Find Hemicholinium-3 manufacturers, exporters & distributors on PharmaCompass

PharmaCompass

Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

0

API Suppliers

API Suppliers

0

USDMF

US DMFs Filed

0

CEP/COS

CEP/COS Certifications

0

JDMF

JDMFs Filed

0

EU WC

EU WC

0

KDMF

KDMF

0

NDC API

NDC API

0

VMF

NDC API

0

Listed Suppliers

Other Suppliers

0INTERMEDIATES

REF. STANDARDS OR IMPURITIES

0

EDQM

0

USP

0

JP

0

Others

FINISHED DOSAGE FORMULATIONS

0

FDF Dossiers

FDF Dossiers

0

FDA Orange Book

FDA (Orange Book)

0

Europe

Europe

0

Canada

Canada

0

Australia

Australia

0

South Africa

South Africa

0

Listed Dossiers

Listed Dossiers

0 DRUGS IN DEVELOPMENT

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

PATENTS & EXCLUSIVITIES

0

US Patents

0

US Exclusivities

0

Health Canada Patents

API REF. PRICE (USD/KG)

$
$ 0

GLOBAL SALES INFORMATION

US Medicaid

NA

Annual Reports

NA

Regulatory FDF Prices

NA

API/FDF Prices: Book a Demo to
explore the features and consider
upgrading later

MARKET PLACE

0

API

0

FDF

DIGITAL CONTENT

0

Data Compilation #PharmaFlow

0

Stock Recap #PipelineProspector

0

Weekly News Recap #Phispers

0

News #PharmaBuzz

Chemistry

Click the arrow to open the dropdown
read-moreClick the button for full data set
Also known as: 312-45-8, Hemicholinium 3, Hemicholinium bromide, Hemicholine, Hemicholinium dibromide, Hemicholinium-3 bromide
Molecular Formula
C24H34Br2N2O4
Molecular Weight
574.3  g/mol
InChI Key
OPYKHUMNFAMIBL-UHFFFAOYSA-L
FDA UNII
65NY3I7ZD0

Hemicholinium-3
A potent inhibitor of the high affinity uptake system for CHOLINE. It has less effect on the low affinity uptake system. Since choline is one of the components of ACETYLCHOLINE, treatment with hemicholinium can deplete acetylcholine from cholinergic terminals. Hemicholinium 3 is commonly used as a research tool in animal and in vitro experiments.
1 2D Structure

Hemicholinium-3

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-[4-[4-(2-hydroxy-4,4-dimethylmorpholin-4-ium-2-yl)phenyl]phenyl]-4,4-dimethylmorpholin-4-ium-2-ol;dibromide
2.1.2 InChI
InChI=1S/C24H34N2O4.2BrH/c1-25(2)13-15-29-23(27,17-25)21-9-5-19(6-10-21)20-7-11-22(12-8-20)24(28)18-26(3,4)14-16-30-24;;/h5-12,27-28H,13-18H2,1-4H3;2*1H/q+2;;/p-2
2.1.3 InChI Key
OPYKHUMNFAMIBL-UHFFFAOYSA-L
2.1.4 Canonical SMILES
C[N+]1(CCOC(C1)(C2=CC=C(C=C2)C3=CC=C(C=C3)C4(C[N+](CCO4)(C)C)O)O)C.[Br-].[Br-]
2.2 Other Identifiers
2.2.1 UNII
65NY3I7ZD0
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Hemicholinium

2. Hemicholinium 3

2.3.2 Depositor-Supplied Synonyms

1. 312-45-8

2. Hemicholinium 3

3. Hemicholinium Bromide

4. Hemicholine

5. Hemicholinium Dibromide

6. Hemicholinium-3 Bromide

7. Hc-3

8. Hemicholinium 3 Dibromide

9. Hemicholinium-3 Dibromide

10. 65ny3i7zd0

11. Morpholinium, 2,2'-(1,1'-biphenyl)-4,4'-diylbis(2-hydroxy-4,4-dimethyl-, Dibromide

12. Morpholinium, 2,2'-(1,1'-biphenyl)-4,4'-diylbis(2-hydroxy-4,4-dimethyl-, Bromide (1:2)

13. Morpholinium, 2,2'-[1,1'-biphenyl]-4,4'-diylbis[2-hydroxy-4,4-dimethyl-, Dibromide

14. Hemicholinium 3 Dibromide; Hemicholinium Bromide; Hemicholinium Dibromide; Hemicholinium-3 Bromide

15. [3h]hemicholinium-3

16. Nsc-527583

17. [3h]-hemicholinium-3

18. Sr-01000075620

19. Einecs 206-227-3

20. Nsc 527583

21. Unii-65ny3i7zd0

22. [3h]hc-3

23. Prestwick_566

24. [3h]-hc-3

25. Hemicholiniumdibromide

26. Schembl564623

27. Chembl197027

28. Gtpl4493

29. Dtxsid80883358

30. Hms1569o07

31. Hms2096o07

32. Hms3261d18

33. Hms3713o07

34. Hms3885f21

35. Hy-b2152

36. Hemicholinium Dibromide [mi]

37. Tox21_500578

38. 2,2'-(4,4'-biphenylene)bis(2-hydroxy-4,4-dimethylmorpholinium Bromide)

39. 2,2'-(4,4'-biphenylene)bis(2-hydroxy-4,4-dimethylmorpholinium) Dibromide

40. Akos026750387

41. Ccg-220393

42. Ccg-221882

43. Lp00578

44. 2,2'-(1,1'-biphenyl)-4,4'-diylbis(2-hydroxy-4,4-dimethyl-morpholinium) Dibromide

45. Morpholinium, 2,2'-(1,1'-biphenyl)-4,4'-diylbis(2-hydroxy-4,4-dimethyl)-, Dibromide

46. Morpholinium, 2,2'-(4,4'-biphenylylene)bis(2-hydroxy-4,4-dimethyl-, Dibromide

47. Ncgc00093959-01

48. Ncgc00261263-01

49. Hemicholinium-3, Solid, >=95% (hplc)

50. Cs-0020304

51. Eu-0100578

52. Ft-0741707

53. H-108

54. J-018290

55. Sr-01000075620-1

56. Sr-01000075620-5

57. Q15409437

58. 2,2'-(biphenyl-4,4'-diyl)bis(2-hydroxy-4,4-dimethylmorpholin-4-ium) Bromide

59. 2-[4-[4-(2-hydroxy-4,4-dimethylmorpholin-4-ium-2-yl)phenyl]phenyl]-4,4-dimethylmorpholin-4-ium-2-ol;dibromide

60. 2-hydroxy-2-{4-[4-(2-hydroxy-4,4-dimethylmorpholin-4-ium-2-yl)phenyl]phenyl}-4,4-dimethylmorpholin-4-ium Dibromide

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 574.3 g/mol
Molecular Formula C24H34Br2N2O4
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count3
Exact Mass g/mol
Monoisotopic Mass g/mol
Topological Polar Surface Area58.9
Heavy Atom Count32
Formal Charge0
Complexity544
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count2
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count3
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Cholinergic Agents

Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of ACETYLCHOLINE, and drugs that affect the survival of cholinergic neurons. The term cholinergic agents is sometimes still used in the narrower sense of MUSCARINIC AGONISTS, although most modern texts discourage that usage. (See all compounds classified as Cholinergic Agents.)


Neurotransmitter Uptake Inhibitors

Drugs that inhibit the transport of neurotransmitters into axon terminals or into storage vesicles within terminals. For many transmitters, uptake determines the time course of transmitter action so inhibiting uptake prolongs the activity of the transmitter. Blocking uptake may also deplete available transmitter stores. Many clinically important drugs are uptake inhibitors although the indirect reactions of the brain rather than the acute block of uptake itself is often responsible for the therapeutic effects. (See all compounds classified as Neurotransmitter Uptake Inhibitors.)


ABOUT THIS PAGE

Looking for 312-45-8 / Hemicholinium-3 API manufacturers, exporters & distributors?

Hemicholinium-3 manufacturers, exporters & distributors 1

98

PharmaCompass offers a list of Hemicholinium-3 API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Hemicholinium-3 manufacturer or Hemicholinium-3 supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Hemicholinium-3 manufacturer or Hemicholinium-3 supplier.

PharmaCompass also assists you with knowing the Hemicholinium-3 API Price utilized in the formulation of products. Hemicholinium-3 API Price is not always fixed or binding as the Hemicholinium-3 Price is obtained through a variety of data sources. The Hemicholinium-3 Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Hemicholinium-3

Synonyms

312-45-8, Hemicholinium 3, Hemicholinium bromide, Hemicholine, Hemicholinium dibromide, Hemicholinium-3 bromide

Cas Number

312-45-8

Unique Ingredient Identifier (UNII)

65NY3I7ZD0

About Hemicholinium-3

A potent inhibitor of the high affinity uptake system for CHOLINE. It has less effect on the low affinity uptake system. Since choline is one of the components of ACETYLCHOLINE, treatment with hemicholinium can deplete acetylcholine from cholinergic terminals. Hemicholinium 3 is commonly used as a research tool in animal and in vitro experiments.

HEMICHOLINIUM 3 Manufacturers

A HEMICHOLINIUM 3 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of HEMICHOLINIUM 3, including repackagers and relabelers. The FDA regulates HEMICHOLINIUM 3 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. HEMICHOLINIUM 3 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

HEMICHOLINIUM 3 Suppliers

A HEMICHOLINIUM 3 supplier is an individual or a company that provides HEMICHOLINIUM 3 active pharmaceutical ingredient (API) or HEMICHOLINIUM 3 finished formulations upon request. The HEMICHOLINIUM 3 suppliers may include HEMICHOLINIUM 3 API manufacturers, exporters, distributors and traders.

HEMICHOLINIUM 3 GMP

HEMICHOLINIUM 3 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of HEMICHOLINIUM 3 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right HEMICHOLINIUM 3 GMP manufacturer or HEMICHOLINIUM 3 GMP API supplier for your needs.

HEMICHOLINIUM 3 CoA

A HEMICHOLINIUM 3 CoA (Certificate of Analysis) is a formal document that attests to HEMICHOLINIUM 3's compliance with HEMICHOLINIUM 3 specifications and serves as a tool for batch-level quality control.

HEMICHOLINIUM 3 CoA mostly includes findings from lab analyses of a specific batch. For each HEMICHOLINIUM 3 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

HEMICHOLINIUM 3 may be tested according to a variety of international standards, such as European Pharmacopoeia (HEMICHOLINIUM 3 EP), HEMICHOLINIUM 3 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (HEMICHOLINIUM 3 USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
Ask Us for Pharmaceutical Supplier and Partner
Ask Us, Find A Supplier / Partner
No Commissions, No Strings Attached, Get Connected for FREE

What are you looking for?

How can we help you?

The request can't be empty

Please read our Privacy Policy carefully

You must agree to the privacy policy

The name can't be empty
The company can't be empty.
The email can't be empty Please enter a valid email.
The mobile can't be empty