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Chemistry

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Also known as: 59870-68-7, 4-[(3r)-8,8-dimethyl-3,4-dihydro-2h-pyrano[2,3-f]chromen-3-yl]benzene-1,3-diol, 4-(3,4-dihydro-8,8-dimethyl-2h,8h-benzo(1,2-b:3,4-b')dipyran-3-yl)-1,3-benzenediol, Chebi:5369, Hoc5567t41, (r)-4-(8,8-dimethyl-2,3,4,8-tetrahydropyrano[2,3-f]chromen-3-yl)benzene-1,3-diol
Molecular Formula
C20H20O4
Molecular Weight
324.4  g/mol
InChI Key
LBQIJVLKGVZRIW-ZDUSSCGKSA-N
FDA UNII
HOC5567T41

Glabridin
glabridin is a natural product found in Ornithopus sativus, Glycyrrhiza glabra, and Glycyrrhiza uralensis with data available.
1 2D Structure

Glabridin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
4-[(3R)-8,8-dimethyl-3,4-dihydro-2H-pyrano[2,3-f]chromen-3-yl]benzene-1,3-diol
2.1.2 InChI
InChI=1S/C20H20O4/c1-20(2)8-7-16-18(24-20)6-3-12-9-13(11-23-19(12)16)15-5-4-14(21)10-17(15)22/h3-8,10,13,21-22H,9,11H2,1-2H3/t13-/m0/s1
2.1.3 InChI Key
LBQIJVLKGVZRIW-ZDUSSCGKSA-N
2.1.4 Canonical SMILES
CC1(C=CC2=C(O1)C=CC3=C2OCC(C3)C4=C(C=C(C=C4)O)O)C
2.1.5 Isomeric SMILES
CC1(C=CC2=C(O1)C=CC3=C2OC[C@H](C3)C4=C(C=C(C=C4)O)O)C
2.2 Other Identifiers
2.2.1 UNII
HOC5567T41
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 4-(3,4-dihydro-8,8-dimethyl-2h,8h-benzo(1,2-b:3,4-b')dipyran-3-yl)-1,3-benzenediol

2.3.2 Depositor-Supplied Synonyms

1. 59870-68-7

2. 4-[(3r)-8,8-dimethyl-3,4-dihydro-2h-pyrano[2,3-f]chromen-3-yl]benzene-1,3-diol

3. 4-(3,4-dihydro-8,8-dimethyl-2h,8h-benzo(1,2-b:3,4-b')dipyran-3-yl)-1,3-benzenediol

4. Chebi:5369

5. Hoc5567t41

6. (r)-4-(8,8-dimethyl-2,3,4,8-tetrahydropyrano[2,3-f]chromen-3-yl)benzene-1,3-diol

7. 1,3-benzenediol, 4-(3,4-dihydro-8,8-dimethyl-2h,8h-benzo(1,2-b:3,4-b')dipyran-3-yl)-, (r)-

8. Q-100692

9. (r)-glabridin

10. (r)-4-(8,8-dimethyl-3,4-dihydro-2h,8h-pyrano[2,3-f]chromen-3-yl)benzene-1,3-diol

11. 4-[(3r)-8,8-dimethyl-2h,3h,4h,8h-pyrano[2,3-f]chromen-3-yl]benzene-1,3-diol

12. 4-[(3r)-8,8-dimethyl-3,4-dihydro-2h,8h-pyrano[2,3-f]chromen-3-yl]benzene-1,3-diol

13. Glabioidin

14. Unii-hoc5567t41

15. 1,3-benzenediol, 4-((3r)-3,4-dihydro-8,8-dimethyl-2h,8h-benzo(1,2-b:3,4-b')dipyran-3-yl)-

16. 1,3-benzenediol, 4-[(3r)-3,4-dihydro-8,8-dimethyl-2h,8h-benzo[1,2-b:3,4-b']dipyran-3-yl]-

17. Mfcd03427694

18. Ls-176045

19. Glabridin [inci]

20. Glabridin [who-dd]

21. Mls000697609

22. Bidd:er0172

23. Glabridin, Analytical Standard

24. Schembl114869

25. Amy381

26. Chembl480477

27. Dtxsid00208589

28. Hms2271g14

29. Hms3885m04

30. Hy-n0393

31. Zinc4098719

32. Bdbm50441626

33. Lmpk12080012

34. S3786

35. Stl566095

36. Akos015903270

37. Glabridin, >=98% (hplc), Powder

38. Ccg-223443

39. 4-[(3r)-3,4-dihydro-8,8-dimethyl-2h,8h-benzo[1,2-b:3,4-b']dipyran-3-yl]-1,3-benzenediol

40. Ncgc00247524-01

41. Ac-31452

42. As-74264

43. Smr000470944

44. Kb-289522

45. Cs-0008929

46. N1579

47. 870g687

48. A913838

49. Q2386110

50. 4-[(3r)-8,8-dimethyl-3,4-dihydro-2h-pyrano[2,3-f]chromen- 3-yl]benzene-1,3-diol

51. 4-[(3r)-8,8-dimethyl-3,4-dihydro-2h-pyrano[6,5-f]chromen-3-yl]benzene-1,3-diol

52. 1,3-benzenediol,4-(3,4-dihydro-8,8-dimethyl-2h,8h-benzo(1,2-b:3,4-b')dipyran-3-yl)-,(r); 4-(3,4-dihydro-8,8-dimethyl-2h,8h-benzo(1,2-b:3,4-b')dipyran-3-yl)-1,3-benzenediol

53. 1,3-benzenediol,4-(3,4-dihydro-8,8-dimethyl-2h,8h-benzo[1,2-b:3,4-b']dipyran-3-yl)-,(r)-

54. 4-((r)-8,8-dimethyl-3,4-dihydro-2h,8h-benzo[1,2-b:4,3-b']dipyran-3-yl)-benzene-1,3-diol

55. 4-[(3r)-8,8-dimethyl-3,4-dihydro-2h,8h-benzo[1,2-b:3,4-b']dipyran-3-yl]benzene-1,3-diol

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 324.4 g/mol
Molecular Formula C20H20O4
XLogP33.9
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Exact Mass324.13615911 g/mol
Monoisotopic Mass324.13615911 g/mol
Topological Polar Surface Area58.9 Ų
Heavy Atom Count24
Formal Charge0
Complexity488
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

API Reference Price

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09-Jan-2021
22-Oct-2024
KGS
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Average Price (USD/KGS)

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Total Quantity (KGS)

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Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

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ABOUT THIS PAGE

Glabridin Manufacturers

A Glabridin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Glabridin, including repackagers and relabelers. The FDA regulates Glabridin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Glabridin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Glabridin manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Glabridin Suppliers

A Glabridin supplier is an individual or a company that provides Glabridin active pharmaceutical ingredient (API) or Glabridin finished formulations upon request. The Glabridin suppliers may include Glabridin API manufacturers, exporters, distributors and traders.

click here to find a list of Glabridin suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Glabridin GMP

Glabridin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Glabridin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Glabridin GMP manufacturer or Glabridin GMP API supplier for your needs.

Glabridin CoA

A Glabridin CoA (Certificate of Analysis) is a formal document that attests to Glabridin's compliance with Glabridin specifications and serves as a tool for batch-level quality control.

Glabridin CoA mostly includes findings from lab analyses of a specific batch. For each Glabridin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Glabridin may be tested according to a variety of international standards, such as European Pharmacopoeia (Glabridin EP), Glabridin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Glabridin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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