DRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

Virtual Booth

Contact Supplier

Valsynthese, part of the SSE Group, is a CDMO focused on highly energetic and highly hazardous chemistry.

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

4 API Suppliers, 4 USDMF

4 API Suppliers
4 USDMF

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: 13551-89-8, Fmiso, Ro-07-0741, 1-(2-hydroxy-3-fluoropropyl)-2-nitroimidazole, 1-fluoro-3-(2-nitroimidazol-1-yl)propan-2-ol, Nsc-292930

Molecular Formula

C₆H₈FN₃O₃

Molecular Weight

189.14 g/mol

InChI Key

HIIJZYSUEJYLMX-UHFFFAOYSA-N

FDA UNII

082285VIDF

1 2D Structure

Fluoromisonidazole

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

1-fluoro-3-(2-nitroimidazol-1-yl)propan-2-ol

2.1.2 InChI

InChI=1S/C6H8FN3O3/c7-3-5(11)4-9-2-1-8-6(9)10(12)13/h1-2,5,11H,3-4H2

2.1.3 InChI Key

HIIJZYSUEJYLMX-UHFFFAOYSA-N

2.1.4 Canonical SMILES

C1=CN(C(=N1)[N+](=O)[O-])CC(CF)O

2.2 Other Identifiers

2.2.1 UNII

082285VIDF

2.3 Synonyms

2.3.1 MeSH Synonyms

1. (f-18) Fluoromisonidazole

2. 1-(2-nitro-1-imidazolyl)-3-fluoro-2-propanol

3. 1-fluoro-2-hydroxypropyl-2-nitroimidazole

4. 1-fluoromisonidazole

5. 18f-fluoromisonidazole

6. 18f-fmiso

7. Fluoromisonidazole, 18f-labeled

8. Fluoromisonidazole, Tritium-labeled

9. Fluoronormethoxymisonidazole

10. Fmiso

11. Ro 07-0741

2.3.2 Depositor-Supplied Synonyms

1. 13551-89-8

2. Fmiso

3. Ro-07-0741

4. 1-(2-hydroxy-3-fluoropropyl)-2-nitroimidazole

5. 1-fluoro-3-(2-nitroimidazol-1-yl)propan-2-ol

6. Nsc-292930

7. 1h-imidazole-1-ethanol, .alpha.-(fluoromethyl)-2-nitro-

8. 082285vidf

9. 1-fluoro-3-(2-nitro-1h-imidazol-1-yl)propan-2-ol

10. Nsc292930

11. Ku-2210

12. Sr-1367

13. 1h-imidazole-1-ethanol,a-(fluoromethyl)-2-nitro-

14. 1h-imidazole-1-ethanol, Alpha-(fluoromethyl)-2-nitro (9ci)

15. Fluoromisonidazole; Ku 2210; Nsc 292930; Ro 07-0741; Sr 1367

16. Misonidazole, Fluoro-

17. 1-(2-nitro-1-imidazolyl)-3-fluoro-2-propanol

18. Nsc 292930

19. Ku 2210

20. Sr 1367

21. Sr 1369

22. Brn 0522249

23. Unii-082285vidf

24. Alpha-(fluoromethyl)-2-nitroimidazole-1-ethanol

25. 1-fluoro-3-(2-nitro-imidazol-1-yl)-propan-2-ol

26. Schembl368122

27. Imidazole-1-ethanol, Alpha-(fluoromethyl)-2-nitro-

28. 1h-imidazole-1-ethanol, Alpha-(fluoromethyl)-2-nitro

29. Chembl2068841

30. Dtxsid30875662

31. Akos006279809

32. Ft-0691079

33. 1-(3-f-2-ohpropyl)-2-no2 Imidazole

34. 1-(2-nitro-1-imidazolyl)-2-hydroxy-3-fluoropropane

35. Alpha-fluoromethyl-2-nitroimidazole-1-ethanol

36. Q27236348

37. 1-fluoro-3-(2-(hydroxy(oxido)amino)-1h-imidazol-1-yl)-2-propanol

2.4 Create Date

2005-03-26

3 Chemical and Physical Properties

Molecular Formula	C₆H₈FN₃O₃
Molecular Weight	189.14 g/mol
XLogP3	-0.5
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	3
Exact Mass	189.05496929 g/mol
Monoisotopic Mass	189.05496929 g/mol
Topological Polar Surface Area	83.9 Å²
Heavy Atom Count	13
Formal Charge	0
Complexity	187
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Radiation-Sensitizing Agents

Drugs used to potentiate the effectiveness of radiation therapy in destroying unwanted cells. (See all compounds classified as Radiation-Sensitizing Agents.)

API SUPPLIERS