPORATE PARK,SION-TROMBAY"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1689618600,"product":"FLUCLOXACILLIN SODIUM (COMPACTED) EP\/BP","address":"NO 31, RACE COURSE ROAD BANGALORE Contact No: 919945641620","city":"BENGALURU","supplier":"FRESENIUS SE & CO. KGAA","supplierCountry":"ITALY","foreign_port":"NA","customer":"MICRO LABS LIMITED","customerCountry":"INDIA","quantity":"166.63","actualQuantity":"166.63","unit":"KGS","unitRateFc":"80","totalValueFC":"13502.4","currency":"USD","unitRateINR":"6659.8","date":"18-Jul-2023","totalValueINR":"1109755.92","totalValueInUsd":"13502.4","indian_port":"MADRAS AIR","hs_no":"29411090","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"NO 31, RACE COURSE ROAD BANGALORE Contact No: 919945641620"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1702492200,"product":"FLUCLOXACILLIN SODIUM (COMPACTED) EP","address":"NO 31, RACE COURSE ROAD,BANGALORE","city":"BENGALURU,KARNATAKA","supplier":"FRESENIUS KABI IPSUM S.R.L,","supplierCountry":"ITALY","foreign_port":"MILAN","customer":"MICRO LABS LIMITED","customerCountry":"INDIA","quantity":"575.00","actualQuantity":"575","unit":"KGS","unitRateFc":"80","totalValueFC":"46584","currency":"USD","unitRateINR":"6744","date":"14-Dec-2023","totalValueINR":"3877800","totalValueInUsd":"46584","indian_port":"Madras Air","hs_no":"29411090","bill_no":"9223282","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"MILAN","supplierAddress":"VIA ROMA, 10820051 CASSINA DE PECCHIMILANO ITALY","customerAddress":"NO 31, RACE COURSE ROAD,BANGALORE"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1705861800,"product":"FLUCLOXACILLIN SODIUM (COMPACTED) EP","address":"NO 31, RACE COURSE ROAD,BANGALORE","city":"BENGALURU,KARNATAKA","supplier":"FRESENIUS KABI IPSUM S.R.L,","supplierCountry":"ITALY","foreign_port":"MILAN - MALPENSA","customer":"MICRO LABS LIMITED","customerCountry":"INDIA","quantity":"2854.00","actualQuantity":"2854","unit":"KGS","unitRateFc":"72.5","totalValueFC":"209375.5","currency":"USD","unitRateINR":"6097.3","date":"22-Jan-2024","totalValueINR":"17401551.5","totalValueInUsd":"209375.5","indian_port":"Madras Air","hs_no":"29411090","bill_no":"9773132","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"MILAN - MALPENSA","supplierAddress":"VIA ROMA, 10820051 CASSINA DE PECCHIMILANO ITALY","customerAddress":"NO 31, RACE COURSE ROAD,BANGALORE"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1721154600,"product":"FLUCLOXACILLIN SODIUM (COMPACTED) EP","address":"NO 31, RACE COURSE ROAD,BANGALORE","city":"BENGALURU,KARNATAKA","supplier":"FRESENIUS KABI IPSUM S.R.L,","supplierCountry":"ITALY","foreign_port":"MILAN - MALPENSA","customer":"MICRO LABS LIMITED","customerCountry":"INDIA","quantity":"211.01","actualQuantity":"211.009","unit":"KGS","unitRateFc":"80","totalValueFC":"17054.2","currency":"USD","unitRateINR":"6756","date":"17-Jul-2024","totalValueINR":"1425576.8","totalValueInUsd":"17054.2","indian_port":"Madras Air","hs_no":"29411090","bill_no":"4550073","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"MILAN - MALPENSA","supplierAddress":"VIA ROMA, 10820051 CASSINA DE PECCHIMILANO ITALY","customerAddress":"NO 31, RACE COURSE ROAD,BANGALORE"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1722364200,"product":"FLUCLOXACILLIN SODIUM COMPACTED","address":"MEDREICH HOUSE, NO12\/8,","city":"SEVA NAGAR, BANGALORE, KARNATAKA","supplier":"FRESENIUS SE & CO. KGAA","supplierCountry":"ITALY","foreign_port":"MILAN","customer":"MEDREICH","customerCountry":"INDIA","quantity":"575.00","actualQuantity":"575","unit":"KGS","unitRateFc":"75","totalValueFC":"43619.7","currency":"USD","unitRateINR":"6341.3","date":"31-Jul-2024","totalValueINR":"3646218.75","totalValueInUsd":"43619.7","indian_port":"Bangalore Air","hs_no":"29411090","bill_no":"4808897","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"MILAN","supplierAddress":"VIA ROMA, 10820051 CASSINA DE PECCHI MILANOSDNF ITALY","customerAddress":"MEDREICH HOUSE, NO12\/8,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1730226600,"product":"FLUCLOXACILLIN SODIUM COMPACTED","address":"MEDREICH HOUSE, NO12\/8,","city":"SEVA NAGAR, BANGALORE, KARNATAKA","supplier":"FRESENIUS SE & CO. KGAA","supplierCountry":"ITALY","foreign_port":"MILAN","customer":"MEDREICH","customerCountry":"INDIA","quantity":"400.00","actualQuantity":"400","unit":"KGS","unitRateFc":"75","totalValueFC":"30329.7","currency":"USD","unitRateINR":"6371.3","date":"30-Oct-2024","totalValueINR":"2548500","totalValueInUsd":"30329.7","indian_port":"Bangalore Air","hs_no":"29411090","bill_no":"6410332","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"MILAN","supplierAddress":"VIA ROMA, 108 20051 CASSINA DE PECCHI MILANO SDNF ITALY","customerAddress":"MEDREICH HOUSE, NO12\/8,"}]
07-Jan-2021
30-Oct-2024
KGS
overview
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Average Price (USD/KGS)

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country Total Quantity
(KGS)
Average Price
(USD/KGS)
Number of Transactions

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FDF Dossiers

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01

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Compamed
Not Confirmed

Flucloxacillin

Brand Name : Suprapen 500

Dosage Form : CAP

Dosage Strength : 250mg

Packaging : 100X1mg

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : South Africa

Aspen API Comapny Banner

02

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Compamed
Not Confirmed

Flucloxacillin

Brand Name : Megapen 500

Dosage Form : CAP

Dosage Strength : 250mg

Packaging : 15X1mg

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : South Africa

Aspen API Comapny Banner

03

arrow
Compamed
Not Confirmed

Flucloxacillin

Brand Name : Megapen 500

Dosage Form : CAP

Dosage Strength : 250mg

Packaging : 100X1mg

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : South Africa

Aspen API Comapny Banner

04

arrow
Compamed
Not Confirmed

Flucloxacillin

Brand Name : Floxapen

Dosage Form : SUS

Dosage Strength : 125mg/ 5ml

Packaging : 100X1mg/ 5ml

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : South Africa

Aspen API Comapny Banner

05

arrow
Compamed
Not Confirmed

Flucloxacillin

Brand Name : Megapen S

Dosage Form : SUS

Dosage Strength : 125mg/5ml

Packaging : 100X1mg/5ml

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : South Africa

Aspen API Comapny Banner

06

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Compamed
Not Confirmed

flucloxacillin

Brand Name : Flucil

Dosage Form :

Dosage Strength :

Packaging : 5

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Australia

Aspen API Comapny Banner

07

arrow
Compamed
Not Confirmed

flucloxacillin

Brand Name : Flucil

Dosage Form :

Dosage Strength :

Packaging : 5

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Australia

Aspen API Comapny Banner

08

arrow
Compamed
Not Confirmed

flucloxacillin

Brand Name : Flucil

Dosage Form :

Dosage Strength :

Packaging : 1

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Australia

Aspen API Comapny Banner

09

arrow
Compamed
Not Confirmed

flucloxacillin

Brand Name : Flucil

Dosage Form :

Dosage Strength :

Packaging : 1

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Australia

Aspen API Comapny Banner

10

arrow
Compamed
Not Confirmed

flucloxacillin

Brand Name : Flucil

Dosage Form :

Dosage Strength :

Packaging : 1

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Australia

Aspen API Comapny Banner
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Europe

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01

Compamed
Not Confirmed
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arrow
Compamed
Not Confirmed

Floxacillin

Brand Name : Flucacid

Dosage Form : Flucloxacillin 1.000Mg 12 Combined Oral Use

Dosage Strength : 12 CPR 1 g

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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02

Compamed
Not Confirmed
arrow
arrow
Compamed
Not Confirmed

Floxacillin

Brand Name : Flucloxacillin

Dosage Form : Flucoxacillina 1.000Mg 100 Unita' Parenteral Use

Dosage Strength : 100 bottles groun soluz injector 1 g

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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03

Compamed
Not Confirmed
arrow
arrow
Compamed
Not Confirmed

Floxacillin

Brand Name : Flucloxacillin

Dosage Form : Flucoxacillina 1.000Mg 50 Joined The Parenteral Use

Dosage Strength : 50 bottles groun soluz injector 1 g

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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04

FARMA GROUP Srl

Country
Compamed
Not Confirmed
arrow

FARMA GROUP Srl

Country
arrow
Compamed
Not Confirmed

Floxacillin

Brand Name : Liderclox

Dosage Form : Flucloxacillin 1.000Mg 12 Combined Oral Use

Dosage Strength : 12 CPR 1 g

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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05

NEW RESEARCH Srl

Country
Compamed
Not Confirmed
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NEW RESEARCH Srl

Country
arrow
Compamed
Not Confirmed

Floxacillin

Brand Name : Nepenic

Dosage Form : Flucloxacillin 1.000Mg 12 Combined Oral Use

Dosage Strength : 12 CPR 1 g

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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06

RO-FARM.di DE MAIO SALVATORE&C

Country
Compamed
Not Confirmed
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RO-FARM.di DE MAIO SALVATORE&C

Country
arrow
Compamed
Not Confirmed

Floxacillin

Brand Name : Recaflux

Dosage Form : Flucloxacillin 1.000Mg 12 Combined Oral Use

Dosage Strength : 12 CPR 1 g

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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Canada

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01

Neogen N.V.

Belgium
Compamed
Not Confirmed
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Neogen N.V.

Belgium
arrow
Compamed
Not Confirmed

Floxacillin

Brand Name :

Dosage Form : FILM COATED TABLET

Dosage Strength : 500MG

Packaging :

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : Canada

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02

Neogen N.V.

Belgium
Compamed
Not Confirmed
arrow

Neogen N.V.

Belgium
arrow
Compamed
Not Confirmed

Floxacillin

Brand Name :

Dosage Form : FILM COATED TABLET

Dosage Strength : 750MG

Packaging :

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : Canada

blank

03

Neogen N.V.

Belgium
Compamed
Not Confirmed
arrow

Neogen N.V.

Belgium
arrow
Compamed
Not Confirmed

Floxacillin

Brand Name :

Dosage Form : FILM COATED TABLET

Dosage Strength : 1000MG

Packaging :

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : Canada

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Australia

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01

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Compamed
Not Confirmed

flucloxacillin

Brand Name : Flucil

Dosage Form :

Dosage Strength :

Packaging : 5

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Australia

Aspen API Comapny Banner

02

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Compamed
Not Confirmed

flucloxacillin

Brand Name : Flucil

Dosage Form :

Dosage Strength :

Packaging : 5

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Australia

Aspen API Comapny Banner

03

arrow
Compamed
Not Confirmed

flucloxacillin

Brand Name : Flucil

Dosage Form :

Dosage Strength :

Packaging : 1

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Australia

Aspen API Comapny Banner

04

arrow
Compamed
Not Confirmed

flucloxacillin

Brand Name : Flucil

Dosage Form :

Dosage Strength :

Packaging : 1

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Australia

Aspen API Comapny Banner

05

arrow
Compamed
Not Confirmed

flucloxacillin

Brand Name : Flucil

Dosage Form :

Dosage Strength :

Packaging : 1

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Australia

Aspen API Comapny Banner

06

arrow
Compamed
Not Confirmed

flucloxacillin

Brand Name : Flucil

Dosage Form :

Dosage Strength :

Packaging : 1

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Australia

Aspen API Comapny Banner

07

Alphapharm Pty Ltd

Australia
Compamed
Not Confirmed
arrow

Alphapharm Pty Ltd

Australia
arrow
Compamed
Not Confirmed

flucloxacillin

Brand Name : Flopen

Dosage Form : capsule

Dosage Strength : 500 mg

Packaging : 24

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Australia

blank

08

Alphapharm Pty Ltd

Australia
Compamed
Not Confirmed
arrow

Alphapharm Pty Ltd

Australia
arrow
Compamed
Not Confirmed

flucloxacillin

Brand Name : Flopen Viatris

Dosage Form : capsule

Dosage Strength : 500 mg

Packaging : 24

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Australia

blank

09

Alphapharm Pty Ltd

Australia
Compamed
Not Confirmed
arrow

Alphapharm Pty Ltd

Australia
arrow
Compamed
Not Confirmed

flucloxacillin

Brand Name : Staphylex 500

Dosage Form : capsule

Dosage Strength : 500 mg

Packaging : 24

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Australia

blank

10

Alphapharm Pty Ltd

Australia
Compamed
Not Confirmed
arrow

Alphapharm Pty Ltd

Australia
arrow
Compamed
Not Confirmed

flucloxacillin

Brand Name : Flopen Viatris

Dosage Form : capsule

Dosage Strength : 500 mg

Packaging : 24

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Australia

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South Africa

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01

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Compamed
Not Confirmed

Flucloxacillin

Brand Name : Floxapen

Dosage Form : CAP

Dosage Strength : 250mg

Packaging : 20X1mg

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : South Africa

Aspen API Comapny Banner

02

arrow
Compamed
Not Confirmed

Flucloxacillin

Brand Name : Suprapen 500

Dosage Form : CAP

Dosage Strength : 250mg

Packaging : 100X1mg

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : South Africa

Aspen API Comapny Banner

03

arrow
Compamed
Not Confirmed

Flucloxacillin

Brand Name : Megapen 500

Dosage Form : CAP

Dosage Strength : 250mg

Packaging : 15X1mg

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : South Africa

Aspen API Comapny Banner

04

arrow
Compamed
Not Confirmed

Flucloxacillin

Brand Name : Megapen 500

Dosage Form : CAP

Dosage Strength : 250mg

Packaging : 100X1mg

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : South Africa

Aspen API Comapny Banner

05

arrow
Compamed
Not Confirmed

Flucloxacillin

Brand Name : Floxapen

Dosage Form : SUS

Dosage Strength : 125mg/ 5ml

Packaging : 100X1mg/ 5ml

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : South Africa

Aspen API Comapny Banner

06

arrow
Compamed
Not Confirmed

Flucloxacillin

Brand Name : Megapen S

Dosage Form : SUS

Dosage Strength : 125mg/5ml

Packaging : 100X1mg/5ml

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : South Africa

Aspen API Comapny Banner

07

Compamed
Not Confirmed
arrow
arrow
Compamed
Not Confirmed

flucloxacillin

Brand Name : Septapen

Dosage Form : TAB

Dosage Strength : 250mg

Packaging : 20X1mg

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : South Africa

blank

08

Sandoz SA (Pty) Ltd

Switzerland
Compamed
Not Confirmed
arrow

Sandoz SA (Pty) Ltd

Switzerland
arrow
Compamed
Not Confirmed

Flucloxacillin

Brand Name : Sandoz Flucloxacillin 250

Dosage Form : CAP

Dosage Strength : 250mg

Packaging : 20X1mg

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : South Africa

blank

09

Xixia Pharmaceuticals (Pty) Ltd

Country
Compamed
Not Confirmed
arrow

Xixia Pharmaceuticals (Pty) Ltd

Country
arrow
Compamed
Not Confirmed

Flucloxacillin

Brand Name : Macropen 500

Dosage Form : CAP

Dosage Strength : 250mg

Packaging : 15X1mg

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : South Africa

blank

10

Xixia Pharmaceuticals (Pty) Ltd

Country
Compamed
Not Confirmed
arrow

Xixia Pharmaceuticals (Pty) Ltd

Country
arrow
Compamed
Not Confirmed

Flucloxacillin

Brand Name : Macropen 500

Dosage Form : CAP

Dosage Strength : 250mg

Packaging : 100X1mg

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : South Africa

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Listed Dossiers

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01

Compamed
Not Confirmed
arrow
arrow
Compamed
Not Confirmed

Floxacillin

Brand Name :

Dosage Form : Injection

Dosage Strength : 1GM/1Vial

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

blank

01

Compamed
Not Confirmed
arrow
arrow
Compamed
Not Confirmed

Floxacillin

Dosage : Injection

Dosage Strength : 1GM/1Vial

Brand Name :

Approval Date :

Application Number :

Registration Country : Italy

blank

02

Compamed
Not Confirmed
arrow
arrow
Compamed
Not Confirmed

Floxacillin

Brand Name :

Dosage Form : Injection

Dosage Strength : 2GM/1Vial

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

blank

02

Compamed
Not Confirmed
arrow
arrow
Compamed
Not Confirmed

Floxacillin

Dosage : Injection

Dosage Strength : 2GM/1Vial

Brand Name :

Approval Date :

Application Number :

Registration Country : Italy

blank

03

Compamed
Not Confirmed
arrow
arrow
Compamed
Not Confirmed

Floxacillin

Brand Name :

Dosage Form : Injection

Dosage Strength : 1G

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

blank

03

Compamed
Not Confirmed
arrow
arrow
Compamed
Not Confirmed

Floxacillin

Dosage : Injection

Dosage Strength : 1G

Brand Name :

Approval Date :

Application Number :

Registration Country : India

blank

04

Grupo Azevedos

Portugal
Compamed
Not Confirmed
arrow

Grupo Azevedos

Portugal
arrow
Compamed
Not Confirmed

Floxacillin

Brand Name :

Dosage Form : Capsules

Dosage Strength : 500MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Portugal

blank

04

Grupo Azevedos

Portugal
Compamed
Not Confirmed
arrow

Grupo Azevedos

Portugal
arrow
Compamed
Not Confirmed

Floxacillin

Dosage : Capsules

Dosage Strength : 500MG

Brand Name :

Approval Date :

Application Number :

Registration Country : Portugal

blank

05

Medreich

India
Compamed
Not Confirmed
arrow

Medreich

India
arrow
Compamed
Not Confirmed

Floxacillin

Brand Name :

Dosage Form : Tablet

Dosage Strength : 500MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

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05

Medreich

India
Compamed
Not Confirmed
arrow

Medreich

India
arrow
Compamed
Not Confirmed

Floxacillin

Dosage : Tablet

Dosage Strength : 500MG

Brand Name :

Approval Date :

Application Number :

Registration Country : India

blank

06

Medreich

India
Compamed
Not Confirmed
arrow

Medreich

India
arrow
Compamed
Not Confirmed

Floxacillin

Brand Name :

Dosage Form : Tablet

Dosage Strength : 750MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

blank

06

Medreich

India
Compamed
Not Confirmed
arrow

Medreich

India
arrow
Compamed
Not Confirmed

Floxacillin

Dosage : Tablet

Dosage Strength : 750MG

Brand Name :

Approval Date :

Application Number :

Registration Country : India

blank

07

Ria Generics

United Kingdom
Compamed
Not Confirmed
arrow

Ria Generics

United Kingdom
arrow
Compamed
Not Confirmed

Floxacillin

Brand Name :

Dosage Form : Oral

Dosage Strength : 250MG/5ML

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country :

blank

07

Ria Generics

United Kingdom
Compamed
Not Confirmed
arrow

Ria Generics

United Kingdom
arrow
Compamed
Not Confirmed

Floxacillin

Dosage : Oral

Dosage Strength : 250MG/5ML

Brand Name :

Approval Date :

Application Number :

Registration Country :

blank

08

Stragen Pharma SA

Switzerland
Compamed
Not Confirmed
arrow

Stragen Pharma SA

Switzerland
arrow
Compamed
Not Confirmed

Floxacillin

Brand Name :

Dosage Form : Powder for Solution fo...

Dosage Strength : 1G

Packaging : 1, 5, 10, 25, 50 and 100 vials

Approval Date :

Application Number :

Regulatory Info :

Registration Country :

blank

08

Stragen Pharma SA

Switzerland
Compamed
Not Confirmed
arrow

Stragen Pharma SA

Switzerland
arrow
Compamed
Not Confirmed

Floxacillin

Dosage : Powder for Solution fo...

Dosage Strength : 1G

Brand Name :

Approval Date :

Application Number :

Registration Country :

blank

09

Stragen Pharma SA

Switzerland
Compamed
Not Confirmed
arrow

Stragen Pharma SA

Switzerland
arrow
Compamed
Not Confirmed

Floxacillin

Brand Name :

Dosage Form : Powder for Solution fo...

Dosage Strength : 2G

Packaging : 1, 5, 10, 25, 50 and 100 vials

Approval Date :

Application Number :

Regulatory Info :

Registration Country :

blank

09

Stragen Pharma SA

Switzerland
Compamed
Not Confirmed
arrow

Stragen Pharma SA

Switzerland
arrow
Compamed
Not Confirmed

Floxacillin

Dosage : Powder for Solution fo...

Dosage Strength : 2G

Brand Name :

Approval Date :

Application Number :

Registration Country :

blank

10

Compamed
Not Confirmed
arrow
arrow
Compamed
Not Confirmed

Floxacillin

Brand Name : FLUCILLIN-250

Dosage Form : Capsule

Dosage Strength : 250MG

Packaging : 10x10’s PVDC Blisters

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

blank

10

Compamed
Not Confirmed
arrow
arrow
Compamed
Not Confirmed

Floxacillin

Dosage : Capsule

Dosage Strength : 250MG

Brand Name : FLUCILLIN-250

Approval Date :

Application Number :

Registration Country : India

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