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Chemistry

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Also known as: Glucomannoglycan, 76081-94-2, (glucomannan)n, (glucomannan)n+1, Chebi:17020, C01810
Molecular Formula
C24H42O21
Molecular Weight
666.6  g/mol
InChI Key
LUEWUZLMQUOBSB-FSKGGBMCSA-N

Glucomannan
(2R,3S,4R,6R)-5-{[(2S,3S,4R,5S,6R)-5-{[(2S,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-{[(2S,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxan-2-yl]oxy}-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-6-(hydroxymethyl)oxane-2,3,4-triol is a natural product found in Aloe vera, Phoenix dactylifera, and Phoenix theophrasti with data available.
1 2D Structure

Glucomannan

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2S,3S,4S,5S,6R)-2-[(2R,3S,4R,5R,6S)-6-[(2R,3S,4R,5S,6S)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2R,4R,5S,6R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
2.1.2 InChI
InChI=1S/C24H42O21/c25-1-5-9(29)10(30)15(35)22(40-5)44-19-7(3-27)42-24(17(37)12(19)32)45-20-8(4-28)41-23(16(36)13(20)33)43-18-6(2-26)39-21(38)14(34)11(18)31/h5-38H,1-4H2/t5-,6-,7-,8-,9-,10+,11-,12-,13-,14+,15+,16+,17-,18?,19-,20-,21-,22+,23+,24+/m1/s1
2.1.3 InChI Key
LUEWUZLMQUOBSB-FSKGGBMCSA-N
2.1.4 Canonical SMILES
C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)OC4C(OC(C(C4O)O)O)CO)CO)CO)O)O)O)O
2.1.5 Isomeric SMILES
C([C@@H]1[C@H]([C@@H]([C@@H]([C@@H](O1)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2O)O)O[C@@H]3[C@H](O[C@H]([C@H]([C@H]3O)O)OC4[C@H](O[C@H]([C@H]([C@H]4O)O)O)CO)CO)CO)O)O)O)O
2.2 Synonyms
2.2.1 MeSH Synonyms

1. (1-6)-alpha-d-gluco-d-mannan

2. (1-6)-alpha-glucomannan

3. Glucomanna

4. Konjac Gluco-mannan

5. Konjac Glucomannan

6. Konjac Mannan

2.2.2 Depositor-Supplied Synonyms

1. Glucomannoglycan

2. 76081-94-2

3. (glucomannan)n

4. (glucomannan)n+1

5. Chebi:17020

6. C01810

2.3 Create Date
2008-09-10
3 Chemical and Physical Properties
Molecular Weight 666.6 g/mol
Molecular Formula C24H42O21
XLogP3-9
Hydrogen Bond Donor Count14
Hydrogen Bond Acceptor Count21
Rotatable Bond Count10
Exact Mass666.22185834 g/mol
Monoisotopic Mass666.22185834 g/mol
Topological Polar Surface Area348 Ų
Heavy Atom Count45
Formal Charge0
Complexity918
Isotope Atom Count0
Defined Atom Stereocenter Count19
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Cathartics

Agents that are used to stimulate evacuation of the bowels. (See all compounds classified as Cathartics.)


ABOUT THIS PAGE

Glucomannan Manufacturers

A Glucomannan manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Glucomannan, including repackagers and relabelers. The FDA regulates Glucomannan manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Glucomannan API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Glucomannan Suppliers

A Glucomannan supplier is an individual or a company that provides Glucomannan active pharmaceutical ingredient (API) or Glucomannan finished formulations upon request. The Glucomannan suppliers may include Glucomannan API manufacturers, exporters, distributors and traders.

Glucomannan GMP

Glucomannan Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Glucomannan GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Glucomannan GMP manufacturer or Glucomannan GMP API supplier for your needs.

Glucomannan CoA

A Glucomannan CoA (Certificate of Analysis) is a formal document that attests to Glucomannan's compliance with Glucomannan specifications and serves as a tool for batch-level quality control.

Glucomannan CoA mostly includes findings from lab analyses of a specific batch. For each Glucomannan CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Glucomannan may be tested according to a variety of international standards, such as European Pharmacopoeia (Glucomannan EP), Glucomannan JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Glucomannan USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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