Interquim comes from an international group of 50 companies active in the pharma, hospital, diagnostics, fine chemicals & feed sectors.

Virtual Booth

Contact Supplier

Rusan Pharma: Over 30 years of specializing in the treatment of Addiction and Pain Management.

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

DEVELOPMENTS

2 Drugs in Development

2 Drugs in Development

DIGITAL CONTENT

1 NEWS #PharmaBuzz

media
1 NEWS #PharmaBuzz

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

2DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: 1259933-16-8, Funapide, (+)-, Xen402, Xen-401-s, Tv-45070, A5595lhj2l

Molecular Formula

C₂₂H₁₄F₃NO₅

Molecular Weight

429.3 g/mol

InChI Key

NEBUOXBYNAHKFV-NRFANRHFSA-N

FDA UNII

A5595LHJ2L

Funapide has been used in trials studying the treatment of Pharmacokinetics, Postherpetic Neuralgia, and Osteoarthritis of the Knee.

1 2D Structure

Funapide

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(7S)-1'-[[5-(trifluoromethyl)furan-2-yl]methyl]spiro[6H-furo[2,3-f][1,3]benzodioxole-7,3'-indole]-2'-one

2.1.2 InChI

InChI=1S/C22H14F3NO5/c23-22(24,25)19-6-5-12(31-19)9-26-15-4-2-1-3-13(15)21(20(26)27)10-28-16-8-18-17(7-14(16)21)29-11-30-18/h1-8H,9-11H2/t21-/m0/s1

2.1.3 InChI Key

NEBUOXBYNAHKFV-NRFANRHFSA-N

2.1.4 Canonical SMILES

C1C2(C3=CC=CC=C3N(C2=O)CC4=CC=C(O4)C(F)(F)F)C5=CC6=C(C=C5O1)OCO6

2.1.5 Isomeric SMILES

C1[C@]2(C3=CC=CC=C3N(C2=O)CC4=CC=C(O4)C(F)(F)F)C5=CC6=C(C=C5O1)OCO6

2.2 Other Identifiers

2.2.1 UNII

A5595LHJ2L

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Tv-45070

2. Xen402

2.3.2 Depositor-Supplied Synonyms

1. 1259933-16-8

2. Funapide, (+)-

3. Xen402

4. Xen-401-s

5. Tv-45070

6. A5595lhj2l

7. (3's)-1'-[[5-(trifluoromethyl)-2-furanyl]methyl]spiro[furo[2,3-f]-1,3-benzodioxole-7(6h),3'-[3h]indol]-2'(1'h)-one

8. Xen-402

9. Xpf-002

10. (7s)-1'-{[5-(trifluoromethyl)furan-2-yl]methyl}spiro[furo[2,3-f][1,3]benzodioxole-7,3'-indol]-2'(1'h)-one

11. Spiro[furo[2,3-f]-1,3-benzodioxole-7(6h),3'-[3h]indol]-2'(1'h)-one, 1'-[[5-(trifluoromethyl)-2-furanyl]methyl]-, (3's)-

12. (3's)-1'-((5-(trifluoromethyl)furan-2-yl)methyl)-2h,6h-spiro(furo(2,3-f)(1,3)benzodioxole-7,3'-indol)-2'(1'h)-one

13. Spiro(furo(2,3-f)-1,3-benzodioxole-7(6h),3'-(3h)indol)-2'(1'h)-one, 1'-((5-(trifluoromethyl)-2-furanyl)methyl)-, (3's)-

14. Funapide [inn]

15. (3's)-1'-{[5-(trifluoromethyl)furan-2-yl]methyl}-2h,6h-spiro[furo[2,3-f][1,3]benzodioxole-7,3'-indol]-2'(1'h)-one

16. Funapide [usan:inn]

17. Unii-a5595lhj2l

18. Funapide; Xen402

19. Funapide [usan]

20. Funapide (usan/inn)

21. Funapide [who-dd]

22. Schembl1612849

23. Chembl3707218

24. Bdbm206760

25. Ex-a2684

26. Mfcd28502435

27. Akos030228679

28. Zinc113473392

29. Db11769

30. Sb18915

31. Hy-16723

32. Us9260446, (i-s)

33. Cs-0012323

34. J3.591.370j

35. D11156

36. Q18393205

37. (3s)-1-[[5-(trifluoromethyl)-2-furanyl]methyl]spiro[furo[2,3-f]-1,3-benzodioxole-7(6h),3-[3h]indol]-2(1h)-one

38. (3s)-1-[5-(trifluoromethyl)-2-furanylmethyl]spiro[indoline-3,7'(6'h)-furo[2,3-f]-1,3-benzodioxole]-2-one

39. (7s)-1'-[[5-(trifluoromethyl)furan-2-yl]methyl]spiro[6h-furo[2,3-f][1,3]benzodioxole-7,3'-indole]-2'-one

40. (7s)-1'-{[5-(trifluoromethyl)furan-2-yl]methyl}spiro-[furo[2,3-f][1,3]benzodioxole-7,3'-indol]-2'(1'h)-one

41. (s)-1'-((5-(trifluoromethyl)furan-2-yl)methyl)-6h-spiro[[1,3]dioxolo[4,5-f]benzofuran-7,3'-indolin]-2'-one

2.4 Create Date

2011-01-17

3 Chemical and Physical Properties

Molecular Formula	C₂₂H₁₄F₃NO₅
Molecular Weight	429.3 g/mol
XLogP3	3.5
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	2
Exact Mass	429.08240703 g/mol
Monoisotopic Mass	429.08240703 g/mol
Topological Polar Surface Area	61.1 Å²
Heavy Atom Count	31
Formal Charge	0
Complexity	734
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1