Find Flunixin manufacturers, exporters & distributors on PharmaCompass

Flunixin

Synopsis, Chemistry

APIs // Active Pharmaceutical Ingredients

1 API Suppliers, 1 Listed Suppliers

PRICE INFORMATION

API Reference Price, API Exports, API Imports

DOSSIERs // Finished Dosage Formulations

1 Dossiers, 1 Listed Dossiers

REF. STANDARDS & IMPURITIES

3 Others

3 Others

API SUPPLIERS

API Suppliers

US DMFs Filed

CEP/COS Certifications

JDMFs Filed

EU WC

Listed Suppliers

API REF. PRICE (USD / KG)

167

API Market Place

INTERMEDIATES

DOSSIERS // FDF

USA (Orange Book)

Europe

Canada

Australia

South Africa

Uploaded Dossiers

GLOBAL SALES (USD Million)

U.S. Medicaid

Annual Reports

FDF Market Place

EXCIPIENTS

PATENTS & EXCLUSIVITIES

USFDA Orange Book Patents

USFDA Exclusivities

DIGITAL CONTENT

Blog #PharmaFlow

News

REF STANDARD

EDQM

USP

Other Listed Suppliers

SERVICES

Also known as: 38677-85-9, Flunixine, Sch 14714, Flunixino, Flunixinum, Sch-14714

Molecular Formula

C₁₄H₁₁F₃N₂O₂

Molecular Weight

296.24 g/mol

InChI Key

NOOCSNJCXJYGPE-UHFFFAOYSA-N

FDA UNII

356IB1O400

Flunixin is a non-steroidal anti-inflammatory drug for use in pigs, cattle and horses. It exerts analgesic and antipyretic effects. This drug is often prepared for use in meglumine salt form. Flunixin is regulated in the United States by the Food and Drug Administration (FDA) and must be prescribed by a licensed veterinarian. Flunixin may be also referred to as Banamine, and other trade names.

1 2D Structure

Flunixin

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

2-[2-methyl-3-(trifluoromethyl)anilino]pyridine-3-carboxylic acid

2.1.2 InChI

InChI=1S/C14H11F3N2O2/c1-8-10(14(15,16)17)5-2-6-11(8)19-12-9(13(20)21)4-3-7-18-12/h2-7H,1H3,(H,18,19)(H,20,21)

2.1.3 InChI Key

NOOCSNJCXJYGPE-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CC1=C(C=CC=C1NC2=C(C=CC=N2)C(=O)O)C(F)(F)F

2.2 Other Identifiers

2.2.1 UNII

356IB1O400

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Sch 14714

2.3.2 Depositor-Supplied Synonyms

1. 38677-85-9

2. Flunixine

3. Sch 14714

4. Flunixino

5. Flunixinum

6. Sch-14714

7. 2-((2-methyl-3-(trifluoromethyl)phenyl)amino)nicotinic Acid

8. Chebi:76138

9. 2-{[2-methyl-3-(trifluoromethyl)phenyl]amino}nicotinic Acid

10. 2-[2-methyl-3-(trifluoromethyl)anilino]pyridine-3-carboxylic Acid

11. 356ib1o400

12. 2-[[2-methyl-3-(trifluoromethyl)phenyl]amino]pyridine-3-carboxylic Acid

13. 3-pyridinecarboxylic Acid, 2-((2-methyl-3-(trifluoromethyl)phenyl)amino)-

14. Flunixin [usan]

15. Flunixine [inn-french]

16. Flunixinum [inn-latin]

17. Flunixino [inn-spanish]

18. 2-((2-methyl-3-(trifluoromethyl)phenyl)amino)-3-pyridinecarboxylic Acid

19. 2-[[2-methyl-3-(trifluoromethyl)phenyl]amino]-3-pyridinecarboxylic Acid

20. 3-pyridinecarboxylic Acid, 2-[[2-methyl-3-(trifluoromethyl)phenyl]amino]-

21. Flunixin [usan:inn:ban]

22. Flunixin-meglumin

23. Unii-356ib1o400

24. 2(2'-methyl-3'-trifluoromethylanilino)nicotinic Acid

25. Flunixin (usan/inn)

26. Flunixin [inn]

27. Flunixin [mi]

28. 2-(alpha(sup 3),alpha(sup 3),alpha(sup 3)-trifluoro-2,3-xylidino)nicotinic Acid

29. Schembl42911

30. Mls004712071

31. Flunixin [green Book]

32. Sch14714

33. Zinc1467

34. Chembl1617398

35. Dtxsid4048565

36. 2-[2-methyl-3-(trifluoromethyl)phenylamino]nicotinic Acid

37. Bcp12991

38. Bdbm50201618

39. Mfcd00072033

40. Akos015963218

41. Ac-1265

42. Db11518

43. Flunixin 100 Microg/ml In Acetonitrile

44. Smr000857255

45. Ft-0626444

46. Flunixin, Vetranal(tm), Analytical Standard

47. Vu0244596-2

48. D04215

49. 677f859

50. Q906934

51. Sr-01000883753

52. Sr-01000883753-1

53. 2-(2-methyl-3-trifluoromethylanilino) Nicotinic Acid

54. Brd-k99984802-098-03-2

55. Brd-k99984802-100-01-0

56. Brd-k99984802-100-06-9

57. 2-(alpha(3),alpha(3),alpha(3)-trifluoro-2,3-xylidino)nicotinic Acid

58. 2-(.alpha.(sup 3),.alpha.(sup 3),.alpha.(sup 3)-trifluoro-2,3-xylidino)nicotinic Acid.

59. Jbo

2.4 Create Date

2005-08-08

3 Chemical and Physical Properties

Molecular Formula	C₁₄H₁₁F₃N₂O₂
Molecular Weight	296.24 g/mol
XLogP3	4.1
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	3
Exact Mass	296.07726208 g/mol
Monoisotopic Mass	296.07726208 g/mol
Topological Polar Surface Area	62.2 Å²
Heavy Atom Count	21
Formal Charge	0
Complexity	376
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Anti-Inflammatory Agents, Non-Steroidal

Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)

Antipyretics

Drugs that are used to reduce body temperature in fever. (See all compounds classified as Antipyretics.)