Synopsis
Synopsis
0
CEP/COS
0
JDMF
0
EU WC
0
KDMF
0
NDC API
0
VMF
0
Listed Suppliers
0
FDF
0
FDF Dossiers
0
FDA Orange Book
0
Europe
0
Canada
0
Australia
0
South Africa
0
Listed Dossiers
DRUG PRODUCT COMPOSITIONS
0
EDQM
0
USP
0
JP
0
Others
0
US Patents
0
US Exclusivities
0
Health Canada Patents
0
Data Compilation #PharmaFlow
0
Stock Recap #PipelineProspector
0
Weekly News Recap #Phispers
US Medicaid
NA
Annual Reports
NA
Finished Drug Prices
NA
1. 13450-90-3
2. Trichlorogallane
3. Trichlorogallium
4. Gallium Chloride (gacl3)
5. Gallium(3+) Chloride
6. Gacl3
7. Gallium(iii) Chloride Solution
8. Mfcd00011018
9. Gallium(iii) Chloride, Ultra Dry
10. Ccris 4492
11. Hsdb 6445
12. Einecs 236-610-0
13. Nsc 94002
14. Gallium Chloride, Gacl3
15. Wln: Ga G3
16. Unii-4y6gqd4915
17. Dtxsid8031360
18. Gallium(iii) Chloride Anhydrous
19. Gallium (iii) Chloride, Anhydrous
20. Nsc94002
21. Gallium(iii) Chloride, Anhydrous Lump
22. Gallium(iii) Chloride, Anhydrous, Beads,
23. Gallium(iii) Chloride, Anhydrous, Granular
24. Cs-0085456
25. D90758
26. Q31153
27. Gallium(iii) Chloride Solution, 0.5 M In Pentane
28. Gallium(iii) Chloride Beads, Anhydrous, =99.999% Trace Metals Basis
29. Gallium(iii) Chloride, Beads, Anhydrous, >=99.999% Trace Metals Basis
30. Gallium(iii) Chloride, Anhydrous, Beads, -10 Mesh, 99.99% Trace Metals Basis
| Molecular Weight | 176.08 g/mol |
|---|---|
| Molecular Formula | Cl3Ga |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 0 |
| Rotatable Bond Count | 0 |
| Exact Mass | 173.83213 g/mol |
| Monoisotopic Mass | 173.83213 g/mol |
| Topological Polar Surface Area | 0 Ų |
| Heavy Atom Count | 4 |
| Formal Charge | 0 |
| Complexity | 8 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
The gastrointestinal absorption of cationic gallium salts in mammals is less than 1% for physiologic doses ... /due/ to the hydrolysis of the Ga+3 salts to insoluble and unabsorbable gallium hydroxide Ga(OH)3. /Gallium salts/
Venugopal, B. and T.D. Luckey. Metal Toxicity in Mammals, 2. New York: Plenum Press, 1978., p. 113
Following inhalation of gallium trichloride aerosols containing 0.125-0.25 mg Ga/liter, gallium is retained in the alveoli and not absorbed. There are no reports of absorption of gallium through the skin. ... Parenterally injected gallium compounds are excreted mainly in the urine; only about 7.8% of a dose of gallium trichloride and 3.3% of a dose of gallium citrate are excreted in the feces.
Venugopal, B. and T.D. Luckey. Metal Toxicity in Mammals, 2. New York: Plenum Press, 1978., p. 114
Feeding GaCl3 at dietary levels of 10, 100, 500, and 1000 ppm as gallium for 26 weeks, however, resulted in no discernible toxic response in rats; no gallium could be found in the soft tissues, and traces in bone indicated negligible absorption.
Clayton, G.D., F.E. Clayton (eds.) Patty's Industrial Hygiene and Toxicology. Volumes 2A, 2B, 2C, 2D, 2E, 2F: Toxicology. 4th ed. New York, NY: John Wiley & Sons Inc., 1993-1994., p. 2009
Rats fed gallium trichloride at dietary levels of 500 or 10000 ppm gallium for 26 weeks exhibited no observable toxic symptoms. Autopsy revealed no gallium in soft tissues and only minute traces in bone. However, parenterally injected gallium salts showed variation in the toxicity levels (LD50 values) in different species, depending upon the mode of administration. ... Intravenous admin of gallium trichloride ... was highly toxic, and sometimes immediately lethal, because of colloidal gallium hydroxide Ga(OH)3 formation in the blood.
Venugopal, B. and T.D. Luckey. Metal Toxicity in Mammals, 2. New York: Plenum Press, 1978., p. 114
There are no reports of any evidence for the presence of a homeostatic mechanism for gallium in mammals.
Venugopal, B. and T.D. Luckey. Metal Toxicity in Mammals, 2. New York: Plenum Press, 1978., p. 114
Digital Content 
NEWS #PharmaBuzz
Market Place
ABOUT THIS PAGE
LOOKING FOR A SUPPLIER?
