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Chemistry

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Also known as: Garamycin solution, Gentimicin sulfate solution, Gentamicin sulfate, 500x solution, Akos015895526, G0383
Molecular Formula
C21H45N5O11S
Molecular Weight
575.7  g/mol
InChI Key
NWQISSNHRDDWRM-UHFFFAOYSA-N

Gentamicin Sulfate
1 2D Structure

Gentamicin Sulfate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-[4,6-diamino-3-[3-amino-6-[1-(methylamino)ethyl]oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol;sulfuric acid
2.1.2 InChI
InChI=1S/C21H43N5O7.H2O4S/c1-9(25-3)13-6-5-10(22)19(31-13)32-16-11(23)7-12(24)17(14(16)27)33-20-15(28)18(26-4)21(2,29)8-30-20;1-5(2,3)4/h9-20,25-29H,5-8,22-24H2,1-4H3;(H2,1,2,3,4)
2.1.3 InChI Key
NWQISSNHRDDWRM-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC(C1CCC(C(O1)OC2C(CC(C(C2O)OC3C(C(C(CO3)(C)O)NC)O)N)N)N)NC.OS(=O)(=O)O
2.2 Synonyms
2.2.1 Depositor-Supplied Synonyms

1. Garamycin Solution

2. Gentimicin Sulfate Solution

3. Gentamicin Sulfate, 500x Solution

4. Akos015895526

5. G0383

2.3 Create Date
2009-08-08
3 Chemical and Physical Properties
Molecular Weight 575.7 g/mol
Molecular Formula C21H45N5O11S
Hydrogen Bond Donor Count10
Hydrogen Bond Acceptor Count16
Rotatable Bond Count7
Exact Mass575.28362844 g/mol
Monoisotopic Mass575.28362844 g/mol
Topological Polar Surface Area283 Ų
Heavy Atom Count38
Formal Charge0
Complexity717
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count13
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Drug and Medication Information
4.1 Drug Information
1 of 2  
Drug NameGenoptic
PubMed HealthGentamicin
Drug ClassesAntibacterial, Antibiotic
Active IngredientGentamicin sulfate
Dosage FormSolution/drops
RouteOphthalmic
Strengtheq 0.3% base
Market StatusPrescription
CompanyAllergan

2 of 2  
Drug NameGenoptic
PubMed HealthGentamicin
Drug ClassesAntibacterial, Antibiotic
Active IngredientGentamicin sulfate
Dosage FormSolution/drops
RouteOphthalmic
Strengtheq 0.3% base
Market StatusPrescription
CompanyAllergan

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04-Jan-2021
15-Jul-2024
KGS
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DOSAGE - SUSPENSION/DROPS;OPHTHALMIC - EQ 0.3...DOSAGE - SUSPENSION/DROPS;OPHTHALMIC - EQ 0.3% BASE;1%

USFDA APPLICATION NUMBER - 50586

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DOSAGE - OINTMENT;OPHTHALMIC - EQ 0.3% BASE;0...DOSAGE - OINTMENT;OPHTHALMIC - EQ 0.3% BASE;0.6%

USFDA APPLICATION NUMBER - 50612

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