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Chemistry

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Also known as: H3b-6545, 2052130-80-8, (e)-n,n-dimethyl-4-((2-((5-((z)-4,4,4-trifluoro-1-(3-fluoro-1h-indazol-5-yl)-2-phenylbut-1-en-1-yl)pyridin-2-yl)oxy)ethyl)amino)but-2-enamide, Schembl18261010, Schembl22718548, Ex-a2942
Molecular Formula
C30H29F4N5O2
Molecular Weight
567.6  g/mol
InChI Key
JPFTZIJTXCHJNE-HMOQVRKWSA-N

H3B-6545
1 2D Structure

H3B-6545

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(E)-N,N-dimethyl-4-[2-[5-[(Z)-4,4,4-trifluoro-1-(3-fluoro-2H-indazol-5-yl)-2-phenylbut-1-enyl]pyridin-2-yl]oxyethylamino]but-2-enamide
2.1.2 InChI
InChI=1S/C30H29F4N5O2/c1-39(2)27(40)9-6-14-35-15-16-41-26-13-11-22(19-36-26)28(21-10-12-25-23(17-21)29(31)38-37-25)24(18-30(32,33)34)20-7-4-3-5-8-20/h3-13,17,19,35H,14-16,18H2,1-2H3,(H,37,38)/b9-6+,28-24-
2.1.3 InChI Key
JPFTZIJTXCHJNE-HMOQVRKWSA-N
2.1.4 Canonical SMILES
CN(C)C(=O)C=CCNCCOC1=NC=C(C=C1)C(=C(CC(F)(F)F)C2=CC=CC=C2)C3=CC4=C(NN=C4C=C3)F
2.1.5 Isomeric SMILES
CN(C)C(=O)/C=C/CNCCOC1=NC=C(C=C1)/C(=C(/CC(F)(F)F)\C2=CC=CC=C2)/C3=CC4=C(NN=C4C=C3)F
2.2 Synonyms
2.2.1 MeSH Synonyms

1. ((2e)-n,n-dimethyl-4-((2-((5-((1z)-4,4,4-trifluoro-1-(3-fluoro-1h-indazol-5-yl)-2-phenylbut-1-en-1-yl)pyridin-2-yl)oxy)ethyl)amino)but-2-enamide) Hydrochloride Salt

2. H3b-6545

2.2.2 Depositor-Supplied Synonyms

1. H3b-6545

2. 2052130-80-8

3. (e)-n,n-dimethyl-4-((2-((5-((z)-4,4,4-trifluoro-1-(3-fluoro-1h-indazol-5-yl)-2-phenylbut-1-en-1-yl)pyridin-2-yl)oxy)ethyl)amino)but-2-enamide

4. Schembl18261010

5. Schembl22718548

6. Ex-a2942

7. Cid 124091040

8. Hy-112596

9. Cs-0047714

10. (2e)-n,n-dimethyl-4-{[2-({5-[(1z)-4,4,4-trifluoro-1-(3-fluoro-1h-indazol-5-yl)-2-phenylbut-1-en-1-yl]pyridin-2-yl}oxy)ethyl]amino}but-2-enamide

2.3 Create Date
2017-02-18
3 Chemical and Physical Properties
Molecular Weight 567.6 g/mol
Molecular Formula C30H29F4N5O2
XLogP36.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count9
Rotatable Bond Count11
Exact Mass567.22573783 g/mol
Monoisotopic Mass567.22573783 g/mol
Topological Polar Surface Area83.1 Ų
Heavy Atom Count41
Formal Charge0
Complexity906
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count2
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

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Looking for / H3B-6545 API manufacturers, exporters & distributors?

H3B-6545 manufacturers, exporters & distributors 1

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PharmaCompass offers a list of H3B-6545 API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right H3B-6545 manufacturer or H3B-6545 supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred H3B-6545 manufacturer or H3B-6545 supplier.

PharmaCompass also assists you with knowing the H3B-6545 API Price utilized in the formulation of products. H3B-6545 API Price is not always fixed or binding as the H3B-6545 Price is obtained through a variety of data sources. The H3B-6545 Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

H3B-6545

Synonyms

2052130-80-8, (e)-n,n-dimethyl-4-((2-((5-((z)-4,4,4-trifluoro-1-(3-fluoro-1h-indazol-5-yl)-2-phenylbut-1-en-1-yl)pyridin-2-yl)oxy)ethyl)amino)but-2-enamide, Schembl18261010, Schembl22718548, Ex-a2942, Cid 124091040

H3B-6545 Manufacturers

A H3B-6545 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of H3B-6545, including repackagers and relabelers. The FDA regulates H3B-6545 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. H3B-6545 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

H3B-6545 Suppliers

A H3B-6545 supplier is an individual or a company that provides H3B-6545 active pharmaceutical ingredient (API) or H3B-6545 finished formulations upon request. The H3B-6545 suppliers may include H3B-6545 API manufacturers, exporters, distributors and traders.

H3B-6545 GMP

H3B-6545 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of H3B-6545 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right H3B-6545 GMP manufacturer or H3B-6545 GMP API supplier for your needs.

H3B-6545 CoA

A H3B-6545 CoA (Certificate of Analysis) is a formal document that attests to H3B-6545's compliance with H3B-6545 specifications and serves as a tool for batch-level quality control.

H3B-6545 CoA mostly includes findings from lab analyses of a specific batch. For each H3B-6545 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

H3B-6545 may be tested according to a variety of international standards, such as European Pharmacopoeia (H3B-6545 EP), H3B-6545 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (H3B-6545 USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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