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Chemistry

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Also known as: 489-84-9, 1,4-dimethyl-7-isopropylazulene, Vetivazulen, 7-isopropyl-1,4-dimethylazulene, Azulon, Kessazulen
Molecular Formula
C15H18
Molecular Weight
198.30  g/mol
InChI Key
FWKQNCXZGNBPFD-UHFFFAOYSA-N
FDA UNII
2OZ1K9JKQC

Guaiazulene
azulon is a natural product found in Mikania cordifolia, Santolina corsica, and other organisms with data available.
1 2D Structure

Guaiazulene

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
1,4-dimethyl-7-propan-2-ylazulene
2.1.2 InChI
InChI=1S/C15H18/c1-10(2)13-7-5-11(3)14-8-6-12(4)15(14)9-13/h5-10H,1-4H3
2.1.3 InChI Key
FWKQNCXZGNBPFD-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC1=C2C=CC(=C2C=C(C=C1)C(C)C)C
2.2 Other Identifiers
2.2.1 UNII
2OZ1K9JKQC
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Azulon

2. Guajazulene

2.3.2 Depositor-Supplied Synonyms

1. 489-84-9

2. 1,4-dimethyl-7-isopropylazulene

3. Vetivazulen

4. 7-isopropyl-1,4-dimethylazulene

5. Azulon

6. Kessazulen

7. Purazulen

8. Silazulon

9. Uroazulen

10. Azunol

11. S-guaiazulene

12. Eucazulen

13. Guajazulene

14. Guiazulene

15. Cuteazul

16. Gurjunazulen

17. Azulen-beris

18. Guaiazulen

19. 3,8-dimethyl-5-(2-propyl)azulene

20. Azulene, 1,4-dimethyl-7-(1-methylethyl)-

21. Vaumigan

22. 1,4-dimethyl-7-propan-2-ylazulene

23. 1,4-dimethyl-7-(1-methylethyl)azulene

24. Azulol

25. 1,4-dimethyl-7-(propan-2-yl)azulene

26. Eucazulene

27. Hepatoprotectant

28. Nsc 4714

29. Azulene, 7-isopropyl-1,4-dimethyl-

30. Az-8 Beris

31. Azunol (tn)

32. 7-isopropyl-1,4-dimethyl-azulene

33. Azulene, 1,4-dimethyl-7-isopropyl-

34. Nsc-4714

35. 2oz1k9jkqc

36. 1,3,5,7,9-guaiapentaene

37. Chebi:5550

38. 1,4-dimethyl-7-isopropyl-azulene

39. 1,4-dimethyl-7-isopropylazulene (jan)

40. Ncgc00095836-02

41. Dsstox_cid_25996

42. Dsstox_rid_81279

43. Dsstox_gsid_45996

44. Cas-489-84-9

45. 1,4-dimethyl-7-isopropylazulene [jan]

46. 7-isopropyl- 1,4-dimethylazulene

47. Einecs 207-701-2

48. Unii-2oz1k9jkqc

49. Brn 1365001

50. Guajazulen

51. Kessazulene

52. S-kessazulene

53. Guaiazulene, 99%

54. Mfcd00003811

55. Azulene,4-dimethyl-

56. Spectrum_001198

57. Guaiazulene [mi]

58. Spectrum2_001089

59. Spectrum3_001537

60. Spectrum4_000762

61. Spectrum5_001090

62. Guaiazulene [inci]

63. Guaiazulene [mart.]

64. Bspbio_002954

65. Guaiazulene [who-dd]

66. Kbiogr_001144

67. Kbioss_001678

68. 4-05-00-01751 (beilstein Handbook Reference)

69. Mls002207286

70. Divk1c_001006

71. Spectrum1502249

72. Spbio_001138

73. Az-8

74. 1,4-dimethyl-7-isopropylazulen

75. Chembl1408759

76. Dtxsid7045996

77. Hms503i13

78. Kbio1_001006

79. Kbio2_001678

80. Kbio2_004246

81. Kbio2_006814

82. Kbio3_002454

83. Azulene,4-dimethyl-7-isopropyl-

84. Nsc4714

85. Ninds_001006

86. 1, 4-dimethyl-7-isopropylazulene

87. Zinc968478

88. Hy-n6951

89. Tox21_111526

90. Bbl027440

91. Ccg-40099

92. S3995

93. Stk801958

94. Akos001082716

95. Tox21_111526_1

96. Db13329

97. Lmpr0103410006

98. Sdccgmls-0066686.p001

99. Wln: L57j B1 F1 Iy1&1

100. Idi1_001006

101. Azulene,4-dimethyl-7-(1-methylethyl)-

102. Ncgc00095836-01

103. Ncgc00095836-03

104. Ncgc00095836-05

105. Ncgc00178373-01

106. 1,4-dimethyl-7-(1-methylethyl)-azulene

107. As-13972

108. Smr001306801

109. Db-051592

110. Azulene, 7-isopropyl-1,4-dimethyl- (8ci)

111. Cs-0021588

112. Ft-0626818

113. G0228

114. 7-isopropyl-1,4-dimethyl-azulene;guaiazulene

115. 1,4-dimethyl-7-(1-methyl)-azulene (azulon)

116. 1,4-dimethyl-7-(1-methylethyl)azulene, 9ci

117. C09675

118. D01037

119. A827639

120. Sr-05000002441

121. Guaiazulene (constituent Of Chamomile) [dsc]

122. Q3026266

123. Sr-05000002441-1

124. Brd-k36719159-001-04-9

125. Z56347227

2.4 Create Date
2005-03-25
3 Chemical and Physical Properties
Molecular Weight 198.30 g/mol
Molecular Formula C15H18
XLogP34.8
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count0
Rotatable Bond Count1
Exact Mass198.140850574 g/mol
Monoisotopic Mass198.140850574 g/mol
Topological Polar Surface Area0 Ų
Heavy Atom Count15
Formal Charge0
Complexity206
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 ATC Code

S - Sensory organs

S01 - Ophthalmologicals

S01X - Other ophthalmologicals

S01XA - Other ophthalmologicals

S01XA01 - Guaiazulen


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ABOUT THIS PAGE

Guaiazulene Manufacturers

A Guaiazulene manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Guaiazulene, including repackagers and relabelers. The FDA regulates Guaiazulene manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Guaiazulene API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Guaiazulene Suppliers

A Guaiazulene supplier is an individual or a company that provides Guaiazulene active pharmaceutical ingredient (API) or Guaiazulene finished formulations upon request. The Guaiazulene suppliers may include Guaiazulene API manufacturers, exporters, distributors and traders.

click here to find a list of Guaiazulene suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Guaiazulene WC

A Guaiazulene written confirmation (Guaiazulene WC) is an official document issued by a regulatory agency to a Guaiazulene manufacturer, verifying that the manufacturing facility of a Guaiazulene active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Guaiazulene APIs or Guaiazulene finished pharmaceutical products to another nation, regulatory agencies frequently require a Guaiazulene WC (written confirmation) as part of the regulatory process.

click here to find a list of Guaiazulene suppliers with Written Confirmation (WC) on PharmaCompass.

Guaiazulene GMP

Guaiazulene Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Guaiazulene GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Guaiazulene GMP manufacturer or Guaiazulene GMP API supplier for your needs.

Guaiazulene CoA

A Guaiazulene CoA (Certificate of Analysis) is a formal document that attests to Guaiazulene's compliance with Guaiazulene specifications and serves as a tool for batch-level quality control.

Guaiazulene CoA mostly includes findings from lab analyses of a specific batch. For each Guaiazulene CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Guaiazulene may be tested according to a variety of international standards, such as European Pharmacopoeia (Guaiazulene EP), Guaiazulene JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Guaiazulene USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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