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0 DRUGS IN DEVELOPMENT

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Stock Recap #PipelineProspector

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GLOBAL SALES INFORMATION

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3 RELATED EXCIPIENT COMPANIES

4EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as:
Molecular Formula
C18H31GdN4O9
Molecular Weight
604.7  g/mol
InChI Key
ZPDFIIGFYAHNSK-FUISWZMFSA-K

Gadobutrol
1 2D Structure

Gadobutrol

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-[4,10-bis(carboxylatomethyl)-7-[(2R)-1,3,4-trihydroxybutan-2-yl]-1,4,7,10-tetrazacyclododec-1-yl]acetate;gadolinium(3+)
2.1.2 InChI
InChI=1S/C18H34N4O9.Gd/c23-12-14(15(25)13-24)22-7-5-20(10-17(28)29)3-1-19(9-16(26)27)2-4-21(6-8-22)11-18(30)31;/h14-15,23-25H,1-13H2,(H,26,27)(H,28,29)(H,30,31);/q;+3/p-3/t14-,15?;/m1./s1
2.1.3 InChI Key
ZPDFIIGFYAHNSK-FUISWZMFSA-K
2.1.4 Canonical SMILES
C1CN(CCN(CCN(CCN1CC(=O)[O-])CC(=O)[O-])C(CO)C(CO)O)CC(=O)[O-].[Gd+3]
2.1.5 Isomeric SMILES
C1CN(CCN(CCN(CCN1CC(=O)[O-])CC(=O)[O-])[C@H](CO)C(CO)O)CC(=O)[O-].[Gd+3]
2.2 Create Date
2012-03-21
3 Chemical and Physical Properties
Molecular Weight 604.7 g/mol
Molecular Formula C18H31GdN4O9
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count13
Rotatable Bond Count2
Exact Mass605.13321 g/mol
Monoisotopic Mass605.13321 g/mol
Topological Polar Surface Area194 A^2
Heavy Atom Count32
Formal Charge0
Complexity555
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2

API SUPPLIERS

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USDMF

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01

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothBiophore is a research-driven global pharmaceutical company focused on niche APIs for the generic industry.

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Digital Content Digital Content

GDUFA

DMF Review : Complete

Rev. Date : 2020-08-04

Pay. Date : 2020-06-23

DMF Number : 33420

Submission : 2019-09-10

Status : Active

Type : II

Biophore

02

Bayer Ag

Germany

USDMF

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euroPLX 86 Munich
Not Confirmed

02

Bayer Ag

Germany
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euroPLX 86 Munich
Not Confirmed

GDUFA

DMF Review : N/A

Rev. Date :

Pay. Date :

DMF Number : 13061

Submission : 1998-07-07

Status : Active

Type : II

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03

euroPLX 86 Munich
Not Confirmed

03

euroPLX 86 Munich
Not Confirmed

GDUFA

DMF Review : N/A

Rev. Date :

Pay. Date :

DMF Number : 40533

Submission : 2024-09-23

Status : Active

Type : II

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04

euroPLX 86 Munich
Not Confirmed

05

euroPLX 86 Munich
Not Confirmed

05

euroPLX 86 Munich
Not Confirmed

GDUFA

DMF Review : Complete

Rev. Date : 2024-01-08

Pay. Date : 2023-12-13

DMF Number : 39149

Submission : 2023-11-30

Status : Active

Type : II

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06

euroPLX 86 Munich
Not Confirmed

06

euroPLX 86 Munich
Not Confirmed

GDUFA

DMF Review : Complete

Rev. Date : 2020-06-19

Pay. Date : 2020-04-29

DMF Number : 34832

Submission : 2020-05-28

Status : Active

Type : II

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07

euroPLX 86 Munich
Not Confirmed

07

euroPLX 86 Munich
Not Confirmed

GDUFA

DMF Review : Complete

Rev. Date : 2023-09-25

Pay. Date : 2023-08-29

DMF Number : 36996

Submission : 2022-03-31

Status : Active

Type : II

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08

euroPLX 86 Munich
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09

St Pharm Co Ltd

South Korea

USDMF

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euroPLX 86 Munich
Not Confirmed

09

St Pharm Co Ltd

South Korea
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euroPLX 86 Munich
Not Confirmed

GDUFA

DMF Review : Complete

Rev. Date : 2021-03-30

Pay. Date : 2021-02-26

DMF Number : 35662

Submission : 2021-02-26

Status : Active

Type : II

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10

euroPLX 86 Munich
Not Confirmed

10

euroPLX 86 Munich
Not Confirmed

GDUFA

DMF Review : Complete

Rev. Date : 2024-08-09

Pay. Date : 2024-07-25

DMF Number : 39094

Submission : 2023-11-24

Status : Active

Type : II

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API Reference Price

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04-Feb-2021
24-Sep-2024
KGS
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