Find Flurbiprofen Sodium manufacturers, exporters & distributors on PharmaCompass

PharmaCompass

Synopsis

Related ProductsRelated Products

Synopsis

ACTIVE PHARMA INGREDIENTS

0

CEP/COS

CEP/COS Certifications

0

JDMF

JDMFs Filed

0

NDC API

NDC API

0

VMF

NDC API

API REF. PRICE (USD/KG)

MARKET PLACE

0

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

0

Canada

Canada

0

Australia

Australia

0

South Africa

South Africa

0 DRUGS IN DEVELOPMENT

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

0

EDQM

0

JP

PATENTS & EXCLUSIVITIES

0

US Patents

0

US Exclusivities

0

Health Canada Patents

DIGITAL CONTENT

0

Data Compilation #PharmaFlow

0

Stock Recap #PipelineProspector

0

Weekly News Recap #Phispers

0

News #PharmaBuzz

GLOBAL SALES INFORMATION

Annual Reports

NA

Finished Drug Prices

NA

21 RELATED EXCIPIENT COMPANIES

28EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown
read-moreClick the button for full data set
Also known as: 56767-76-1, Sodium flurbiprofen, Ocufen, Sodium;2-(3-fluoro-4-phenylphenyl)propanoate, Flurbiprofen sodium?, M3qe6as001
Molecular Formula
C15H12FNaO2
Molecular Weight
266.24  g/mol
InChI Key
AUAGTGKMTMVIKN-UHFFFAOYSA-M
FDA UNII
M3QE6AS001

Flurbiprofen Sodium
An anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.
1 2D Structure

Flurbiprofen Sodium

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
sodium;2-(3-fluoro-4-phenylphenyl)propanoate
2.1.2 InChI
InChI=1S/C15H13FO2.Na/c1-10(15(17)18)12-7-8-13(14(16)9-12)11-5-3-2-4-6-11;/h2-10H,1H3,(H,17,18);/q;+1/p-1
2.1.3 InChI Key
AUAGTGKMTMVIKN-UHFFFAOYSA-M
2.1.4 Canonical SMILES
CC(C1=CC(=C(C=C1)C2=CC=CC=C2)F)C(=O)[O-].[Na+]
2.2 Other Identifiers
2.2.1 UNII
M3QE6AS001
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 2-fluoro-alpha-methyl-(1,1'-biphenyl)-4-acetic Acid

2. Ansaid

3. Apo Flurbiprofen

4. Apo-flurbiprofen

5. Bts 18322

6. Bts-18322

7. Bts18322

8. Cebutid

9. Dobrofen

10. E 7869

11. E-7869

12. E7869

13. Flubiprofen

14. Flugalin

15. Flurbiprofen

16. Fluriproben

17. Froben

18. Froben Sr

19. Neo Artrol

20. Novo Flurprofen

21. Novo-flurprofen

22. Nu Flurbiprofen

23. Nu-flurbiprofen

24. Ocufen

25. Ocuflur

26. Ratio Flurbiprofen

27. Ratio-flurbiprofen

28. Strefen

2.3.2 Depositor-Supplied Synonyms

1. 56767-76-1

2. Sodium Flurbiprofen

3. Ocufen

4. Sodium;2-(3-fluoro-4-phenylphenyl)propanoate

5. Flurbiprofen Sodium?

6. M3qe6as001

7. Flurbiprofen Sodium [usp]

8. Flurbiprofen Sodium Salt

9. Flurbiprofen Sodium Anhydrous

10. Einecs 260-373-2

11. Sodium 3-fluoro-4-phenylhydratropate

12. Unii-m3qe6as001

13. 2-fluoro-alpha-methyl-4-diphenylacetic Acid Sodium Salt

14. Sodium 2-fluoro-alpha-methyl-(1,1'-biphenyl)-4-acetate

15. Sodium 2-(2-fluorobiphenyl-4-yl)propanoate

16. Schembl4735171

17. Chembl1200990

18. Dtxsid80972216

19. (1,1'-biphenyl)-4-acetic Acid, 2-fluoro-alpha-methyl-, Sodium Salt

20. Flurbiprofen Sodium [who-dd]

21. Db-072190

22. (+/-)-flurbiprofen Sodium Anhydrous

23. Flurbiprofen Sodium Anhydrous, (+/-)-

24. Q27283443

25. Sodium2-(2-fluoro-[1,1'-biphenyl]-4-yl)propanoate

26. 2-(2-fluorobiphenyl-4-yl)propionic Acid Sodium Salt

27. 2-fluoro-.alpha.-methyl-4-diphenylacetic Acid Sodium Salt

28. (1,1'-biphenyl)-4-acetic Acid, 2-fluoro-.alpha.-methyl-, Sodium Salt (1:1)

2.4 Create Date
2008-02-05
3 Chemical and Physical Properties
Molecular Weight 266.24 g/mol
Molecular Formula C15H12FNaO2
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count3
Exact Mass266.07190207 g/mol
Monoisotopic Mass266.07190207 g/mol
Topological Polar Surface Area40.1 Ų
Heavy Atom Count19
Formal Charge0
Complexity292
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Drug and Medication Information
4.1 Drug Information
1 of 4  
Drug NameFlurbiprofen sodium
Drug LabelOCUFEN (flurbiprofen sodium ophthalmic solution, USP) 0.03% is a sterile topical nonsteroidal anti-inflammatory product for ophthalmic use. Chemical Name:Sodium ()-2-(2-fluoro-4-biphenylyl) propionate dihydrate. Structural Formula:C15H12FNaO22...
Active IngredientFlurbiprofen sodium
Dosage FormSolution/drops
RouteOphthalmic
Strength0.03%
Market StatusPrescription
CompanyBausch And Lomb

2 of 4  
Drug NameOcufen
PubMed HealthFlurbiprofen
Drug ClassesAnalgesic, Antirheumatic, Central Nervous System Agent, Musculoskeletal Agent, NSAID, Ophthalmologic Agent, Propionic Acid
Drug LabelOCUFEN (flurbiprofen sodium ophthalmic solution, USP) 0.03% is a sterile topical nonsteroidal anti-inflammatory product for ophthalmic use. Chemical Name:Sodium ()-2-(2-fluoro-4-biphenylyl) propionate dihydrate. Structural Formula:C15H12FNaO22...
Active IngredientFlurbiprofen sodium
Dosage FormSolution/drops
RouteOphthalmic
Strength0.03%
Market StatusPrescription
CompanyAllergan

3 of 4  
Drug NameFlurbiprofen sodium
Drug LabelOCUFEN (flurbiprofen sodium ophthalmic solution, USP) 0.03% is a sterile topical nonsteroidal anti-inflammatory product for ophthalmic use. Chemical Name:Sodium ()-2-(2-fluoro-4-biphenylyl) propionate dihydrate. Structural Formula:C15H12FNaO22...
Active IngredientFlurbiprofen sodium
Dosage FormSolution/drops
RouteOphthalmic
Strength0.03%
Market StatusPrescription
CompanyBausch And Lomb

4 of 4  
Drug NameOcufen
PubMed HealthFlurbiprofen
Drug ClassesAnalgesic, Antirheumatic, Central Nervous System Agent, Musculoskeletal Agent, NSAID, Ophthalmologic Agent, Propionic Acid
Drug LabelOCUFEN (flurbiprofen sodium ophthalmic solution, USP) 0.03% is a sterile topical nonsteroidal anti-inflammatory product for ophthalmic use. Chemical Name:Sodium ()-2-(2-fluoro-4-biphenylyl) propionate dihydrate. Structural Formula:C15H12FNaO22...
Active IngredientFlurbiprofen sodium
Dosage FormSolution/drops
RouteOphthalmic
Strength0.03%
Market StatusPrescription
CompanyAllergan

5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

Analgesics

Compounds capable of relieving pain without the loss of CONSCIOUSNESS. (See all compounds classified as Analgesics.)


Anti-Inflammatory Agents, Non-Steroidal

Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)


Cyclooxygenase Inhibitors

Compounds or agents that combine with cyclooxygenase (PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES) and thereby prevent its substrate-enzyme combination with arachidonic acid and the formation of eicosanoids, prostaglandins, and thromboxanes. (See all compounds classified as Cyclooxygenase Inhibitors.)


5.2 FDA Pharmacological Classification
5.2.1 Pharmacological Classes
Cyclooxygenase Inhibitors [MoA]; Nonsteroidal Anti-inflammatory Drug [EPC]; Anti-Inflammatory Agents, Non-Steroidal [CS]

API SUPPLIERS

read-more
read-more
Full Screen ViewFULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

USDMF

read-more
read-more

01

DDL Conference
Not Confirmed

01

DDL Conference
Not Confirmed

GDUFA

DMF Review : N/A

Rev. Date :

Pay. Date :

DMF Number : 10248

Submission : 1993-05-17

Status : Inactive

Type : II

blank

02

DDL Conference
Not Confirmed
Full Screen ViewFULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

API Reference Price

read-more
read-more
[{"dataSource":"API Export","activeIngredients":"FLURBIPROFEN SODIUM","year":"2021","qtr":"Q1","strtotime":1610562600,"product":"FLURBIPROFEN SODIUM BP\/USP (BATCH NO.029 G050 MFG DT. 07.2019 EXP DT 06.2024)","address":"142-48 S.V.ROAD,JOGESHWARI(W)","city":"MUMBAI, MAHARASHTRA","supplier":"FDC","supplierCountry":"INDIA","foreign_port":"LISBON","customer":"LABORATORIO EDOL PRODUTOS ","customerCountry":"PORTUGAL","quantity":"0.30","actualQuantity":"0.3","unit":"KGS","unitRateFc":"2604.2","totalValueFC":"791","currency":"USD","unitRateINR":192838.56666666668,"date":"14-Jan-2021","totalValueINR":"57851.57","totalValueInUsd":"791","indian_port":"BOMBAY AIR","hs_no":"29163190","bill_no":"7912945","productDescription":"API","marketType":"REGULATED MARKET","country":"PORTUGAL","selfForZScoreResived":"Pharma Grade","supplierPort":"BOMBAY AIR","supplierAddress":"142-48 S.V.ROAD,JOGESHWARI(W), MUMBAI, MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"FLURBIPROFEN SODIUM","year":"2021","qtr":"Q1","strtotime":1610908200,"product":"FLURBIPROFEN SODIUM USP (BATCH NO.029K04 3 MFG DT. 11.2019 EXP DT 10.2024)","address":"142-48 S.V.ROAD,JOGESHWARI(W)","city":"MUMBAI, MAHARASHTRA","supplier":"FDC","supplierCountry":"INDIA","foreign_port":"LAHORE","customer":"HABIB BANK LIMITED","customerCountry":"PAKISTAN","quantity":"0.25","actualQuantity":"0.25","unit":"KGS","unitRateFc":"3806.1","totalValueFC":"963.4","currency":"USD","unitRateINR":281842.71999999997,"date":"18-Jan-2021","totalValueINR":"70460.68","totalValueInUsd":"963.4","indian_port":"BOMBAY AIR","hs_no":"29163190","bill_no":"7987152","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"PAKISTAN","selfForZScoreResived":"Pharma Grade","supplierPort":"BOMBAY AIR","supplierAddress":"142-48 S.V.ROAD,JOGESHWARI(W), MUMBAI, MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q1","strtotime":1675276200,"product":"FLURBIPROFEN SODIUM BP\/USP (BATCH NO. 0","address":"142-48,,S.V.ROAD, JOGESHWARI WEST","city":"MUMBAI,MAHARASHTRA","supplier":"FDC","supplierCountry":"INDIA","foreign_port":"LISBON","customer":"LABORATORIO EDOL PRODUTOS ","customerCountry":"PORTUGAL","quantity":"0.50","actualQuantity":"0.5","unit":"KGS","unitRateFc":"3000","totalValueFC":"1380.3","currency":"USD","unitRateINR":228000,"date":"02-Feb-2023","totalValueINR":"114000","totalValueInUsd":"1380.3","indian_port":"BOMBAY AIR","hs_no":"29163190","bill_no":"7485606","productDescription":"API","marketType":"REGULATED MARKET","country":"PORTUGAL","selfForZScoreResived":"Pharma Grade","supplierPort":"BOMBAY AIR","supplierAddress":"142-48,,S.V.ROAD, JOGESHWARI WEST, MUMBAI,MAHARASHTRA","customerAddress":""}]
14-Jan-2021
02-Feb-2023
KGS
overview
Loading...

Average Price (USD/KGS)

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country Total Quantity
(KGS)
Average Price
(USD/KGS)
Number of Transactions

Upgrade, download data, analyse, strategize, subscribe with us contact

Related Excipient Companies

Upload your portfolio for free, ask us

Excipients by Applications

Click here to find the perfect excipient manufacturers by their capabilities

Coating Systems & Additives

read-more
read-more

Parenteral

read-more
read-more

Controlled & Modified Release

read-more
read-more

Topical

read-more
read-more

Fillers, Diluents & Binders

read-more
read-more

Disintegrants & Superdisintegrants

read-more
read-more

API Stability Enhancers

read-more
read-more

Global Sales Information

Do you need Business Intel? Ask us

Market Place

Do you need sourcing support? Ask us

REF. STANDARDS & IMPURITIES

Upload your portfolio for free, ask us

ANALYTICAL

Upload your methods for free, ask us

ABOUT THIS PAGE

Ask Us for Pharmaceutical Supplier and Partner
Ask Us, Find A Supplier / Partner
No Commissions, No Strings Attached, Get Connected for FREE

What are you looking for?

How can we help you?

The request can't be empty

Please read our Privacy Policy carefully

You must agree to the privacy policy

The name can't be empty
The company can't be empty.
The email can't be empty Please enter a valid email.
The mobile can't be empty