Find Galantamine Benzoate manufacturers, exporters & distributors on PharmaCompass

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Chemistry

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Also known as: Gln-1062, 224169-27-1, Galantamine benzoate, Xoi2q0zf7g, 6h-benzofuro(3a,3,2-ef)(2)benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, benzoate (ester), (4as,6r,8as)-, Benzgalantamine
Molecular Formula
C24H25NO4
Molecular Weight
391.5  g/mol
InChI Key
JKVNJTYHRABHIY-WXVUKLJWSA-N
FDA UNII
XOI2Q0ZF7G

Galantamine Benzoate
1 2D Structure

Galantamine Benzoate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
[(1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraen-14-yl] benzoate
2.1.2 InChI
InChI=1S/C24H25NO4/c1-25-13-12-24-11-10-18(28-23(26)16-6-4-3-5-7-16)14-20(24)29-22-19(27-2)9-8-17(15-25)21(22)24/h3-11,18,20H,12-15H2,1-2H3/t18-,20-,24-/m0/s1
2.1.3 InChI Key
JKVNJTYHRABHIY-WXVUKLJWSA-N
2.1.4 Canonical SMILES
CN1CCC23C=CC(CC2OC4=C(C=CC(=C34)C1)OC)OC(=O)C5=CC=CC=C5
2.1.5 Isomeric SMILES
CN1CC[C@@]23C=C[C@@H](C[C@@H]2OC4=C(C=CC(=C34)C1)OC)OC(=O)C5=CC=CC=C5
2.2 Other Identifiers
2.2.1 UNII
XOI2Q0ZF7G
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Gln-1062

2.3.2 Depositor-Supplied Synonyms

1. Gln-1062

2. 224169-27-1

3. Galantamine Benzoate

4. Xoi2q0zf7g

5. 6h-benzofuro(3a,3,2-ef)(2)benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, Benzoate (ester), (4as,6r,8as)-

6. Benzgalantamine

7. Unii-xoi2q0zf7g

8. Benzgalantamine [inn]

9. Schembl16885442

10. [(1s,12s,14r)-9-methoxy-4-methyl-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraen-14-yl] Benzoate

11. Gln 1062

12. Cs-6749

13. Hy-101710

2.4 Create Date
2009-10-26
3 Chemical and Physical Properties
Molecular Weight 391.5 g/mol
Molecular Formula C24H25NO4
XLogP34.1
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count4
Exact Mass391.17835828 g/mol
Monoisotopic Mass391.17835828 g/mol
Topological Polar Surface Area48 Ų
Heavy Atom Count29
Formal Charge0
Complexity645
Isotope Atom Count0
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

API SUPPLIERS

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01

GLP Bio

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Medlab Asia & Asia Health
Not Confirmed
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GLP Bio

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Medlab Asia & Asia Health
Not Confirmed
USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
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02

FandaChem

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Medlab Asia & Asia Health
Not Confirmed
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FandaChem

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Medlab Asia & Asia Health
Not Confirmed
USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
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03

Axon Medchem

Netherlands

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Medlab Asia & Asia Health
Not Confirmed
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Axon Medchem

Netherlands

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Medlab Asia & Asia Health
Not Confirmed
USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
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04

Haoyuan Chemexpress Co.Ltd

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Medlab Asia & Asia Health
Not Confirmed
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NDC API

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01

Medlab Asia & Asia Health
Not Confirmed
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Medlab Asia & Asia Health
Not Confirmed

GALANTAMINE BENZOATE GLUCONATE

NDC Package Code : 65129-2455

Start Marketing Date : 2021-02-24

End Marketing Date : 2024-12-31

Dosage Form (Strength) : POWDER (1kg/kg)

Marketing Category : BULK INGREDIENT

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Drugs in Development

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Details:

The Company intends to use the proceeds towards the commercialization and launch of Zunveyl (benzgalantamine) for the treatment of mild-to-moderate Alzheimer’s Disease.


Lead Product(s): Galantamine Benzoate

Therapeutic Area: Neurology Brand Name: Zunveyl

Study Phase: ApprovedProduct Type: Small molecule

Sponsor: Titan Partners Group

Deal Size: $50.0 million Upfront Cash: Undisclosed

Deal Type: Public Offering November 12, 2024

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01

Medlab Asia & Asia Health
Not Confirmed
Medlab Asia & Asia Health
Not Confirmed

Details : The Company intends to use the proceeds towards the commercialization and launch of Zunveyl (benzgalantamine) for the treatment of mild-to-moderate Alzheimer’s Disease.

Brand Name : Zunveyl

Molecule Type : Small molecule

Upfront Cash : Undisclosed

November 12, 2024

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Details:

The proceeds from the financing will be utilized to continue commercialization work for the Company’s recently approved Zunveyl (benzgalantamine), indicated for the treatment of Alzheimer's disease.


Lead Product(s): Galantamine Benzoate

Therapeutic Area: Neurology Brand Name: Zunveyl

Study Phase: ApprovedProduct Type: Small molecule

Sponsor: The Benchmark Company, LLC

Deal Size: $4.5 million Upfront Cash: Undisclosed

Deal Type: Financing September 24, 2024

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02

Medlab Asia & Asia Health
Not Confirmed
Medlab Asia & Asia Health
Not Confirmed

Details : The proceeds from the financing will be utilized to continue commercialization work for the Company’s recently approved Zunveyl (benzgalantamine), indicated for the treatment of Alzheimer's disease.

Brand Name : Zunveyl

Molecule Type : Small molecule

Upfront Cash : Undisclosed

September 24, 2024

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Details:

ZUNVEYL, a prodrug of AD treatment galantamine and an acetylcholinesterase inhibitor (AChEI), is postulated to exert its therapeutic effect by preventing the breakdown of acetylcholine.


Lead Product(s): Galantamine Benzoate

Therapeutic Area: Neurology Brand Name: Zunveyl

Study Phase: ApprovedProduct Type: Small molecule

Sponsor: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable July 29, 2024

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03

Medlab Asia & Asia Health
Not Confirmed
Medlab Asia & Asia Health
Not Confirmed

Details : ZUNVEYL, a prodrug of AD treatment galantamine and an acetylcholinesterase inhibitor (AChEI), is postulated to exert its therapeutic effect by preventing the breakdown of acetylcholine.

Brand Name : Zunveyl

Molecule Type : Small molecule

Upfront Cash : Not Applicable

July 29, 2024

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Details:

The company expects to use the net proceeds for research and development of ALPHA-1062 (benzgalantamine), a prodrug of an approved acetylcholinesterase inhibitor (AChEI) for the treatment of Alzheimer's Disease.


Lead Product(s): Galantamine Benzoate

Therapeutic Area: Neurology Brand Name: ALPHA-1062

Study Phase: Phase IIIProduct Type: Small molecule

Sponsor: Undisclosed

Deal Size: $6.5 million Upfront Cash: Undisclosed

Deal Type: Public Offering December 22, 2023

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04

Medlab Asia & Asia Health
Not Confirmed
Medlab Asia & Asia Health
Not Confirmed

Details : The company expects to use the net proceeds for research and development of ALPHA-1062 (benzgalantamine), a prodrug of an approved acetylcholinesterase inhibitor (AChEI) for the treatment of Alzheimer's Disease.

Brand Name : ALPHA-1062

Molecule Type : Small molecule

Upfront Cash : Undisclosed

December 22, 2023

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Details:

ALPHA-1062 (benzgalantamine), AChE inhibitor delayed-release oral tablet formulation. Currently being evaluated in the Phase III clinical trial studies for the treatment of mild-to-moderate Alzheimer’s Disease.


Lead Product(s): Galantamine Benzoate

Therapeutic Area: Neurology Brand Name: ALPHA-1062

Study Phase: Phase IIIProduct Type: Small molecule

Sponsor: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable December 07, 2023

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05

Medlab Asia & Asia Health
Not Confirmed
Medlab Asia & Asia Health
Not Confirmed

Details : ALPHA-1062 (benzgalantamine), AChE inhibitor delayed-release oral tablet formulation. Currently being evaluated in the Phase III clinical trial studies for the treatment of mild-to-moderate Alzheimer’s Disease.

Brand Name : ALPHA-1062

Molecule Type : Small molecule

Upfront Cash : Not Applicable

December 07, 2023

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Details:

The company expects to use the net proceeds for research and development of ALPHA-1062 (benzgalantamine), a prodrug of an approved acetylcholinesterase inhibitor (AChEI) for the treatment of Alzheimer's Disease.


Lead Product(s): Galantamine Benzoate

Therapeutic Area: Neurology Brand Name: ALPHA-1062

Study Phase: Phase IIIProduct Type: Small molecule

Sponsor: Undisclosed

Deal Size: $6.5 million Upfront Cash: Undisclosed

Deal Type: Private Placement December 04, 2023

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06

Medlab Asia & Asia Health
Not Confirmed
Medlab Asia & Asia Health
Not Confirmed

Details : The company expects to use the net proceeds for research and development of ALPHA-1062 (benzgalantamine), a prodrug of an approved acetylcholinesterase inhibitor (AChEI) for the treatment of Alzheimer's Disease.

Brand Name : ALPHA-1062

Molecule Type : Small molecule

Upfront Cash : Undisclosed

December 04, 2023

blank

Details:

The company expects to use the net proceeds for research and development of ALPHA-1062 (benzgalantamine), a prodrug of an approved acetylcholinesterase inhibitor (AChEI) for the treatment of Alzheimer's Disease.


Lead Product(s): Galantamine Benzoate

Therapeutic Area: Neurology Brand Name: ALPHA-1062

Study Phase: Phase IIIProduct Type: Small molecule

Sponsor: Spartan Capital Securities

Deal Size: $6.5 million Upfront Cash: Undisclosed

Deal Type: Private Placement November 08, 2023

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07

Medlab Asia & Asia Health
Not Confirmed
Medlab Asia & Asia Health
Not Confirmed

Details : The company expects to use the net proceeds for research and development of ALPHA-1062 (benzgalantamine), a prodrug of an approved acetylcholinesterase inhibitor (AChEI) for the treatment of Alzheimer's Disease.

Brand Name : ALPHA-1062

Molecule Type : Small molecule

Upfront Cash : Undisclosed

November 08, 2023

blank

Details:

The Company expects to use the net proceeds for research and development of ALPHA-1062 (benzgalantamine), a prodrug of an approved acetylcholinesterase inhibitor (AChEI) for the treatment of Alzheimer's Disease.


Lead Product(s): Galantamine Benzoate

Therapeutic Area: Neurology Brand Name: ALPHA-1062

Study Phase: Phase IIIProduct Type: Small molecule

Sponsor: Undisclosed

Deal Size: $97.8 million Upfront Cash: Undisclosed

Deal Type: Private Placement October 16, 2023

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08

Medlab Asia & Asia Health
Not Confirmed
Medlab Asia & Asia Health
Not Confirmed

Details : The Company expects to use the net proceeds for research and development of ALPHA-1062 (benzgalantamine), a prodrug of an approved acetylcholinesterase inhibitor (AChEI) for the treatment of Alzheimer's Disease.

Brand Name : ALPHA-1062

Molecule Type : Small molecule

Upfront Cash : Undisclosed

October 16, 2023

blank

Details:

ALPHA-1062, a proprietary, patented, delayed release oral tablet formulation in development for the treatment of mild-to-moderate Alzheimer’s Disease.


Lead Product(s): Galantamine Benzoate

Therapeutic Area: Neurology Brand Name: ALPHA-1062

Study Phase: Phase IIIProduct Type: Small molecule

Sponsor: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 27, 2023

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09

Medlab Asia & Asia Health
Not Confirmed
Medlab Asia & Asia Health
Not Confirmed

Details : ALPHA-1062, a proprietary, patented, delayed release oral tablet formulation in development for the treatment of mild-to-moderate Alzheimer’s Disease.

Brand Name : ALPHA-1062

Molecule Type : Small molecule

Upfront Cash : Not Applicable

September 27, 2023

blank

Details:

The Company expects to use the net proceeds for research and development of ALPHA-1062 (benzgalantamine), a prodrug of an approved acetylcholinesterase inhibitor (AChEI) for the treatment of Alzheimer's Disease.


Lead Product(s): Galantamine Benzoate

Therapeutic Area: Neurology Brand Name: ALPHA-1062

Study Phase: Phase IIIProduct Type: Small molecule

Sponsor: Undisclosed

Deal Size: $1.3 million Upfront Cash: Undisclosed

Deal Type: Private Placement August 31, 2023

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10

Medlab Asia & Asia Health
Not Confirmed
Medlab Asia & Asia Health
Not Confirmed

Details : The Company expects to use the net proceeds for research and development of ALPHA-1062 (benzgalantamine), a prodrug of an approved acetylcholinesterase inhibitor (AChEI) for the treatment of Alzheimer's Disease.

Brand Name : ALPHA-1062

Molecule Type : Small molecule

Upfront Cash : Undisclosed

August 31, 2023

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