Synopsis
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South Africa
DRUG PRODUCT COMPOSITIONS
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1. Bs 100 141
2. Bs-100-141
3. Bs100141
4. Estulic
5. Guanfacine
6. Guanfacine Monohydrochloride
7. Hydrochloride, Guanfacine
8. Lon798
9. Monohydrochloride, Guanfacine
10. Tenex
1. 29110-48-3
2. Guanfacine Hcl
3. Tenex
4. Intuniv
5. Guanfacine (hydrochloride)
6. N-carbamimidoyl-2-(2,6-dichlorophenyl)acetamide Hydrochloride
7. Estulic
8. Bs 100-141
9. 29520-14-7
10. N-(aminoiminomethyl)-2,6-dichlorobenzeneacetamide Hydrochloride
11. Spd503
12. N-amidino-2-(2,6-dichlorophenyl)acetamide Hydrochloride
13. N-amidino-2-(2,6-dichlorophenyl)acetamide Monohydrochloride
14. Guafacine Hydrochloride
15. Bs-100-141
16. Benzeneacetamide, N-(aminoiminomethyl)-2,6-dichloro-, Monohydrochloride
17. Spd 503
18. Mls000069745
19. Pml56a160o
20. Smr000058453
21. 29110-48-3 (hcl)
22. Dsstox_cid_25157
23. Dsstox_rid_80708
24. Dsstox_gsid_45157
25. Connexyn
26. Lon 798
27. N-(diaminomethylidene)-2-(2,6-dichlorophenyl)acetamide;hydrochloride
28. Cas-29520-14-7
29. Guanfacinehcl
30. Tenex (tn)
31. Guanfacinehydrochloride
32. Sr-01000075893
33. Ncgc00015469-05
34. Einecs 249-443-3
35. N-(aminoiminomethyl)-2,6-dichlorophenylacetamide Monohydrochloride
36. Unii-pml56a160o
37. Spd-503
38. Prestwick_740
39. Guanfacine Hydrochloride (jan/usp)
40. Intuniv (tn)
41. Mfcd00798230
42. Guanfacine Hydrochloride [usan:usp:jan]
43. Opera_id_1928
44. N-(diaminomethylidene)-2-(2,6-dichlorophenyl)acetamide Hydrochloride
45. Benzeneacetamide, N-(aminoiminomethyl)-2,6-dichloro-, Hydrochloride (1:1)
46. G 1043
47. Schembl41681
48. Mls001077329
49. Mls002222252
50. [(2,6-dichlorophenyl)acetyl]guanidine Hydrochloride
51. Chebi:5559
52. Chembl1200494
53. Dtxsid2045157
54. Schembl15603414
55. Hms1569c19
56. Hms3747e15
57. Pharmakon1600-01505435
58. Bcp21710
59. N-(aminoiminomethyl)-2,6-dichloro-benzeneacetamide Hydrochloride
60. Tox21_110159
61. Tox21_500519
62. Guanfacine Hydrochloride [mi]
63. Nsc759121
64. S4693
65. Guanfacine Hydrochloride [jan]
66. Akos015966858
67. Akos030242245
68. Tox21_110159_1
69. Ccg-213439
70. Ccg-220339
71. Cs-1254
72. Guanfacine Hydrochloride [usan]
73. Lp00519
74. Guanfacine Hydrochloride [mart.]
75. Guanfacine Hydrochloride [vandf]
76. Guanfacine Hydrochloride [usp-rs]
77. Guanfacine Hydrochloride [who-dd]
78. Ncgc00015469-09
79. Ncgc00093914-01
80. Ncgc00093914-02
81. Ncgc00180965-01
82. Ncgc00261204-01
83. As-12253
84. Hy-17416
85. Guanfacine Hydrochloride, >=98% (hplc)
86. Bs100-141
87. Db-047525
88. Eu-0100519
89. Ft-0630546
90. Ft-0698181
91. G0414
92. Guanfacine Hydrochloride [orange Book]
93. D00606
94. Guanfacine Hydrochloride [usp Monograph]
95. T72238
96. A826918
97. J-017395
98. S-877503
99. Sr-01000075893-1
100. Sr-01000075893-3
101. Sr-01000075893-6
102. Q27286641
103. N-carbamimidoyl-2-(2,6-dichlorophenyl)-acetamide Hydrochloride
104. Guanfacine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material
105. Guanfacine Hydrochloride, United States Pharmacopeia (usp) Reference Standard
106. N-[bis(azanyl)methylidene]-2-[2,6-bis(chloranyl)phenyl]ethanamide Hydrochloride
Molecular Weight | 282.5 g/mol |
---|---|
Molecular Formula | C9H10Cl3N3O |
Hydrogen Bond Donor Count | 3 |
Hydrogen Bond Acceptor Count | 1 |
Rotatable Bond Count | 2 |
Exact Mass | 280.988945 g/mol |
Monoisotopic Mass | 280.988945 g/mol |
Topological Polar Surface Area | 81.5 Ų |
Heavy Atom Count | 16 |
Formal Charge | 0 |
Complexity | 256 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently Bonded Unit Count | 2 |
1 of 4 | |
---|---|
Drug Name | Guanfacine hydrochloride |
Drug Label | Tenex (guanfacine hydrochloride) is a centrally acting antihypertensive with 2-adrenoceptor agonist properties in tablet form for oral administration. The chemical name of Tenex (guanfacine hydrochloride) is N-amidino- 2-(2,6-dichlorophenyl) acetam... |
Active Ingredient | Guanfacine hydrochloride |
Dosage Form | Tablet, extended release; Tablet |
Route | oral; Oral |
Strength | eq 4mg base; eq 2mg base; 1mg; eq 1mg base; eq 3mg base; 4mg; 2mg; 3mg |
Market Status | Tentative Approval; Prescription |
Company | Twi Pharms; Epic Pharma; Teva Pharms Usa; Sandoz; Watson Labs; Actavis Elizabeth; Amneal Pharm; Mylan |
2 of 4 | |
---|---|
Drug Name | Tenex |
PubMed Health | Guanfacine (By mouth) |
Drug Classes | Antihypertensive, Cardiovascular Agent, Central Nervous System Agent |
Drug Label | Tenex (guanfacine hydrochloride) is a centrally acting antihypertensive with 2-adrenoceptor agonist properties in tablet form for oral administration. The chemical name of Tenex (guanfacine hydrochloride) is N-amidino- 2-(2,6-dichlorophenyl) acetam... |
Active Ingredient | Guanfacine hydrochloride |
Dosage Form | Tablet |
Route | Oral |
Strength | eq 2mg base; eq 1mg base |
Market Status | Prescription |
Company | Promius Pharma |
3 of 4 | |
---|---|
Drug Name | Guanfacine hydrochloride |
Drug Label | Tenex (guanfacine hydrochloride) is a centrally acting antihypertensive with 2-adrenoceptor agonist properties in tablet form for oral administration. The chemical name of Tenex (guanfacine hydrochloride) is N-amidino- 2-(2,6-dichlorophenyl) acetam... |
Active Ingredient | Guanfacine hydrochloride |
Dosage Form | Tablet, extended release; Tablet |
Route | oral; Oral |
Strength | eq 4mg base; eq 2mg base; 1mg; eq 1mg base; eq 3mg base; 4mg; 2mg; 3mg |
Market Status | Tentative Approval; Prescription |
Company | Twi Pharms; Epic Pharma; Teva Pharms Usa; Sandoz; Watson Labs; Actavis Elizabeth; Amneal Pharm; Mylan |
4 of 4 | |
---|---|
Drug Name | Tenex |
PubMed Health | Guanfacine (By mouth) |
Drug Classes | Antihypertensive, Cardiovascular Agent, Central Nervous System Agent |
Drug Label | Tenex (guanfacine hydrochloride) is a centrally acting antihypertensive with 2-adrenoceptor agonist properties in tablet form for oral administration. The chemical name of Tenex (guanfacine hydrochloride) is N-amidino- 2-(2,6-dichlorophenyl) acetam... |
Active Ingredient | Guanfacine hydrochloride |
Dosage Form | Tablet |
Route | Oral |
Strength | eq 2mg base; eq 1mg base |
Market Status | Prescription |
Company | Promius Pharma |
Intuniv is indicated for the treatment of attention deficit hyperactivity disorder (ADHD) in children and adolescents 6 17 years old for whom stimulants are not suitable, not tolerated or have been shown to be ineffective.
Intuniv must be used as a part of a comprehensive ADHD treatment programme, typically including psychological, educational and social measures.
Adrenergic alpha-2 Receptor Agonists
Compounds that bind to and activate ADRENERGIC ALPHA-2 RECEPTORS. (See all compounds classified as Adrenergic alpha-2 Receptor Agonists.)
Antihypertensive Agents
Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS. (See all compounds classified as Antihypertensive Agents.)
C02AC02
Medichem is a vertically integrated pharmaceutical company specializing in the development & manufacturing of APIs & FDFs.
GDUFA
DMF Review : Complete
Rev. Date : 2013-02-26
Pay. Date : 2013-02-05
DMF Number : 8590
Submission : 1990-06-12
Status : Active
Type : II
GDUFA
DMF Review : Complete
Rev. Date : 2016-11-18
Pay. Date : 2016-08-23
DMF Number : 28049
Submission : 2014-03-07
Status : Active
Type : II
GDUFA
DMF Review : N/A
Rev. Date :
Pay. Date :
DMF Number : 36431
Submission : 2021-12-23
Status : Active
Type : II
GDUFA
DMF Review : Complete
Rev. Date : 2015-02-24
Pay. Date : 2014-06-19
DMF Number : 28312
Submission : 2014-05-19
Status : Active
Type : II
GDUFA
DMF Review : Complete
Rev. Date : 2014-08-01
Pay. Date : 2014-07-29
DMF Number : 8661
Submission : 1990-07-12
Status : Active
Type : II
GDUFA
DMF Review : N/A
Rev. Date :
Pay. Date :
DMF Number : 4985
Submission : 1983-04-22
Status : Inactive
Type : II
GDUFA
DMF Review : N/A
Rev. Date :
Pay. Date :
DMF Number : 4784
Submission : 1982-12-06
Status : Inactive
Type : II
GDUFA
DMF Review : Complete
Rev. Date : 2014-10-27
Pay. Date : 2014-07-15
DMF Number : 28443
Submission : 2014-08-04
Status : Active
Type : II
GDUFA
DMF Review : Complete
Rev. Date : 2020-10-14
Pay. Date : 2020-09-08
DMF Number : 34653
Submission : 2020-03-26
Status : Active
Type : II
GDUFA
DMF Review : N/A
Rev. Date :
Pay. Date :
DMF Number : 39404
Submission : 2024-01-11
Status : Active
Type : II
Medichem is a vertically integrated pharmaceutical company specializing in the development & manufacturing of APIs & FDFs.
About the Company : Medichem is an indepently-owned company based in Barcelona. Founded in 1972 and with more than 45 years, Medichem has been engaged in the process development and manufacture of Act...
About the Company : More than 35 years of dedication to quality, service and pursuit of excellence, CHEMO was founded by Hugo Sigman, M.D., and Silvia Gold, Biochemist, in Spain (Barcelona), in 1977, ...
About the Company : Guangzhou Tosun Pharmaceutical was founded in 1999, which mainly focuses on importation & exportation of Active Pharmaceutical Ingrediants, Chemical Raw Materials, Intermediate, Ex...
About the Company : Harman Finochem Limited is a leading India-based Pharmaceutical Company which specializes in the manufacture and export of more than 45 Active Pharmaceutical Ingredients (APls) of ...
About the Company : Jubilant Life Sciences Limited, is an integrated global pharmaceutical and life sciences company engaged in manufacture and supply of APIs, Solid Dosage Formulations, Radiopharmace...
About the Company : Procos S.p.A. is a wholly owned subsidiary of the Japanese company, CBC Co. Ltd Group, specializing in the development, scale-up and production of Active Pharmaceutical Ingredients...
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