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Chemistry

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Also known as: 42461-84-7, Flunixin meglumin, Banamine, Sch 14714 meglumine, Flumeglumine, Flunixin-s
Molecular Formula
C21H28F3N3O7
Molecular Weight
491.5  g/mol
InChI Key
MGCCHNLNRBULBU-WZTVWXICSA-N
FDA UNII
8Y3JK0JW3U

Flunixin Meglumine
1 2D Structure

Flunixin Meglumine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol;2-[2-methyl-3-(trifluoromethyl)anilino]pyridine-3-carboxylic acid
2.1.2 InChI
InChI=1S/C14H11F3N2O2.C7H17NO5/c1-8-10(14(15,16)17)5-2-6-11(8)19-12-9(13(20)21)4-3-7-18-12;1-8-2-4(10)6(12)7(13)5(11)3-9/h2-7H,1H3,(H,18,19)(H,20,21);4-13H,2-3H2,1H3/t;4-,5+,6+,7+/m.0/s1
2.1.3 InChI Key
MGCCHNLNRBULBU-WZTVWXICSA-N
2.1.4 Canonical SMILES
CC1=C(C=CC=C1NC2=C(C=CC=N2)C(=O)O)C(F)(F)F.CNCC(C(C(C(CO)O)O)O)O
2.1.5 Isomeric SMILES
CC1=C(C=CC=C1NC2=C(C=CC=N2)C(=O)O)C(F)(F)F.CNC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O
2.2 Other Identifiers
2.2.1 UNII
8Y3JK0JW3U
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Banamine

2. Finadyne

3. Sch 14714 Meglumine

2.3.2 Depositor-Supplied Synonyms

1. 42461-84-7

2. Flunixin Meglumin

3. Banamine

4. Sch 14714 Meglumine

5. Flumeglumine

6. Flunixin-s

7. Flunixin N-methylglucanine

8. Flunixin (meglumine)

9. Flunixin Meglumine Salt

10. Sch-14714 Meglumine

11. Nsc-759583

12. 8y3jk0jw3u

13. Finadyne

14. Chebi:76144

15. (2r,3r,4r,5s)-6-(methylamino)hexane-1,2,3,4,5-pentaol 2-((2-methyl-3-(trifluoromethyl)phenyl)amino)nicotinate

16. 1-deoxy-1-(methylamino)-d-glucitol 2-(2-methyl-3-(perfluoromethyl)anilino)nicotinate

17. 3-pyridinecarboxylic Acid, 2-((2-methyl-3-(trifluoromethyl)phenyl)amino)-, Compd. With 1-deoxy-1-(methylamino)-d-glucitol (1:1)

18. Banamine (veterinary)

19. Flunixin Meglumine [usan]

20. (2r,3r,4r,5s)-6-(methylamino)hexane-1,2,3,4,5-pentol;2-[2-methyl-3-(trifluoromethyl)anilino]pyridine-3-carboxylic Acid

21. Smr000875279

22. Sr-05000001901

23. Einecs 255-836-0

24. Unii-8y3jk0jw3u

25. Flunixin Meglumine [usan:usp]

26. Flunixin Meglumine (usp)

27. Banamine [vetarynary] (tn)

28. Schembl43691

29. Bspbio_002558

30. 2-(alpha(sup 3),alpha(sup 3),alpha(sup 3)-trifluoro-2,3-xylidino)nicotinic Acid Compound With 1-deoxy-1-(methylamino)-d-glucitol (1:1)

31. Mls001333159

32. Mls002153985

33. Spectrum1505113

34. Chembl1733447

35. Hms2093i10

36. Hms2234k05

37. Hms3884j07

38. Pharmakon1600-01505113

39. Flunixin Meglumine [mart.]

40. Flunixin Meglumine [usp-rs]

41. Hy-b0386

42. Flunixin Meglumine Salt [mi]

43. Mfcd01725419

44. Nsc759583

45. S2108

46. Flunixin Meglumine, >=98% (hplc)

47. Akos015895954

48. Ac-6012

49. Ccg-213338

50. Flunixin Meglumine [green Book]

51. Ks-5126

52. Nsc 759583

53. Ncgc00180889-01

54. 2-((2-methyl-3-(trifluoromethyl)-phenyl)amino)-3-pyridinecarboxylic Acid With Meglumine Compounded

55. D-glucitol, 1-deoxy-1-(methylamino)-, 2-((2-methyl-3-(trifluoromethyl)phenyl)amino)-3-pyridinecarboxylate (salt)

56. Flunixin Meglumine [usp Monograph]

57. Sw196448-3

58. Flunixin Meglumine 100 Microg/ml In Methanol

59. D04216

60. H10204

61. Ab00920714_05

62. Ab00920714_06

63. 461f847

64. Flunixin Meglumine 100 Microg/ml In Acetonitrile

65. Q-201124

66. Sr-05000001901-1

67. Sr-05000001901-3

68. Q27145782

69. Flunixin Meglumine, European Pharmacopoeia (ep) Reference Standard

70. Flunixin Meglumine, United States Pharmacopeia (usp) Reference Standard

71. Flunixin Meglumine, Pharmaceutical Secondary Standard; Certified Reference Material

72. (2r,3r,4r,5s)-6-(methylamino)hexane-1,2,3,4,5-pentaol 2-(2-methyl-3-(trifluoromethyl)phenylamino)nicotinate

73. (2r,3r,4r,5s)-6-(methylamino)hexane-1,2,3,4,5-pentaol2-((2-methyl-3-(trifluoromethyl)phenyl)amino)nicotinate

74. 1-deoxy-1-(methylazaniumyl)-d-glucitol 2-{[2-methyl-3-(trifluoromethyl)phenyl]amino}nicotinate

75. 2-(.alpha.(sup 3),.alpha.(sup 3),.alpha.(sup 3)-trifluoro-2,3-xylidino)nicotinic Acid Compound With 1-deoxy-1-(methylamino)-d-glucitol (1:1)

76. 2-{[2-methyl-3-(trifluoromethyl)phenyl]amino}nicotinic Acid--1-deoxy-1-(methylamino)-d-glucitol (1/1)

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 491.5 g/mol
Molecular Formula C21H28F3N3O7
Hydrogen Bond Donor Count8
Hydrogen Bond Acceptor Count13
Rotatable Bond Count9
Exact Mass491.18793473 g/mol
Monoisotopic Mass491.18793473 g/mol
Topological Polar Surface Area175 Ų
Heavy Atom Count34
Formal Charge0
Complexity510
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anti-Inflammatory Agents, Non-Steroidal

Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)


Antipyretics

Drugs that are used to reduce body temperature in fever. (See all compounds classified as Antipyretics.)


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DATTANI ,","city":"MUMBAI, BORIVALI WEST,MAHARASHTRA","supplier":"QILU PHARMACEUTICAL","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"SKIES","customerCountry":"INDIA","quantity":"625.00","actualQuantity":"625","unit":"KGS","unitRateFc":"102","totalValueFC":"64551.5","currency":"USD","unitRateINR":"7660.2","date":"09-Aug-2021","totalValueINR":"4787625","totalValueInUsd":"64551.5","indian_port":"JNPT","hs_no":"29333990","bill_no":"4981853","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"","customerAddress":"A-409, SENATE AURA BIPLEX, 4TH FLR. PLOT NO. 7, OPP. DATTANI ,"},{"dataSource":"API Import","activeIngredients":"","year":"2021","qtr":"Q3","strtotime":1630002600,"product":"FLUNIXIN MEGLUMINE EP\/IP (VET)","address":"A-409, SENATE AURA BIPLEX, 4TH FLR. PLOT NO. 7, OPP. DATTANI ,","city":"MUMBAI, BORIVALI WEST,MAHARASHTRA","supplier":"QILU PHARMACEUTICAL","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"SKIES","customerCountry":"INDIA","quantity":"250.00","actualQuantity":"250","unit":"KGS","unitRateFc":"102","totalValueFC":"25855","currency":"USD","unitRateINR":"7670.4","date":"27-Aug-2021","totalValueINR":"1917600","totalValueInUsd":"25855","indian_port":"JNPT","hs_no":"29333990","bill_no":"5208845","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"","customerAddress":"A-409, SENATE AURA BIPLEX, 4TH FLR. PLOT NO. 7, OPP. DATTANI ,"},{"dataSource":"API Import","activeIngredients":"","year":"2021","qtr":"Q4","strtotime":1633458600,"product":"FLUNIXIN MEGLUMINE","address":"215, MAHINDER CHAMBERS, W.T. PATIL ,MARG, CHEMBUR,","city":"MUMBAI,MAHARASHTRA","supplier":"ZHEJIANG HISOAR PHARMACEUTICAL","supplierCountry":"CHINA","foreign_port":"NA","customer":"HUFORT HEALTHCARE PRIVATE ","customerCountry":"INDIA","quantity":"312.97","actualQuantity":"312.97","unit":"KGS","unitRateFc":"136","totalValueFC":"42547.1","currency":"USD","unitRateINR":"10184","date":"06-Oct-2021","totalValueINR":"3187287.03","totalValueInUsd":"42547.1","indian_port":"JNPT","hs_no":"29339990","bill_no":"5729671","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"215, MAHINDER CHAMBERS, W.T. PATIL ,MARG, CHEMBUR,"},{"dataSource":"API Import","activeIngredients":"","year":"2021","qtr":"Q4","strtotime":1636482600,"product":"RE-IMPORT- FLUNIXIN MEGLUMINE BATCH ASA001151A","address":"3RD FLOOR NO 301 DOSTI PINNACLE,PL OT NO E-7 ROAD NO 22 WAGLE ESTATE","city":"THANE WEST,MAHARASHTRA","supplier":"FLAVINE","supplierCountry":"INDIA","foreign_port":"NA","customer":"ALIVIRA ANIMAL HEALTH","customerCountry":"INDIA","quantity":"275.00","actualQuantity":"275","unit":"KGS","unitRateFc":"172","totalValueFC":"47985.2","currency":"USD","unitRateINR":"12994.6","date":"10-Nov-2021","totalValueINR":"3573515","totalValueInUsd":"47985.2","indian_port":"JNPT","hs_no":"29420090","bill_no":"6196092","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"3RD FLOOR NO 301 DOSTI PINNACLE,PL OT NO E-7 ROAD NO 22 WAGLE ESTATE"},{"dataSource":"API 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PATIL ,MARG, CHEMBUR,","city":"MUMBAI,MAHARASHTRA","supplier":"ZHEJIANG HISOAR PHAMACEUTICAL SALES CO.,LTD.","supplierCountry":"CHINA","foreign_port":"NA","customer":"HUFORT HEALTHCARE PRIVATE ","customerCountry":"INDIA","quantity":"231.66","actualQuantity":"231.66","unit":"KGS","unitRateFc":"106","totalValueFC":"24635.3","currency":"USD","unitRateINR":"8522.4","date":"22-Sep-2022","totalValueINR":"1974299.18","totalValueInUsd":"24635.3","indian_port":"BOMBAY AIR","hs_no":"29339990","bill_no":"2557114","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"215, MAHINDER CHAMBERS, W.T. PATIL ,MARG, CHEMBUR,"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q3","strtotime":1664389800,"product":"FLUNIXIN MEGLUMINE EP\/IP (VET)","address":"1101, 11TH FLOOR, DHUKKA CHAMBERS OFF PODDAR PARK ROAD, MALAD EAST","city":"MUMBAI","supplier":"QILU PHARMACEUTICAL","supplierCountry":"CHINA","foreign_port":"NA","customer":"UNICHEMIE INTERNATIONAL PRIVATE LIMITED","customerCountry":"INDIA","quantity":"600.00","actualQuantity":"600","unit":"KGS","unitRateFc":"110","totalValueFC":"66213.3","currency":"USD","unitRateINR":"8844","date":"29-Sep-2022","totalValueINR":"5306400","totalValueInUsd":"66213.3","indian_port":"BOMBAY AIR","hs_no":"29333990","bill_no":"2664585","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"1101, 11TH FLOOR, DHUKKA CHAMBERS OFF PODDAR PARK ROAD, MALAD EAST"},{"dataSource":"API 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DOSTI PINNACLE","city":"ESTATE,DIST.THANE WEST, M.S.","supplier":"DECHRA PHARMACEUTICALS MANUFACTURING","supplierCountry":"NETHERLANDS","foreign_port":"AMSTERDAM","customer":"ALIVIRA ANIMAL HEALTH","customerCountry":"INDIA","quantity":"100.00","actualQuantity":"100","unit":"KGS","unitRateFc":"200","totalValueFC":"20169.6","currency":"USD","unitRateINR":"16860","date":"04-Jul-2024","totalValueINR":"1686000","totalValueInUsd":"20169.6","indian_port":"Vizag-RPCIPL SEZ","hs_no":"29420090","bill_no":"1001072","productDescription":"API","marketType":"REGULATED MARKET","country":"NETHERLANDS","selfForZScoreResived":"Pharma Grade","supplierPort":"AMSTERDAM","supplierAddress":"N\/A","customerAddress":"3RD FLOOR, NO.301, DOSTI PINNACLE"}]
05-Feb-2021
04-Jul-2024
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ABOUT THIS PAGE

Flunixin Meglumine Manufacturers

A Flunixin Meglumine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Flunixin Meglumine, including repackagers and relabelers. The FDA regulates Flunixin Meglumine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Flunixin Meglumine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Flunixin Meglumine manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Flunixin Meglumine Suppliers

A Flunixin Meglumine supplier is an individual or a company that provides Flunixin Meglumine active pharmaceutical ingredient (API) or Flunixin Meglumine finished formulations upon request. The Flunixin Meglumine suppliers may include Flunixin Meglumine API manufacturers, exporters, distributors and traders.

click here to find a list of Flunixin Meglumine suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Flunixin Meglumine USDMF

A Flunixin Meglumine DMF (Drug Master File) is a document detailing the whole manufacturing process of Flunixin Meglumine active pharmaceutical ingredient (API) in detail. Different forms of Flunixin Meglumine DMFs exist exist since differing nations have different regulations, such as Flunixin Meglumine USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Flunixin Meglumine DMF submitted to regulatory agencies in the US is known as a USDMF. Flunixin Meglumine USDMF includes data on Flunixin Meglumine's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Flunixin Meglumine USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Flunixin Meglumine suppliers with USDMF on PharmaCompass.

Flunixin Meglumine CEP

A Flunixin Meglumine CEP of the European Pharmacopoeia monograph is often referred to as a Flunixin Meglumine Certificate of Suitability (COS). The purpose of a Flunixin Meglumine CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Flunixin Meglumine EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Flunixin Meglumine to their clients by showing that a Flunixin Meglumine CEP has been issued for it. The manufacturer submits a Flunixin Meglumine CEP (COS) as part of the market authorization procedure, and it takes on the role of a Flunixin Meglumine CEP holder for the record. Additionally, the data presented in the Flunixin Meglumine CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Flunixin Meglumine DMF.

A Flunixin Meglumine CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Flunixin Meglumine CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

click here to find a list of Flunixin Meglumine suppliers with CEP (COS) on PharmaCompass.

Flunixin Meglumine NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Flunixin Meglumine as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Flunixin Meglumine API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Flunixin Meglumine as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Flunixin Meglumine and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Flunixin Meglumine NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Flunixin Meglumine suppliers with NDC on PharmaCompass.

Flunixin Meglumine GMP

Flunixin Meglumine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Flunixin Meglumine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Flunixin Meglumine GMP manufacturer or Flunixin Meglumine GMP API supplier for your needs.

Flunixin Meglumine CoA

A Flunixin Meglumine CoA (Certificate of Analysis) is a formal document that attests to Flunixin Meglumine's compliance with Flunixin Meglumine specifications and serves as a tool for batch-level quality control.

Flunixin Meglumine CoA mostly includes findings from lab analyses of a specific batch. For each Flunixin Meglumine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Flunixin Meglumine may be tested according to a variety of international standards, such as European Pharmacopoeia (Flunixin Meglumine EP), Flunixin Meglumine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Flunixin Meglumine USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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