Find GLPG1205 manufacturers, exporters & distributors on PharmaCompass

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Chemistry

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Also known as: Glpg1205, Glpg-1205, 1445847-37-9, K9wr6lra5d, 9-(2-cyclopropylethynyl)-2-[[(2s)-1,4-dioxan-2-yl]methoxy]-6,7-dihydropyrimido[6,1-a]isoquinolin-4-one, (s)-2-((1,4-dioxan-2-yl)methoxy)-9-(cyclopropylethynyl)-6,7-dihydro-4h-pyrimido[6,1-a]isoquinolin-4-one
Molecular Formula
C22H22N2O4
Molecular Weight
378.4  g/mol
InChI Key
IRBAWVGZNJIROV-SFHVURJKSA-N
FDA UNII
K9WR6LRA5D

GLPG1205
GLPG-1205 is under investigation in clinical trial NCT03725852 (A Clinical Study to Test How Effective and Safe GLPG1205 is for Patients With Idiopathic Pulmonary Fibrosis (IPF)).
1 2D Structure

GLPG1205

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
9-(2-cyclopropylethynyl)-2-[[(2S)-1,4-dioxan-2-yl]methoxy]-6,7-dihydropyrimido[6,1-a]isoquinolin-4-one
2.1.2 InChI
InChI=1S/C22H22N2O4/c25-22-23-21(28-14-18-13-26-9-10-27-18)12-20-19-6-5-16(4-3-15-1-2-15)11-17(19)7-8-24(20)22/h5-6,11-12,15,18H,1-2,7-10,13-14H2/t18-/m0/s1
2.1.3 InChI Key
IRBAWVGZNJIROV-SFHVURJKSA-N
2.1.4 Canonical SMILES
C1CC1C#CC2=CC3=C(C=C2)C4=CC(=NC(=O)N4CC3)OCC5COCCO5
2.1.5 Isomeric SMILES
C1CC1C#CC2=CC3=C(C=C2)C4=CC(=NC(=O)N4CC3)OC[C@@H]5COCCO5
2.2 Other Identifiers
2.2.1 UNII
K9WR6LRA5D
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 9-cyclopropylethynyl-2-((s)-1-(1,4)dioxan-2-ylmethoxy)-6,7-dihydropyrimido(6,1-a)isoquinolin-4-one

2. Glpg1205

2.3.2 Depositor-Supplied Synonyms

1. Glpg1205

2. Glpg-1205

3. 1445847-37-9

4. K9wr6lra5d

5. 9-(2-cyclopropylethynyl)-2-[[(2s)-1,4-dioxan-2-yl]methoxy]-6,7-dihydropyrimido[6,1-a]isoquinolin-4-one

6. (s)-2-((1,4-dioxan-2-yl)methoxy)-9-(cyclopropylethynyl)-6,7-dihydro-4h-pyrimido[6,1-a]isoquinolin-4-one

7. Unii-k9wr6lra5d

8. Chembl3716365

9. Schembl15051377

10. Gtpl10171

11. Bdbm50548385

12. At30151

13. Db15346

14. Compound 122 [wo2013092791a1]

15. Hy-135303

16. Cs-0110898

2.4 Create Date
2013-07-29
3 Chemical and Physical Properties
Molecular Weight 378.4 g/mol
Molecular Formula C22H22N2O4
XLogP32.4
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Exact Mass378.15795719 g/mol
Monoisotopic Mass378.15795719 g/mol
Topological Polar Surface Area60.4 Ų
Heavy Atom Count28
Formal Charge0
Complexity757
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

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ABOUT THIS PAGE

Looking for 1445847-37-9 / GLPG1205 API manufacturers, exporters & distributors?

GLPG1205 manufacturers, exporters & distributors 1

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PharmaCompass offers a list of GLPG1205 API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right GLPG1205 manufacturer or GLPG1205 supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred GLPG1205 manufacturer or GLPG1205 supplier.

PharmaCompass also assists you with knowing the GLPG1205 API Price utilized in the formulation of products. GLPG1205 API Price is not always fixed or binding as the GLPG1205 Price is obtained through a variety of data sources. The GLPG1205 Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

GLPG1205

Synonyms

Glpg-1205, 1445847-37-9, K9wr6lra5d, 9-(2-cyclopropylethynyl)-2-[[(2s)-1,4-dioxan-2-yl]methoxy]-6,7-dihydropyrimido[6,1-a]isoquinolin-4-one, (s)-2-((1,4-dioxan-2-yl)methoxy)-9-(cyclopropylethynyl)-6,7-dihydro-4h-pyrimido[6,1-a]isoquinolin-4-one, Unii-k9wr6lra5d

Cas Number

1445847-37-9

Unique Ingredient Identifier (UNII)

K9WR6LRA5D

About GLPG1205

GLPG-1205 is under investigation in clinical trial NCT03725852 (A Clinical Study to Test How Effective and Safe GLPG1205 is for Patients With Idiopathic Pulmonary Fibrosis (IPF)).

GLPG1205 Manufacturers

A GLPG1205 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of GLPG1205, including repackagers and relabelers. The FDA regulates GLPG1205 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. GLPG1205 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

GLPG1205 Suppliers

A GLPG1205 supplier is an individual or a company that provides GLPG1205 active pharmaceutical ingredient (API) or GLPG1205 finished formulations upon request. The GLPG1205 suppliers may include GLPG1205 API manufacturers, exporters, distributors and traders.

GLPG1205 GMP

GLPG1205 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of GLPG1205 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right GLPG1205 GMP manufacturer or GLPG1205 GMP API supplier for your needs.

GLPG1205 CoA

A GLPG1205 CoA (Certificate of Analysis) is a formal document that attests to GLPG1205's compliance with GLPG1205 specifications and serves as a tool for batch-level quality control.

GLPG1205 CoA mostly includes findings from lab analyses of a specific batch. For each GLPG1205 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

GLPG1205 may be tested according to a variety of international standards, such as European Pharmacopoeia (GLPG1205 EP), GLPG1205 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (GLPG1205 USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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