DRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

Contact Supplier

Valsynthese, part of the SSE Group, is a CDMO focused on highly energetic and highly hazardous chemistry.

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

DIGITAL CONTENT

1 NEWS #PharmaBuzz

media
1 NEWS #PharmaBuzz

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: Qc4g8xs0h0, Fosravuconazole (l-lysine ethanolate), Fosravuconazole l-lysine ethanolate [mi], ((1r,2r)-2-(4-(4-cyanophenyl)-2-thiazolyl)-1-(2,4-difluorophenyl)-1-(1h-1,2,4-triazol-1-ylmethyl)propoxy) methyl ester compound with lysine, ethanolate (1:1:1), L-lysine, compd. with 4-(2-((1r,2r)-2-(2,4-difluorophenyl)-1-methyl-2-((phosphonooxy)methoxy)-3-(1h-1,2,4-triazol-1-yl)propyl)-4-thiazolyl)benzonitrile and ethanol (1:1:1), Fosravuconazole l-lysine ethanolate (jan)

Molecular Formula

C₃₁H₄₀F₂N₇O₈PS

Molecular Weight

739.7 g/mol

InChI Key

VOWYGLHOVNSCSA-NRVKWRQJSA-N

FDA UNII

QC4G8XS0H0

1 2D Structure

VOWYGLHOVNSCSA-NRVKWRQJSA-N

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

[(2R,3R)-3-[4-(4-cyanophenyl)-1,3-thiazol-2-yl]-2-(2,4-difluorophenyl)-1-(1,2,4-triazol-1-yl)butan-2-yl]oxymethyl dihydrogen phosphate;(2S)-2,6-diaminohexanoic acid;ethanol

2.1.2 InChI

InChI=1S/C23H20F2N5O5PS.C6H14N2O2.C2H6O/c1-15(22-29-21(10-37-22)17-4-2-16(9-26)3-5-17)23(11-30-13-27-12-28-30,34-14-35-36(31,32)33)19-7-6-18(24)8-20(19)25;7-4-2-1-3-5(8)6(9)10;1-2-3/h2-8,10,12-13,15H,11,14H2,1H3,(H2,31,32,33);5H,1-4,7-8H2,(H,9,10);3H,2H2,1H3/t15-,23+;5-;/m00./s1

2.1.3 InChI Key

VOWYGLHOVNSCSA-NRVKWRQJSA-N

2.1.4 Canonical SMILES

CCO.CC(C1=NC(=CS1)C2=CC=C(C=C2)C#N)C(CN3C=NC=N3)(C4=C(C=C(C=C4)F)F)OCOP(=O)(O)O.C(CCN)CC(C(=O)O)N

2.1.5 Isomeric SMILES

CCO.C[C@@H](C1=NC(=CS1)C2=CC=C(C=C2)C#N)[C@](CN3C=NC=N3)(C4=C(C=C(C=C4)F)F)OCOP(=O)(O)O.C(CCN)C[C@@H](C(=O)O)N

2.2 Other Identifiers

2.2.1 UNII

QC4G8XS0H0

2.3 Synonyms

2.3.1 MeSH Synonyms

1. F-rvcz

2.3.2 Depositor-Supplied Synonyms

1. Qc4g8xs0h0

2. Fosravuconazole (l-lysine Ethanolate)

3. Fosravuconazole L-lysine Ethanolate [mi]

4. ((1r,2r)-2-(4-(4-cyanophenyl)-2-thiazolyl)-1-(2,4-difluorophenyl)-1-(1h-1,2,4-triazol-1-ylmethyl)propoxy) Methyl Ester Compound With Lysine, Ethanolate (1:1:1)

5. L-lysine, Compd. With 4-(2-((1r,2r)-2-(2,4-difluorophenyl)-1-methyl-2-((phosphonooxy)methoxy)-3-(1h-1,2,4-triazol-1-yl)propyl)-4-thiazolyl)benzonitrile And Ethanol (1:1:1)

6. Fosravuconazole L-lysine Ethanolate (jan)

7. Fosravuconazole L-lysine Ethanolate [jan]

8. 914361-45-8

9. L-lysine, Compd. With 4-[2-[(1r,2r)-2-(2,4-difluorophenyl)-1-methyl-2-[(phosphonooxy)methoxy]-3-(1h-1,2,4-triazol-1-yl)propyl]-4-thiazolyl]benzonitrile And Ethanol (1:1:1)

10. Unii-qc4g8xs0h0

11. E-1224 L-lysine Ethanolate

12. Bms-379224 L-lysine Ethanolate

13. Hy-16779b

14. Cs-0145609

15. D10762

16. Fosravuconazole L-lysine Ethanolate [who-dd]

17. (s)-2,6-diaminohexanoic Acid (((2r,3r)-3-(4-(4-cyanophenyl)thiazol-2-yl)-2-(2,4-difluorophenyl)-1-(1h-1,2,4-triazol-1-yl)butan-2-yl)oxy)methyl Dihydrogen Phosphate And Ethanol Salt

2.4 Create Date

2016-01-22

3 Chemical and Physical Properties

Molecular Formula	C₃₁H₄₀F₂N₇O₈PS
Molecular Weight	739.7 g/mol
Hydrogen Bond Donor Count	6
Hydrogen Bond Acceptor Count	17
Rotatable Bond Count	15
Exact Mass	739.23647576 g/mol
Monoisotopic Mass	739.23647576 g/mol
Topological Polar Surface Area	281 Å²
Heavy Atom Count	50
Formal Charge	0
Complexity	967
Isotope Atom Count	0
Defined Atom Stereocenter Count	3
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	3