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1. Ncgc00167966-01
2. Dsstox_cid_26750
3. Dsstox_rid_81875
4. Dsstox_gsid_46750
5. Chembl1874250
6. Dtxsid20858848
7. Tox21_112595
8. Akos015960603
9. Ac-11740
10. Ac-31947
11. Cas-9004-61-9
12. (4xi)-alpha-d-xylo-hexopyranuronosyl-(1->3)-(3xi)-2-(acetylamino)-2-deoxy-beta-d-ribo-hexopyranosyl-(1->4)-(5xi)-beta-d-xylo-hexopyranuronosyl-(1->3)-2-(acetylamino)-2-deoxy-d-glucopyranose
1. Hyaluronan
Molecular Weight | 776.6 g/mol |
---|---|
Molecular Formula | C28H44N2O23 |
XLogP3 | -7.4 |
Hydrogen Bond Donor Count | 14 |
Hydrogen Bond Acceptor Count | 23 |
Rotatable Bond Count | 12 |
Exact Mass | 776.23348565 g/mol |
Monoisotopic Mass | 776.23348565 g/mol |
Topological Polar Surface Area | 400 Ų |
Heavy Atom Count | 53 |
Formal Charge | 0 |
Complexity | 1300 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 16 |
Undefined Atom Stereocenter Count | 4 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently Bonded Unit Count | 1 |
API Imports and Exports
Importing Country | Total Quantity (KGS) |
Average Price (USD/KGS) |
Number of Transactions |
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Details:
Skinvive™ by Juvéderm® is a smooth, injectable HA gel that contains a small amount of local anesthetic (lidocaine). It improves skin quality in the cheeks by smoothing the skin and increasing hydration.
Lead Product(s): Hyaluronic Acid
Therapeutic Area: Dermatology Brand Name: Skinvive
Study Phase: ApprovedProduct Type: Small molecule
Sponsor: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable May 15, 2023
Lead Product(s) : Hyaluronic Acid
Therapeutic Area : Dermatology
Highest Development Status : Approved
Partner/Sponsor/Collaborator : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
SKINVIVE™ by JUVÉDERM® Receives U.S. FDA Approval
Details : Skinvive™ by Juvéderm® is a smooth, injectable HA gel that contains a small amount of local anesthetic (lidocaine). It improves skin quality in the cheeks by smoothing the skin and increasing hydration.
Brand Name : Skinvive
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 15, 2023
Details:
Juvederm Voluma™ XC (hyaluronic acid) is indicated for deep (subcutaneous and/or supraperiosteal) injection for cheek augmentation to correct age-related volume deficit in the mid-face in adults over the age of 21.
Lead Product(s): Hyaluronic Acid
Therapeutic Area: Dermatology Brand Name: Juvederm Volux XC
Study Phase: ApprovedProduct Type: Small molecule
Sponsor: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable January 18, 2023
Lead Product(s) : Hyaluronic Acid
Therapeutic Area : Dermatology
Highest Development Status : Approved
Partner/Sponsor/Collaborator : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
JUVÉDERM® VOLUX™ XC For Improvement Of Jawline Definition Now Available Nationwide
Details : Juvederm Voluma™ XC (hyaluronic acid) is indicated for deep (subcutaneous and/or supraperiosteal) injection for cheek augmentation to correct age-related volume deficit in the mid-face in adults over the age of 21.
Brand Name : Juvederm Volux XC
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 18, 2023
Details:
Allergan Aesthetics looks to further develop the Hybrid Injectables category by introducing its first dual-effect product, which combines the two active ingredients - hyaluronic acid, a well-known ingredient found in facial fillers and calcium hydroxyapatite in one injection.
Lead Product(s): Hyaluronic Acid,HYDROXYPROPYLMETHYLCELLULOSE
Therapeutic Area: Dermatology Brand Name: HArmonyCa
Study Phase: ApprovedProduct Type: Small molecule
Sponsor: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable March 29, 2022
Lead Product(s) : Hyaluronic Acid,HYDROXYPROPYLMETHYLCELLULOSE
Therapeutic Area : Dermatology
Highest Development Status : Approved
Partner/Sponsor/Collaborator : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Allergan Aesthetics looks to further develop the Hybrid Injectables category by introducing its first dual-effect product, which combines the two active ingredients - hyaluronic acid, a well-known ingredient found in facial fillers and calcium hydroxyapa...
Brand Name : HArmonyCa
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 29, 2022
Details:
JUVÉDERM® VOLBELLA® XC was first FDA–approved in 2016 for use in the lips and perioral rhytids.2 As the category leader, the JUVÉDERM® Collection of Fillers offers the broadest portfolio, and this latest approval marks the sixth approved indication in the U.S.
Lead Product(s): Hyaluronic Acid,Lidocaine
Therapeutic Area: Dermatology Brand Name: Juvéderm Volbella XC
Study Phase: ApprovedProduct Type: Small molecule
Sponsor: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable February 08, 2022
Lead Product(s) : Hyaluronic Acid,Lidocaine
Therapeutic Area : Dermatology
Highest Development Status : Approved
Partner/Sponsor/Collaborator : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
FDA Approves JUVÉDERM® VOLBELLA® XC For Undereye Hollows
Details : JUVÉDERM® VOLBELLA® XC was first FDA–approved in 2016 for use in the lips and perioral rhytids.2 As the category leader, the JUVÉDERM® Collection of Fillers offers the broadest portfolio, and this latest approval marks the sixth approved indicatio...
Brand Name : Juvéderm Volbella XC
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 08, 2022
Details:
JUVÉDERM (Hyaluronic Acid) is indicated for deep (subcutaneous and/or supraperiosteal) injection for cheek augmentation to correct age-related volume deficit in mid-face and for augmentation of chin region to improve chin profile in adults over age of 21.
Lead Product(s): Hyaluronic Acid
Therapeutic Area: Dermatology Brand Name: Juvederm Volux XC
Study Phase: ApprovedProduct Type: Small molecule
Sponsor: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable June 15, 2020
Lead Product(s) : Hyaluronic Acid
Therapeutic Area : Dermatology
Highest Development Status : Approved
Partner/Sponsor/Collaborator : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
FDA Approves JUVÉDERM® VOLUMA™ XC for Enhancement of the Chin Region
Details : JUVÉDERM (Hyaluronic Acid) is indicated for deep (subcutaneous and/or supraperiosteal) injection for cheek augmentation to correct age-related volume deficit in mid-face and for augmentation of chin region to improve chin profile in adults over age of 2...
Brand Name : Juvederm Volux XC
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 15, 2020
Details:
New pre-clinical study showed that Dermial® hyaluronic acid matrix ingredient increased type I collagen production by almost half – an observation not seen with standard hyaluronic acid from fermentation or extraction origin.
Lead Product(s): Hyaluronic Acid,Dermatan Sulfate,Collagen
Therapeutic Area: Dermatology Brand Name: Dermial
Study Phase: PreclinicalProduct Type: Small molecule
Sponsor: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable May 25, 2022
Lead Product(s) : Hyaluronic Acid,Dermatan Sulfate,Collagen
Therapeutic Area : Dermatology
Highest Development Status : Preclinical
Partner/Sponsor/Collaborator : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
New Study Reveals Bioiberica's Dermial® Delivers Superior Benefits for Skin Health
Details : New pre-clinical study showed that Dermial® hyaluronic acid matrix ingredient increased type I collagen production by almost half – an observation not seen with standard hyaluronic acid from fermentation or extraction origin.
Brand Name : Dermial
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 25, 2022
Details:
Apsen’s Motilex HA combines two leading ingredients, b-2Cool native type II collagen and Mobilee, patented ingredient that synergistically combines a high concentration of hyaluronic acid with polysaccharides and collagen, to effectively maintain joint function.
Lead Product(s): Hyaluronic Acid,Type II Collagen
Therapeutic Area: Musculoskeletal Brand Name: Motilex HA
Study Phase: ApprovedProduct Type: Small molecule
Sponsor: Apsen
Deal Size: Undisclosed Upfront Cash: Undisclosed
Deal Type: Partnership April 26, 2021
Lead Product(s) : Hyaluronic Acid,Type II Collagen
Therapeutic Area : Musculoskeletal
Highest Development Status : Approved
Partner/Sponsor/Collaborator : Apsen
Deal Size : Undisclosed
Deal Type : Partnership
Bioiberica and Apsen Reinforce Partnership with New Holistic Mobility Product–Motilex HA
Details : Apsen’s Motilex HA combines two leading ingredients, b-2Cool native type II collagen and Mobilee, patented ingredient that synergistically combines a high concentration of hyaluronic acid with polysaccharides and collagen, to effectively maintain joint...
Brand Name : Motilex HA
Molecule Type : Small molecule
Upfront Cash : Undisclosed
April 26, 2021
Details:
The study, conducted in a rabbit model of osteoarthritis, set out to evaluate the effects of b-2Cool native type II collagen in combination with CS b-Bioactive chondroitin sulphate, glucosamine hydrochloride and Mobilee® which is a rooster comb extract rich in hyaluronic acid.
Lead Product(s): Undenatured Type II Collagen,Chondroitin Sulfate Sodium,Hyaluronic Acid
Therapeutic Area: Musculoskeletal Brand Name: Mobilee
Study Phase: ApprovedProduct Type: Large molecule
Sponsor: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable September 07, 2020
Lead Product(s) : Undenatured Type II Collagen,Chondroitin Sulfate Sodium,Hyaluronic Acid
Therapeutic Area : Musculoskeletal
Highest Development Status : Approved
Partner/Sponsor/Collaborator : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
New Study Further Validates Bioiberica’s B-2cool® Native Type II Collagen as Trusted Source for...
Details : The study, conducted in a rabbit model of osteoarthritis, set out to evaluate the effects of b-2Cool native type II collagen in combination with CS b-Bioactive chondroitin sulphate, glucosamine hydrochloride and Mobilee® which is a rooster comb extract ...
Brand Name : Mobilee
Molecule Type : Large molecule
Upfront Cash : Not Applicable
September 07, 2020
Details:
B-2Cool (Bioiberica’s native type II collagen) is an innovative ingredient, has been shown in four scientific studies to help maintain good joint health at a very low daily dose.
Lead Product(s): Undenatured Type II Collagen,Harpagophytum Procumbens Extract,Hyaluronic Acid
Therapeutic Area: Musculoskeletal Brand Name: Colnatur Forte
Study Phase: ApprovedProduct Type: Large molecule
Sponsor: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable July 15, 2020
Lead Product(s) : Undenatured Type II Collagen,Harpagophytum Procumbens Extract,Hyaluronic Acid
Therapeutic Area : Musculoskeletal
Highest Development Status : Approved
Partner/Sponsor/Collaborator : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Laboratorios Ordesa Incorporates B-2cool®, Bioiberica’s Native Type II Collagen, in Its New Col...
Details : B-2Cool (Bioiberica’s native type II collagen) is an innovative ingredient, has been shown in four scientific studies to help maintain good joint health at a very low daily dose.
Brand Name : Colnatur Forte
Molecule Type : Large molecule
Upfront Cash : Not Applicable
July 15, 2020
Details:
Bloomsurfact EncapCare (hyaluronic acid) is an emulsion solution for effective anti-aging skin rejuvenation & ensures high bioavailability & low irritation making it more friendly for sensitive skin.
Lead Product(s): Hyaluronic Acid
Therapeutic Area: Dermatology Brand Name: Bloomsurfact EncapCare
Study Phase: ApprovedProduct Type: Small molecule
Sponsor: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable December 12, 2023
Lead Product(s) : Hyaluronic Acid
Therapeutic Area : Dermatology
Highest Development Status : Approved
Partner/Sponsor/Collaborator : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
SCC77: Bloomage Bloomsurfact EncapCare RP Ensures 99% Dispersion of Anti-aging Ingredient
Details : Bloomsurfact EncapCare (hyaluronic acid) is an emulsion solution for effective anti-aging skin rejuvenation & ensures high bioavailability & low irritation making it more friendly for sensitive skin.
Brand Name : Bloomsurfact EncapCare
Molecule Type : Small molecule
Upfront Cash : Not Applicable
December 12, 2023
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