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ACTIVE PHARMA INGREDIENTS

2 API Suppliers, 2 Listed Suppliers

2 API Suppliers
2 Listed Suppliers

DEVELOPMENTS

1 Drugs in Development

1 Drugs in Development

FINISHED DOSAGE FORMULATIONS

3 FDF Dossiers, 3 Listed Dossiers

3 FDF Dossiers
3 Listed Dossiers

MARKET PLACE

2 APIs, 1 FDF Dossiers

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2 APIs
1 FDF Dossiers

ANALYTICAL

1 BioAnalytical Methods

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1 BioAnalytical Methods

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

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FDA Orange Book

Europe

Canada

Australia

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DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

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USP

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US Patents

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Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

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Weekly News Recap #Phispers

News #PharmaBuzz

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Chemistry

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Also known as: Furazidin, 1672-88-4, Furazidine, Akritoin, Furaginum, 1-((3-(5-nitro-2-furyl)allylidene)amino)hydantoin

Molecular Formula

C₁₀H₈N₄O₅

Molecular Weight

264.19 g/mol

InChI Key

DECBQELQORZLLP-UAIOPKHMSA-N

FDA UNII

K2R4N34Y9I

Nitrofuran derivative anti-infective agent used for urinary tract infections.

1 2D Structure

Furazidin

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

1-[(E)-[(E)-3-(5-nitrofuran-2-yl)prop-2-enylidene]amino]imidazolidine-2,4-dione

2.1.2 InChI

InChI=1S/C10H8N4O5/c15-8-6-13(10(16)12-8)11-5-1-2-7-3-4-9(19-7)14(17)18/h1-5H,6H2,(H,12,15,16)/b2-1+,11-5+

2.1.3 InChI Key

DECBQELQORZLLP-UAIOPKHMSA-N

2.1.4 Canonical SMILES

C1C(=O)NC(=O)N1N=CC=CC2=CC=C(O2)[N+](=O)[O-]

2.1.5 Isomeric SMILES

C1C(=O)NC(=O)N1/N=C/C=C/C2=CC=C(O2)[N+](=O)[O-]

2.2 Other Identifiers

2.2.1 UNII

K2R4N34Y9I

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Furazidin

2. Solafur

2.3.2 Depositor-Supplied Synonyms

1. Furazidin

2. 1672-88-4

3. Furazidine

4. Akritoin

5. Furaginum

6. 1-((3-(5-nitro-2-furyl)allylidene)amino)hydantoin

7. 1-[(e)-[(e)-3-(5-nitrofuran-2-yl)prop-2-enylidene]amino]imidazolidine-2,4-dione

8. K2r4n34y9i

9. Nf 416

10. F-35

11. 1-((3-(5-nitro-2-furyl)allylidene)amino)-hydantoin

12. 1-[(e)-[(z)-3-(5-nitrofuran-2-yl)prop-2-enylidene]amino]imidazolidine-2,4-dione

13. Furamag

14. 1-((3-(5-nitrofuran-2-yl)allylidene)-amino)imidazolidine-2,4-dione

15. 1-(((1e,2e)-3-(5-nitrofuran-2-yl)allylidene)amino)imidazolidine-2,4-dione

16. 1-{[(1e,2e)-3-(5-nitrofuran-2-yl)prop-2-en-1-ylidene]amino}imidazolidine-2,4-dione

17. Ccris 1199

18. 1-(3-(5-nitro-2-furyl)-n-2-propenylidine)amino-hydantoin

19. Brn 0307076

20. Unii-k2r4n34y9i

21. Furagin (tn)

22. Furazidin [mart.]

23. Furazidin [who-dd]

24. 1-[3-(5-nitro-2-furyl)allylidenamino]hydantoin

25. 4-24-00-01048 (beilstein Handbook Reference)

26. Schembl3194895

27. Chembl3707254

28. Hydantoin, 1-((3-(5-nitro-2-furyl)allylidene)amino)-

29. Schembl17292896

30. J01xe03

31. Dtxsid101030908

32. Ex-a1974

33. Bdbm50549808

34. S3709

35. Stk368597

36. Zinc31430194

37. 1-((3-(5-nitro-2-furanyl)-2-propenylidene)amino)-4-imidazolidinedione

38. 2,4-imidazolidinedione, 1-((3-(5-nitro-2-furanyl)-2-propenylidene)amino)-

39. Akos005444359

40. Ccg-267084

41. Cs-0798

42. Db13475

43. Bs-49182

44. Hy-77036

45. D07998

46. 672f884

47. A810846

48. 1-(3-(5-nitro-2-furyl)-n-2-propenylidine)aminohydantoin

49. 1-(((e)-3-(5-nitrofuran-2-yl)prop-2-enylidene)amino)imidazolidine-2,4-dione

50. 2,4-imidazolidinedione, 1-[[3-(5-nitro-2-furanyl)-2-propen-1-ylidene]amino]-

2.4 Create Date

2006-07-03

3 Chemical and Physical Properties

Molecular Formula	C₁₀H₈N₄O₅
Molecular Weight	264.19 g/mol
XLogP3	0.5
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	3
Exact Mass	264.04946937 g/mol
Monoisotopic Mass	264.04946937 g/mol
Topological Polar Surface Area	121 Å²
Heavy Atom Count	19
Formal Charge	0
Complexity	455
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	2
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Anti-Infective Agents, Urinary

Substances capable of killing agents causing urinary tract infections or of preventing them from spreading. (See all compounds classified as Anti-Infective Agents, Urinary.)

4.2 ATC Code

J - Antiinfectives for systemic use

J01 - Antibacterials for systemic use

J01X - Other antibacterials

J01XE - Nitrofuran derivatives

J01XE03 - Furazidin

API SUPPLIERS

01

Olpha

Latvia

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Medlab Asia & Asia Health

Not Confirmed

Olpha, a JSC AB City subsidiary, is a leading Baltic firm with 50 years of experience in medicines & chemical pharmaceuticals.

Contact Supplier

Latvia

Virtual Booth

Digital Content

USDMF CEP/COS JDMF EU-WC NDC KDMF VMF ASMF

AUDIT

02

Menadiona

Spain

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Medlab Asia & Asia Health

Not Confirmed

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Listed Suppliers

01

Olpha

Latvia

Medlab Asia & Asia Health

Not Confirmed

Olpha, a JSC AB City subsidiary, is a leading Baltic firm with 50 years of experience in medicines & chemical pharmaceuticals.

Contact Supplier

Latvia

Virtual Booth

Digital Content

Furazidin

About the Company : Olpha, the subsidiary of JSC AB City, is one of the largest companies in the Baltic states with 50 years of experience in the production of medicines & chemical pharmaceutical prod...

Olpha, the subsidiary of JSC AB City, is one of the largest companies in the Baltic states with 50 years of experience in the production of medicines & chemical pharmaceutical products. The range of product portfolio developed by the company, includes 60 formulations, 25 APIs & >20 intermediates, including medicinal products for the nervous system, cardiovascular health, as well as antiviral, antibacterial & anti-allergic drugs. The health care products created by Olpha ensure both, the even more broader access of users to the necessary medicinal products, as well as the company’s growth & reputation in the global market.