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Synopsis

ACTIVE PHARMA INGREDIENTS

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Chemistry

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Also known as: Gynosaponin c, 41753-43-9, Gypenoside iii, Sanchinoside e1, Arasaponin e1, Panax saponin e
Molecular Formula
C54H92O23
Molecular Weight
1109.3  g/mol
InChI Key
GZYPWOGIYAIIPV-JBDTYSNRSA-N
FDA UNII
7413S0WMH6

Ginsenoside Rb1
(2S,3R,4S,5S,6R)-2-{[(2S)-2-[(1S,3aR,3bR,5aR,7S,9aR,9bR,11R,11aR)-7-{[(2R,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxan-2-yl]oxy}-11-hydroxy-3a,3b,6,6,9a-pentamethyl-dodecahydro-1H-cyclopenta[a]phenanthren-1-yl]-6-methylhept-5-en-2-yl]oxy}-6-({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxane-3,4,5-triol is a natural product found in Panax vietnamensis, Gynostemma pentaphyllum, and other organisms with data available.
1 2D Structure

Ginsenoside Rb1

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2R,3R,4S,5S,6R)-2-[[(2R,3S,4S,5R,6S)-6-[(2S)-2-[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-3-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-12-hydroxy-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-methylhept-5-en-2-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
2.1.2 InChI
InChI=1S/C54H92O23/c1-23(2)10-9-14-54(8,77-48-44(69)40(65)37(62)29(74-48)22-70-46-42(67)38(63)34(59)26(19-55)71-46)24-11-16-53(7)33(24)25(58)18-31-51(5)15-13-32(50(3,4)30(51)12-17-52(31,53)6)75-49-45(41(66)36(61)28(21-57)73-49)76-47-43(68)39(64)35(60)27(20-56)72-47/h10,24-49,55-69H,9,11-22H2,1-8H3/t24-,25+,26+,27+,28+,29+,30-,31+,32-,33-,34+,35+,36+,37+,38-,39-,40-,41-,42+,43+,44+,45+,46+,47-,48-,49-,51-,52+,53+,54-/m0/s1
2.1.3 InChI Key
GZYPWOGIYAIIPV-JBDTYSNRSA-N
2.1.4 Canonical SMILES
CC(=CCCC(C)(C1CCC2(C1C(CC3C2(CCC4C3(CCC(C4(C)C)OC5C(C(C(C(O5)CO)O)O)OC6C(C(C(C(O6)CO)O)O)O)C)C)O)C)OC7C(C(C(C(O7)COC8C(C(C(C(O8)CO)O)O)O)O)O)O)C
2.1.5 Isomeric SMILES
CC(=CCC[C@@](C)([C@H]1CC[C@@]2([C@@H]1[C@@H](C[C@H]3[C@]2(CC[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O)C)C)O)C)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO[C@H]8[C@@H]([C@H]([C@@H]([C@H](O8)CO)O)O)O)O)O)O)C
2.2 Other Identifiers
2.2.1 UNII
7413S0WMH6
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 3-glcglc-20-glcglc-ginsenoside

2. Arasaponin E1

3. Ginsenoside-rb1

4. Gynosaponin C

5. Gypenoside Iii

6. Notoginsenoside Rb1

7. Panax Saponin E

8. Panaxoside Rb1

9. Pseudoginsenoside D

10. Sanchinoside E1

11. Sanchinoside Rb1

2.3.2 Depositor-Supplied Synonyms

1. Gynosaponin C

2. 41753-43-9

3. Gypenoside Iii

4. Sanchinoside E1

5. Arasaponin E1

6. Panax Saponin E

7. Pseudoginsenoside D

8. Ginsenoside-rb1

9. Panaxsaponin E

10. (20s)-ginsenoside Rb1

11. Chembl501515

12. Grb 1

13. Chebi:67989

14. Sanchinoside Rb1

15. 7413s0wmh6

16. Notoginsenoside Rb1

17. 2-o-beta-glucopyranosyl-(3beta,12beta)-20-[(6-o-beta-d-glucopyranosyl-beta-d-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl Beta-d-glucopyranoside

18. Ginsenosiderb1

19. Einecs 255-532-8

20. Mfcd00133367

21. Panaxoside Rb1

22. 2-o-beta-glucopyranosyl-(3beta,12beta)-20-((6-o-beta-d-glucopyranosyl-beta-d-glucopyranosyl)oxy)-12-hydroxydammar-24-en-3-yl-beta-d-glucopyranoside

23. Unii-7413s0wmh6

24. Gypenoside Cento

25. Nsc-310103

26. Nsc 310103

27. Gsrb1

28. Gs-rb1

29. 20(s)-ginsenoside Rb1

30. Ginsenoside Rb1 - 94%

31. Bidd:er0108

32. Ginsenoside Rb1 [usp-rs]

33. Ginsenoside Rb1 [who-dd]

34. Dtxsid401316929

35. Hms3885o12

36. Ex-a6786

37. Hy-n0039

38. Bdbm50317541

39. S3924

40. Akos025311537

41. Ccg-270640

42. Cs-3829

43. Db06749

44. Ncgc00347398-04

45. Bs-32417

46. Xg164977

47. N1620

48. C20713

49. 753g439

50. Q-100470

51. Ginsenoside Rb1, Primary Pharmaceutical Reference Standard

52. Ginsenoside Rb1, European Pharmacopoeia (ep) Reference Standard

53. Ginsenoside-rb1 From Panax Ginseng (korean Ginseng) Root, Triterpenoid Saponin

54. (3beta,12beta)-20-[(6-o-beta-d-glucopyranosyl-beta-d-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl 2-o-beta-d-glucopyranosyl-beta-d-glucopyranoside

55. (3beta,12beta)-20-{[6-o-(beta-d-glucopyranosyl)-beta-d-glucopyranosyl]oxy}-12-hydroxydammar-24-en-3-yl 2-o-beta-d-glucopyranosyl-beta-d-glucopyranoside

56. .beta.-d-glucopyranoside, (3.beta.,12.beta.)-20-((6-o-.beta.-d-glucopyranosyl-.beta.-d-glucopyranosyl)oxy)-12-hydroxydammar-24-en-3-yl 2-o-.beta.-d-glucopyranosyl-

57. 3beta-[beta-d-glucopyranosyl-(1->2)-beta-d Glucopyranosyloxy]-20-[beta-d-glucopyranosyl-(1->2)-beta-d Glucopyranosyloxy]dammar-24-en-12beta-ol

58. Beta-d-glucopyranoside, (3-beta,12-beta)-20-((6-o-beta-d-glucopyranosyl-beta-d-glucopyranosyl)oxy)-12-hydroxydammar-24-en-3-yl 2-o-beta-d-glucopyranosyl-

59. Ginsenoside Rb1 (constituent Of American Ginseng, Asian Ginseng, And Tienchi Ginseng) [dsc]

2.4 Create Date
2006-10-25
3 Chemical and Physical Properties
Molecular Weight 1109.3 g/mol
Molecular Formula C54H92O23
XLogP30.3
Hydrogen Bond Donor Count15
Hydrogen Bond Acceptor Count23
Rotatable Bond Count16
Exact Mass1108.60293918 g/mol
Monoisotopic Mass1108.60293918 g/mol
Topological Polar Surface Area377 Ų
Heavy Atom Count77
Formal Charge0
Complexity2000
Isotope Atom Count0
Defined Atom Stereocenter Count30
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

REF. STANDARDS & IMPURITIES

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Ginsenoside Rb1 Manufacturers

A Ginsenoside Rb1 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Ginsenoside Rb1, including repackagers and relabelers. The FDA regulates Ginsenoside Rb1 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Ginsenoside Rb1 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Ginsenoside Rb1 manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Ginsenoside Rb1 Suppliers

A Ginsenoside Rb1 supplier is an individual or a company that provides Ginsenoside Rb1 active pharmaceutical ingredient (API) or Ginsenoside Rb1 finished formulations upon request. The Ginsenoside Rb1 suppliers may include Ginsenoside Rb1 API manufacturers, exporters, distributors and traders.

click here to find a list of Ginsenoside Rb1 suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Ginsenoside Rb1 GMP

Ginsenoside Rb1 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Ginsenoside Rb1 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Ginsenoside Rb1 GMP manufacturer or Ginsenoside Rb1 GMP API supplier for your needs.

Ginsenoside Rb1 CoA

A Ginsenoside Rb1 CoA (Certificate of Analysis) is a formal document that attests to Ginsenoside Rb1's compliance with Ginsenoside Rb1 specifications and serves as a tool for batch-level quality control.

Ginsenoside Rb1 CoA mostly includes findings from lab analyses of a specific batch. For each Ginsenoside Rb1 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Ginsenoside Rb1 may be tested according to a variety of international standards, such as European Pharmacopoeia (Ginsenoside Rb1 EP), Ginsenoside Rb1 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Ginsenoside Rb1 USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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