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Synopsis

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Chemistry

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Also known as: 14197-60-5, 20s-ginsenoside rg3, (20s)-propanaxadiol, 20s-propanaxadiol, (20s)-ginsenoside rg3, S-ginsenoside rg3
Molecular Formula
C42H72O13
Molecular Weight
785.0  g/mol
InChI Key
RWXIFXNRCLMQCD-JBVRGBGGSA-N
FDA UNII
227D367Y57

Ginsenoside Rg3
ginsenoside rg3 is a natural product found in Panax ginseng, Panax notoginseng, and other organisms with data available.
1 2D Structure

Ginsenoside Rg3

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-2-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-17-[(2S)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
2.1.2 InChI
InChI=1S/C42H72O13/c1-21(2)10-9-14-42(8,51)22-11-16-41(7)29(22)23(45)18-27-39(5)15-13-28(38(3,4)26(39)12-17-40(27,41)6)54-37-35(33(49)31(47)25(20-44)53-37)55-36-34(50)32(48)30(46)24(19-43)52-36/h10,22-37,43-51H,9,11-20H2,1-8H3/t22-,23+,24+,25+,26-,27+,28-,29-,30+,31+,32-,33-,34+,35+,36-,37-,39-,40+,41+,42-/m0/s1
2.1.3 InChI Key
RWXIFXNRCLMQCD-JBVRGBGGSA-N
2.1.4 Canonical SMILES
CC(=CCCC(C)(C1CCC2(C1C(CC3C2(CCC4C3(CCC(C4(C)C)OC5C(C(C(C(O5)CO)O)O)OC6C(C(C(C(O6)CO)O)O)O)C)C)O)C)O)C
2.1.5 Isomeric SMILES
CC(=CCC[C@@](C)([C@H]1CC[C@@]2([C@@H]1[C@@H](C[C@H]3[C@]2(CC[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O)C)C)O)C)O)C
2.2 Other Identifiers
2.2.1 UNII
227D367Y57
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 20(r)-ginsenoside Rg(3)

2. 20(s)-ginsenoside Rg(3)

3. 20s-ginsenoside Rg3

4. 3-o-beta-d-glucopyranosyl-(1->2)-beta-d-glucopyranosyldammar-24-ene-3beta,12beta,20s-triol

5. Beta-d-glucopyranoside, (3beta,12beta)-12,20-dihydroxydammar-24-en-3-yl 2-o-beta-d-glucopyranosyl-

6. Ginsenoside 20-rg3

7. Ginsenoside Rg(3)

8. Ginsenoside Rg3, (+)-

9. Ginsenoside Rg3, (s)-

10. S-ginsenoside Rg3

2.3.2 Depositor-Supplied Synonyms

1. 14197-60-5

2. 20s-ginsenoside Rg3

3. (20s)-propanaxadiol

4. 20s-propanaxadiol

5. (20s)-ginsenoside Rg3

6. S-ginsenoside Rg3

7. 20(s)-ginsenoside Rg3

8. 20(s)-ginsenoside-rg3

9. 20(s)-propanaxidiol

10. Chembl398412

11. Chebi:67991

12. (2s,3r,4s,5s,6r)-2-[(2r,3r,4s,5s,6r)-4,5-dihydroxy-2-[[(3s,5r,8r,9r,10r,12r,13r,14r,17s)-12-hydroxy-17-[(2s)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1h-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol

13. 11019-45-7

14. 227d367y57

15. (r)ginsenoside-rg3

16. Ginsenoside 20-rg3

17. Ginsenoside Rg3, (s)-

18. Ginsenoside Rg3, (+)-

19. Unii-227d367y57

20. Rg3

21. Mfcd06410950

22. Ginsenoside Rg3,(s)

23. 2'(r)-ginsenoside-rg3

24. Gtpl7658

25. Ginsenoside Rg3 [who-dd]

26. Dtxsid101316982

27. Hms3886b14

28. Bdbm50317537

29. Ginsenoside Rg3, Analytical Standard

30. S9022

31. Zinc96085900

32. Ginsenoside Rg3, >=98% (hplc)

33. Akos037514674

34. Ccg-270472

35. (3beta,12beta)-12,20-dihydroxydammar-24-en-3-yl 2-o-beta-d-glucopyranosyl-beta-d-glucopyranoside

36. As-56617

37. Dammar-24-ene-12-beta,20-diol, 3-beta-((2-o-beta-d-glucopyranosyl-beta-d-glucopyransoyl)oxy)-

38. C20778

39. 197g605

40. Q-100154

41. Q27077807

42. .beta.-d-glucopyranoside, (3.beta.,12.beta.)-12,20-dihydroxydammar-24-en-3-yl 2-o-.beta.-d-glucopyranosyl-

43. 3-o-.beta.-d-glucopyranosyl-(1->2)-.beta.-d-glucopyranosyldammar-24-ene-3.beta.,12.beta.,20s-triol

44. Beta-d-glucopyranoside, (3-beta,12-beta)-12,20-dihydroxydammar-24-en-3-yl 2-o-beta-d-glucopyranosyl-

45. Dammar-24-ene-12beta,20-diol, 3-beta-((2-o-beta-d-glucopyranosyl-beta-d-glucopyransoyl)oxy)-

2.4 Create Date
2006-10-25
3 Chemical and Physical Properties
Molecular Weight 785.0 g/mol
Molecular Formula C42H72O13
XLogP34
Hydrogen Bond Donor Count9
Hydrogen Bond Acceptor Count13
Rotatable Bond Count10
Exact Mass784.49729235 g/mol
Monoisotopic Mass784.49729235 g/mol
Topological Polar Surface Area219 Ų
Heavy Atom Count55
Formal Charge0
Complexity1370
Isotope Atom Count0
Defined Atom Stereocenter Count20
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antineoplastic Agents, Phytogenic

Agents obtained from higher plants that have demonstrable cytostatic or antineoplastic activity. (See all compounds classified as Antineoplastic Agents, Phytogenic.)


ABOUT THIS PAGE

Ginsenoside Rg3 Manufacturers

A Ginsenoside Rg3 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Ginsenoside Rg3, including repackagers and relabelers. The FDA regulates Ginsenoside Rg3 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Ginsenoside Rg3 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Ginsenoside Rg3 manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Ginsenoside Rg3 Suppliers

A Ginsenoside Rg3 supplier is an individual or a company that provides Ginsenoside Rg3 active pharmaceutical ingredient (API) or Ginsenoside Rg3 finished formulations upon request. The Ginsenoside Rg3 suppliers may include Ginsenoside Rg3 API manufacturers, exporters, distributors and traders.

click here to find a list of Ginsenoside Rg3 suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Ginsenoside Rg3 NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Ginsenoside Rg3 as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Ginsenoside Rg3 API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Ginsenoside Rg3 as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Ginsenoside Rg3 and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Ginsenoside Rg3 NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Ginsenoside Rg3 suppliers with NDC on PharmaCompass.

Ginsenoside Rg3 GMP

Ginsenoside Rg3 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Ginsenoside Rg3 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Ginsenoside Rg3 GMP manufacturer or Ginsenoside Rg3 GMP API supplier for your needs.

Ginsenoside Rg3 CoA

A Ginsenoside Rg3 CoA (Certificate of Analysis) is a formal document that attests to Ginsenoside Rg3's compliance with Ginsenoside Rg3 specifications and serves as a tool for batch-level quality control.

Ginsenoside Rg3 CoA mostly includes findings from lab analyses of a specific batch. For each Ginsenoside Rg3 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Ginsenoside Rg3 may be tested according to a variety of international standards, such as European Pharmacopoeia (Ginsenoside Rg3 EP), Ginsenoside Rg3 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Ginsenoside Rg3 USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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