menu
    • menu

    Find Gallium Citrate GA-67 manufacturers, exporters & distributors on PharmaCompass

    Suanfarma, at the Core of a Better Life.

    Virtual Booth

    Contact Supplier

    Bloomage is a one-stop source for CEP Sodium Hyaluronate and Hyaluronic Acid// FDA-inspected & GMP-certified.

    Virtual Booth

    Contact Supplier

    Egis is a Hungarian generic pharma company with 110 years history. Our activities incorporate all areas of the pharma value chain.

    Virtual Booth

    Contact Supplier

    Rochem, your partner in developing, sourcing, and supplying pharmaceutical & animal health ingredients of Chinese origin.

    Virtual Booth

    Contact Supplier

    Transo-Pharm GmbH works globally to supply Active Pharmaceutical Ingredients adhering to the highest quality & GMP standards.

    Virtual Booth

    Contact Supplier

    xyz-pharma-m-2025-01-20

    Virtual Booth

    Contact Supplier

    ACTIVE PHARMA INGREDIENTS

    FINISHED DOSAGE FORMULATIONS

    RELATED EXCIPIENT COMPANIES

    EXCIPIENTS BY APPLICATIONS

    DIGITAL CONTENT

    PharmaCompass

    Synopsis

    Product SearchProduct Search

    Synopsis

    ACTIVE PHARMA INGREDIENTS

    1

    API Suppliers

    API Suppliers

    1

    USDMF

    US DMFs Filed

    0

    CEP/COS

    CEP/COS Certifications

    0

    JDMF

    JDMFs Filed

    0

    EU WC

    EU WC

    0

    KDMF

    KDMF

    0

    NDC API

    NDC API

    0

    VMF

    NDC API

    0

    Listed Suppliers

    Other Suppliers

    API REF. PRICE (USD/KG)

    $
    $ 0

    MARKET PLACE

    0

    API

    0

    FDF

    0INTERMEDIATES

    FINISHED DOSAGE FORMULATIONS

    6

    FDF Dossiers

    FDF Dossiers

    4

    FDA Orange Book

    FDA (Orange Book)

    1

    Europe

    Europe

    1

    Canada

    Canada

    0

    Australia

    Australia

    0

    South Africa

    South Africa

    0

    Listed Dossiers

    Listed Dossiers

    0 DRUGS IN DEVELOPMENT

    FDF Dossiers

    DRUG PRODUCT COMPOSITIONS

    REF. STANDARDS OR IMPURITIES

    0

    EDQM

    0

    USP

    0

    JP

    0

    Others

    PATENTS & EXCLUSIVITIES

    0

    US Patents

    0

    US Exclusivities

    0

    Health Canada Patents

    DIGITAL CONTENT

    1

    Data Compilation #PharmaFlow

    0

    Stock Recap #PipelineProspector

    0

    Weekly News Recap #Phispers

    0

    News #PharmaBuzz

    GLOBAL SALES INFORMATION

    US Medicaid

    NA

    Annual Reports

    NA

    Finished Drug Prices

    NA

    8 RELATED EXCIPIENT COMPANIES

    9EXCIPIENTS BY APPLICATIONS

    Chemistry

    Click the arrow to open the dropdown
    read-moreClick the button for full data set
    read-moreClick the button for full data set
    Also known as: Gallium citrate ga 67, Gallium-67 citrate, Gallium (67 ga) citrate, 41183-64-6, Gallium (67ga) citrate, Gallium-(sup 67)ga citrate (1:1)
    Molecular Formula
    C6H5GaO7
    Molecular Weight
    256.03  g/mol
    InChI Key
    YEEGWNXDUZONAA-RYDPDVNUSA-K
    FDA UNII
    4LJK511Z86
    Gallium Citrate GA-67
    Gallium Citrate Ga-67 is the citrate salt of the radioisotope gallium Ga 67. Although the mechanism is unknown, gallium Ga 67 concentrates in lysosomes and is bound to a soluble intracellular protein in certain viable primary and metastatic tumors and focal sites of inflammation, allowing scintigraphic localization. Ga-67 scintigraphy (GS) cannot differentiate between tumor and acute inflammation.
    Gallium citrate ga-67 is a Radioactive Diagnostic Agent. The mechanism of action of gallium citrate ga-67 is as a Radiopharmaceutical Activity.
    1 2D Structure

    Gallium Citrate GA-67

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    gallium-67(3+);2-hydroxypropane-1,2,3-tricarboxylate
    2.1.2 InChI
    InChI=1S/C6H8O7.Ga/c7-3(8)1-6(13,5(11)12)2-4(9)10;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);/q;+3/p-3/i;1-3
    2.1.3 InChI Key
    YEEGWNXDUZONAA-RYDPDVNUSA-K
    2.1.4 Canonical SMILES
    C(C(=O)[O-])C(CC(=O)[O-])(C(=O)[O-])O.[Ga+3]
    2.1.5 Isomeric SMILES
    C(C(=O)[O-])C(CC(=O)[O-])(C(=O)[O-])O.[67Ga+3]
    2.2 Other Identifiers
    2.2.1 UNII
    4LJK511Z86
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 67ga Radioisotope

    2. Ga-67 Radioisotope

    3. Gallium-67

    2.3.2 Depositor-Supplied Synonyms

    1. Gallium Citrate Ga 67

    2. Gallium-67 Citrate

    3. Gallium (67 Ga) Citrate

    4. 41183-64-6

    5. Gallium (67ga) Citrate

    6. Gallium-(sup 67)ga Citrate (1:1)

    7. Neoscan

    8. Gallium ((sup 67)ga) Citrate

    9. Gallium (67ga) Citrate [inn]

    10. 4ljk511z86

    11. 1,2,3-propanetricarboxylic Acid, 2-hydroxy-, Gallium-(sup 67)ga (1:1) Salt

    12. Gallium (67ga) Citrate (inn)

    13. (67-ga)gallium Citrate

    14. Gallium Citrate (ga67)

    15. Einecs 255-248-4

    16. Gallii (67 Ga) Citras

    17. Gallii (67 Ga) Citras [inn-latin]

    18. Citrato De Galio (67 Ga)

    19. Citrate De Gallium (67 Ga)

    20. Unii-4ljk511z86

    21. Citrato De Galio (67 Ga) [inn-spanish]

    22. Citrate De Gallium (67 Ga) [inn-french]

    23. Gallium Citrate, Ga-67

    24. 67ga Radioisotope

    25. Neoscan (tn)

    26. Ga-67 Radioisotope

    27. Gallium 67 Citrate

    28. Gallium Citrate,ga-67

    29. Gallium Ga-67 Citrate

    30. Gallium Citrate Ga 67 [usan:usp:jan]

    31. Gallium Citrate (67 Ga)

    32. Schembl9754280

    33. Gallium Citrate Ga 67 (usp)

    34. Gallium-67ga Citrate (1:1)

    35. Gallium-67(3+); 2-hydroxypropane-1,2,3-tricarboxylate

    36. Chebi:31645

    37. Dtxsid70194107

    38. Gallium Citrate Ga 67 [mi]

    39. Db06784

    40. Gallium Citrate Ga 67 [usan]

    41. Gallium Citrate,ga-67 [vandf]

    42. Gallium (67ga) Citrate [who-dd]

    43. Gallium (67ga) Citrate Injection (jp17)

    44. Gallium Citrate Ga-67 [orange Book]

    45. Gallium Citrate Ga 67 [usp Impurity]

    46. D01936

    47. Q27260007

    48. 1,2,3-propanetricarboxylic Acid, 2-hydroxy-, Gallium-67ga (1:1) Salt

    2.4 Create Date
    2005-06-24
    3 Chemical and Physical Properties
    Molecular Weight 256.03 g/mol
    Molecular Formula C6H5GaO7
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count7
    Rotatable Bond Count2
    Exact Mass255.93173 g/mol
    Monoisotopic Mass255.93173 g/mol
    Topological Polar Surface Area141 Ų
    Heavy Atom Count14
    Formal Charge0
    Complexity211
    Isotope Atom Count1
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Drug and Medication Information
    4.1 Drug Indication

    Gallium Citrate Ga 67 Injection may be useful to demonstrate the presence and extent of Hodgkin's disease, lymphoma, and bronchogenic carcinoma. Positive gallium Ga-67 uptake in the absence of prior symptoms warrants follow-up as an indication of a potential disease state. Gallium Citrate Ga 67 Injection may be useful as an aid in detecting some acute inflammatory lesions.

    5 Pharmacology and Biochemistry
    5.1 Pharmacology

    It has been reported in the scientific literature that following intravenous injection, the highest tissue concentration of gallium Ga-67 - other than tumors and sites of infection - is the renal cortex. After the first day, the maximum concentration shifts to bone and lymph nodes and after the first week, to liver and spleen. Gallium Ga-67 is excreted relatively slowly from the body. The average whole body retention is 65 percent after seven days, with 26 percent having been excreted in the urine and 9 percent in the stools.

    5.2 FDA Pharmacological Classification
    5.2.1 Active Moiety
    GALLIUM CITRATE GA-67
    5.2.2 FDA UNII
    4LJK511Z86
    5.2.3 Pharmacological Classes
    Mechanisms of Action [MoA] - Radiopharmaceutical Activity
    5.3 ATC Code

    V - Various

    V09 - Diagnostic radiopharmaceuticals

    V09H - Inflammation and infection detection

    V09HX - Other diagnostic radiopharmaceuticals for inflammation and infection detection

    V09HX01 - Gallium (67Ga) citrate

    5.4 Absorption, Distribution and Excretion

    Absorption

    The body generally handles Ga3+ as though it were ferric iron (Fe-III). However, gallium can not be reduced in vivo. Therefore, ferric ion is easily reduced and interacts with protoporphyrin IX to form heme, gallium remains bound to iron-transport proteins and carrier molecules.

    Route of Elimination

    No urinary excretion; elimination primarily via fecal excretion.

    5.5 Biological Half-Life

    78.26 hours

    5.6 Mechanism of Action

    Gallium Citrate Ga 67, with no carrier added, has been found to concentrate in certain viable primary and metastatic tumors as well as focal sites of infection. The body generally handles Ga3+ as though it were ferric iron (Fe-III), and thus the free isotope ion is bound (and concentrates) in areas of inflammation, such as an infection site, and also areas of rapid cell division. Ga-67 binds to transferrin, leukocyte lactoferrin, bacterial siderophores, inflammatory proteins, and cell-membranes in neutrophils, both living and dead. Lactoferrin is contained within leukocytes. Ga-67 may bind to lactoferrin and be transported to sites of inflammation, or binds to lactoferrin released during bacterial phagocytosis at infection sites (and remains due to binding with macrophage receptors). Ga-67 also attaches to the siderophore molecules of bacteria themselves, and for this reason can be used in leukopenic patients with bacterial infection (here it attaches directly to bacterial proteins, and leukocytes are not needed). Uptake is thought to be associated with a range of tumour properties including transferring receptors, anaerobic tumor metabolism and tumor perfusion and vascular permeability.

    Related Excipient Companies

    Upload your portfolio for free, ask us

    Excipients by Applications

    Click here to find the perfect excipient manufacturers by their capabilities

    Parenteral

    read-more
    read-more

    Topical

    read-more
    read-more

    Controlled & Modified Release

    read-more
    read-more

    Solubilizers

    read-more
    read-more

    Digital Content read-more

    Create Content with PharmaCompass, ask us

    DATA COMPILATION #PharmaFlow

    read-more
    read-more

    ABOUT THIS PAGE

    Gallium Citrate GA-67 Manufacturers

    A Gallium Citrate GA-67 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Gallium Citrate GA-67, including repackagers and relabelers. The FDA regulates Gallium Citrate GA-67 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Gallium Citrate GA-67 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    Gallium Citrate GA-67 Suppliers

    A Gallium Citrate GA-67 supplier is an individual or a company that provides Gallium Citrate GA-67 active pharmaceutical ingredient (API) or Gallium Citrate GA-67 finished formulations upon request. The Gallium Citrate GA-67 suppliers may include Gallium Citrate GA-67 API manufacturers, exporters, distributors and traders.

    click here to find a list of Gallium Citrate GA-67 suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Gallium Citrate GA-67 USDMF

    A Gallium Citrate GA-67 DMF (Drug Master File) is a document detailing the whole manufacturing process of Gallium Citrate GA-67 active pharmaceutical ingredient (API) in detail. Different forms of Gallium Citrate GA-67 DMFs exist exist since differing nations have different regulations, such as Gallium Citrate GA-67 USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Gallium Citrate GA-67 DMF submitted to regulatory agencies in the US is known as a USDMF. Gallium Citrate GA-67 USDMF includes data on Gallium Citrate GA-67's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Gallium Citrate GA-67 USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Gallium Citrate GA-67 suppliers with USDMF on PharmaCompass.

    Gallium Citrate GA-67 GMP

    Gallium Citrate GA-67 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Gallium Citrate GA-67 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Gallium Citrate GA-67 GMP manufacturer or Gallium Citrate GA-67 GMP API supplier for your needs.

    Gallium Citrate GA-67 CoA

    A Gallium Citrate GA-67 CoA (Certificate of Analysis) is a formal document that attests to Gallium Citrate GA-67's compliance with Gallium Citrate GA-67 specifications and serves as a tool for batch-level quality control.

    Gallium Citrate GA-67 CoA mostly includes findings from lab analyses of a specific batch. For each Gallium Citrate GA-67 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Gallium Citrate GA-67 may be tested according to a variety of international standards, such as European Pharmacopoeia (Gallium Citrate GA-67 EP), Gallium Citrate GA-67 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Gallium Citrate GA-67 USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
    Ask Us for Pharmaceutical Supplier and Partner
    Ask Us, Find A Supplier / Partner
    No Commissions, No Strings Attached, Get Connected for FREE

    What are you looking for?

    How can we help you?

    The request can't be empty

    Please read our Privacy Policy carefully

    You must agree to the privacy policy

    The name can't be empty
    The company can't be empty.
    The email can't be empty Please enter a valid email.
    The mobile can't be empty

    Market Place

    Market Place

    PharmaCompass

    Home

    Market Place

    Menu

    Post Enquiry

    Post Enquiry

    Market Place

    Market Place

    Search