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Chemistry

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Also known as: 10163-15-2, Sodium fluorophosphate, Disodium monofluorophosphate, Disodium fluorophosphate, Sodium phosphorofluoridate, 7631-97-2
Molecular Formula
FNa2O3P
Molecular Weight
143.950  g/mol
InChI Key
BFDWBSRJQZPEEB-UHFFFAOYSA-L
FDA UNII
C810JCZ56Q

Fluorophosphate
Sodium monofluorophosphate is used in OTC dental preparations to help protect against cavities.
1 2D Structure

Fluorophosphate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
disodium;fluoro-dioxido-oxo-5-phosphane
2.1.2 InChI
InChI=1S/FH2O3P.2Na/c1-5(2,3)4;;/h(H2,2,3,4);;/q;2*+1/p-2
2.1.3 InChI Key
BFDWBSRJQZPEEB-UHFFFAOYSA-L
2.1.4 Canonical SMILES
[O-]P(=O)([O-])F.[Na+].[Na+]
2.2 Other Identifiers
2.2.1 UNII
C810JCZ56Q
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Ammonium Monofluorophosphate

2. Calcium Fluorophosphate

3. Calcium Monofluorophosphate

4. Fluorophosphate

5. Fluorophosphate Hydrate, Calcium Salt

6. Fluorophosphate, Barium Salt

7. Fluorophosphate, Calcium Salt

8. Fluorophosphate, Diammonium Salt

9. Fluorophosphate, Disodium Salt

10. Fluorophosphate, Monoammonium Salt

11. Fluorophosphate, Potassium Salt

12. Fluorophosphate, Sodium Salt

13. Fluorophosphate, Tin Salt

14. Fluorophosphate, Vanadium Salt

15. Mono-tridin

16. Monofluorophosphate

17. Na-mfp

2.3.2 Depositor-Supplied Synonyms

1. 10163-15-2

2. Sodium Fluorophosphate

3. Disodium Monofluorophosphate

4. Disodium Fluorophosphate

5. Sodium Phosphorofluoridate

6. 7631-97-2

7. Phosphorofluoridic Acid, Disodium Salt

8. Disodium Phosphorofluoridate

9. Acorea

10. Sodium Fluorophosphate (na2po3f)

11. Phosphorofluoridic Acid, Sodium Salt

12. C810jcz56q

13. 12331-99-6

14. Disodium;fluoro-dioxido-oxo-lambda5-phosphane

15. Chebi:86431

16. Sodium Monofluorophosphate [usp]

17. Nsc-248

18. Phosphorofluoridic Acid, Disodium Salt (8ci,9ci)

19. Mfcd00014248

20. Extra-strength Aim

21. Sodium Monofluorophosphate (usp)

22. Sodium Monofluorophosphate (inci)

23. Sodium Monofluorophosphate [inci]

24. Ccris 9129

25. Nsc 248

26. Disodiummonofluorophosphate

27. Einecs 233-433-0

28. Colgate Anticavity Toothpaste

29. Unii-c810jcz56q

30. F-o3-p.2na

31. Ai3-16931

32. Fluorophosphoric Acid, Sodium Salt

33. Sodium Fluophosphate

34. Einecs 231-552-2

35. Phoskadent Na211

36. Sodiumphosphorofluoridate

37. Sodium Phosphorofluridate

38. Aim (tn)

39. Disodium Phosphofluoridate

40. Disodiumphosphorofluoridate

41. Disodium Fluoro-dioxido-oxo-$l^{5}-phosphane

42. Ec 233-433-0

43. Na2-p-f-o3

44. Sodium Fluorophosphate, 95%

45. Sodiumfluorophosphate(na2po3f)

46. Sodium Monofluorphosphate

47. Phosphorofluoridicacid,sodiumsalt

48. Sodium Monofluorophosphate, Usp

49. Chembl1908359

50. F-h2-o3-p

51. Dtxsid70872554

52. Hms3264b14

53. Phosphorofluoridic Acid,sodium Salt

54. Phosphorofluoridicacid, Sodium Salt

55. Amy37031

56. Fluoridophosphoric Acid Disodium Salt

57. Phosphorofluoridic Acid Disodium Salt

58. S4013

59. Akos015916166

60. Akos015960447

61. Ccg-213673

62. Db09484

63. Sodium Fluorophosphate [who-dd]

64. Superlist Name Sodium Monofluorophosphate

65. Sodium Monofluorophosphate [mart.]

66. Sy061225

67. Sodium Monofluorophosphate [usp-rs]

68. Phosphorofluoridic Acid, Disodium Salt Smfp

69. Disodium;fluoro-dioxido-oxo-$l^{5-phosphane

70. Ft-0688148

71. Phosphorofluoridic Acid, Sodium Salt (1:?)

72. D05864

73. Sodium Monofluorophosphate [orange Book]

74. A838673

75. Sodium Monofluorophosphate [usp Monograph]

76. Q3498849

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 143.950 g/mol
Molecular Formula FNa2O3P
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count0
Exact Mass143.93644758 g/mol
Monoisotopic Mass143.93644758 g/mol
Topological Polar Surface Area63.2 Ų
Heavy Atom Count7
Formal Charge0
Complexity49.8
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count3
4 Drug and Medication Information
4.1 Drug Indication

Sodium monofluorophosphate is indicated for the treatment of cavities


5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

Cariostatic Agents

Substances that inhibit or arrest DENTAL CARIES formation. (Boucher's Clinical Dental Terminology, 4th ed) (See all compounds classified as Cariostatic Agents.)


5.2 ATC Code

A - Alimentary tract and metabolism

A01 - Stomatological preparations

A01A - Stomatological preparations

A01AA - Caries prophylactic agents

A01AA02 - Sodium monofluorophosphate


A - Alimentary tract and metabolism

A12 - Mineral supplements

A12C - Other mineral supplements

A12CD - Fluoride

A12CD02 - Sodium monofluorophosphate


API Reference Price

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PARK,KASA"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1731695400,"product":"O-(7-AZABENZOTRIAZOL-1-YL)-N,N,N\\',N\\'-TETRAMETHYL URONIUMHEXAFLUOROPHOSPHATE","address":"3-5-1037\/1,,VITTALWADI NARAYANAGUD","city":"HYDERABAD,TELANGANA","supplier":"BLD PHARMATECH LTD..,","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"BLD PHARMATECH INDIA ","customerCountry":"INDIA","quantity":"0.10","actualQuantity":"100","unit":"GMS","unitRateFc":"0.1","totalValueFC":"12.3","currency":"USD","unitRateINR":"10.3","date":"16-Nov-2024","totalValueINR":"1033.84","totalValueInUsd":"12.3","indian_port":"Bangalore Air","hs_no":"29339990","bill_no":"6712597","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"UNIT A1-A3 9\/F DRAGON INDUSTRIAL 93 KING LAM STREET LAI CHI KOK KOWLOO N Hong Kong, , HONG KONG HONG KONG","customerAddress":"3-5-1037\/1,,VITTALWADI NARAYANAGUD"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1732127400,"product":"O-BENZOTRIAZOLE-N.N.N.N-TETRAMETHYL-URONIUM-HEXAFLUOROPHOSPHATE ( FOR R & D PURPOSE CHEMICAL INTERMIDATES )","address":"142-48 S.V.ROAD,","city":"MUMBAI, MAHARASHTRA","supplier":"QINGDAO KINGWAY PHARMATECH ","supplierCountry":"CHINA","foreign_port":"BEIJING","customer":"FDC","customerCountry":"INDIA","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"145","totalValueFC":"732.8","currency":"USD","unitRateINR":"12368.5","date":"21-Nov-2024","totalValueINR":"61842.5","totalValueInUsd":"732.8","indian_port":"Bombay Air","hs_no":"29329990","bill_no":"6790308","productDescription":"Intermediate","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BEIJING","supplierAddress":"NO 88, MIDDLE HAIXI ROADJIAONAN CIT Y, QINGDAO SDNF CHINA","customerAddress":"142-48 S.V.ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1732300200,"product":"O-BENZOTRIAZOLE-N.N.N.N-TETRAMETHYL-URONIUM-HEXAFLUOROPHOSPHATE ( FOR R & D PURPOSE CHEMICAL INTERMIDATES )","address":"142-48 S.V.ROAD,","city":"MUMBAI, MAHARASHTRA","supplier":"QINGDAO KINGWAY PHARMATECH ","supplierCountry":"CHINA","foreign_port":"BEIJING","customer":"FDC","customerCountry":"INDIA","quantity":"10.00","actualQuantity":"10","unit":"KGS","unitRateFc":"125","totalValueFC":"1264.2","currency":"USD","unitRateINR":"10668.8","date":"23-Nov-2024","totalValueINR":"106687.5","totalValueInUsd":"1264.2","indian_port":"Bombay Air","hs_no":"29329990","bill_no":"6839371","productDescription":"Intermediate","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BEIJING","supplierAddress":"NO 88, MIDDLE HAIXI ROADJIAONAN CIT Y, QINGDAO SDNF CHINA","customerAddress":"142-48 S.V.ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1732818600,"product":"0-(7-AZABENZOTRIAZOL-1-YL)-N,N,N,\\'N,\\'-TETRANETHYL URONIUM HEXAFLUOROPHOSPHATE","address":"3-5-1037\/1,,VITTALWADI NARAYANAGUD","city":"HYDERABAD,TELANGANA","supplier":"BLD PHARMATECH LTD..,","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"BLD PHARMATECH INDIA ","customerCountry":"INDIA","quantity":"0.10","actualQuantity":"100","unit":"GMS","unitRateFc":"0.1","totalValueFC":"13.2","currency":"USD","unitRateINR":"11.1","date":"29-Nov-2024","totalValueINR":"1112.96","totalValueInUsd":"13.2","indian_port":"Bangalore Air","hs_no":"29339990","bill_no":"6951259","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"UNIT A1-A3 9\/F DRAGON INDUSTRIAL 93 KING LAM STREET LAI CHI KOK KOWLOO N Hong Kong, , HONG KONG HONG KONG","customerAddress":"3-5-1037\/1,,VITTALWADI NARAYANAGUD"}]
11-Jan-2021
29-Nov-2024
KGS
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Quantity (KGS) & Unit rate (USD/KGS) over time

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ABOUT THIS PAGE

Fluorophosphate Manufacturers

A Fluorophosphate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Fluorophosphate, including repackagers and relabelers. The FDA regulates Fluorophosphate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Fluorophosphate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Fluorophosphate Suppliers

A Fluorophosphate supplier is an individual or a company that provides Fluorophosphate active pharmaceutical ingredient (API) or Fluorophosphate finished formulations upon request. The Fluorophosphate suppliers may include Fluorophosphate API manufacturers, exporters, distributors and traders.

click here to find a list of Fluorophosphate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Fluorophosphate USDMF

A Fluorophosphate DMF (Drug Master File) is a document detailing the whole manufacturing process of Fluorophosphate active pharmaceutical ingredient (API) in detail. Different forms of Fluorophosphate DMFs exist exist since differing nations have different regulations, such as Fluorophosphate USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Fluorophosphate DMF submitted to regulatory agencies in the US is known as a USDMF. Fluorophosphate USDMF includes data on Fluorophosphate's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Fluorophosphate USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Fluorophosphate suppliers with USDMF on PharmaCompass.

Fluorophosphate NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Fluorophosphate as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Fluorophosphate API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Fluorophosphate as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Fluorophosphate and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Fluorophosphate NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Fluorophosphate suppliers with NDC on PharmaCompass.

Fluorophosphate GMP

Fluorophosphate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Fluorophosphate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Fluorophosphate GMP manufacturer or Fluorophosphate GMP API supplier for your needs.

Fluorophosphate CoA

A Fluorophosphate CoA (Certificate of Analysis) is a formal document that attests to Fluorophosphate's compliance with Fluorophosphate specifications and serves as a tool for batch-level quality control.

Fluorophosphate CoA mostly includes findings from lab analyses of a specific batch. For each Fluorophosphate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Fluorophosphate may be tested according to a variety of international standards, such as European Pharmacopoeia (Fluorophosphate EP), Fluorophosphate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Fluorophosphate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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