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Symbiotec Fluorometholone

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Valsynthese, part of the SSE Group, is a CDMO focused on highly energetic and highly hazardous chemistry.

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Fluorometholone RMB

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Bloomage is a one-stop source for CEP Sodium Hyaluronate and Hyaluronic Acid// FDA-inspected & GMP-certified.

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CHEMISTRY
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ACTIVE PHARMA INGREDIENTS

16 API Suppliers, 7 USDMF, 3 JDMF, 4 KDMF, 6 NDC API, 12 Listed Suppliers, $ API Reference Price

16 API Suppliers
7 USDMF
3 JDMF
4 KDMF
6 NDC API
12 Listed Suppliers
$ API Reference Price

DEVELOPMENTS

1 Drugs in Development

1 Drugs in Development

FINISHED DOSAGE FORMULATIONS

38 FDF Dossiers, 7 FDA Orange Book, 12 Europe, 3 Canada, 3 South Africa, 13 Listed Dossiers

38 FDF Dossiers
7 FDA Orange Book
12 Europe
3 Canada
3 South Africa
13 Listed Dossiers

DRUG PRODUCT COMPOSITIONS

SUSPENSION/DROPS;OPHTHALMIC - 0.1%, OINTMENT;OPHTHALMIC - 0.1%

drugProductComposition
SUSPENSION/DROPS;OPHTHALMIC - 0.1%
OINTMENT;OPHTHALMIC - 0.1%

RELATED EXCIPIENT COMPANIES

1 DKSH, 1 Nanjing Well Pharmaceutical, 6 Actylis, 2 BASF, 5 Corel Pharma Chem, 1 Finar, 4 Gangwal Chemicals, 2 Ideal Cures Pvt Ltd, 3 Kerry, 1 Nanjing Bold Chemical, 1 Novo Excipients, 6 Seppic

relatedExcipients
1 DKSH
1 Nanjing Well Pharmaceutical
6 Actylis
2 BASF
5 Corel Pharma Chem
1 Finar
4 Gangwal Chemicals
2 Ideal Cures Pvt Ltd
3 Kerry
1 Nanjing Bold Chemical
1 Novo Excipients
6 Seppic

EXCIPIENTS BY APPLICATIONS

13 Solubilizers, 12 Coating Systems & Additives, 9 Parenteral, 5 Topical, 4 Controlled & Modified Release, 3 Emulsifying Agents, 2 Surfactant & Foaming Agents, 2 Thickeners and Stabilizers, 2 API Stability Enhancers, 2 Film Formers & Plasticizers, 1 Direct Compression, 1 Rheology Modifiers, 1 Co-Processed Excipients, 1 Fillers, Diluents & Binders, 1 Disintegrants & Superdisintegrants

excipientsByApplications
13 Solubilizers
12 Coating Systems & Additives
9 Parenteral
5 Topical
4 Controlled & Modified Release
3 Emulsifying Agents
2 Surfactant & Foaming Agents
2 Thickeners and Stabilizers
2 API Stability Enhancers
2 Film Formers & Plasticizers
1 Direct Compression
1 Rheology Modifiers
1 Co-Processed Excipients
1 Fillers, Diluents & Binders
1 Disintegrants & Superdisintegrants

DIGITAL CONTENT

1 DATA COMPILATION #PharmaFlow, 3 NEWS #PharmaBuzz

media
1 DATA COMPILATION #PharmaFlow
3 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

4 US Medicaid Prescriptions, 13 Finished Drug Prices

globalSalesInformation
4 US Medicaid Prescriptions
13 Finished Drug Prices

MARKET PLACE

11 APIs, 1 FDF Dossiers

marketPlace
11 APIs
1 FDF Dossiers

PATENTS & EXCLUSIVITIES

1 US Exclusivities

patents
1 US Exclusivities

REF. STANDARDS & IMPURITIES

2 USP , 2 JP , 2 Others

otherSolutions
2 USP
2 JP
2 Others

Symbiotec Fluorometholone

Synopsis

ACTIVE PHARMA INGREDIENTS

16

API Suppliers

7

USDMF

0

CEP/COS

CEP/COS Certifications

3

JDMF

0

EU WC

4

KDMF

6

NDC API

0

VMF

12

Listed Suppliers

API REF. PRICE (USD/KG)

$

$ 9,530

MARKET PLACE

11

API

1

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

38

FDF Dossiers

7

FDA Orange Book

FDA (Orange Book)

12

Europe

3

Canada

0

Australia

3

South Africa

13

Listed Dossiers

1DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

0

EDQM

2

USP

2

JP

2

Others

PATENTS & EXCLUSIVITIES

0

US Patents

1

US Exclusivities

0

Health Canada Patents

DIGITAL CONTENT

1

Data Compilation #PharmaFlow

0

Stock Recap #PipelineProspector

0

Weekly News Recap #Phispers

3

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

27,973,018

Annual Reports (USD Million)

NA

Finished Drug Prices

33 RELATED EXCIPIENT COMPANIES

59EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: 426-13-1, Fluoromethalone, Oxylone, Flumetholon, Fluor-op, Fluormetholone

Molecular Formula

C₂₂H₂₉FO₄

Molecular Weight

376.5 g/mol

InChI Key

FAOZLTXFLGPHNG-KNAQIMQKSA-N

FDA UNII

SV0CSG527L

Fluorometholone

A glucocorticoid employed, usually as eye drops, in the treatment of allergic and inflammatory conditions of the eye. It has also been used topically in the treatment of various skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p732)

Fluorometholone is a Corticosteroid. The mechanism of action of fluorometholone is as a Corticosteroid Hormone Receptor Agonist.

1 2D Structure

Fluorometholone

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(6S,8S,9R,10S,11S,13S,14S,17R)-17-acetyl-9-fluoro-11,17-dihydroxy-6,10,13-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one

2.1.2 InChI

InChI=1S/C22H29FO4/c1-12-9-17-15-6-8-21(27,13(2)24)20(15,4)11-18(26)22(17,23)19(3)7-5-14(25)10-16(12)19/h5,7,10,12,15,17-18,26-27H,6,8-9,11H2,1-4H3/t12-,15-,17-,18-,19-,20-,21-,22-/m0/s1

2.1.3 InChI Key

FAOZLTXFLGPHNG-KNAQIMQKSA-N

2.1.4 Canonical SMILES

CC1CC2C3CCC(C3(CC(C2(C4(C1=CC(=O)C=C4)C)F)O)C)(C(=O)C)O

2.1.5 Isomeric SMILES

C[C@H]1C[C@H]2[C@@H]3CC[C@@]([C@]3(C[C@@H]([C@@]2([C@@]4(C1=CC(=O)C=C4)C)F)O)C)(C(=O)C)O

2.2 Other Identifiers

2.2.1 UNII

SV0CSG527L

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Cortisdin

2. Efflumidex

3. Flucon

4. Flucon, Isopto

5. Fluor Op

6. Fluor-op

7. Fluoro Ophtal

8. Fluoro-ophtal

9. Fluoropos

10. Fml

11. Fml Forte

12. Fml Liquifilm

13. Isopto Flucon

14. Pms Fluorometholone

15. Pms-fluorometholone

2.3.2 Depositor-Supplied Synonyms

1. 426-13-1

2. Fluoromethalone

3. Oxylone

4. Flumetholon

5. Fluor-op

6. Fluormetholone

7. Cortilet

8. Delmeson

9. Fml Liquifilm

10. Trilcin

11. Fml Forte

12. Fluorometolona

13. Fluorometholonum

14. Fluormetholon

15. Nsc 33001

16. Fml

17. Component Of Neo-oxylone

18. U 8614

19. Chebi:31625

20. 9-fluoro-11beta,17-dihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione

21. Nsc-33001

22. (6s,8s,9r,10s,11s,13s,14s,17r)-17-acetyl-9-fluoro-11,17-dihydroxy-6,10,13-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one

23. Sv0csg527l

24. Mls000069537

25. Mls001076157

26. Fluormetholonum

27. 9-fluoro-11,17-dihydroxy-6-methylpregna-1,4-diene-3,20-dione

28. Nsc33001

29. Fluorometolone

30. Smr000058598

31. Fluorometolone [dcit]

32. Neo-oxylone

33. Fml-s Liquifilm

34. Dsstox_cid_27435

35. Dsstox_rid_82345

36. Fml S.o.p.

37. Dsstox_gsid_47435

38. Fluorometholonum [inn-latin]

39. Fluorometolona [inn-spanish]

40. Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-6-methyl-, (6.alpha.,11.beta.)-

41. Oxylone (tn)

42. Fluor-op (tn)

43. Fml (tn)

44. Einecs 207-041-5

45. Unii-sv0csg527l

46. Fluorometholon

47. Ai3-52813

48. Ncgc00016442-01

49. Cas-426-13-1

50. Prestwick_227

51. 9-fluoro-11-beta,17-dihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione

52. Fluorometholone [usp:inn:ban:jan]

53. Mfcd00056461

54. Opera_id_341

55. Prestwick0_000718

56. Prestwick1_000718

57. Prestwick2_000718

58. Prestwick3_000718

59. F0414

60. 11beta,17alpha-dihydroxy-9-fluoro-6-methyl-1,4-pregnadiene-3,20-dione

61. Fluorometholone, >=98%

62. Pregna-1,4-diene-3,20-dione, 9-fluoro-11-beta,17-dihydroxy-6-alpha-methyl-

63. Schembl5051

64. Fluorometholone [mi]

65. Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-6-methyl-, (6alpha,11beta)-

66. Bspbio_000935

67. Fluorometholone [inn]

68. Fluorometholone [jan]

69. Spbio_002856

70. Fluorometholone [vandf]

71. Bpbio1_001029

72. Gtpl7079

73. Fluorometholone [mart.]

74. Chembl1200600

75. Dtxsid7047435

76. Fluorometholone [usp-rs]

77. Fluorometholone [who-dd]

78. 9-fluoro-11.beta.,17-dihydroxy-6.alpha.-methylpregna-1,4-diene-3,20-dione

79. Pregna-1,4-diene-3,20-dione, 9-fluoro-11.beta.,17-dihydroxy-6.alpha.-methyl-

80. Fluorometholone (jp17/usp/inn)

81. Hms1570o17

82. Hms2097o17

83. Hms2234f16

84. Hms3714o17

85. Hy-b1893

86. Tox21_110440

87. Tox21_302593

88. Bdbm50103631

89. Fluorometholone [orange Book]

90. S5486

91. Akos015895108

92. Fml-s Component Fluorometholone

93. Pregna-1,4-diene-3,20-dione, 9-fluoro-11beta,17-dihydroxy-6alpha-methyl-

94. Tox21_110440_1

95. Zinc118912517

96. Ac-3520

97. Ccg-220718

98. Db00324

99. Fluorometholone [usp Monograph]

100. (6alpha,11beta)-9-fluoro-11,17-dihydroxy-6-methylpregna-1,4-diene-3,20-dione

101. Ncgc00021575-03

102. Ncgc00021575-05

103. Ncgc00256631-01

104. As-12363

105. Fluorometholone Component Of Fml-s

106. Nci60_002886

107. Cs-0013955

108. Progesterone, 17-dihydroxy-6.alpha.-methyl-

109. D01367

110. 426f131

111. Q607349

112. Sr-01000003019

113. Sr-01000003019-2

114. Brd-k64862097-001-03-9

115. Brd-k64862097-001-12-0

116. Fluorometholone, British Pharmacopoeia (bp) Reference Standard

117. Fluorometholone, United States Pharmacopeia (usp) Reference Standard

118. Pregna-1,20-dione, 9-fluoro-11.beta.,17-dihydroxy-6.alpha.-methyl-

119. Progesterone, 1-dehydro-9-fluoro-11.beta., 17-dihydroxy-6.alpha.-methyl-

120. Pregna-1,20-dione, 9-fluoro-11,17-dihydroxy-6-methyl-, (6.alpha.,11.beta.)-

121. Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-6-methyl-, (6i+/-,11i(2))-

122. (1r,2s,8s,10s,11s,14r,15s,17s)-14-acetyl-1-fluoro-14,17-dihydroxy-2,8,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one

123. (1r,2s,8s,10s,11s,14r,15s,17s)-14-acetyl-1-fluoro-14,17-dihydroxy-2,8,15-trimethyltetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-5-one

124. Pregna-1, 4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-6-methyl-, (6.alpha., 11.beta.)-

2.4 Create Date

2005-03-26

3 Chemical and Physical Properties

Molecular Formula	C₂₂H₂₉FO₄
Molecular Weight	376.5 g/mol
XLogP3	2
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	1
Exact Mass	376.20498756 g/mol
Monoisotopic Mass	376.20498756 g/mol
Topological Polar Surface Area	74.6 Å²
Heavy Atom Count	27
Formal Charge	0
Complexity	787
Isotope Atom Count	0
Defined Atom Stereocenter Count	8
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Drug and Medication Information

4.1 Drug Information

1 of 4
Drug Name	Fml
PubMed Health	Fluorometholone (Into the eye)
Drug Classes	Ophthalmologic Agent
Drug Label	FML (fluorometholone ophthalmic ointment) 0.1% is a sterile, topical anti-inflammatory agent for ophthalmic use....
Active Ingredient	Fluorometholone
Dosage Form	Ointment; Suspension/drops
Route	Ophthalmic
Strength	0.1%
Market Status	Prescription
Company	Allergan

2 of 4
Drug Name	Fml forte
PubMed Health	Fluorometholone (Into the eye)
Drug Classes	Ophthalmologic Agent
Drug Label	FML FORTE (fluorometholone ophthalmic suspension, USP) 0.25% is a sterile, topical anti-inflammatory agent for ophthalmic use. Chemical NameFluorometholone: 9-Fluoro-11, 17-dihydroxy-6-methylpregna-1,4-diene-3,20-dione. Structural FormulaContai...
Active Ingredient	Fluorometholone
Dosage Form	Suspension/drops
Route	Ophthalmic
Strength	0.25%
Market Status	Prescription
Company	Allergan

3 of 4
Drug Name	Fml
PubMed Health	Fluorometholone (Into the eye)
Drug Classes	Ophthalmologic Agent
Drug Label	FML (fluorometholone ophthalmic ointment) 0.1% is a sterile, topical anti-inflammatory agent for ophthalmic use....
Active Ingredient	Fluorometholone
Dosage Form	Ointment; Suspension/drops
Route	Ophthalmic
Strength	0.1%
Market Status	Prescription
Company	Allergan

4 of 4
Drug Name	Fml forte
PubMed Health	Fluorometholone (Into the eye)
Drug Classes	Ophthalmologic Agent
Drug Label	FML FORTE (fluorometholone ophthalmic suspension, USP) 0.25% is a sterile, topical anti-inflammatory agent for ophthalmic use. Chemical NameFluorometholone: 9-Fluoro-11, 17-dihydroxy-6-methylpregna-1,4-diene-3,20-dione. Structural FormulaContai...
Active Ingredient	Fluorometholone
Dosage Form	Suspension/drops
Route	Ophthalmic
Strength	0.25%
Market Status	Prescription
Company	Allergan

4.2 Drug Indication

For the ophthalmic treatment of corticosteroid-responsive inflammation of the palpebral and bulbar conjunctiva, cornea and anterior segment of the globe.

FDA Label

5 Pharmacology and Biochemistry

5.1 Pharmacology

Corticosteroids such as fluorometholone inhibit the inflammatory response to a variety of inciting agents and probably delay or slow healing. They inhibit the edema, fibrin deposition, capillary dilation, leukocyte migration, capillary proliferation, fibroblast proliferation, deposition of collagen, and scar formation associated with inflammation.

5.2 MeSH Pharmacological Classification

Anti-Inflammatory Agents

Substances that reduce or suppress INFLAMMATION. (See all compounds classified as Anti-Inflammatory Agents.)

Glucocorticoids

A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system. (See all compounds classified as Glucocorticoids.)

Anti-Allergic Agents

Agents that are used to treat allergic reactions. Most of these drugs act by preventing the release of inflammatory mediators or inhibiting the actions of released mediators on their target cells. (From AMA Drug Evaluations Annual, 1994, p475) (See all compounds classified as Anti-Allergic Agents.)

5.3 FDA Pharmacological Classification

5.3.1 Active Moiety

FLUOROMETHOLONE

5.3.2 FDA UNII

SV0CSG527L

5.3.3 Pharmacological Classes

Corticosteroid [EPC]; Corticosteroid Hormone Receptor Agonists [MoA]

5.4 ATC Code

S01BA07

S76 | LUXPHARMA | Pharmaceuticals Marketed in Luxembourg | Pharmaceuticals marketed in Luxembourg, as published by d'Gesondheetskeess (CNS, la caisse nationale de sante, www.cns.lu), mapped by name to structures using CompTox by R. Singh et al. (in prep.). List downloaded from https://cns.public.lu/en/legislations/textes-coordonnes/liste-med-comm.html. Dataset DOI:10.5281/zenodo.4587355

C - Cardiovascular system

C05 - Vasoprotectives

C05A - Agents for treatment of hemorrhoids and anal fissures for topical use

C05AA - Corticosteroids

C05AA06 - Fluorometholone

D - Dermatologicals

D07 - Corticosteroids, dermatological preparations

D07A - Corticosteroids, plain

D07AB - Corticosteroids, moderately potent (group ii)

D07AB06 - Fluorometholone

D - Dermatologicals

D07 - Corticosteroids, dermatological preparations

D07X - Corticosteroids, other combinations

D07XB - Corticosteroids, moderately potent, other combinations

D07XB04 - Fluorometholone

D - Dermatologicals

D10 - Anti-acne preparations

D10A - Anti-acne preparations for topical use

D10AA - Corticosteroids, combinations for treatment of acne

D10AA01 - Fluorometholone

S - Sensory organs

S01 - Ophthalmologicals

S01B - Antiinflammatory agents

S01BA - Corticosteroids, plain

S01BA07 - Fluorometholone

S - Sensory organs

S01 - Ophthalmologicals

S01C - Antiinflammatory agents and antiinfectives in combination

S01CB - Corticosteroids/antiinfectives/mydriatics in combination

S01CB05 - Fluorometholone

5.5 Mechanism of Action

There is no generally accepted explanation for the mechanism of action of ocular corticosteroids. However, corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor, arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2. Their primary target is the cytosolic glucocorticoid receptor. After binding the receptor the newly formed receptor-ligand complex translocates itself into the cell nucleus, where it binds to many glucocorticoid response elements (GRE) in the promoter region of the target genes. The DNA bound receptor then interacts with basic transcription factors, causing the increase in expression of specific target genes.

API SUPPLIERS

01

Symbiotec Pharmalab

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Henan Lihua Pharmaceutical

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Farmabios Spa

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Rev. Date : 2024-07-18

Pay. Date : 2024-06-12

DMF Number : 35780

Submission : 2021-04-13

Status : Active

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Submission : 1982-02-03

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Antibioticos Spa

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Henan Lihua Pharmaceutical Co Ltd

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Listed Suppliers

01

Symbiotec Pharmalab

India

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Fluorometholone

About the Company : Symbiotec, a leading API manufacturing company based in Indore, Central India, specializes in Cortico-Steroids and Steroid-Hormone APIs. Since 1995, their focus on R&D, sustainable...

Symbiotec, a leading API manufacturing company based in Indore, Central India, specializes in Cortico-Steroids and Steroid-Hormone APIs. Since 1995, their focus on R&D, sustainable operations, and innovation has driven their commitment to improving global healthcare access. With a state-of-the-art manufacturing facility inaugurated in 2004, Symbiotec has become a trusted provider in the industry. Their certifications including WHO-GMP, ISO, US FDA, and EU GMP showcase their dedication to quality and excellence. Over two decades, they've maintained their position through adaptability, efficiency, and competitive pricing.

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02

Gonane Pharma

India

Antibody Engineering

Not Confirmed

Gonane has API manufacturing expertise in new-age Corticosteroids, Hormones and other pharma raw materials.

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India

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Fluorometholone

About the Company : Gonane Pharma, is a contract pharmaceutical company located in Gujarat, India, specializing in the manufacturing and marketing of Corticosteroids, Hormones, Antivirals, and Oncolog...

Gonane Pharma, is a contract pharmaceutical company located in Gujarat, India, specializing in the manufacturing and marketing of Corticosteroids, Hormones, Antivirals, and Oncology products. The company's core strength lies in its dedicated team, and its promoters bring over 25 years of experience in manufacturing, promoting products, and managing audits for regulated markets such as the EU, Mexico, China, Korea, and Russia. GONANE PHARMA is actively engaged in discussions with Japanese customers and anticipates further expansion into additional markets.

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03

Axplora

Germany

Antibody Engineering

Not Confirmed

Axplora- The partner of choice for complex APIs.

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Germany

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Fluorometholone

About the Company : Axplora, created from the merger of Farmabios, Novasep & PharmaZell, is a leading API manufacturing partner to the world’s leading pharma & biotech companies, delivering top-qual...

Axplora, created from the merger of Farmabios, Novasep & PharmaZell, is a leading API manufacturing partner to the world’s leading pharma & biotech companies, delivering top-quality APIs on time & at scale, to the highest industry standards. It is dedicated to helping pharma companies make critical medicines safely to benefit patients. Leveraging our combined expertise & manufacturing capabilities across 9 industrial sites in the EU & India & an R&D facility in the USA, it offers CDMO services for small molecule APIs & biopharmaceuticals to innovators as well as APIs that address lifestyle-induced respiratory, inflammatory & liver diseases.

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04

EUROAPI

France

Antibody Engineering

Not Confirmed

EUROAPI, the leading small molecules API player, provides both API sales & CDMO services.

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France

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Fluorometholone

About the Company : EUROAPI is the market leader in small molecule APIs with projected sales of about €1 billion in 2022. With around 200 APIs, it has one of the largest portfolios in the market. Th...

EUROAPI is the market leader in small molecule APIs with projected sales of about €1 billion in 2022. With around 200 APIs, it has one of the largest portfolios in the market. Thanks to its excellent R&D skills and six manufacturing facilities across Europe, EUROAPI guarantees API manufacturing of the highest quality to its clients in over 80 countries. Its strong innovation and R&D skills helps it to speed the development of more complex molecule segments through CDMO operations. It also offers experience in supply, regulation and quality. EUROAPI employs 3,350 people and is listed on Euronext.

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05

TAPI Technology & API Services

Israel

CPhI WW Frankfurt

TAPI offers customized CDMO Solutions for API development and manufacturing services.

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Israel

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Fluorometholone

About the Company : Founded in 1935, TAPI Technology & API Services has a long-standing tradition of advancing health through innovation and dedication. Today, we proudly build upon this legacy, drivi...

Founded in 1935, TAPI Technology & API Services has a long-standing tradition of advancing health through innovation and dedication. Today, we proudly build upon this legacy, driving progress in the pharmaceutical industry. Leveraging our extensive experience and world-class expertise, we deliver one of the most comprehensive API portfolios in the industry. Additionally, we provide tailored CDMO services, harnessing our proficiency in diverse technologies to meet our partners' unique needs, ensuring flexibility and excellence in every project.

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06

Guangzhou Topwork Chemical

China

Antibody Engineering

Not Confirmed

07

Guangzhou Tosun Pharmaceutical

China

Antibody Engineering

Not Confirmed

08

Hangzhou Deli Chemical

China

Antibody Engineering

Not Confirmed

09

Maharshi Pharma Chem

India

Antibody Engineering

Not Confirmed

10

NEWCHEM SPA

Italy

Antibody Engineering

Not Confirmed

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Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country	Total Quantity (KGS)	Average Price (USD/KGS)	Number of Transactions

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DOSAGE - SUSPENSION/DROPS;OPHTHALMIC - 0.1%

USFDA APPLICATION NUMBER - 16851

DOSAGE - OINTMENT;OPHTHALMIC - 0.1%

USFDA APPLICATION NUMBER - 17760

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