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Fluralaner

Seqens Fluralaner

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Suanfarma Fluralaner

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xyz-pharma-m-2024-10-07

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Rochem Fluralaner

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CHSD Fluralaner

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xyz-pharma-m-2024-10-07

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ACTIVE PHARMA INGREDIENTS

11 API Suppliers, 2 NDC API, 7 VMF, 11 Listed Suppliers, $ API Reference Price

11 API Suppliers
2 NDC API
7 VMF
11 Listed Suppliers
$ API Reference Price

INTERMEDIATES

10 Intermediates Suppliers

10 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

25 FDF Dossiers, 20 Canada, 5 Listed Dossiers

25 FDF Dossiers
20 Canada
5 Listed Dossiers

DIGITAL CONTENT

7 NEWS #PharmaBuzz

media
7 NEWS #PharmaBuzz

MARKET PLACE

6 APIs

marketPlace
6 APIs

Seqens Fluralaner

Synopsis

ACTIVE PHARMA INGREDIENTS

11

API Suppliers

0

USDMF

0

CEP/COS

CEP/COS Certifications

0

JDMF

0

EU WC

0

KDMF

2

NDC API

7

VMF

11

Listed Suppliers

API REF. PRICE (USD/KG)

$

$ 10,646

MARKET PLACE

6

API

0

FDF

10INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

25

FDF Dossiers

0

FDA Orange Book

FDA (Orange Book)

0

Europe

20

Canada

0

Australia

0

South Africa

5

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

0

EDQM

0

USP

0

JP

0

Others

PATENTS & EXCLUSIVITIES

0

US Patents

0

US Exclusivities

0

Health Canada Patents

DIGITAL CONTENT

0

Data Compilation #PharmaFlow

0

Stock Recap #PipelineProspector

0

Weekly News Recap #Phispers

7

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

NA

Annual Reports (USD Million)

NA

Finished Drug Prices

NA

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: Gs7l1rur5i, (r)-a-1443, A-663, 1122022-03-0, Benzamide, 4-((5r)-5-(3,5-dichlorophenyl)-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl)-2-methyl-n-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)-, Unii-gs7l1rur5i

Molecular Formula

C₂₂H₁₇Cl₂F₆N₃O₃

Molecular Weight

556.3 g/mol

InChI Key

MLBZKOGAMRTSKP-HXUWFJFHSA-N

FDA UNII

GS7L1RUR5I

Fluralaner

1 2D Structure

Fluralaner

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

4-[(5R)-5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4H-1,2-oxazol-3-yl]-2-methyl-N-[2-oxo-2-(2,2,2-trifluoroethylamino)ethyl]benzamide

2.1.2 InChI

InChI=1S/C22H17Cl2F6N3O3/c1-11-4-12(2-3-16(11)19(35)31-9-18(34)32-10-21(25,26)27)17-8-20(36-33-17,22(28,29)30)13-5-14(23)7-15(24)6-13/h2-7H,8-10H2,1H3,(H,31,35)(H,32,34)/t20-/m1/s1

2.1.3 InChI Key

MLBZKOGAMRTSKP-HXUWFJFHSA-N

2.1.4 Canonical SMILES

CC1=C(C=CC(=C1)C2=NOC(C2)(C3=CC(=CC(=C3)Cl)Cl)C(F)(F)F)C(=O)NCC(=O)NCC(F)(F)F

2.1.5 Isomeric SMILES

CC1=C(C=CC(=C1)C2=NO[C@](C2)(C3=CC(=CC(=C3)Cl)Cl)C(F)(F)F)C(=O)NCC(=O)NCC(F)(F)F

2.2 Other Identifiers

2.2.1 UNII

GS7L1RUR5I

2.3 Synonyms

2.3.1 Depositor-Supplied Synonyms

1. Gs7l1rur5i

2. (r)-a-1443

3. A-663

4. 1122022-03-0

5. Benzamide, 4-((5r)-5-(3,5-dichlorophenyl)-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl)-2-methyl-n-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)-

6. Unii-gs7l1rur5i

7. Schembl8515337

8. Dtxsid301101022

9. 4-[(5r)-5-(3,5-dichlorophenyl)-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-2-methyl-n-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]benzamide

2.4 Create Date

2013-04-19

3 Chemical and Physical Properties

Molecular Formula	C₂₂H₁₇Cl₂F₆N₃O₃
Molecular Weight	556.3 g/mol
XLogP3	5.6
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	10
Rotatable Bond Count	6
Exact Mass	555.0551158 g/mol
Monoisotopic Mass	555.0551158 g/mol
Topological Polar Surface Area	79.8 Å²
Heavy Atom Count	36
Formal Charge	0
Complexity	846
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

API SUPPLIERS

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NDC API

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VMF

01

Fabbrica Italiana Sintetici

Italy

BioFlorida Conference

Not Confirmed

02

Livzon Group Fuzhou Fuxing Pharmaceuti...

China

BioFlorida Conference

Not Confirmed

03

Nissan Chemical Co

Japan

BioFlorida Conference

Not Confirmed

04

Nissan Chemical Co

Japan

BioFlorida Conference

Not Confirmed

05

Nissan Chemical Co

Japan

BioFlorida Conference

Not Confirmed

06

Sichuan Qingmu Pharmaceutical Co Ltd

China

BioFlorida Conference

Not Confirmed

07

Wisdom Pharmaceutical Co Ltd

China

BioFlorida Conference

Not Confirmed

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Listed Suppliers

01

Seqens

France

BioFlorida Conference

Not Confirmed

Seqens is an integrated global leader in pharmaceutical solutions & specialty ingredients & provides custom-made solutions.

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France

Digital Content

About the Company : Since its inception in 2003, Seqens has grown to become a global leader in pharmaceutical solutions and specialty ingredients. Seqens supports its customers in developing, scaling ...

Since its inception in 2003, Seqens has grown to become a global leader in pharmaceutical solutions and specialty ingredients. Seqens supports its customers in developing, scaling up and manufacturing drug substances from the pre-clinical phase to the commercial phase. It offers a large portfolio of APIs and proprietary products. Seqens also develops custom solutions and ingredients for the most demanding industries, such as healthcare, electronics and cosmetics. Its unique range of technologies enables it to manufacture complex molecules for small- and large-scale demands. It operates 24 industrial plants and 10 R&D centres across the globe.

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Digital Content

02

Rochem International Inc

U.S.A

Suppliers Night Expo

Rochem, your partner in developing, sourcing, and supplying pharmaceutical & animal health ingredients of Chinese origin.

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U.S.A

Digital Content

About the Company : Established in 1994, Rochem is a distributor of pharmaceutical, food, nutritional and animal health ingredients to some of the largest companies in the world. It sources high-quali...

Established in 1994, Rochem is a distributor of pharmaceutical, food, nutritional and animal health ingredients to some of the largest companies in the world. It sources high-quality ingredients manufactured in China. Headquartered in the Hauppauge, New York, Rochem has 16 offices spread across the globe to cater to the needs of its customers. Rochem’s operations are fully cGMP compliant and has been audited by the USFDA as well as several multinational organizations. It also trains and audits its partners to ensure all of their technologies and systems are FDA-compliant.

Product Web Link

Digital Content

03

Suanfarma

Spain

CPhI India 2024

Suanfarma, at the Core of a Better Life.

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Spain

Digital Content

About the Company : Suanfarma founded in 1993, is a B2B life science partner committed to health & innovation by developing, manufacturing, & distributing high-quality APIs for the pharmaceutical indu...

Suanfarma founded in 1993, is a B2B life science partner committed to health & innovation by developing, manufacturing, & distributing high-quality APIs for the pharmaceutical industry innovatively & sustainably. Backed by a robust global network of 12 strategically located local offices, we cater to the needs of over 400 active customers in 70+ countries. At Suanfarma we offer our CDMO capacity for fermentation & chemical synthesis projects, offering a One Stop Shop service with a solid track record, & which allows us to achieve success in the development, scaling, manufacturing, & commercialization of an API, either innovative or generic.

Product Web Link

Digital Content

04

Shandong Chenghui Shuangda Pharmace...

China

BioFlorida Conference

Not Confirmed

Shuangda Pharmaceutical has a world-class first-class production line, having GMP, FDA and other regulatory certifications.

Contact Supplier

Contact Supplier

China

Digital Content

About the Company : Shandong Chenghui Shuangda Pharmaceutical Co., Ltd. is specialized in R&D and production of APIs and advanced intermediates. With 22 years of production experience,the company has ...

Shandong Chenghui Shuangda Pharmaceutical Co., Ltd. is specialized in R&D and production of APIs and advanced intermediates. With 22 years of production experience,the company has 6 workshops and 9 production lines which has 100t/month production capacity.The company is committed to maintain the standards with continuous improvements to the current standards throughout the product lifecycle.The main products include local anesthetic drugs, antiviral drugs, cardiovascular and cerebrovascular drugs, antitumor drugs, gastrointestinal drugs, diabetic drugs, veterinary drugs, and CDMO products.

Shandong Chenghui Shuangda Pharmaceutical

Product Web Link

Digital Content

05

ChemWerth Inc

U.S.A

BioFlorida Conference

Not Confirmed

ChemWerth works in generic API development & supply, non-infringement patent strategy development and regulatory support.

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U.S.A

Digital Content

About the Company : Established in 1982, ChemWerth is a US-headquartered full-service generic active pharmaceutical ingredient (API) development and supply company. ChemWerth offers cGMP-quality APIs ...

Established in 1982, ChemWerth is a US-headquartered full-service generic active pharmaceutical ingredient (API) development and supply company. ChemWerth offers cGMP-quality APIs to regulated markets worldwide and has exclusive partnerships for new product development, compliance support and secure supply chain logistics. ChemWerth has access to over 500 APIs and more than 30 manufacturing facilities in the US, Europe, India and China. ChemWerth acts as a regulatory agent for over 25 FDA-approved facilities and sells more than 100 products. It has established its presence in 38 countries. In 2020, ChemWerth filed its 500th DMF with the FDA.

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Product Web Link

Digital Content

06

Jinan Tantu Chemicals

China

BioFlorida Conference

Not Confirmed

Jinan Tantu Chemicals offers customized R&D services & production of small molecule APIs & pharmaceutical intermediates.

Contact Supplier

Contact Supplier

China

Digital Content

About the Company : Jinan Tantu Chemicals Co., Ltd. operates as a Contract Development and Manufacturing Organization (CDMO) that serves pharmaceutical companies worldwide. Our core services include c...

Jinan Tantu Chemicals Co., Ltd. operates as a Contract Development and Manufacturing Organization (CDMO) that serves pharmaceutical companies worldwide. Our core services include customized R&D as well as the production of small molecule pharmaceutical intermediates and Active Pharmaceutical Ingredients (APIs) for both international and domestic pharmaceutical firms. Our capabilities span from laboratory-scale kilograms to commercial ton-scale production. Additionally, we are committed to independent research and development, as well as the production and sales of high-end pharmaceutical intermediates and API products.

Jinan Tantu Chemicals

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Digital Content

07

Supriya Lifescience

India

CPhI India 2024

Supriya Lifesciences is a cGMP-compliant API manufacturing organization with a leadership position across key & niche products.

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India

Digital Content

About the Company : Supriya Lifescience Ltd. specializes in API manufacturing, focusing on therapeutic segments like antihistamines, anti-allergic drugs, vitamins, anaesthetics and anti-asthmatics. Su...

Supriya Lifescience Ltd. specializes in API manufacturing, focusing on therapeutic segments like antihistamines, anti-allergic drugs, vitamins, anaesthetics and anti-asthmatics. Supriya follows industry standards and constantly improves to deliver quality products. Its facility is 47,000 square meters with dedicated areas for warehouse, QA, QC, R&D, production and finished products. The current capacity is 550 KL, with plans to expand to over 1000 KL by 2024. Supriya has 14 active USDMFs, 8 active CEPs, strong R&D and compliant facilities worldwide. Supriya works with innovators, generic companies, and as a CMO.

Product Web Link

Digital Content

08

Alivira Animal Health

India

BioFlorida Conference

Not Confirmed

09

BrightGene Bio-Medical Technology C...

China

BioFlorida Conference

Not Confirmed

10

Sichuan Qingmu Pharmaceutical

China

BioFlorida Conference

Not Confirmed

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API Reference Price

[{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q3","strtotime":1662575400,"product":"FLURALANER IH","address":"301 3RD FLOOR ESQUARE SUBHASH ROAD VILE PARLE EAST Contac","city":"MUMBAI","supplier":"NGL FINE CHEM ","supplierCountry":"INDIA","foreign_port":"GUADALAJARA","customer":"CONSIGNEE NAME ADDRESS ","customerCountry":"MEXICO","quantity":"0.25","actualQuantity":"0.25","unit":"KGS","unitRateFc":"15600","totalValueFC":"3419","currency":"USD","unitRateINR":1096000,"date":"08-Sep-2022","totalValueINR":"274000","totalValueInUsd":"3419","indian_port":"BOMBAY AIR","hs_no":"29349990","bill_no":"4055607","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"MEXICO","selfForZScoreResived":"Pharma Grade","supplierPort":"BOMBAY AIR","supplierAddress":"301 3RD FLOOR ESQUARE SUBHASH ROAD VILE PARLE EAST Contac, MUMBAI","customerAddress":""},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q2","strtotime":1651602600,"product":"FLURALANER (FOR R & D PURPOSE)","address":"CORPORATE HOUSE, NR. SOLA BRIDGE,, S.G. HIGHWAY, THALTEJ","city":"AHMEDABAD,GUJARAT","supplier":"WISDOM PHARMACEUTICAL","supplierCountry":"CHINA","foreign_port":"NA","customer":"INTAS PHARMACEUTICALS","customerCountry":"INDIA","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"11000","totalValueFC":"10980.7","currency":"USD","unitRateINR":"848650","date":"04-May-2022","totalValueINR":"848650","totalValueInUsd":"10980.7","indian_port":"BOMBAY AIR","hs_no":"29339990","bill_no":"8542017","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"CORPORATE HOUSE, NR. SOLA BRIDGE,, S.G. HIGHWAY, THALTEJ"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1665426600,"product":"FLURALANER (FOR R & D PURPOSE)","address":"CORPORATE HOUSE, NR. SOLA BRIDGE,, S.G. HIGHWAY, THALTEJ","city":"AHMEDABAD,GUJARAT","supplier":"LIVZON PHARMACEUTICAL GROUP","supplierCountry":"CHINA","foreign_port":"NA","customer":"INTAS PHARMACEUTICALS","customerCountry":"INDIA","quantity":"4.00","actualQuantity":"4","unit":"KGS","unitRateFc":"12000","totalValueFC":"48096.7","currency":"USD","unitRateINR":"989400","date":"11-Oct-2022","totalValueINR":"3957600","totalValueInUsd":"48096.7","indian_port":"BOMBAY AIR","hs_no":"29339990","bill_no":"2820049","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"CORPORATE HOUSE, NR. SOLA BRIDGE,, S.G. HIGHWAY, THALTEJ"}]

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country	Total Quantity (KGS)	Average Price (USD/KGS)	Number of Transactions

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INTERMEDIATES SUPPLIERS

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FDF Dossiers

01

Supriya Lifescience

India

CPhI India 2024

Supriya Lifesciences is a cGMP-compliant API manufacturing organization with a leadership position across key & niche products.

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India

Digital Content

Regulatory Info :

Registration Country : India

Brand Name :

Dosage Form : Chewable Tablet

Dosage Strength : 112.5MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

Product Web Link

Digital Content

02

Supriya Lifescience

India

CPhI India 2024

Supriya Lifesciences is a cGMP-compliant API manufacturing organization with a leadership position across key & niche products.

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India

Digital Content

Regulatory Info :

Registration Country : India

Brand Name :

Dosage Form : Chewable Tablet

Dosage Strength : 250MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

Product Web Link

Digital Content

03

Supriya Lifescience

India

CPhI India 2024

Supriya Lifesciences is a cGMP-compliant API manufacturing organization with a leadership position across key & niche products.

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Contact Supplier

India

Digital Content

Regulatory Info :

Registration Country : India

Brand Name :

Dosage Form : Chewable Tablet

Dosage Strength : 500MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

Product Web Link

Digital Content

04

Supriya Lifescience

India

CPhI India 2024

Supriya Lifesciences is a cGMP-compliant API manufacturing organization with a leadership position across key & niche products.

Contact Supplier

Contact Supplier

India

Digital Content

Regulatory Info :

Registration Country : India

Brand Name :

Dosage Form : Chewable Tablet

Dosage Strength : 1000MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

Product Web Link

Digital Content

05

Supriya Lifescience

India

CPhI India 2024

Supriya Lifesciences is a cGMP-compliant API manufacturing organization with a leadership position across key & niche products.

Contact Supplier

Contact Supplier

India

Digital Content

Regulatory Info :

Registration Country : India

Brand Name :

Dosage Form : Chewable Tablet

Dosage Strength : 1400MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

Product Web Link

Digital Content

06

Merck & Co

U.S.A

Fi Europe 2024

Not Confirmed

07

Merck & Co

U.S.A

Fi Europe 2024

Not Confirmed

08

Merck & Co

U.S.A

Fi Europe 2024

Not Confirmed

09

Merck & Co

U.S.A

Fi Europe 2024

Not Confirmed

10

Merck & Co

U.S.A

Fi Europe 2024

Not Confirmed

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Canada

01

INTERVET CANADA CORP

U.S.A

BioFlorida Conference

Not Confirmed

02

INTERVET CANADA CORP

U.S.A

BioFlorida Conference

Not Confirmed

03

INTERVET CANADA CORP

U.S.A

BioFlorida Conference

Not Confirmed

04

INTERVET CANADA CORP

U.S.A

BioFlorida Conference

Not Confirmed

05

INTERVET CANADA CORP

U.S.A

BioFlorida Conference

Not Confirmed

06

INTERVET CANADA CORP

U.S.A

BioFlorida Conference

Not Confirmed

07

INTERVET CANADA CORP

U.S.A

BioFlorida Conference

Not Confirmed

08

INTERVET CANADA CORP

U.S.A

BioFlorida Conference

Not Confirmed

09

INTERVET CANADA CORP

U.S.A

BioFlorida Conference

Not Confirmed

10

INTERVET CANADA CORP

U.S.A

BioFlorida Conference

Not Confirmed

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APIs

Fluralaner API needed in India [ENA18465]

A leading pharmaceutical company with over three decades of experience in manufacturing of active ingredients & intermediates is looking for suppliers of Fluralaner API for commercial purposes. The suppliers must support this enquiry with CoA.

Reply

27 Oct 2023

Various APIs needed in India [ENA17451]

A company that focuses on research, development and manufacturing of finished formulations is looking for suppliers of Various APIs for development purposes. The required quantity is 200 g for each. The suppliers must support this enquiry with open part DMF & CoA. 1. Carprofen API 2. Clindamycin API 3. Clomipramine HCl API 4. Febantel API 5. Fluralaner API 6. Ivermectin API 7. Milbemycin API 8. Pimobendan API 9. Praziquantel API 10. Pyrantel Pamoate API 11. Robenacoxib API

Reply

03 Jul 2023

Fluralaner API needed in Mexico [ENA08879]

Moléculas finas de México, a distributor based in Mexico is looking for suppliers of Fluralaner API for developmental purposes. Interested suppliers can contact them via their email: Comprastrafico@moleculas-finas.com.mx.

Reply

23 Oct 2020

Various APIs needed in India [ENA08562]

A large CRO that focuses on global discovery, development & manufacturing, providing integrated scientific services to pharmaceutical, biotechnology, nutrition, animal health, consumer goods, and specialty chemical industries is looking for suppliers of Various APIs. The suppliers must support this enquiry with USDMF & CoA. The final market is the US & EU. 1. USNF and Ph. Eur. Grade Moxidectin (3 kg) API 2. USNF and Ph. Eur. Grade Pyrantel Pamoate (150 kg) API 3. USNF and Ph. Eur. Grade Praziquantel (100 kg) API 4. USNF and Ph. Eur. Grade Fluralaner (100 kg) API 5. USNF and Ph. Eur. Grade Sarolaner (100 kg) API 6. USNF and Ph. Eur. Grade Monepantel (150 kg) API

Reply

16 Sep 2020

Milbemycin Oxime & Fluralaner API needed in India [ENA08121]

A manufacturing company based in India that deals in more than 10 portfolios is looking for suppliers of Milbemycin Oxime & Fluralaner API. The final market is African countries.

Reply

01 Aug 2020

Enquiry// Fluralaner API 200 kg needed in Hong Kong [ENA00467]

Vetapet & Associates Limited, one of the leading companion animal products suppliers in Hong Kong, offering over 1,600 items to the pet industry, from a small vial of vaccines to a huge aviary for parrots is searching for suppliers of Fluralaner API 200 kg for domestic consumption. Interested suppliers/manufacturers should contact Poi Chan via Email: poichan@hotmail.com or Tel: 852 94563289.

Reply

25 Aug 2017

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