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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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CEP/COS

CEP/COS Certifications

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JDMF

JDMFs Filed

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EU WC

EU WC

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KDMF

KDMF

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VMF

NDC API

API REF. PRICE (USD/KG)

$
$ 0

MARKET PLACE

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FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

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Europe

Europe

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Canada

Canada

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Australia

Australia

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South Africa

South Africa

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Listed Dossiers

Listed Dossiers

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

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EDQM

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USP

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JP

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Others

PATENTS & EXCLUSIVITIES

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Health Canada Patents

DIGITAL CONTENT

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Stock Recap #PipelineProspector

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Weekly News Recap #Phispers

GLOBAL SALES INFORMATION

US Medicaid

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Annual Reports

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0RELATED EXCIPIENT COMPANIES

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Chemistry

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Also known as: Gepirone hcl, Travivo, Gepirone hydrochloride [usan], 83928-66-9, Tgfk07ad, Bmy 13805-1
Molecular Formula
C19H30ClN5O2
Molecular Weight
395.9  g/mol
InChI Key
DGOCVISYYYQFEP-UHFFFAOYSA-N
FDA UNII
80C9L8EP6V

Gepirone
1 2D Structure

Gepirone

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
4,4-dimethyl-1-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]piperidine-2,6-dione;hydrochloride
2.1.2 InChI
InChI=1S/C19H29N5O2.ClH/c1-19(2)14-16(25)24(17(26)15-19)9-4-3-8-22-10-12-23(13-11-22)18-20-6-5-7-21-18;/h5-7H,3-4,8-15H2,1-2H3;1H
2.1.3 InChI Key
DGOCVISYYYQFEP-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC1(CC(=O)N(C(=O)C1)CCCCN2CCN(CC2)C3=NC=CC=N3)C.Cl
2.2 Other Identifiers
2.2.1 UNII
80C9L8EP6V
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 4,4-dimethyl-1-(4-(4-(2-pyrimidinyl)-1-piperazinyl)butyl)-2,6-piperidinedione

2. Bmy 13805

3. Bmy-13805

4. Gepirone

5. Gepirone Monohydrochloride

6. Mj 13805

7. Mj 13805-1

8. Mj-13805

2.3.2 Depositor-Supplied Synonyms

1. Gepirone Hcl

2. Travivo

3. Gepirone Hydrochloride [usan]

4. 83928-66-9

5. Tgfk07ad

6. Bmy 13805-1

7. 80c9l8ep6v

8. Chembl1204187

9. Variza

10. Ariza

11. Bmy-13805-1

12. Gepirone Er

13. 3,3-dimethyl-1-(4-(4-(2-pyrimidinyl)-1-piperazinyl)butyl)glutarimide Monohydrochloride

14. Gepirone Hydrochloride (usan)

15. 2,6-piperidinedione, 4,4-dimethyl-1-(4-(4-(2-pyrimidinyl)-1-piperazinyl)butyl)-, Monohydrochloride

16. Bmy-13805

17. Unii-80c9l8ep6v

18. Bmy 138951

19. Schembl318838

20. Dtxsid30232812

21. Org-33062

22. Gepirone Hydrochloride [mart.]

23. Gepirone Hydrochloride [who-dd]

24. Sb19633

25. Mj-13805

26. D04314

27. Q27269140

28. 2,6-piperidinedione, 4,4-dimethyl-1-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-, Hydrochloride (1:1)

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 395.9 g/mol
Molecular Formula C19H30ClN5O2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Exact Mass395.2088029 g/mol
Monoisotopic Mass395.2088029 g/mol
Topological Polar Surface Area69.6 Ų
Heavy Atom Count27
Formal Charge0
Complexity476
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anti-Anxiety Agents

Agents that alleviate ANXIETY, tension, and ANXIETY DISORDERS, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. ADRENERGIC BETA-ANTAGONISTS are commonly used in the symptomatic treatment of anxiety but are not included here. (See all compounds classified as Anti-Anxiety Agents.)


Antidepressive Agents

Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems. (See all compounds classified as Antidepressive Agents.)


Serotonin Receptor Agonists

Endogenous compounds and drugs that bind to and activate SEROTONIN RECEPTORS. Many serotonin receptor agonists are used as ANTIDEPRESSANTS; ANXIOLYTICS; and in the treatment of MIGRAINE DISORDERS. (See all compounds classified as Serotonin Receptor Agonists.)


API SUPPLIERS

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01

HRV Global Life Sciences

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothHRV Global Life Sciences - Market Expansion Leader in Pharmaceuticals.

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USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
HRV Global Life Sciences

02

Erregierre SpA

Italy

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Medlab Asia & Asia Health
Not Confirmed
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Erregierre SpA

Italy

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Medlab Asia & Asia Health
Not Confirmed
USDMF arrow-down CEP/COS JDMF EU-WC NDC arrow-down KDMF VMF Others AUDIT
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03

MSN Laboratories

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Medlab Asia & Asia Health
Not Confirmed
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Patents & EXCLUSIVITIES

Check the patents & exclusivity for this product

US Patents

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01

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Medlab Asia & Asia Health
Not Confirmed

FABRE KRAMER

U.S.A
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Medlab Asia & Asia Health
Not Confirmed

GEPIRONE HYDROCHLORIDE

US Patent Number : 7538116

Drug Substance Claim :

Drug Product Claim :

Application Number : 21164

Patent Use Code : U-3699

Delist Requested :

Patent Use Description :

Patent Expiration Date : 2025-09-02

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02

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Medlab Asia & Asia Health
Not Confirmed

FABRE KRAMER

U.S.A
arrow
Medlab Asia & Asia Health
Not Confirmed

GEPIRONE HYDROCHLORIDE

US Patent Number : 7538116

Drug Substance Claim :

Drug Product Claim :

Application Number : 21164

Patent Use Code : U-3699

Delist Requested :

Patent Use Description :

Patent Expiration Date : 2025-09-02

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03

arrow
Medlab Asia & Asia Health
Not Confirmed

FABRE KRAMER

U.S.A
arrow
Medlab Asia & Asia Health
Not Confirmed

GEPIRONE HYDROCHLORIDE

US Patent Number : 7538116

Drug Substance Claim :

Drug Product Claim :

Application Number : 21164

Patent Use Code : U-3699

Delist Requested :

Patent Use Description :

Patent Expiration Date : 2025-09-02

blank

04

arrow
Medlab Asia & Asia Health
Not Confirmed

FABRE KRAMER

U.S.A
arrow
Medlab Asia & Asia Health
Not Confirmed

GEPIRONE HYDROCHLORIDE

US Patent Number : 7538116

Drug Substance Claim :

Drug Product Claim :

Application Number : 21164

Patent Use Code : U-3699

Delist Requested :

Patent Use Description :

Patent Expiration Date : 2025-09-02

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Full Screen ViewFULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

US Exclusivities

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01

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Medlab Asia & Asia Health
Not Confirmed

FABRE KRAMER

U.S.A
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Medlab Asia & Asia Health
Not Confirmed

GEPIRONE HYDROCHLORIDE

Exclusivity Code : NCE

Exclusivity Expiration Date : 2028-09-22

Application Number : 21164

Product Number : 1

Exclusivity Details :

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02

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Medlab Asia & Asia Health
Not Confirmed

FABRE KRAMER

U.S.A
arrow
Medlab Asia & Asia Health
Not Confirmed

GEPIRONE HYDROCHLORIDE

Exclusivity Code : NCE

Exclusivity Expiration Date : 2028-09-22

Application Number : 21164

Product Number : 3

Exclusivity Details :

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03

arrow
Medlab Asia & Asia Health
Not Confirmed

FABRE KRAMER

U.S.A
arrow
Medlab Asia & Asia Health
Not Confirmed

GEPIRONE HYDROCHLORIDE

Exclusivity Code : NCE

Exclusivity Expiration Date : 2028-09-22

Application Number : 21164

Product Number : 2

Exclusivity Details :

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04

arrow
Medlab Asia & Asia Health
Not Confirmed

FABRE KRAMER

U.S.A
arrow
Medlab Asia & Asia Health
Not Confirmed

GEPIRONE HYDROCHLORIDE

Exclusivity Code : NCE

Exclusivity Expiration Date : 2028-09-22

Application Number : 21164

Product Number : 4

Exclusivity Details :

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