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Chemistry

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Also known as: 475-31-0, Glycocholate, Cholylglycine, N-choloylglycine, Glycine, n-choloyl-, Glycocholic acid hydrate
Molecular Formula
C26H43NO6
Molecular Weight
465.6  g/mol
InChI Key
RFDAIACWWDREDC-FRVQLJSFSA-N
FDA UNII
G59NX3I3RT

Glycocholic Acid
The glycine conjugate of CHOLIC ACID. It acts as a detergent to solubilize fats for absorption and is itself absorbed.
1 2D Structure

Glycocholic Acid

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-[[(4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]acetic acid
2.1.2 InChI
InChI=1S/C26H43NO6/c1-14(4-7-22(31)27-13-23(32)33)17-5-6-18-24-19(12-21(30)26(17,18)3)25(2)9-8-16(28)10-15(25)11-20(24)29/h14-21,24,28-30H,4-13H2,1-3H3,(H,27,31)(H,32,33)/t14-,15+,16-,17-,18+,19+,20-,21+,24+,25+,26-/m1/s1
2.1.3 InChI Key
RFDAIACWWDREDC-FRVQLJSFSA-N
2.1.4 Canonical SMILES
CC(CCC(=O)NCC(=O)O)C1CCC2C1(C(CC3C2C(CC4C3(CCC(C4)O)C)O)O)C
2.1.5 Isomeric SMILES
C[C@H](CCC(=O)NCC(=O)O)[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)O)C
2.2 Other Identifiers
2.2.1 UNII
G59NX3I3RT
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Cholylglycine

2. Glycine Cholate

3. Glycocholate

4. Glycocholate Sodium

5. Glycocholic Acid, Sodium Salt

2.3.2 Depositor-Supplied Synonyms

1. 475-31-0

2. Glycocholate

3. Cholylglycine

4. N-choloylglycine

5. Glycine, N-choloyl-

6. Glycocholic Acid Hydrate

7. Glycine, N-[(3a,5b,7a,12a)-3,7,12-trihydroxy-24-oxocholan-24-yl]-

8. N-cholylglycine

9. G59nx3i3rt

10. Chembl411070

11. Chebi:17687

12. 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-oylglycine

13. N-(3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-oyl)glycine

14. N-(3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-oyl)-glycine

15. Glycine, N-((3alpha,5beta,7alpha,12alpha)-3,7,12-trihydroxy-24-oxocholan-24-yl)-

16. 2-[[(4r)-4-[(3r,5s,7r,8r,9s,10s,12s,13r,14s,17r)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]acetic Acid

17. N-((3alpha,5beta,7alpha,12alpha)-3,7,12-trihydroxy-24-oxocholan-24-yl)glycine

18. N-[(3alpha,5beta,7alpha,12alpha)-3,7,12-trihydroxy-24-oxocholan-24-yl]glycine

19. 2-[(4r)-4-[(1s,2s,5r,7s,9r,10r,11s,14r,15r,16s)-5,9,16-trihydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-14-yl]pentanamido]acetic Acid

20. Gch

21. Unii-g59nx3i3rt

22. Glycylcholate

23. Mfcd00065902

24. Glycylcholic Acid

25. N-choloyl-glycine

26. Cas-475-31-0

27. Prestwick_768

28. Einecs 207-494-9

29. Prestwick0_000521

30. Prestwick1_000521

31. Prestwick2_000521

32. Prestwick3_000521

33. Spectrum5_002011

34. Bmse000651

35. Glycocholic Acid, Free Acid

36. Dsstox_cid_27436

37. Dsstox_rid_82346

38. Bidd:pxr0160

39. Dsstox_gsid_47436

40. Glycoreductodehydrocholic Acid

41. Schembl29022

42. Bspbio_000501

43. Mls002153857

44. Glycocholic Acid [mi]

45. Spbio_002422

46. Bpbio1_000553

47. Gtpl4544

48. Dtxsid2047436

49. 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-oic Acid N-(carboxymethyl)amide

50. Glycine, N-[(3alpha,5beta,7alpha,12alpha)-3,7,12-trihydroxy-24-oxocholan-24-yl]-

51. Glycocholic Acid [who-dd]

52. Hms1569j03

53. Hms2096j03

54. Hms2231a05

55. N-(3-alpha,7-alpha,12-alpha-trihydroxycholan-24-oyl)glycine

56. Hy-n1423

57. N-(carboxymethyl)-3alpha,7alpha,12alpha-trihydroxyglycine Cholate

58. Zinc8143774

59. Tox21_302549

60. Bdbm50375589

61. Lmst05030001

62. S4958

63. Stl565148

64. Akos015965042

65. Ccg-269413

66. Cs-w020037

67. Ds-0968

68. Ncgc00163115-02

69. Ncgc00256646-01

70. Ac-30905

71. Smr001233215

72. 3a,7a,12a-trihydroxy-5b-cholan-24-oylglycine

73. C01921

74. G-5270

75. 475g310

76. A827264

77. 3a,7a,12a-trihydroxy-5b-cholanic Acid-24-glycine

78. Q2701638

79. Brd-k54771420-001-03-2

80. [(3,7,12-trihydroxy-24-oxocholan-24-yl)amino]acetic Acid #

81. 3a,7a,12a-trihydroxy-n-(carboxymethyl)-5b-cholan-24-amide

82. N-(carboxymethyl)-3a,7a,12a-trihydroxy-5b-cholan-24-amide

83. 5beta-cholanic Acid-3alpha,7alpha,12alpha-triol N-(carboxymethyl)-amide

84. N-[(3alpha,5beta,7alpha,8xi,12alpha)-3,7,12-trihydroxy-24-oxocholan-24-yl]glycine

85. N-[(3beta,5beta,7beta,9beta,12beta)-3,7,12-trihydroxy-24-oxocholan-24-yl]glycine

86. ((r)-4-((3r,5s,7r,8r,9s,10s,12s,13r,14s,17r)-3,7,12-trihydroxy-10,13-dimethylhexadecahydro-1h-cyclopenta[a]phenanthren-17-yl)pentanoyl)glycine;glycocholic Acid

87. 2-[(4r)-4-[(1s,2s,5r,7s,9r,10r,11s,14r,15r,16s)-5,9,16-trihydroxy-2,15-dimethyltetracyclo[8.7.0.0?,?.0??,??]heptadecan-14-yl]pentanamido]acetic Acid

2.4 Create Date
2005-06-01
3 Chemical and Physical Properties
Molecular Weight 465.6 g/mol
Molecular Formula C26H43NO6
XLogP32.9
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Exact Mass465.30903809 g/mol
Monoisotopic Mass465.30903809 g/mol
Topological Polar Surface Area127 Ų
Heavy Atom Count33
Formal Charge0
Complexity759
Isotope Atom Count0
Defined Atom Stereocenter Count11
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Detergents

Purifying or cleansing agents, usually salts of long-chain aliphatic bases or acids, that exert cleansing (oil-dissolving) and antimicrobial effects through a surface action that depends on possessing both hydrophilic and hydrophobic properties. (See all compounds classified as Detergents.)


Cholagogues and Choleretics

Gastrointestinal agents that stimulate the flow of bile into the duodenum (cholagogues) or stimulate the production of bile by the liver (choleretic). (See all compounds classified as Cholagogues and Choleretics.)


Listed Suppliers

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01

Dipharma

Italy
BIO Partnering at JPM
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Dipharma

Italy
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BIO Partnering at JPM
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Glycocholic Acid

About the Company : Dipharma is a leading European manufacturer of Active Pharmaceutical Ingredients that has been developing innovative and proprietary processes since 1949. We support our custome...

Dipharma is a leading European manufacturer of Active Pharmaceutical Ingredients that has been developing innovative and proprietary processes since 1949. We support our customers worldwide with a strong and well resourced R&D team, three cGMP facilities in Europe, and offer world-renowned expertise in handling hazardous chemical processes. Our customers can benefit from our broad portfolio of generic Active Pharmaceutical Ingredients and a wide range of advanced technologies available for custom synthesis. They can rely on the highest quality standards, but it does not stop there, they can count on our experience in innovation.
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02

BIO Partnering at JPM
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BIO Partnering at JPM
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Glycocholic Acid

About the Company : Sichuan Renan Pharmaceutical Co., Ltd., founded in June 2013 with 325 acres and more than 1000 employees , located in Yuechi Pharmaceutical Industrial Park, Guangan city Sichuan pr...

Sichuan Renan Pharmaceutical Co., Ltd., founded in June 2013 with 325 acres and more than 1000 employees , located in Yuechi Pharmaceutical Industrial Park, Guangan city Sichuan province,China , is a wholly-owned subsidiary of Chengdu Brilliant Pharmaceutical Co., Ltd group. Renan Pharma is PMDA and EU approved , it is a high-tech innovative enterprise committed to the research & development, producing and sales of high-tech APIs and intermediates for global.
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10-Jun-2021
18-Jun-2024
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ABOUT THIS PAGE

Glycocholic Acid Manufacturers

A Glycocholic Acid manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Glycocholic Acid, including repackagers and relabelers. The FDA regulates Glycocholic Acid manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Glycocholic Acid API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Glycocholic Acid manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Glycocholic Acid Suppliers

A Glycocholic Acid supplier is an individual or a company that provides Glycocholic Acid active pharmaceutical ingredient (API) or Glycocholic Acid finished formulations upon request. The Glycocholic Acid suppliers may include Glycocholic Acid API manufacturers, exporters, distributors and traders.

click here to find a list of Glycocholic Acid suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Glycocholic Acid GMP

Glycocholic Acid Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Glycocholic Acid GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Glycocholic Acid GMP manufacturer or Glycocholic Acid GMP API supplier for your needs.

Glycocholic Acid CoA

A Glycocholic Acid CoA (Certificate of Analysis) is a formal document that attests to Glycocholic Acid's compliance with Glycocholic Acid specifications and serves as a tool for batch-level quality control.

Glycocholic Acid CoA mostly includes findings from lab analyses of a specific batch. For each Glycocholic Acid CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Glycocholic Acid may be tested according to a variety of international standards, such as European Pharmacopoeia (Glycocholic Acid EP), Glycocholic Acid JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Glycocholic Acid USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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