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Chemistry

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Also known as: Gentisic acid, 490-79-9, Benzoic acid, 2,5-dihydroxy-, Hydroquinonecarboxylic acid, 5-hydroxysalicylic acid, Gentisate
Molecular Formula
C7H6O4
Molecular Weight
154.12  g/mol
InChI Key
WXTMDXOMEHJXQO-UHFFFAOYSA-N
FDA UNII
VP36V95O3T

Gentisic Acid
2,5-dihydroxybenzoic acid is a natural product found in Persicaria mitis, Tilia tomentosa, and other organisms with data available.
1 2D Structure

Gentisic Acid

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2,5-dihydroxybenzoic acid
2.1.2 InChI
InChI=1S/C7H6O4/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,8-9H,(H,10,11)
2.1.3 InChI Key
WXTMDXOMEHJXQO-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1=CC(=C(C=C1O)C(=O)O)O
2.2 Other Identifiers
2.2.1 UNII
VP36V95O3T
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 2,5-dihydroxybenzoate

2. 2,5-dihydroxybenzoic Acid, Monosodium Salt

3. Gentisic Acid

4. Lithium 2,5-dihydroxybenzoate

2.3.2 Depositor-Supplied Synonyms

1. Gentisic Acid

2. 490-79-9

3. Benzoic Acid, 2,5-dihydroxy-

4. Hydroquinonecarboxylic Acid

5. 5-hydroxysalicylic Acid

6. Gentisate

7. Gensigen

8. Gensigon

9. 2,5-dioxybenzoic Acid

10. 2,5-dhba

11. Gentisinic Acid

12. Salicylic Acid, 5-hydroxy-

13. Carboxyhydroquinone

14. Kyselina Gentisinova

15. Gentisic Acid [inn]

16. Gentisinate

17. Nsc 27224

18. Kyselina 2,5-dihydroxybenzoova

19. Benzoic Acid,2,5-dihydroxy

20. Mfcd00002460

21. 3,6-dihydroxybenzoic Acid

22. Chembl1461

23. Vp36v95o3t

24. Chebi:17189

25. Gentinatre

26. Gentalpin

27. Gentasol

28. Gentidol

29. Gentisan

30. Gentisod

31. Legential

32. Nagentis

33. Casate

34. Gabail

35. Nagent

36. Casate Sodium

37. Nsc-27224

38. Gensalate Sodium

39. Sodium-gent

40. Wln: Qvr Bq Eq

41. Gentisate Sodium

42. Acido Gentisico

43. Acide Gentisique

44. Acidum Gentisicum

45. Kyselina Gentisinova [czech]

46. Nsc8512

47. Acide Gentisique [inn-french]

48. Acido Gentisico [inn-spanish]

49. Acidum Gentisicum [inn-latin]

50. Einecs 207-718-5

51. Acido 2,5-diidrossibenzoico [italian]

52. 2,5-dihydroxy Benzoic Acid

53. Brn 2209119

54. Gentisicacid

55. Kyselina 2,5-dihydroxybenzoova [czech]

56. Acido 2,5-diidrossibenzoico

57. Unii-vp36v95o3t

58. Ai3-60431

59. Dihydroxybenzoicacid

60. Gtq

61. 2,5-dioxybenzoate

62. Genop

63. 5-hydroxy-salicylate

64. 3,6-dihydroxybenzoate

65. Gentisinic Acid Polymer

66. Spectrum_001241

67. 2,5dihydroxybenzoic Acid

68. 5-hydroxy-salicylic Acid

69. Spectrum2_000773

70. Spectrum3_001326

71. Spectrum4_001821

72. Spectrum5_000581

73. 2,5,dihydroxybenzoic Acid

74. Bmse000326

75. Gentisic Acid [ii]

76. Gentisic Acid [mi]

77. Schembl3690

78. 2,5-dihydroxy-benzoic Acid

79. 2,5-dihydroxybenzoate, Vi

80. Nciopen2_000913

81. Oprea1_039290

82. Bspbio_003051

83. Kbiogr_002487

84. Kbioss_001721

85. 4-10-00-01441 (beilstein Handbook Reference)

86. Mls002207134

87. Divk1c_000538

88. Spbio_000846

89. Zinc1507

90. Gentisic Acid [who-dd]

91. Dtxsid4060078

92. Hms501k20

93. Kbio1_000538

94. Kbio2_001721

95. Kbio2_004289

96. Kbio2_006857

97. Kbio3_002271

98. Ninds_000538

99. 2,5-dihydroxybenzoic Acid, 98%

100. Amy18270

101. Nsc27224

102. Nsc49098

103. Bbl013232

104. Bdbm50335808

105. Ccg-40154

106. Ck2181

107. Nsc-49098

108. S3799

109. Stk426343

110. Akos003267857

111. Cs-w001179

112. Hy-w001179

113. Ps-6232

114. Idi1_000538

115. Ncgc00178325-01

116. 2,5-dihydroxybenzoic Acid [inci]

117. Ac-23625

118. Smr000393742

119. Sy014321

120. Gentisic Acid (2,5-dihydroxybenzoic Acid)

121. Db-051598

122. Mesalazine Impurity G [ep Impurity]

123. D0569

124. D2933

125. Ft-0610382

126. Ft-0667079

127. En300-81715

128. 2,5-dihydroxybenzoic Acid, Analytical Standard

129. C00628

130. Ae-562/40605400

131. Q417831

132. Resorcyllic Acid, Alphaodium 2,5-dihydroxybenzoate

133. W-106033

134. 26a2cd0f-7ebd-431f-8bda-168766205ae1

135. Z275164274

136. 2,5-dihydroxybenzoic Acid, Matrix Substance For Maldi-ms, >99.0% (hplc)

137. 2,5-dihydroxybenzoic Acid, Matrix Substance For Maldi-ms, >=99.5% (hplc), Ultra Pure

2.4 Create Date
2004-09-16
3 Chemical and Physical Properties
Molecular Weight 154.12 g/mol
Molecular Formula C7H6O4
XLogP31.6
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Exact Mass154.02660867 g/mol
Monoisotopic Mass154.02660867 g/mol
Topological Polar Surface Area77.8 Ų
Heavy Atom Count11
Formal Charge0
Complexity157
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 Metabolism/Metabolites

5-hydroxylation is a known human metabolite of salicylic acid.

S73 | METXBIODB | Metabolite Reaction Database from BioTransformer | DOI:10.5281/zenodo.4056560


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09-Jul-2021
22-Nov-2023
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ABOUT THIS PAGE

Gentisic Acid Manufacturers

A Gentisic Acid manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Gentisic Acid, including repackagers and relabelers. The FDA regulates Gentisic Acid manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Gentisic Acid API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Gentisic Acid Suppliers

A Gentisic Acid supplier is an individual or a company that provides Gentisic Acid active pharmaceutical ingredient (API) or Gentisic Acid finished formulations upon request. The Gentisic Acid suppliers may include Gentisic Acid API manufacturers, exporters, distributors and traders.

click here to find a list of Gentisic Acid suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Gentisic Acid USDMF

A Gentisic Acid DMF (Drug Master File) is a document detailing the whole manufacturing process of Gentisic Acid active pharmaceutical ingredient (API) in detail. Different forms of Gentisic Acid DMFs exist exist since differing nations have different regulations, such as Gentisic Acid USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Gentisic Acid DMF submitted to regulatory agencies in the US is known as a USDMF. Gentisic Acid USDMF includes data on Gentisic Acid's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Gentisic Acid USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Gentisic Acid suppliers with USDMF on PharmaCompass.

Gentisic Acid GMP

Gentisic Acid Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Gentisic Acid GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Gentisic Acid GMP manufacturer or Gentisic Acid GMP API supplier for your needs.

Gentisic Acid CoA

A Gentisic Acid CoA (Certificate of Analysis) is a formal document that attests to Gentisic Acid's compliance with Gentisic Acid specifications and serves as a tool for batch-level quality control.

Gentisic Acid CoA mostly includes findings from lab analyses of a specific batch. For each Gentisic Acid CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Gentisic Acid may be tested according to a variety of international standards, such as European Pharmacopoeia (Gentisic Acid EP), Gentisic Acid JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Gentisic Acid USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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