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1. 2615-15-8
2. 3,6,9,12,15-pentaoxaheptadecane-1,17-diol
3. Hexagol
4. Hexaoxyethylene Glycol
5. Ho-peg6-oh
6. Peg-6
7. Polyethylene Glycol 300
8. 2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanol
9. Polyoxyethylene (6)
10. Hexaethyleneglycol
11. Nsc 201209
12. Ethanol, 2,2'-(oxybis(ethyleneoxyethyleneoxy))di-
13. Chebi:49793
14. Mfcd00002877
15. Einecs 220-045-1
16. P6g
17. Oh-peg6-oh
18. Brn 1638281
19. Ai3-01457
20. Hexa[ethylene Glycol]
21. Hexaethylene Glycol, 97%
22. 2,2'-[oxybis(ethyleneoxyethyleneoxy)]bisethanol
23. Schembl38159
24. 4-01-00-02406 (beilstein Handbook Reference)
25. Chembl1235082
26. Dtxsid2058629
27. Wln: Q2/o2/ 5q
28. Amy19025
29. Zinc4521548
30. Nsc201209
31. Akos015839803
32. Nsc-201209
33. Ncgc00159371-02
34. Ncgc00159371-03
35. As-19157
36. Bp-21034
37. Bp-21475
38. Sy024148
39. Trans-2-o-tolylcyclopropanecarboxylic Acid
40. Hy-141230
41. 3,9,12,15-pentaoxaheptadecane-1,17-diol
42. Cs-0115001
43. Ft-0602028
44. H1432
45. Hexaethylene Glycol, Purum, >=95.0% (gc)
46. Ethanol,2'-[oxybis(ethyleneoxyethyleneoxy)]di-
47. A877353
48. J-016283
49. Q27104720
50. Ethanol,2'-[oxybis(oxy-2,1-ethanediyloxy-2,1-ethanediyloxy)]bis-
51. Ethanol, 2,2'-(oxybis(oxy-2,1-ethanediyloxy-2,1-ethanediyloxy))bis-
52. 2-[2-(2-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethanol
53. 6529-43-7
| Molecular Weight | 282.33 g/mol |
|---|---|
| Molecular Formula | C12H26O7 |
| XLogP3 | -1.9 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 16 |
| Exact Mass | 282.16785316 g/mol |
| Monoisotopic Mass | 282.16785316 g/mol |
| Topological Polar Surface Area | 86.6 Ų |
| Heavy Atom Count | 19 |
| Formal Charge | 0 |
| Complexity | 141 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
Indicated as a lubricant in over-the-counter ophthalmic solutions to temporarily relieve redness, burning and irritation of the eyes.
PEGs act as nonionic surfactant to decrease surface tension and condition the stratum corneum, thus enhance the diffusion of other molecules or drugs through the skin.
Absorption
PEGs can be absorbed by the gastrointestinal tract following oral administration with the fraction absorbed being dependent on the molecular weight of the compound. It is likely to display minimal absorption through the intact skin, but may penetrate through injured skin with compromised barrier function.
Route of Elimination
After oral and intravenous exposure, PEGs are excreted mainly unchanged in the urine and faeces.
Volume of Distribution
No pharmacokinetic data available.
Clearance
No pharmacokinetic data available.
Proportion of absorbed PEGs may be metabolized to lower oligomers, glycolic acid, hydroxyglycolic acids and the diglycolic acids homologs, carbon dioxide that is exhaled, and to a minor extent, oxalic acid.
No pharmacokinetic data available.
Due to their physical properties, PEG acts as a surfactant by coating the eye. It provides lubrication and surface protection in dry eyes.
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A Hexaethylene Glycol manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Hexaethylene Glycol, including repackagers and relabelers. The FDA regulates Hexaethylene Glycol manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Hexaethylene Glycol API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
A Hexaethylene Glycol supplier is an individual or a company that provides Hexaethylene Glycol active pharmaceutical ingredient (API) or Hexaethylene Glycol finished formulations upon request. The Hexaethylene Glycol suppliers may include Hexaethylene Glycol API manufacturers, exporters, distributors and traders.
Hexaethylene Glycol Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Hexaethylene Glycol GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Hexaethylene Glycol GMP manufacturer or Hexaethylene Glycol GMP API supplier for your needs.
A Hexaethylene Glycol CoA (Certificate of Analysis) is a formal document that attests to Hexaethylene Glycol's compliance with Hexaethylene Glycol specifications and serves as a tool for batch-level quality control.
Hexaethylene Glycol CoA mostly includes findings from lab analyses of a specific batch. For each Hexaethylene Glycol CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Hexaethylene Glycol may be tested according to a variety of international standards, such as European Pharmacopoeia (Hexaethylene Glycol EP), Hexaethylene Glycol JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Hexaethylene Glycol USP).
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