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Flurogestone Acetate

Polfa Tarchomin is a leading Polish pharmaceutical company with 200 year tradition in manufacture and sale of pharmaceutical products.

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ACTIVE PHARMA INGREDIENTS

1 API Suppliers, 1 Listed Suppliers

1 API Suppliers
1 Listed Suppliers

Synopsis

ACTIVE PHARMA INGREDIENTS

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Chemistry

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Also known as: 2529-45-5, Flugestone 17-acetate, Fluorogestone acetate, Flugestone acetate, Flurogestone acetate [usan], Sc-9880

Molecular Formula

C₂₃H₃₁FO₅

Molecular Weight

406.5 g/mol

InChI Key

JKQQZJHNUVDHKP-FQJIPJFPSA-N

FDA UNII

X60881643X

A synthetic fluorinated steroid that is used as a progestational hormone.

1 2D Structure

Flurogestone Acetate

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

[(8S,9R,10S,11S,13S,14S,17R)-17-acetyl-9-fluoro-11-hydroxy-10,13-dimethyl-3-oxo-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl] acetate

2.1.2 InChI

InChI=1S/C23H31FO5/c1-13(25)22(29-14(2)26)10-8-17-18-6-5-15-11-16(27)7-9-20(15,3)23(18,24)19(28)12-21(17,22)4/h11,17-19,28H,5-10,12H2,1-4H3/t17-,18-,19-,20-,21-,22-,23-/m0/s1

2.1.3 InChI Key

JKQQZJHNUVDHKP-FQJIPJFPSA-N

2.1.4 Canonical SMILES

CC(=O)C1(CCC2C1(CC(C3(C2CCC4=CC(=O)CCC43C)F)O)C)OC(=O)C

2.1.5 Isomeric SMILES

CC(=O)[C@]1(CC[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2CCC4=CC(=O)CC[C@@]43C)F)O)C)OC(=O)C

2.2 Other Identifiers

2.2.1 UNII

X60881643X

2.3 Synonyms

2.3.1 MeSH Synonyms

1. 17 Beta Acetoxy 9 Fluoro 11 Beta Hydroxyprogesterone

2. 17 Beta-acetoxy-9-fluoro-11 Beta-hydroxyprogesterone

3. Acetate, Flugestone

4. Acetate, Fluorogestone

5. Acetate, Flurogestone

6. Beta-acetoxy-9-fluoro-11 Beta-hydroxyprogesterone, 17

7. Beta-hydroxyprogesterone, 17 Beta-acetoxy-9-fluoro-11

8. Cronolone

9. Flugestone

10. Flugestone Acetate

11. Fluorogestone Acetate

12. Flurogestone

2.3.2 Depositor-Supplied Synonyms

1. 2529-45-5

2. Flugestone 17-acetate

3. Fluorogestone Acetate

4. Flugestone Acetate

5. Flurogestone Acetate [usan]

6. Sc-9880

7. Pregn-4-ene-3,20-dione, 17-(acetyloxy)-9-fluoro-11-hydroxy-, (11b)-

8. [(8s,9r,10s,11s,13s,14s,17r)-17-acetyl-9-fluoro-11-hydroxy-10,13-dimethyl-3-oxo-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl] Acetate

9. Chebi:79932

10. Nsc-65411

11. Gyncro-mate

12. 9-fluoro-11beta,17-dihydroxypregn-4-ene-3,20-dione 17-acetate

13. X60881643x

14. Flurogestone Acetate (usan)

15. Synchro-mate

16. Fga

17. Fluorogesterone Acetate

18. Nsc 65411

19. Unii-x60881643x

20. Ncgc00160534-01

21. Einecs 219-776-9

22. Brn 3123549

23. Dsstox_cid_26210

24. Dsstox_rid_81438

25. Dsstox_gsid_46210

26. 4-08-00-02904 (beilstein Handbook Reference)

27. Schembl281972

28. 9alpha-fluoro-11-hydroxy,17alpha-acetoxy Progesterone

29. Chembl2106773

30. Dtxsid6046210

31. Flurogestone Acetate [mi]

32. Flugestone Acetate [mart.]

33. Zinc4213372

34. Tox21_111878

35. Akos015896293

36. Pregn-4-ene-3,20-dione, 17-(acetyloxy)-9-fluoro-11-hydroxy-, (11.beta.)-

37. Am84839

38. Flurogestone Acetate [green Book]

39. Cas-2529-45-5

40. D04235

41. 529f455

42. A817767

43. Q5462900

44. 9alpha-fluoro-11-hydroxy,17alpha-acetoxyprogesterone

45. (11beta)17-(acetyloxy)-9-fluoro-11-hydroxypregn-4-ene-3,20-dione

46. 9-fluoro-11.beta.,17-dihydroxypregn-4-ene-3,20-dione 17-acetate

47. Pregn-4-ene-3,20-dione, 17-(acetyloxy)-9-fluoro-11-hydroxy-, (11beta)-

48. Pregn-4-ene-3,20-dione, 9-fluoro-11-beta,17-dihydroxy-, 17-acetate

49. [(8s,9r,10s,11s,13s,14s,17r)-17-ethanoyl-9-fluoranyl-10,13-dimethyl-11-oxidanyl-3-oxidanylidene-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl] Ethanoate

50. Acetic Acid [(8s,9r,10s,11s,13s,14s,17r)-17-acetyl-9-fluoro-11-hydroxy-10,13-dimethyl-3-oxo-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl] Ester

2.4 Create Date

2006-10-25

3 Chemical and Physical Properties

Molecular Formula	C₂₃H₃₁FO₅
Molecular Weight	406.5 g/mol
XLogP3	2.3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	3
Exact Mass	406.21555225 g/mol
Monoisotopic Mass	406.21555225 g/mol
Topological Polar Surface Area	80.7 Å²
Heavy Atom Count	29
Formal Charge	0
Complexity	820
Isotope Atom Count	0
Defined Atom Stereocenter Count	7
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Progestins

Compounds that interact with PROGESTERONE RECEPTORS in target tissues to bring about the effects similar to those of PROGESTERONE. Primary actions of progestins, including natural and synthetic steroids, are on the UTERUS and the MAMMARY GLAND in preparation for and in maintenance of PREGNANCY. (See all compounds classified as Progestins.)

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ABOUT THIS PAGE

Flurogestone Acetate Manufacturers

A Flurogestone Acetate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Flurogestone Acetate, including repackagers and relabelers. The FDA regulates Flurogestone Acetate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Flurogestone Acetate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Flurogestone Acetate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Flurogestone Acetate Suppliers

A Flurogestone Acetate supplier is an individual or a company that provides Flurogestone Acetate active pharmaceutical ingredient (API) or Flurogestone Acetate finished formulations upon request. The Flurogestone Acetate suppliers may include Flurogestone Acetate API manufacturers, exporters, distributors and traders.

click here to find a list of Flurogestone Acetate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Flurogestone Acetate GMP

Flurogestone Acetate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Flurogestone Acetate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Flurogestone Acetate GMP manufacturer or Flurogestone Acetate GMP API supplier for your needs.

Flurogestone Acetate CoA

A Flurogestone Acetate CoA (Certificate of Analysis) is a formal document that attests to Flurogestone Acetate's compliance with Flurogestone Acetate specifications and serves as a tool for batch-level quality control.

Flurogestone Acetate CoA mostly includes findings from lab analyses of a specific batch. For each Flurogestone Acetate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Flurogestone Acetate may be tested according to a variety of international standards, such as European Pharmacopoeia (Flurogestone Acetate EP), Flurogestone Acetate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Flurogestone Acetate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.