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Chemistry

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Also known as: 38677-85-9, Flunixine, Sch 14714, Flunixino, Flunixinum, Sch-14714
Molecular Formula
C14H11F3N2O2
Molecular Weight
296.24  g/mol
InChI Key
NOOCSNJCXJYGPE-UHFFFAOYSA-N
FDA UNII
356IB1O400

Flunixin
Flunixin is a non-steroidal anti-inflammatory drug for use in pigs, cattle and horses. It exerts analgesic and antipyretic effects. This drug is often prepared for use in meglumine salt form. Flunixin is regulated in the United States by the Food and Drug Administration (FDA) and must be prescribed by a licensed veterinarian. Flunixin may be also referred to as Banamine, and other trade names.
1 2D Structure

Flunixin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-[2-methyl-3-(trifluoromethyl)anilino]pyridine-3-carboxylic acid
2.1.2 InChI
InChI=1S/C14H11F3N2O2/c1-8-10(14(15,16)17)5-2-6-11(8)19-12-9(13(20)21)4-3-7-18-12/h2-7H,1H3,(H,18,19)(H,20,21)
2.1.3 InChI Key
NOOCSNJCXJYGPE-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC1=C(C=CC=C1NC2=C(C=CC=N2)C(=O)O)C(F)(F)F
2.2 Other Identifiers
2.2.1 UNII
356IB1O400
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Sch 14714

2.3.2 Depositor-Supplied Synonyms

1. 38677-85-9

2. Flunixine

3. Sch 14714

4. Flunixino

5. Flunixinum

6. Sch-14714

7. 2-((2-methyl-3-(trifluoromethyl)phenyl)amino)nicotinic Acid

8. Chebi:76138

9. 2-{[2-methyl-3-(trifluoromethyl)phenyl]amino}nicotinic Acid

10. 2-[2-methyl-3-(trifluoromethyl)anilino]pyridine-3-carboxylic Acid

11. 356ib1o400

12. 2-[[2-methyl-3-(trifluoromethyl)phenyl]amino]pyridine-3-carboxylic Acid

13. 3-pyridinecarboxylic Acid, 2-((2-methyl-3-(trifluoromethyl)phenyl)amino)-

14. Flunixin [usan]

15. Flunixine [inn-french]

16. Flunixinum [inn-latin]

17. Flunixino [inn-spanish]

18. 2-((2-methyl-3-(trifluoromethyl)phenyl)amino)-3-pyridinecarboxylic Acid

19. 2-[[2-methyl-3-(trifluoromethyl)phenyl]amino]-3-pyridinecarboxylic Acid

20. 3-pyridinecarboxylic Acid, 2-[[2-methyl-3-(trifluoromethyl)phenyl]amino]-

21. Flunixin [usan:inn:ban]

22. Flunixin-meglumin

23. Unii-356ib1o400

24. 2(2'-methyl-3'-trifluoromethylanilino)nicotinic Acid

25. Flunixin (usan/inn)

26. Flunixin [inn]

27. Flunixin [mi]

28. 2-(alpha(sup 3),alpha(sup 3),alpha(sup 3)-trifluoro-2,3-xylidino)nicotinic Acid

29. Schembl42911

30. Mls004712071

31. Flunixin [green Book]

32. Sch14714

33. Zinc1467

34. Chembl1617398

35. Dtxsid4048565

36. 2-[2-methyl-3-(trifluoromethyl)phenylamino]nicotinic Acid

37. Bcp12991

38. Bdbm50201618

39. Mfcd00072033

40. Akos015963218

41. Ac-1265

42. Db11518

43. Flunixin 100 Microg/ml In Acetonitrile

44. Smr000857255

45. Ft-0626444

46. Flunixin, Vetranal(tm), Analytical Standard

47. Vu0244596-2

48. D04215

49. 677f859

50. Q906934

51. Sr-01000883753

52. Sr-01000883753-1

53. 2-(2-methyl-3-trifluoromethylanilino) Nicotinic Acid

54. Brd-k99984802-098-03-2

55. Brd-k99984802-100-01-0

56. Brd-k99984802-100-06-9

57. 2-(alpha(3),alpha(3),alpha(3)-trifluoro-2,3-xylidino)nicotinic Acid

58. 2-(.alpha.(sup 3),.alpha.(sup 3),.alpha.(sup 3)-trifluoro-2,3-xylidino)nicotinic Acid.

59. Jbo

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 296.24 g/mol
Molecular Formula C14H11F3N2O2
XLogP34.1
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count3
Exact Mass296.07726208 g/mol
Monoisotopic Mass296.07726208 g/mol
Topological Polar Surface Area62.2 Ų
Heavy Atom Count21
Formal Charge0
Complexity376
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anti-Inflammatory Agents, Non-Steroidal

Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)


Antipyretics

Drugs that are used to reduce body temperature in fever. (See all compounds classified as Antipyretics.)


API Reference Price

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Tower"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1728585000,"product":"FLUNIXIN MEGIUMINE (FREIGHT VALUE 5354.4 AS PER INVOICE)","address":"3RD FLOOR, NO.301, DOSTI PINNACLE","city":"ESTATE,DIST.THANE WEST, M.S.","supplier":"XXMEDXXMTCXXNIMXX HEXXTH XX.\/ XXNTEXXNIMXX INXX","supplierCountry":"CANADA","foreign_port":"TORONTO","customer":"ALIVIRA ANIMAL HEALTH","customerCountry":"INDIA","quantity":"500.00","actualQuantity":"500","unit":"KGS","unitRateFc":"180.7","totalValueFC":"91236.4","currency":"USD","unitRateINR":"15332.6","date":"11-Oct-2024","totalValueINR":"7666282","totalValueInUsd":"91236.4","indian_port":"Vizag-RPCIPL SEZ","hs_no":"29420090","bill_no":"1001355","productDescription":"API","marketType":"REGULATED MARKET","country":"CANADA","selfForZScoreResived":"Pharma Grade","supplierPort":"TORONTO","supplierAddress":"N\/A","customerAddress":"3RD FLOOR, NO.301, DOSTI PINNACLE"}]
19-Jan-2021
11-Oct-2024
KGS
overview
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Average Price (USD/KGS)

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country Total Quantity
(KGS)
Average Price
(USD/KGS)
Number of Transactions

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