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9 CEP/COS
11 JDMF
4 EU WC
8 KDMF
14 NDC API
19 Listed Suppliers
$ API Reference Price

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5 Intermediates Suppliers

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16 FDA Orange Book
12 Europe
2 Canada
4 South Africa
6 Listed Dossiers

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Synopsis

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Chemistry

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Also known as: 5104-49-4, Ansaid, Froben, Antadys, 2-(2-fluorobiphenyl-4-yl)propanoic acid, Cebutid

Molecular Formula

C₁₅H₁₃FO₂

Molecular Weight

244.26 g/mol

InChI Key

SYTBZMRGLBWNTM-UHFFFAOYSA-N

FDA UNII

5GRO578KLP

An anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.

Flurbiprofen is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of flurbiprofen is as a Cyclooxygenase Inhibitor.

1 2D Structure

Flurbiprofen

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

2-(3-fluoro-4-phenylphenyl)propanoic acid

2.1.2 InChI

InChI=1S/C15H13FO2/c1-10(15(17)18)12-7-8-13(14(16)9-12)11-5-3-2-4-6-11/h2-10H,1H3,(H,17,18)

2.1.3 InChI Key

SYTBZMRGLBWNTM-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CC(C1=CC(=C(C=C1)C2=CC=CC=C2)F)C(=O)O

2.2 Other Identifiers

2.2.1 UNII

5GRO578KLP

2.3 Synonyms

2.3.1 MeSH Synonyms

1. 2-fluoro-alpha-methyl-(1,1'-biphenyl)-4-acetic Acid

2. Ansaid

3. Apo Flurbiprofen

4. Apo-flurbiprofen

5. Bts 18322

6. Bts-18322

7. Bts18322

8. Cebutid

9. Dobrofen

10. E 7869

11. E-7869

12. E7869

13. Flubiprofen

14. Flugalin

15. Flurbiprofen Sodium

16. Fluriproben

17. Froben

18. Froben Sr

19. Neo Artrol

20. Novo Flurprofen

21. Novo-flurprofen

22. Nu Flurbiprofen

23. Nu-flurbiprofen

24. Ocufen

25. Ocuflur

26. Ratio Flurbiprofen

27. Ratio-flurbiprofen

28. Strefen

2.3.2 Depositor-Supplied Synonyms

1. 5104-49-4

2. Ansaid

3. Froben

4. Antadys

5. 2-(2-fluorobiphenyl-4-yl)propanoic Acid

6. Cebutid

7. Flurofen

8. 3-fluoro-4-phenylhydratropic Acid

9. 2-(3-fluoro-4-phenylphenyl)propanoic Acid

10. Ocufen

11. Flurbiprofene [inn-french]

12. Flurbiprofenum [inn-latin]

13. Flurbiprofeno [inn-spanish]

14. Bts 18322

15. Bts-18322

16. Fp 70

17. U-27182

18. 2-fluoro-alpha-methyl-(1,1'-biphenyl)-4-acetic Acid

19. (+-)-2-fluoro-alpha-methyl-4-biphenylacetic Acid

20. 2-(2-fluorobiphenyl-4-yl)propionic Acid

21. Mfcd00079303

22. Stayban

23. Zepolas

24. Adfeed

25. U 27182

26. 2-(2-fluoro-[1,1'-biphenyl]-4-yl)propanoic Acid

27. 51543-38-5

28. Chembl563

29. Bts 18,322

30. Nsc-757037

31. 5gro578klp

32. 2-(2-fluoro-4-biphenylyl)propionic Acid

33. (r)-flurbiprofen;mpc7869

34. Mls000040873

35. Chebi:5130

36. Flubiprofen

37. Flugalin

38. Einecs 257-262-6

39. U-27,182

40. (1)-2-fluoro-alpha-methyl(1,1'-biphenyl)-4-acetic Acid

41. Flurbiprofene

42. Flurbiprofeno

43. Flurbiprofenum

44. 2-fluoro-alpha-methyl-4-biphenylacetic Acid

45. Ocuflur

46. Smr000042823

47. Dsstox_cid_17231

48. Dsstox_rid_79310

49. Dsstox_gsid_37231

50. C15h13fo2

51. Anmetarin

52. Yakuban

53. Dl-flurbiprofen

54. Flurbiprofen (ansaid)

55. Ansaid (tn)

56. Ccris 3708

57. Sr-01000003043

58. Flp

59. Einecs 225-827-6

60. (+-)-2-(2-fluoro-4-biphenylyl)propionic Acid

61. Unii-5gro578klp

62. (+/-)-2-fluoro-alpha-methyl-4-biphenylacetic Acid

63. Mpc7869

64. U 27,182

65. Flurbiprofen O

66. Mks-11

67. Rac-flurbiprofen

68. Flurbiprofen,(s)

69. Ncgc00016654-01

70. (+-)flurbiprofen

71. Cas-5104-49-4

72. Ocufen (salt/mix)

73. [1,1'-biphenyl]-4-acetic Acid, 2-fluoro-?-methyl-

74. Flurbiprofen [usan:usp:inn:ban:jan]

75. Spectrum_001096

76. Opera_id_777

77. Prestwick0_000917

78. Prestwick1_000917

79. Prestwick2_000917

80. Prestwick3_000917

81. Spectrum2_001025

82. Spectrum3_000435

83. Spectrum4_000558

84. Spectrum5_000720

85. Flurbiprofen [mi]

86. 2-(3-fluoro-4-phenyl-phenyl)propanoic Acid

87. F0371

88. (.+/-.)-flurbiprofen

89. Flurbiprofen [inn]

90. Flurbiprofen [jan]

91. 4-biphenylacetic Acid, 2-fluoro-alpha-methyl-

92. Flurbiprofen [usan]

93. Schembl2248

94. Flurbiprofen [vandf]

95. 4-biphenylacetic Acid, 2-fluoro-.alpha.-methyl-

96. Bspbio_000794

97. Bspbio_002050

98. Flurbiprofen [mart.]

99. Kbiogr_001255

100. Kbioss_001576

101. 2-(2-fluoro[1,1'-biphenyl]-4-yl)propanoic Acid

102. Mls000028441

103. Mls000758198

104. Mls001201729

105. Mls001401361

106. Mls006011431

107. Mls006011931

108. Divk1c_000804

109. Flurbiprofen [usp-rs]

110. Flurbiprofen [who-dd]

111. Spectrum1500308

112. 2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic Acid

113. Spbio_001209

114. Spbio_002983

115. Bpbio1_000874

116. Gtpl4194

117. Dtxsid0037231

118. Schembl10029029

119. Flurbiprofen (jp17/usp/inn)

120. Hms502i06

121. Kbio1_000804

122. Kbio2_001576

123. Kbio2_004144

124. Kbio2_006712

125. Kbio3_001270

126. Sytbzmrglbwntm-uhfffaoysa-

127. [1,1'-biphenyl]-4-acetic Acid, 2-fluoro-.alpha.-methyl-

128. Ninds_000804

129. Flurbiprofen [orange Book]

130. Hms1570h16

131. Hms1920o20

132. Hms2051a05

133. Hms2090i06

134. Hms2091f21

135. Hms2097h16

136. Hms2232i08

137. Hms3259i12

138. Hms3268e10

139. Hms3370n14

140. Hms3371i05

141. Hms3393a05

142. Hms3414n17

143. Hms3649k11

144. Hms3655g19

145. Hms3678n15

146. Hms3714h16

147. Pharmakon1600-01500308

148. Flurbiprofen [ep Monograph]

149. (1,1'-biphenyl)-4-acetic Acid, 2-fluoro-alpha-methyl-, (+-)-

150. Bcp09086

151. Bcp13426

152. Flurbiprofen [usp Monograph]

153. Tox21_110547

154. Tox21_302353

155. Bbl010980

156. Bdbm50074922

157. Ccg-40243

158. Flurbiprofen - Cas 5104-49-4

159. Nsc685701

160. Nsc755404

161. Nsc757037

162. Stk802101

163. Flurbiprofen, Cyclooxygenase Inhibitor

164. Akos004119934

165. Akos016340701

166. Ac-8106

167. Ccg-100759

168. Db00712

169. Ks-5035

170. Nc00009

171. Nc00563

172. Nsc 757037

173. Nsc-685701

174. Nsc-755404

175. 2(2-fluoro-4-biphenylyl)propionic Acid

176. Idi1_000804

177. Ncgc00018157-03

178. Ncgc00018157-04

179. Ncgc00018157-05

180. Ncgc00018157-08

181. Ncgc00018157-11

182. Ncgc00018157-13

183. Ncgc00025287-03

184. Ncgc00025287-04

185. Ncgc00255457-01

186. Hy-10582

187. Nci60_030812

188. 2 -(2-fluoro-4-biphenylyl)propionic Acid

189. 2-(2-fluoro-4-biphenylyl)-propionic Acid

190. 2-(2-fluoro-biphenyl-4-yl)propionic Acid

191. Sbi-0051387.p003

192. Db-051888

193. Flurbiprofen 100 Microg/ml In Acetonitrile

194. 2-(2-fluoro-biphenyl-4-yl)-propionic Acid

195. Ab00051999

196. Ft-0603668

197. Ft-0660285

198. Ft-0668760

199. Ft-0771103

200. Alpha-methyl-2-fluoro-4-biphenylylacetic Acid

201. (rs)-2-(2-fluorobiphenyl-4-yl)propionic Acid

202. 2-fluoro-.alpha.-methyl-4-biphenylacetic Acid

203. Bim-0051387.0001

204. C07013

205. D00330

206. Ab00051999-17

207. Ab00051999_18

208. 104f494

209. 2-(2-fluoro-1,1'-biphenyl-4-yl)propanoic Acid

210. 2-fluoro--methyl-(1,1'-biphenyl)-4-acetic Acid

211. Ao-295/42284050

212. Q419890

213. (.+/-.)-2-(2-fluoro-4-biphenylyl)propionic Acid

214. (r/s)-2-fluoro-alpha-methyl-4-biphenylacetic Acid

215. 2-fluoro-?-methyl-[1,1'-biphenyl]-4-acetic Acid

216. Flurbiprofen, Antibiotic For Culture Media Use Only

217. Q-201129

218. Sr-01000003043-2

219. Sr-01000003043-5

220. Sr-01000003043-6

221. (s)-(+)-2-fluoro-alpha-methyl-4-biphenylaceticacid

222. 2-(2-fluoro-[1,1''-biphenyl-4-yl])propanoic Acid

223. 2-(2-fluoro[1,1'-biphenyl]-4-yl)propanoic Acid #

224. Brd-a86044036-001-05-9

225. Sr-01000003043-14

226. (+/-)-2-(2-fluoro-4-biphenylyl)propionic Acid

227. (.+/-.)-2-fluoro-.alpha.-methyl-4-biphenylacetic Acid

228. 2-fluoro-.alpha.-methyl(1,1'-biphenyl)-4-acetic Acid

229. 2-fluoro-alpha-methyl-(1,1''-biphenyl)-4-acetic Acid

230. 2-fluoro-alpha-methyl-[1,1'-biphenyl]-4-a Cetic Acid

231. (+/-)-2-fluoro-.alpha.-methyl-4-biphenylacetic Acid

232. Flurbiprofen, European Pharmacopoeia (ep) Reference Standard

233. (1,1'-biphenyl)-4-acetic Acid, 2-fluoro-alpha-methyl-, (+/-)-

234. Flurbiprofen, United States Pharmacopeia (usp) Reference Standard

235. [1,1'-biphenyl]-4-acetic Acid, 2-fluoro-.alpha.-methyl-, (.+/-.)-

236. (1,1'-biphenyl)-4-acetic Acid, 2-fluoro-.alpha.-methyl-, (+/-)-

237. Flurbiprofen, Pharmaceutical Secondary Standard; Certified Reference Material

2.4 Create Date

2005-03-25

3 Chemical and Physical Properties

Molecular Formula	C₁₅H₁₃FO₂
Molecular Weight	244.26 g/mol
XLogP3	4.2
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	3
Exact Mass	244.08995782 g/mol
Monoisotopic Mass	244.08995782 g/mol
Topological Polar Surface Area	37.3 Å²
Heavy Atom Count	18
Formal Charge	0
Complexity	286
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Drug and Medication Information

4.1 Drug Information

1 of 6
Drug Name	Ansaid
PubMed Health	Flurbiprofen
Drug Classes	Analgesic, Antirheumatic, Central Nervous System Agent, Musculoskeletal Agent, NSAID, Ophthalmologic Agent, Propionic Acid
Drug Label	Flurbiprofen tablet, USP contain flurbiprofen, which is a member of the phenylalkanoic acid derivative group of nonsteroidal anti-inflammatory drugs. Flurbiprofen tablet, USP are white, oval, film-coated tablets for oral administration. Flurbiprofen...
Active Ingredient	Flurbiprofen
Dosage Form	Tablet
Route	Oral
Strength	100mg; 50mg
Market Status	Prescription
Company	Pharmacia And Upjohn

2 of 6
Drug Name	Flurbiprofen
PubMed Health	Flurbiprofen
Drug Classes	Analgesic, Antirheumatic, Central Nervous System Agent, Musculoskeletal Agent, NSAID, Ophthalmologic Agent, Propionic Acid
Drug Label	OCUFEN (flurbiprofen sodium ophthalmic solution, USP) 0.03% is a sterile topical nonsteroidal anti-inflammatory product for ophthalmic use. Chemical Name:Sodium ()-2-(2-fluoro-4-biphenylyl) propionate dihydrate. Structural Formula:C15H12FNaO22...
Active Ingredient	Flurbiprofen
Dosage Form	Tablet
Route	Oral
Strength	100mg; 50mg
Market Status	Prescription
Company	Teva; Sun Pharm Inds; Mylan

3 of 6
Drug Name	Ocufen
PubMed Health	Flurbiprofen
Drug Classes	Analgesic, Antirheumatic, Central Nervous System Agent, Musculoskeletal Agent, NSAID, Ophthalmologic Agent, Propionic Acid
Active Ingredient	Flurbiprofen sodium
Dosage Form	Solution/drops
Route	Ophthalmic
Strength	0.03%
Market Status	Prescription
Company	Allergan

4 of 6
Drug Name	Ansaid
PubMed Health	Flurbiprofen
Drug Classes	Analgesic, Antirheumatic, Central Nervous System Agent, Musculoskeletal Agent, NSAID, Ophthalmologic Agent, Propionic Acid
Drug Label	Flurbiprofen tablet, USP contain flurbiprofen, which is a member of the phenylalkanoic acid derivative group of nonsteroidal anti-inflammatory drugs. Flurbiprofen tablet, USP are white, oval, film-coated tablets for oral administration. Flurbiprofen...
Active Ingredient	Flurbiprofen
Dosage Form	Tablet
Route	Oral
Strength	100mg; 50mg
Market Status	Prescription
Company	Pharmacia And Upjohn

5 of 6
Drug Name	Flurbiprofen
PubMed Health	Flurbiprofen
Drug Classes	Analgesic, Antirheumatic, Central Nervous System Agent, Musculoskeletal Agent, NSAID, Ophthalmologic Agent, Propionic Acid
Drug Label	OCUFEN (flurbiprofen sodium ophthalmic solution, USP) 0.03% is a sterile topical nonsteroidal anti-inflammatory product for ophthalmic use. Chemical Name:Sodium ()-2-(2-fluoro-4-biphenylyl) propionate dihydrate. Structural Formula:C15H12FNaO22...
Active Ingredient	Flurbiprofen
Dosage Form	Tablet
Route	Oral
Strength	100mg; 50mg
Market Status	Prescription
Company	Teva; Sun Pharm Inds; Mylan

6 of 6
Drug Name	Ocufen
PubMed Health	Flurbiprofen
Drug Classes	Analgesic, Antirheumatic, Central Nervous System Agent, Musculoskeletal Agent, NSAID, Ophthalmologic Agent, Propionic Acid
Active Ingredient	Flurbiprofen sodium
Dosage Form	Solution/drops
Route	Ophthalmic
Strength	0.03%
Market Status	Prescription
Company	Allergan

4.2 Drug Indication

Flurbiprofen tablets are indicated for the acute or long-term symptomatic treatment of rheumatoid arthritis, osteorarthritis and anklosing spondylitis. It may also be used to treat pain associated with dysmenorrhea and mild to moderate pain accompanied by inflammation (e.g. bursitis, tendonitis, soft tissue trauma). Topical ophthalmic formulations may be used pre-operatively to prevent intraoperative miosis.

FDA Label

5 Pharmacology and Biochemistry

5.1 Pharmacology

Flurbiprofen, a nonsteroidal anti-inflammatory agent (NSAIA) of the propionic acid class, is structually and pharmacologically related to fenoprofen, ibuprofen, and ketoprofen, and has similar pharmacological actions to other prototypica NSAIAs. Flurbiprofen exhibits antiinflammatory, analgesic, and antipyretic activities. The commercially available flurbiprofen is a racemic mixture of (+)S- and (-) R-enantiomers. The S-enantiomer appears to possess most of the anti-inflammatory, while both enantiomers may possess analgesic activity.

5.2 MeSH Pharmacological Classification

Anti-Inflammatory Agents, Non-Steroidal

Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)

Cyclooxygenase Inhibitors

Compounds or agents that combine with cyclooxygenase (PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES) and thereby prevent its substrate-enzyme combination with arachidonic acid and the formation of eicosanoids, prostaglandins, and thromboxanes. (See all compounds classified as Cyclooxygenase Inhibitors.)

Analgesics

Compounds capable of relieving pain without the loss of CONSCIOUSNESS. (See all compounds classified as Analgesics.)

5.3 FDA Pharmacological Classification

5.3.1 Active Moiety

FLURBIPROFEN

5.3.2 FDA UNII

5GRO578KLP

5.3.3 Pharmacological Classes

Cyclooxygenase Inhibitors [MoA]; Nonsteroidal Anti-inflammatory Drug [EPC]; Anti-Inflammatory Agents, Non-Steroidal [CS]

5.4 ATC Code

R02AX01

S76 | LUXPHARMA | Pharmaceuticals Marketed in Luxembourg | Pharmaceuticals marketed in Luxembourg, as published by d'Gesondheetskeess (CNS, la caisse nationale de sante, www.cns.lu), mapped by name to structures using CompTox by R. Singh et al. (in prep.). List downloaded from https://cns.public.lu/en/legislations/textes-coordonnes/liste-med-comm.html. Dataset DOI:10.5281/zenodo.4587355

M - Musculo-skeletal system

M01 - Antiinflammatory and antirheumatic products

M01A - Antiinflammatory and antirheumatic products, non-steroids

M01AE - Propionic acid derivatives

M01AE09 - Flurbiprofen

M - Musculo-skeletal system

M02 - Topical products for joint and muscular pain

M02A - Topical products for joint and muscular pain

M02AA - Antiinflammatory preparations, non-steroids for topical use

M02AA19 - Flurbiprofen

R - Respiratory system

R02 - Throat preparations

R02A - Throat preparations

R02AX - Other throat preparations

R02AX01 - Flurbiprofen

S - Sensory organs

S01 - Ophthalmologicals

S01B - Antiinflammatory agents

S01BC - Antiinflammatory agents, non-steroids

S01BC04 - Flurbiprofen

5.5 Absorption, Distribution and Excretion

Absorption

Fluribiprofen is rapidly and almost completely absorbed following oral administration. Peak plasma concentrations are reached 0.5 - 4 hours after oral administration.

Route of Elimination

Flurbiprofen is poorly excreted into human milk. Following dosing with flurbiprofen, less than 3% of flurbiprofen is excreted unchanged in the urine, with about 70% of the dose eliminated in the urine as parent drug and metabolites. Renal elimination is a significant pathway of elimination of flurbiprofen metabolites.

Volume of Distribution

14 L [Normal Healthy Adults]

12 L [Geriatric Arthritis Patients]

10 L [End Stage Renal Disease Patients]

14 L [Alcoholic Cirrhosis Patients]

0.12 L/kg

5.6 Metabolism/Metabolites

Hepatic. Cytochrome P450 2C9 plays an important role in the metabolism of flurbiprofen to its major metabolite, 4’-hydroxy-flurbiprofen. The 4’-hydroxy-flurbiprofen metabolite showed little anti-inflammatory activity in animal models of inflammation.

5.7 Biological Half-Life

R-flurbiprofen, 4.7 hours; S-flurbiprofen, 5.7 hours

5.8 Mechanism of Action

Similar to other NSAIAs, the anti-inflammatory effect of flurbiprofen occurs via reversible inhibition of cyclooxygenase (COX), the enzyme responsible for the conversion of arachidonic acid to prostaglandin G2 (PGG2) and PGG2 to prostaglandin H2 (PGH2) in the prostaglandin synthesis pathway. This effectively decreases the concentration of prostaglandins involved in inflammation, pain, swelling and fever. Flurbiprofen is a non-selective COX inhibitor and inhibits the activity of both COX-1 and -2. It is also one of the most potent NSAIAs in terms of prostaglandin inhibitory activity.

API SUPPLIERS

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Pharma, Lab & Chemical Expo

Not Confirmed

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India

Virtual Booth

Digital Content

USDMF

CEP/COS

JDMF

EU-WC

NDC

KDMF

VMF Others AUDIT

Product Web Link

06

Catalytica

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Pharma, Lab & Chemical Expo

Not Confirmed

07

Forest Laboratories

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Pharma, Lab & Chemical Expo

Not Confirmed

08

Forest Laboratories

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Pharma, Lab & Chemical Expo

Not Confirmed

09

Zambon Group SpA

Italy

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Pharma, Lab & Chemical Expo

Not Confirmed

10

F. Hoffmann-La Roche

Switzerland

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Pharma, Lab & Chemical Expo

Not Confirmed

Only 10 entries up to this point, click to access all

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USDMF

01

Ra Chem Pharma Ltd

India

BIO Partnering at JPM

Not Confirmed

Cohance Lifesciences, offers full range of CDMO services for small molecule APIs, intermediates, ADCs, Pellets and Formulations.

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India

Virtual Booth

Digital Content

FLURBIPROFEN USP

GDUFA

DMF Review : N/A

Rev. Date :

Pay. Date :

DMF Number : 33995

Submission : 2019-07-12

Status : Active

Type : II

02

Pharmaron Manufacturing Services (uk...

United Kingdom

BIO Partnering at JPM

Not Confirmed

03

Wyckoff Chemical Co Inc

India

BIO Partnering at JPM

Not Confirmed

04

Erregierre Spa

Italy

Italy

BIO Partnering at JPM

Not Confirmed

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CEP/COS

01

COHANCE LIFESCIENCES LIMITED Hydera...

India

BIO Partnering at JPM

Not Confirmed

Cohance Lifesciences, offers full range of CDMO services for small molecule APIs, intermediates, ADCs, Pellets and Formulations.

Contact Supplier

India

Virtual Booth

Digital Content

Flurbiprofen

Certificate Number : R1-CEP 2016-063 - Rev 00

Status : Valid

Issue Date : 2023-05-26

Type : Chemical

Substance Number : 1519

02

FDC Limited Mumbai IN

BIO Partnering at JPM

Not Confirmed

08

SUN PHARMACEUTICAL INDUSTRIES LIMIT...

India

BIO Partnering at JPM

Not Confirmed

09

SUN PHARMACEUTICAL INDUSTRIES LIMIT...

India

BIO Partnering at JPM

Not Confirmed

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JDMF

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EU WC

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KDMF

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NDC API

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Listed Suppliers

01

Metrochem API Private Limited

India

BIO Partnering at JPM

Not Confirmed

Metrochem has been delivering customized volume & quality products to customers across the world, taking utmost care of their needs.

Contact Supplier

India

Virtual Booth

Digital Content

Flurbiprofen

About the Company :

Established in 2004, Metrochem API is one of the fastest-growing APIs, pellets & intermediates manufacturers. It has 6 dedicated manufacturing facilities for its 3 core product ...

Established in 2004, Metrochem API is one of the fastest-growing APIs, pellets & intermediates manufacturers. It has 6 dedicated manufacturing facilities for its 3 core product groups and has been approved by ISO 9001-2015, USFDA, WHO GMP, Cofepris & Japanese authorities. Metrochem’s in-depth industry knowledge, & hi-tech & advanced infrastructure, helps it provide quality products to its customers. Note: None of the products will be supplied to the countries where this could conflict with existing patents. Further, any products under patent will be offered for R&D purposes only. However, the final responsibility lies with the buyer

02

Cohance Lifesciences

India

BIO Partnering at JPM

Not Confirmed

Cohance Lifesciences, offers full range of CDMO services for small molecule APIs, intermediates, ADCs, Pellets and Formulations.

Contact Supplier

India

Virtual Booth

Digital Content

Flurbiprofen

About the Company : Cohance Lifesciences is a leading CDMO and API platform, offering products and services across all phases of a molecule’s lifecycle from development to commercialzation. With our...

Cohance Lifesciences is a leading CDMO and API platform, offering products and services across all phases of a molecule’s lifecycle from development to commercialzation. With our expertise in complex chemistries, we provide end-to-end CDMO services to global innovators and have delivered numerous projects from concept to commercialization over the years.As a global API player, we serve customers across nearly 60 countries with 80+ molecules backed by robust R&D, regulatory capabilities and manufacturing infrastructure. We are among the top backward integrated exporters of pellets and have strong development and manufacturing capabilities.

03

Albemarle Corporation

U.S.A

BIO Partnering at JPM

Not Confirmed

04

Aspen Biopharma Labs

India

India

BIO Partnering at JPM

Not Confirmed

Only 10 entries up to this point, click to access all

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API Reference Price

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OF","customerCountry":"PAKISTAN","quantity":"150.00","actualQuantity":"150","unit":"KGS","unitRateFc":"90","totalValueFC":"13367.2","currency":"USD","unitRateINR":7488,"date":"29-Oct-2024","totalValueINR":"1123200","totalValueInUsd":"13367.2","indian_port":"Hyderabad ICD","hs_no":"29163990","bill_no":"5229366","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"PAKISTAN","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad ICD","supplierAddress":"PLOT NO.174,PROGRESSIVE INDUSTRIAL, TALUQ,MEDAK DIST.,A.P.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1730745000,"product":"FLURBIPROFEN JP","address":"142-48 S.V.ROAD,","city":"MUMBAI, MAHARASHTRA","supplier":"FDC","supplierCountry":"INDIA","foreign_port":"TOKYO - NARITA","customer":"CHEMIX INC.","customerCountry":"JAPAN","quantity":"193.00","actualQuantity":"193","unit":"KGS","unitRateFc":"22700","totalValueFC":"28358.2","currency":"JPY","unitRateINR":12399.464663212437,"date":"05-Nov-2024","totalValueINR":"2393096.68","totalValueInUsd":"28358.2","indian_port":"Bombay Air","hs_no":"29163190","bill_no":"5374427","productDescription":"API","marketType":"REGULATED MARKET","country":"JAPAN","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"142-48 S.V.ROAD,, MUMBAI, MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1730745000,"product":"FLURBIPROFEN JP","address":"142-48 S.V.ROAD,","city":"MUMBAI, MAHARASHTRA","supplier":"FDC","supplierCountry":"INDIA","foreign_port":"TOKYO - NARITA","customer":"CHEMIX INC.","customerCountry":"JAPAN","quantity":"387.00","actualQuantity":"387","unit":"KGS","unitRateFc":"22700","totalValueFC":"56863.3","currency":"JPY","unitRateINR":12399.465839793282,"date":"05-Nov-2024","totalValueINR":"4798593.28","totalValueInUsd":"56863.3","indian_port":"Bombay Air","hs_no":"29163190","bill_no":"5374427","productDescription":"API","marketType":"REGULATED MARKET","country":"JAPAN","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"142-48 S.V.ROAD,, MUMBAI, MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1731263400,"product":"PHARMACEUTICAL ALLOPATHIC RAW MATERIAL FLURBIPROFEN USP","address":"PLOT NO.174,PROGRESSIVE INDUSTRIAL","city":"TALUQ,MEDAK DIST.,A.P.","supplier":"HY-GRO CHEMICALS PHARMTEK","supplierCountry":"INDIA","foreign_port":"KARACHI","customer":"TO THE ORDER OF","customerCountry":"PAKISTAN","quantity":"100.00","actualQuantity":"100","unit":"KGS","unitRateFc":"90","totalValueFC":"8899.9","currency":"USD","unitRateINR":7510.5,"date":"11-Nov-2024","totalValueINR":"751050","totalValueInUsd":"8899.9","indian_port":"Hyderabad ICD","hs_no":"29163990","bill_no":"5510605","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"PAKISTAN","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad ICD","supplierAddress":"PLOT NO.174,PROGRESSIVE INDUSTRIAL, TALUQ,MEDAK DIST.,A.P.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1731436200,"product":"FLURBIPROFEN USP CAS NO 5104-49-4","address":"FLAT NO.202,RAMBADRI,SATYAM HEIGHT","city":"HYDERABAD,TELANGANA","supplier":"GMFC LABS PRIVATE ","supplierCountry":"INDIA","foreign_port":"JEBEL ALI","customer":"TRANSWORLD MIDDLE EAST ","customerCountry":"UNITED ARAB EMIRATES","quantity":"1250.00","actualQuantity":"1250","unit":"KGS","unitRateFc":"90","totalValueFC":"111249.3","currency":"USD","unitRateINR":7510.5,"date":"13-Nov-2024","totalValueINR":"9388125","totalValueInUsd":"111249.3","indian_port":"Hyderabad ICD","hs_no":"29163990","bill_no":"5572301","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"UNITED ARAB EMIRATES","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad ICD","supplierAddress":"FLAT NO.202,RAMBADRI,SATYAM HEIGHT, HYDERABAD,TELANGANA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1731695400,"product":"(PHARMACEUTICAL ALLOPATHIC RAW MATERIAL)FLURBIPROFEN-USP","address":"B-16, MADHURANAGAR,","city":"HYDERABAD. AP","supplier":"INCHEM LABORATORIES PRIVATE ","supplierCountry":"INDIA","foreign_port":"KARACHI","customer":"TO THE ORDER OF","customerCountry":"PAKISTAN","quantity":"200.00","actualQuantity":"200","unit":"KGS","unitRateFc":"91.5","totalValueFC":"18129.1","currency":"USD","unitRateINR":7649.3999999999996,"date":"16-Nov-2024","totalValueINR":"1529880","totalValueInUsd":"18129.1","indian_port":"Hyderabad ICD","hs_no":"29163990","bill_no":"5664109","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"PAKISTAN","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad ICD","supplierAddress":"B-16, MADHURANAGAR,, HYDERABAD. AP","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1732300200,"product":"FLURBIPROFEN EP","address":"142-48 S.V.ROAD,","city":"MUMBAI, MAHARASHTRA","supplier":"FDC","supplierCountry":"INDIA","foreign_port":"ALGIERS","customer":"S.A.R.L LABORATOIRE MERINAL","customerCountry":"ALGERIA","quantity":"600.00","actualQuantity":"600","unit":"KGS","unitRateFc":"160","totalValueFC":"92974.4","currency":"USD","unitRateINR":13076.5671,"date":"23-Nov-2024","totalValueINR":"7845940.26","totalValueInUsd":"92974.4","indian_port":"Bombay Air","hs_no":"29163190","bill_no":"5855506","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"ALGERIA","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"142-48 S.V.ROAD,, MUMBAI, MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1732732200,"product":"FLURBIPROFEN USP VIDE EXPORT INV.NO.6124010460 DTD.25.11.2024","address":"SYNO.257 258\/1, DNO.11-6\/56,","city":"VILLAGE BALANGAR POST HYDERABAD","supplier":"LEE PHARMA","supplierCountry":"INDIA","foreign_port":"KARACHI","customer":"CURATECH PHARMA PVT ","customerCountry":"PAKISTAN","quantity":"50.00","actualQuantity":"50","unit":"KGS","unitRateFc":"91","totalValueFC":"4507.5","currency":"USD","unitRateINR":7607.6000000000004,"date":"28-Nov-2024","totalValueINR":"380380","totalValueInUsd":"4507.5","indian_port":"Hyderabad ICD","hs_no":"29163990","bill_no":"5972885","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"PAKISTAN","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad ICD","supplierAddress":"SYNO.257 258\/1, DNO.11-6\/56,, VILLAGE BALANGAR POST HYDERABAD","customerAddress":""},{"dataSource":"API Import","activeIngredients":"","year":"2021","qtr":"Q4","strtotime":1633545000,"product":"FLURBIPROFEN USP\/BP\/EP","address":"PIRAMAL ANANTA, PIRAMAL AGASTYA PAR KAMANI JUNCTION, LBS MARG,","city":"KURLA, MUMBAI","supplier":"GRACE","supplierCountry":"UNITED STATES","foreign_port":"NA","customer":"PIRAMAL PHARMA SOLUTIONS","customerCountry":"INDIA","quantity":"500.00","actualQuantity":"500","unit":"KGS","unitRateFc":"615","totalValueFC":"312362.3","currency":"USD","unitRateINR":"46799.4","date":"07-Oct-2021","totalValueINR":"23399675.28","totalValueInUsd":"312362.3","indian_port":"BOMBAY AIR","hs_no":"29163990","bill_no":"5743182","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"PIRAMAL ANANTA, PIRAMAL AGASTYA PAR KAMANI JUNCTION, LBS MARG,"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q1","strtotime":1647628200,"product":"FLURBIPROFEN FX\/DRM 25KG","address":"PIRAMAL ANANTA, PIRAMAL AGASTYA PAR KAMANI JUNCTION, LBS MARG,","city":"KURLA, MUMBAI","supplier":"GRACE","supplierCountry":"UNITED STATES","foreign_port":"NA","customer":"PIRAMAL PHARMA SOLUTIONS","customerCountry":"INDIA","quantity":"150.00","actualQuantity":"150","unit":"KGS","unitRateFc":"689","totalValueFC":"107304.1","currency":"USD","unitRateINR":"54524.4","date":"19-Mar-2022","totalValueINR":"8178666.43","totalValueInUsd":"107304.1","indian_port":"BOMBAY AIR","hs_no":"29163990","bill_no":"7929900","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"PIRAMAL ANANTA, PIRAMAL AGASTYA PAR KAMANI JUNCTION, LBS MARG,"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1692901800,"product":"FLURBIPROFEN FX\/DRM 25KG USP & EP","address":"NA","city":"NA","supplier":"W R GRACE CO CONN","supplierCountry":"UNITED STATES","foreign_port":"NA","customer":"PIRAMAL PHARMA SOLUTIONS","customerCountry":"INDIA","quantity":"200.00","actualQuantity":"200","unit":"KGS","unitRateFc":"715","totalValueFC":"148215.5","currency":"USD","unitRateINR":"60774.2","date":"25-Aug-2023","totalValueINR":"12277623.12","totalValueInUsd":"148215.5","indian_port":"SAHAR AIR","hs_no":"29163990","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"NA"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1696357800,"product":"FLURBIPROFEN JP BATCH NO 023B005 (RE-IMPORT)","address":"142-48 S.V.ROAD,","city":"MUMBAI, MAHARASHTRA","supplier":"CHEMIX INC.","supplierCountry":"INDIA","foreign_port":"TOKYO - NARITA","customer":"FDC","customerCountry":"INDIA","quantity":"25.00","actualQuantity":"25","unit":"KGS","unitRateFc":"19700","totalValueFC":"3986","currency":"JPY","unitRateINR":"13270","date":"04-Oct-2023","totalValueINR":"331749.14","totalValueInUsd":"3986","indian_port":"Bombay Air","hs_no":"29163190","bill_no":"8143129","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"TOKYO - NARITA","supplierAddress":"2-15-10 SHINYOKOHAMA KOHOKU-KUYOKOHAMASDNF JAPAN","customerAddress":"142-48 S.V.ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1696357800,"product":"FLURBIPROFEN (BATCH NO ADFRBNF016) (RE IMPORT)","address":"ACME PLAZA, ANDHERI KURLA ROAD,","city":"MUMBAI, MAHARASHTRA.","supplier":"ABBOTT LABORATORIES","supplierCountry":"INDIA","foreign_port":"KARACHI -","customer":"SUN PHARMACEUTICAL INDUSTRIES LIMITED","customerCountry":"INDIA","quantity":"118.04","actualQuantity":"118.04","unit":"KGS","unitRateFc":"160","totalValueFC":"20650.8","currency":"USD","unitRateINR":"14560.7","date":"04-Oct-2023","totalValueINR":"1718749.07","totalValueInUsd":"20650.8","indian_port":"Bombay Air","hs_no":"29163990","bill_no":"8136511","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"KARACHI -","supplierAddress":"D HAYDBERABAD ROAD OPP RADIO PAKISTAN TRANSMISSION CENTRE KARACHI 750PAKISTAN PAKISTAN","customerAddress":"ACME PLAZA, ANDHERI KURLA ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1706293800,"product":"S-(+)-FLURBIPROFEN (REJECTED RETURN CARGO VIDE SB NO.6587252DT.08-JAN-24)","address":"PLOT NO.174,PROGRESSIVE INDUSTRIAL","city":"TALUQ,MEDAK DIST.,A.P.","supplier":"AR BROWN CO. LTD","supplierCountry":"INDIA","foreign_port":"OSAKA - KANSAI INT\\'L","customer":"HY-GRO CHEMICALS PHARMTEK","customerCountry":"INDIA","quantity":"30.00","actualQuantity":"30","unit":"KGS","unitRateFc":"900","totalValueFC":"27321.1","currency":"USD","unitRateINR":"75690","date":"27-Jan-2024","totalValueINR":"2270700","totalValueInUsd":"27321.1","indian_port":"Hyderabad Air","hs_no":"29163990","bill_no":"9850254","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"OSAKA - KANSAI INT\\'L","supplierAddress":"GINZA MITSUI BLDG.,8-13-1,GINZACHUO-KU, TOKYO,104-0061 JAPANSDNF JP","customerAddress":"PLOT NO.174,PROGRESSIVE INDUSTRIAL"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1728585000,"product":"FLURBIPROFEN FX\/DRM 25KG","address":"PIRAMAL ANANTA, PIRAMAL AGASTYA PARK","city":"KURLA, MUMBAI","supplier":"GRACE","supplierCountry":"UNITED STATES","foreign_port":"CHICAGO O\\'HARE INT\\'L","customer":"PIRAMAL PHARMA SOLUTIONS","customerCountry":"INDIA","quantity":"166.00","actualQuantity":"166","unit":"KGS","unitRateFc":"715","totalValueFC":"122775.7","currency":"USD","unitRateINR":"62147.1","date":"11-Oct-2024","totalValueINR":"10316418.84","totalValueInUsd":"122775.7","indian_port":"Bombay Air","hs_no":"29163990","bill_no":"6069561","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"CHICAGO O\\'HARE INT\\'L","supplierAddress":"7500 GRACE DRIVE COLUMBIA MD 21044 Columbia, , United States SDNF United States","customerAddress":"PIRAMAL ANANTA, PIRAMAL AGASTYA PARK"}]

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country	Total Quantity (KGS)	Average Price (USD/KGS)	Number of Transactions

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INTERMEDIATES SUPPLIERS

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FDF Dossiers

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FDA Orange Book

01

GENUS

U.S.A

BIO Partnering at JPM

Not Confirmed

02

IVAX SUB TEVA PHARMS

U.S.A

BIO Partnering at JPM

Not Confirmed

03

IVAX SUB TEVA PHARMS

Not Confirmed

10

SUN PHARM INDS INC

India

BIO Partnering at JPM

Not Confirmed

Only 10 entries up to this point, click to access all

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Europe

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Canada

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South Africa

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Listed Dossiers

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Related Excipient Companies

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Excipients by Applications

Click here to find the perfect excipient manufacturers by their capabilities

Fillers, Diluents & Binders

Coating Systems & Additives

Controlled & Modified Release

Direct Compression

Thickeners and Stabilizers

Granulation

Disintegrants & Superdisintegrants

Solubilizers

01

Nanjing Well Pharmaceutical

China

Biotech Showcase

Not Confirmed

Nanjing Well is focused on R&D, production & sales of Pharmaceutical Excipients & Synthetic Lubricating base oils.

Dosage Form : Capsule, Cream / Lotion / Ointment, Emulsion, Gel, Injectable / Parenteral, Suspension, Tablet

Grade : Parenteral, Oral, Topical

Category : Emulsifying Agents, Film Formers & Plasticizers, Parenteral, Solubilizers, Surfactant & Foaming Agents, Thickeners and Stabilizers, Topical

Brand Name : Polysorbate 80

Application : Emulsifying Agents, Film Formers & Plasticizers, Parenteral, Solubilizers, Surfactant & Foaming Agents, Thickeners and Stabilizers, Topical

Excipient Details : Polysorbate 80 is used as a plasticizer, solubilizer, emulsifier, surfactant, and suspension stabilizer. It is also used in parenteral products.

Pharmacopoeia Ref : ChP/USP/EP/JP

Technical Specs : NA

Ingredient(s) : Polysorbate 80

Excipients Web Link

France

Biotech Showcase

Not Confirmed

Only 10 entries up to this point, click to access all

Lubricants & Glidants

01

Faran Shimi Pharmaceutical

Iran

BIO Partnering at JPM

Not Confirmed

Faran Shimi: Leading producer of high-quality APIs & alkaloid opiates, serving major pharmaceutical companies across the Middle East.

Dosage Form : Tablet

Grade : Oral

Category : Lubricants & Glidants

Brand Name : Magnesium Stearate

Application : Lubricants & Glidants

Excipient Details : Magnesium stearate is the magnesium salt of stearic acid. It acts as a lubricating agent in tablet manufacturing.

Pharmacopoeia Ref : NA

Technical Specs : NA

Ingredient(s) : Magnesium Stearate

02

Gangwal Healthcare

India

BIO Partnering at JPM

Not Confirmed

Gangwal Healthcare is powered by innovation, driving health, wellness & healing.

Dosage Form : Capsule, Tablet

Grade : Oral

Category : Co-Processed Excipients, Direct Compression, Disintegrants & Superdisintegrants, Fillers, Diluents & Binders, Lubricants & Glidants

Brand Name : ProBlend®

Application : Co-Processed Excipients, Direct Compression, Disintegrants & Superdisintegrants, Fillers, Diluents & Binders, Lubricants & Glidants

Excipient Details : ProBlend (Microcrystalline Cellulose) is used as a filler, binder, glidant, DC & co-processed excipient in tablets, capsules, and MUPS formulations.

Pharmacopoeia Ref : USP-NF

Technical Specs : NA

Ingredient(s) : Microcrystalline Cellulose

03

Faran Shimi Pharmaceutical

Iran

BIO Partnering at JPM

Not Confirmed

Faran Shimi: Leading producer of high-quality APIs & alkaloid opiates, serving major pharmaceutical companies across the Middle East.

Dosage Form : Tablet

Grade : Oral

Category : Granulation

Brand Name : Sodium Dodecyl Sulfate

Application : Granulation

Excipient Details : Sodium dodecyl sulfate is used in wet granulation tableting applications for the production of antacid tablets and digestive aids.

Pharmacopoeia Ref : NA

Technical Specs : NA

Ingredient(s) : Sodium Dodecyl Sulfate Excipient

Excipients Web Link

Austria

BIO Partnering at JPM

Not Confirmed

Only 10 entries up to this point, click to access all

Co-Processed Excipients

01

Gangwal Healthcare

India

BIO Partnering at JPM

Not Confirmed

Gangwal Healthcare is powered by innovation, driving health, wellness & healing.

Dosage Form : Capsule, Tablet

Grade : Oral

Category : Co-Processed Excipients, Direct Compression, Fillers, Diluents & Binders

Brand Name : STARLOSE®

Application : Co-Processed Excipients, Direct Compression, Fillers, Diluents & Binders

Excipient Details : STARLOSE is used as a diluent, binder, directly compressible (DC), and co-processed excipient in tablets and capsules.

Pharmacopoeia Ref : IP/EP/USP-NF/IH

Technical Specs : NA

Ingredient(s) : Lactose Monohydrate

02

Gangwal Healthcare

India

BIO Partnering at JPM

Not Confirmed

Gangwal Healthcare is powered by innovation, driving health, wellness & healing.

Dosage Form : Capsule, Tablet

Grade : Oral

Category : Co-Processed Excipients, Direct Compression, Disintegrants & Superdisintegrants, Fillers, Diluents & Binders, Lubricants & Glidants

Brand Name : ProBlend®

Application : Co-Processed Excipients, Direct Compression, Disintegrants & Superdisintegrants, Fillers, Diluents & Binders, Lubricants & Glidants

Excipient Details : ProBlend (Microcrystalline Cellulose) is used as a filler, binder, glidant, DC & co-processed excipient in tablets, capsules, and MUPS formulations.

Pharmacopoeia Ref : USP-NF

Technical Specs : NA

Ingredient(s) : Microcrystalline Cellulose

03

Gangwal Healthcare

India

BIO Partnering at JPM

Not Confirmed

Gangwal Healthcare is powered by innovation, driving health, wellness & healing.

Dosage Form : Capsule, Tablet

Grade : Oral

Category : Co-Processed Excipients, Direct Compression, Fillers, Diluents & Binders

Brand Name : DiCOM-DC® PL009 P60

Application : Co-Processed Excipients, Direct Compression, Fillers, Diluents & Binders

Excipient Details : DiCOM-DC PL009 P60 is used as a filler, binder, directly compressible, and co-processed excipient in tablets and capsules.

Pharmacopoeia Ref : IH

Technical Specs : NA

Ingredient(s) : Maize Starch

04

Gangwal Healthcare

India

BIO Partnering at JPM

Not Confirmed

Gangwal Healthcare is powered by innovation, driving health, wellness & healing.

Dosage Form : Capsule, Tablet

Grade : Oral

Category : Co-Processed Excipients, Direct Compression, Fillers, Diluents & Binders, Thickeners and Stabilizers

Brand Name : DiCOM-DC® SP204

Application : Co-Processed Excipients, Direct Compression, Fillers, Diluents & Binders, Thickeners and Stabilizers

Excipient Details : DiCOM-DC SP204 is used as a stabilizer, filler, binder, directly compressible, and co-processed excipient in tablets and capsules.

Pharmacopoeia Ref : In-house

Technical Specs : NA

Ingredient(s) : Corn Starch, Pregelatinized

05

Gangwal Healthcare

India

BIO Partnering at JPM

Not Confirmed

Gangwal Healthcare is powered by innovation, driving health, wellness & healing.

Dosage Form : Capsule, Tablet

Grade : Oral

Category : Co-Processed Excipients, Controlled & Modified Release, Direct Compression

Brand Name : DiCOM-DC® SR300

Application : Co-Processed Excipients, Controlled & Modified Release, Direct Compression

Excipient Details : DiCOM-DC SR300 is used as a directly compressible, rate-controlling, and co-processed excipient in sustained-release tablets and capsules.

Pharmacopoeia Ref : In-house

Technical Specs : NA

Ingredient(s) : EthylCellulose

06

Gangwal Healthcare

India

BIO Partnering at JPM

Not Confirmed

Gangwal Healthcare is powered by innovation, driving health, wellness & healing.

Dosage Form : Capsule, Tablet

Grade : Oral

Category : Co-Processed Excipients, Direct Compression, Fillers, Diluents & Binders

Brand Name : Lactose DC

Application : Co-Processed Excipients, Direct Compression, Fillers, Diluents & Binders

Excipient Details : Lactose DC (Lactose Monohydrate) is used as a filler, binder, directly compressible, and co-processed excipient in tablets and capsules.

Pharmacopoeia Ref : IP, USP

Technical Specs : NA

Ingredient(s) : Lactose Monohydrate

07

Gangwal Healthcare

India

BIO Partnering at JPM

Not Confirmed

Gangwal Healthcare is powered by innovation, driving health, wellness & healing.

Dosage Form : Capsule, Tablet

Grade : Oral

Category : Co-Processed Excipients, Direct Compression, Fillers, Diluents & Binders

Brand Name : Microlose™ M60 P60

Application : Co-Processed Excipients, Direct Compression, Fillers, Diluents & Binders

Excipient Details : Microlose M60 P60 is used as a filler, binder, directly compressible, and co-processed excipient in tablets and capsules.

Pharmacopoeia Ref : In-house

Technical Specs : Lactose Monohydrate – 40%, Microcrystalline cellulose – 60%

Ingredient(s) : Lactose Monohydrate

Excipients Web Link

U.S.A

BIO Partnering at JPM

Not Confirmed

Only 10 entries up to this point, click to access all

Topical

Film Formers & Plasticizers

Parenteral

01

Seqens

France

BIO Partnering at JPM

Not Confirmed

Seqens is an integrated global leader in pharmaceutical solutions & specialty ingredients & provides custom-made solutions.

Dosage Form : Injectable / Parenteral

Grade : Parenteral

Category : Parenteral

Brand Name : Expansorb® PLA / PEG

Application : Parenteral

Excipient Details : Expansorb® PLA?/PEG? polymers are used as functional excipients in injectable formulations for controlled & slow drug release with a single injection.

Pharmacopoeia Ref : N/A

Technical Specs : Classic and ultrapure LMP

Ingredient(s) : Poly lactic acid

02

Faran Shimi Pharmaceutical

Iran

BIO Partnering at JPM

Not Confirmed

Faran Shimi: Leading producer of high-quality APIs & alkaloid opiates, serving major pharmaceutical companies across the Middle East.

Dosage Form : Tablet

Grade : Oral

Category : Fillers, Diluents & Binders

Brand Name : Lactose Monohydrate

Application : Fillers, Diluents & Binders

Excipient Details : Lactose monohydrate is widely used as a filler and diluent in solid dosage forms such as tablets.

Pharmacopoeia Ref : NA

Technical Specs : NA

Ingredient(s) : Lactose Monohydrate

03

Nanjing Well Pharmaceutical

China

BIO Partnering at JPM

Not Confirmed

Nanjing Well is focused on R&D, production & sales of Pharmaceutical Excipients & Synthetic Lubricating base oils.

Dosage Form : Capsule, Cream / Lotion / Ointment, Emulsion, Gel, Injectable / Parenteral, Suspension, Tablet

Grade : Parenteral, Oral, Topical

Category : Emulsifying Agents, Film Formers & Plasticizers, Parenteral, Solubilizers, Surfactant & Foaming Agents, Thickeners and Stabilizers, Topical

Brand Name : Polysorbate 80

Application : Emulsifying Agents, Film Formers & Plasticizers, Parenteral, Solubilizers, Surfactant & Foaming Agents, Thickeners and Stabilizers, Topical

Excipient Details : Polysorbate 80 is used as a plasticizer, solubilizer, emulsifier, surfactant, and suspension stabilizer. It is also used in parenteral products.

Pharmacopoeia Ref : ChP/USP/EP/JP

Technical Specs : NA

Ingredient(s) : Polysorbate 80

04

Seqens

France

BIO Partnering at JPM

Not Confirmed

Seqens is an integrated global leader in pharmaceutical solutions & specialty ingredients & provides custom-made solutions.

Dosage Form : Injectable / Parenteral

Grade : Parenteral

Category : Parenteral

Brand Name : Expansorb® PLGA / PEG

Application : Parenteral

Excipient Details : Expansorb® PLGA? / PEG copolymers are used as functional excipients in single dose injections for controlled and slow drug release (weeks to months).

Pharmacopoeia Ref : N/A

Technical Specs : Classic and ultrapure LMP

Ingredient(s) : Poly-DL-Lactic-co-Glycolic Acid

05

Pluviaendo

Turkey

BIO Partnering at JPM

Not Confirmed

06

Nanjing Well Pharmaceutical

China

Nanjing Well is focused on R&D, production & sales of Pharmaceutical Excipients & Synthetic Lubricating base oils.

Dosage Form : Cream / Lotion / Ointment, Gel, Injectable / Parenteral, Softgel Capsule, Softgels

Grade : Parenteral, Topical, Oral

Category : Fillers, Diluents & Binders, Film Formers & Plasticizers, Parenteral, Surfactant & Foaming Agents, Thickeners and Stabilizers, Topical

Brand Name : Polyethylene Glycol 400

Application : Fillers, Diluents & Binders, Film Formers & Plasticizers, Parenteral, Surfactant & Foaming Agents, Thickeners and Stabilizers, Topical

Excipient Details : PEG 400 is used as a suspending agent, stabilizer, plasticizer and filler in OSDs, liquids & semi-solids and as a solvent for parenteral formulations.

Pharmacopoeia Ref : ChP/USP/EP

Technical Specs : NA

Ingredient(s) : Polyethylene Glycol 400

07

Nanjing Well Pharmaceutical

China

BIO Partnering at JPM

Not Confirmed

Nanjing Well is focused on R&D, production & sales of Pharmaceutical Excipients & Synthetic Lubricating base oils.

Dosage Form : Injectable / Parenteral

Grade : Parenteral

Category : Parenteral

Brand Name : Lactose Monohydrate

Application : Parenteral

Excipient Details : Lactose monohydrate is used as a diluent in inhalation and lyophilized preparations.

Pharmacopoeia Ref : ChP/USP/EP/JP

Technical Specs : NA

Ingredient(s) : Lactose Monohydrate

08

Nanjing Bold Chemical

China

BIO Partnering at JPM

Not Confirmed

09

Finar

India

BIO Partnering at JPM

Not Confirmed

10

Actylis

U.S.A

BIO Partnering at JPM

Not Confirmed

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Emulsifying Agents

Taste Masking

Rheology Modifiers

Empty Capsules

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01

YMC

YMC CHIRAL ƒÀ-CD BR

Biotech Showcase

Not Confirmed

02

YMC

YMC CHIRAL ƒÁ-CD BR

Biotech Showcase

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ABOUT THIS PAGE

Flurbiprofen Manufacturers

A Flurbiprofen manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Flurbiprofen, including repackagers and relabelers. The FDA regulates Flurbiprofen manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Flurbiprofen API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Flurbiprofen manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Flurbiprofen Suppliers

A Flurbiprofen supplier is an individual or a company that provides Flurbiprofen active pharmaceutical ingredient (API) or Flurbiprofen finished formulations upon request. The Flurbiprofen suppliers may include Flurbiprofen API manufacturers, exporters, distributors and traders.

click here to find a list of Flurbiprofen suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Flurbiprofen USDMF

A Flurbiprofen DMF (Drug Master File) is a document detailing the whole manufacturing process of Flurbiprofen active pharmaceutical ingredient (API) in detail. Different forms of Flurbiprofen DMFs exist exist since differing nations have different regulations, such as Flurbiprofen USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Flurbiprofen DMF submitted to regulatory agencies in the US is known as a USDMF. Flurbiprofen USDMF includes data on Flurbiprofen's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Flurbiprofen USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Flurbiprofen suppliers with USDMF on PharmaCompass.

Flurbiprofen JDMF

The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

The Flurbiprofen Drug Master File in Japan (Flurbiprofen JDMF) empowers Flurbiprofen API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

PMDA reviews the Flurbiprofen JDMF during the approval evaluation for pharmaceutical products. At the time of Flurbiprofen JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

click here to find a list of Flurbiprofen suppliers with JDMF on PharmaCompass.

Flurbiprofen KDMF

In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

Pharmaceutical companies submit a Flurbiprofen Drug Master File in Korea (Flurbiprofen KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Flurbiprofen. The MFDS reviews the Flurbiprofen KDMF as part of the drug registration process and uses the information provided in the Flurbiprofen KDMF to evaluate the safety and efficacy of the drug.

After submitting a Flurbiprofen KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Flurbiprofen API can apply through the Korea Drug Master File (KDMF).

click here to find a list of Flurbiprofen suppliers with KDMF on PharmaCompass.

Flurbiprofen CEP

A Flurbiprofen CEP of the European Pharmacopoeia monograph is often referred to as a Flurbiprofen Certificate of Suitability (COS). The purpose of a Flurbiprofen CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Flurbiprofen EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Flurbiprofen to their clients by showing that a Flurbiprofen CEP has been issued for it. The manufacturer submits a Flurbiprofen CEP (COS) as part of the market authorization procedure, and it takes on the role of a Flurbiprofen CEP holder for the record. Additionally, the data presented in the Flurbiprofen CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Flurbiprofen DMF.

A Flurbiprofen CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Flurbiprofen CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

click here to find a list of Flurbiprofen suppliers with CEP (COS) on PharmaCompass.

Flurbiprofen WC

A Flurbiprofen written confirmation (Flurbiprofen WC) is an official document issued by a regulatory agency to a Flurbiprofen manufacturer, verifying that the manufacturing facility of a Flurbiprofen active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Flurbiprofen APIs or Flurbiprofen finished pharmaceutical products to another nation, regulatory agencies frequently require a Flurbiprofen WC (written confirmation) as part of the regulatory process.

click here to find a list of Flurbiprofen suppliers with Written Confirmation (WC) on PharmaCompass.

Flurbiprofen NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Flurbiprofen as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Flurbiprofen API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Flurbiprofen as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Flurbiprofen and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Flurbiprofen NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Flurbiprofen suppliers with NDC on PharmaCompass.

Flurbiprofen GMP

Flurbiprofen Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Flurbiprofen GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Flurbiprofen GMP manufacturer or Flurbiprofen GMP API supplier for your needs.

Flurbiprofen CoA

A Flurbiprofen CoA (Certificate of Analysis) is a formal document that attests to Flurbiprofen's compliance with Flurbiprofen specifications and serves as a tool for batch-level quality control.

Flurbiprofen CoA mostly includes findings from lab analyses of a specific batch. For each Flurbiprofen CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Flurbiprofen may be tested according to a variety of international standards, such as European Pharmacopoeia (Flurbiprofen EP), Flurbiprofen JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Flurbiprofen USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.

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CHEMISTRY

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ACTIVE PHARMA INGREDIENTS

40 API Suppliers

12 USDMF

9 CEP/COS

11 JDMF

4 EU WC

8 KDMF

14 NDC API

19 Listed Suppliers

$ API Reference Price

INTERMEDIATES

5 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

40 FDF Dossiers

16 FDA Orange Book

12 Europe

2 Canada

4 South Africa

6 Listed Dossiers

RELATED EXCIPIENT COMPANIES

1 SPI Pharma

2 Seqens

4 DKSH

4 Faran Shimi Pharmaceutical

9 Gangwal Healthcare

3 Nanjing Well Pharmaceutical

1 ACG Worldwide

5 Actylis

6 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd

15 BASF

1 Clariant

10 Corel Pharma Chem

6 DFE Pharma

1 Finar

9 Gangwal Chemicals

5 Ideal Cures Pvt Ltd

1 Ingredion Pharma Solutions

35 Kerry

3 Kima Chemical

6 Lonza Capsugel

11 Microlex e.U

1 Nanjing Bold Chemical

2 Nomisma Healthcare

1 Novo Excipients

1 Pharmatrans-Sanaq

4 Pluviaendo

3 Prachin Chemical

1 Qianhao Chemical (Hebei) Co., Ltd

1 Qualicaps

10 Roquette

12 Seppic

4 Shanghai Shenmei Pharmaceutical Technology Co., Ltd

10 Sigachi Industries

2 The Dow Chemical Company

3 Vasa Pharmachem

EXCIPIENTS BY APPLICATIONS

49 Fillers, Diluents & Binders

46 Coating Systems & Additives

25 Controlled & Modified Release

24 Direct Compression

19 Thickeners and Stabilizers

17 Granulation

15 Disintegrants & Superdisintegrants

15 Solubilizers

13 Lubricants & Glidants

13 Co-Processed Excipients

12 Topical

11 Film Formers & Plasticizers

9 Parenteral

7 Emulsifying Agents

6 Taste Masking

5 Rheology Modifiers

5 Empty Capsules

5 API Stability Enhancers

5 Coloring Agents