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1. (18)f-dopa
2. 18f-fdopa
3. 2-fluoro-5-hydroxytyrosine
4. 3,4-dihydroxy-6-fluorophenylalanine
5. 3-(2-fluoro-(18)f-4,5-dihydroxyphenyl)-l-alanine
6. 6-(18f)fluoro-l-3,4-dihydroxyphenylalanine
7. 6-(18f)fluoro-l-dopa
8. 6-fluoro-dopa
9. 6-fluorodopa
10. Fluorodopa
11. Fluorodopa F 18
12. Fluorodopa F 18, (18)f-labeled Cpd
13. Fluorodopa F-18
1. Fluorodopa F 18
2. Fluorodopa F18
3. Fluorodopa F-18
4. 92812-82-3
5. 18f-dopa
6. L-6-(18f)fluoro-dopa
7. Fluorine-18-fluoro-l-dopa
8. 18f-l-fluoro-dopa
9. Fdopa F-18
10. Fluorodopa (18f) [inn]
11. Chebi:49166
12. 2c598205qx
13. L-tyrosine, 2-(fluoro-18f)-5-hydroxy-
14. (s)-2-amino-3-(2-(fluoro-18f)-4,5-dihydroxyphenyl)propanoic Acid
15. Fluorodopa F 18 (usan)
16. Fluorodopa F 18 [usan]
17. F-dopa
18. (18f)fdopa
19. 6-(18f)fluoro-l-dopa
20. 2-(fluoro-18f)-l-dopa
21. Unii-2c598205qx
22. Fluorodopa-f-18
23. Fluorodopa F 18 [usan:usp:inn]
24. 2-(fluoro-18f)-5-hydroxy-l-tyrosine
25. Fluorodopa ((18)f)
26. Fluorodopa F18 (tn)
27. Schembl522323
28. Fluorodopa F18 [mi]
29. ((18)f)fdopa
30. 6-((18)f)fluoro-l-dopa
31. Chembl3400972
32. L-6-((18)f)fluoro-dopa
33. Dtxsid60239157
34. Moli000246
35. Moli000965
36. Fluorodopa (18f) [who-dd]
37. Db13848
38. Fluorodopa F-18 [orange Book]
39. 18f-fluoro-dihydroxyphenylalanine
40. Fluorodopa F 18 [usp Impurity]
41. 2-((18)f)fluoro-5-hydroxy-l-tyrosine
42. 2-(fluoro-(18)f)-5-hydroxy-l-tyrosine
43. D04220
44. L-tyrosine, 2-(fluoro-(sup 18)f)-5-hydroxy-
45. 6-((18)f)fluoro-3,4-dihydroxy-l-phenylalanine
46. L-3,4-dihydroxy-6-(18f)fluorophenylalanine
47. 3-(2-fluoro-(18)f-4,5-dihydroxyphenyl)-l-alanine
48. 6-fluoro-(18f)-l-3,4-dihydroxyphenylalanine
49. Q27121509
50. (18f)-6-fluoro-l,3,4, Dihydroxyphenylalanine
51. 3-(2-fluoro-(sup 18)f-4,5-dihydroxyphenyl)-l-alanine
52. (2s)-2-amino-3-(2-(18f)fluoranyl-4,5-dihydroxyphenyl)propanoic Acid
53. (2s)-2-amino-3-[2-((18)f)fluoro-4,5-dihydroxyphenyl]propanoic Acid
| Molecular Weight | 214.18 g/mol |
|---|---|
| Molecular Formula | C9H10FNO4 |
| XLogP3 | -2 |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 3 |
| Exact Mass | 214.061920 g/mol |
| Monoisotopic Mass | 214.061920 g/mol |
| Topological Polar Surface Area | 104 Ų |
| Heavy Atom Count | 15 |
| Formal Charge | 0 |
| Complexity | 238 |
| Isotope Atom Count | 1 |
| Defined Atom Stereocenter Count | 1 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
Fluorodopa F 18 is indicated for use with positron emission tomography (PET) to visualize dopaminergic nerve terminals in the striatum for the evaluation of adult patients with suspected Parkinsonian syndromes (PS).
V - Various
V09 - Diagnostic radiopharmaceuticals
V09I - Tumour detection
V09IX - Other diagnostic radiopharmaceuticals for tumour detection
V09IX05 - Fluorodopa (18F)
Route of Elimination
Approximately 80% of the administered radioactivity is eliminated in the urine.
Clearance
The agent is cleared from blood and tissue within 24 hours following administration.
Fluorodopa F 18 is decarboxylated by aromatic amino acid decarboxylase (AADC) in the striatum to fluorodopamine F 18. Fluorodopamine F 18 is then further metabolized by monoamine oxidase (MAO) to yield [18F] 6-fluoro-3,4-dihydroxyphenylacetic acid, then subsequently by COMT to yield [18F]6-fluorohomovanillic acid.
The plasma half-life following intravenous administration is approximately 1-3 hours.
Patents & EXCLUSIVITIES
ABOUT THIS PAGE
A fluorodopa-f-18 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of fluorodopa-f-18, including repackagers and relabelers. The FDA regulates fluorodopa-f-18 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. fluorodopa-f-18 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
A fluorodopa-f-18 supplier is an individual or a company that provides fluorodopa-f-18 active pharmaceutical ingredient (API) or fluorodopa-f-18 finished formulations upon request. The fluorodopa-f-18 suppliers may include fluorodopa-f-18 API manufacturers, exporters, distributors and traders.
click here to find a list of fluorodopa-f-18 suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.
A fluorodopa-f-18 DMF (Drug Master File) is a document detailing the whole manufacturing process of fluorodopa-f-18 active pharmaceutical ingredient (API) in detail. Different forms of fluorodopa-f-18 DMFs exist exist since differing nations have different regulations, such as fluorodopa-f-18 USDMF, ASMF (EDMF), JDMF, CDMF, etc.
A fluorodopa-f-18 DMF submitted to regulatory agencies in the US is known as a USDMF. fluorodopa-f-18 USDMF includes data on fluorodopa-f-18's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The fluorodopa-f-18 USDMF is kept confidential to protect the manufacturer’s intellectual property.
click here to find a list of fluorodopa-f-18 suppliers with USDMF on PharmaCompass.
fluorodopa-f-18 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of fluorodopa-f-18 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right fluorodopa-f-18 GMP manufacturer or fluorodopa-f-18 GMP API supplier for your needs.
A fluorodopa-f-18 CoA (Certificate of Analysis) is a formal document that attests to fluorodopa-f-18's compliance with fluorodopa-f-18 specifications and serves as a tool for batch-level quality control.
fluorodopa-f-18 CoA mostly includes findings from lab analyses of a specific batch. For each fluorodopa-f-18 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
fluorodopa-f-18 may be tested according to a variety of international standards, such as European Pharmacopoeia (fluorodopa-f-18 EP), fluorodopa-f-18 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (fluorodopa-f-18 USP).
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