List of Related Excipient Companies and Suppliers of Hyaluronic Acid by Actylis on PharmaCompass.com

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Synopsis

ACTIVE PHARMA INGREDIENTS

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CEP/COS

CEP/COS Certifications

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EU WC

EU WC

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KDMF

KDMF

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VMF

NDC API

API REF. PRICE (USD/KG)

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0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

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FDA Orange Book

FDA (Orange Book)

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Canada

Canada

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Australia

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

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USP

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Stock Recap #PipelineProspector

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GLOBAL SALES INFORMATION

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28 RELATED EXCIPIENT COMPANIES

56EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: Ncgc00167966-01, Dsstox_cid_26750, Dsstox_rid_81875, Dsstox_gsid_46750, Chembl1874250, Dtxsid20858848
Molecular Formula
C28H44N2O23
Molecular Weight
776.6  g/mol
InChI Key
KIUKXJAPPMFGSW-YXBJCWEESA-N

Hyaluronic Acid
1 2D Structure

Hyaluronic Acid

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2S,4S,5R,6S)-6-[(2S,3R,5S,6R)-3-acetamido-2-[(3S,4R,5R,6R)-6-[(3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid
2.1.2 InChI
InChI=1S/C28H44N2O23/c1-5(33)29-9-18(11(35)7(3-31)47-25(9)46)49-28-17(41)15(39)20(22(53-28)24(44)45)51-26-10(30-6(2)34)19(12(36)8(4-32)48-26)50-27-16(40)13(37)14(38)21(52-27)23(42)43/h7-22,25-28,31-32,35-41,46H,3-4H2,1-2H3,(H,29,33)(H,30,34)(H,42,43)(H,44,45)/t7-,8-,9-,10-,11-,12-,13+,14?,15-,16-,17-,18-,19?,20+,21+,22?,25?,26+,27+,28-/m1/s1
2.1.3 InChI Key
KIUKXJAPPMFGSW-YXBJCWEESA-N
2.1.4 Canonical SMILES
CC(=O)NC1C(C(C(OC1O)CO)O)OC2C(C(C(C(O2)C(=O)O)OC3C(C(C(C(O3)CO)O)OC4C(C(C(C(O4)C(=O)O)O)O)O)NC(=O)C)O)O
2.1.5 Isomeric SMILES
CC(=O)N[C@@H]1[C@H]([C@@H]([C@H](OC1O)CO)O)O[C@H]2[C@@H]([C@H]([C@@H](C(O2)C(=O)O)O[C@H]3[C@@H](C([C@@H]([C@H](O3)CO)O)O[C@@H]4[C@@H]([C@H](C([C@H](O4)C(=O)O)O)O)O)NC(=O)C)O)O
2.2 Synonyms
2.2.1 Depositor-Supplied Synonyms

1. Ncgc00167966-01

2. Dsstox_cid_26750

3. Dsstox_rid_81875

4. Dsstox_gsid_46750

5. Chembl1874250

6. Dtxsid20858848

7. Tox21_112595

8. Akos015960603

9. Ac-11740

10. Ac-31947

11. Cas-9004-61-9

12. (4xi)-alpha-d-xylo-hexopyranuronosyl-(1->3)-(3xi)-2-(acetylamino)-2-deoxy-beta-d-ribo-hexopyranosyl-(1->4)-(5xi)-beta-d-xylo-hexopyranuronosyl-(1->3)-2-(acetylamino)-2-deoxy-d-glucopyranose

2.2.2 Other Synonyms

1. Hyaluronan

2.3 Create Date
2008-02-29
3 Chemical and Physical Properties
Molecular Weight 776.6 g/mol
Molecular Formula C28H44N2O23
XLogP3-7.4
Hydrogen Bond Donor Count14
Hydrogen Bond Acceptor Count23
Rotatable Bond Count12
Exact Mass776.23348565 g/mol
Monoisotopic Mass776.23348565 g/mol
Topological Polar Surface Area400 Ų
Heavy Atom Count53
Formal Charge0
Complexity1300
Isotope Atom Count0
Defined Atom Stereocenter Count16
Undefined Atom Stereocenter Count4
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

API SUPPLIERS

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01

Bloomage Biotechnology Corp., Ltd

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothBloomage is a one-stop source for CEP Sodium Hyaluronate and Hyaluronic Acid// FDA-inspected & GMP-certified.

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Digital Content Digital Content
USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
Bloomage Company Banner

02

Kewpie Corporation

Japan

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothKewpie is your partner for Sodium Hyaluronate & Hyaluronic Acid// CEP, USDMF, KDMF & JDMF registered.

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Digital Content Digital Content
USDMF CEP/COS JDMF arrow-down EU-WC NDC KDMF VMF Others AUDIT
Kewpie Company Banner

03

HTL Biotechnology

France

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothHTL Biotechnology is the world leader in the responsible development and production of pharmaceutical-grade biopolymers.

Flag France
Digital Content Digital Content
USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
HTL Biotechnology Biopolymer

04

Shandong Topscience Biotech Co., L...

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothTopscience Biotech specializes in R&D, production, sales of Sodium Hyaluronate, focusing on Cosmetics, Medical, Pharmaceutical Grade HA

Flag China
Digital Content Digital Content
USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
Shandong Topscience Biotech

05

LGM Pharma

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothLGM Pharma accelerates & optimizes the new product pathway from early development through commercialization.

Flag U.S.A
Digital Content Digital Content
USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
LGM Pharma CB

06

Pharm-RX Chemical

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothPharm-Rx is a reputed global importer and distributor of pharmaceutical active ingredients.

Flag U.S.A
Digital Content Digital Content
USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
Pharm RX

07

Aroma-Zone

France

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothAroma-Zone, your go-to for essential oils, hydrosols, and natural facial serums.

Flag France
Digital Content Digital Content
USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
Aroma-Zone

08

Shanghai Minbiotech

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothShanghai Minbiotech is the leading producer of biopharmaceuticals and a variety of high-end generic & innovative drugs.

Flag China
Digital Content Digital Content
USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
Shanghai Minbiotech CB

09

Basic Nutrition

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothBasic Nutrition, your expert for sourcing from China, India and Europe.

Flag China
Digital Content Digital Content
USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
Basic Nutrition Company Banner

10

Merck & Co

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

ASC 2024
Not Confirmed
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Merck & Co

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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ASC 2024
Not Confirmed
USDMF Inactive-api CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
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Listed Suppliers

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01

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothBloomage is a one-stop source for CEP Sodium Hyaluronate and Hyaluronic Acid// FDA-inspected & GMP-certified.

Flag China
Digital Content Digital Content

Hyaluronic Acid

About the Company : Bloomage Biotechnology Corporation Limited, formerly Bloomage Freda Biopharm, was established by Bloomage International Investment Group. It is a global leader in bioactive materia...

Bloomage Biotechnology Corporation Limited, formerly Bloomage Freda Biopharm, was established by Bloomage International Investment Group. It is a global leader in bioactive materials like mucopolysaccharides, proteins, peptides, amino acids, & natural compounds. In the 1990s, it became the first company in China to develop fermentation-based sodium hyaluronate. With around 200 specifications of hyaluronic acid, it caters to the pharmaceutical, medical devices, cosmetics, & functional food sectors. For pharma raw materials, Bloomage offers innovative solutions in aesthetics, dermatology, ophthalmology, orthopedics, & regenerative medicines.
Bloomage Company Banner

02

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothKewpie is your partner for Sodium Hyaluronate & Hyaluronic Acid// CEP, USDMF, KDMF & JDMF registered.

Flag Japan
Digital Content Digital Content

Hyaluronic Acid

About the Company : Kewpie first developed Sodium hyaluronate in 1983 and is currently the leading Japanese manufacturer of pharmaceutical grade Sodium hyaluronate used as an API and pharmaceutical ex...

Kewpie first developed Sodium hyaluronate in 1983 and is currently the leading Japanese manufacturer of pharmaceutical grade Sodium hyaluronate used as an API and pharmaceutical excipients. Its Sodium hyaluronate is suitable for injections, eye drops and external preparations. Its pharmaceutical grade Sodium hyaluronate (Hyaluronic acid) is manufactured at its factory near Tokyo under strict regulations. Since 2016, Kewpie has developed and manufactured medical devices using Sodium hyaluronate. Its R&D team can also provide Sodium hyaluronate derivatives as per clients’ needs. Kewpie exports Sodium hyaluronate to over 30 countries.
Kewpie Company Banner

03

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothHTL Biotechnology is the world leader in the responsible development and production of pharmaceutical-grade biopolymers.

Flag France
Digital Content Digital Content

Hyaluronic Acid

About the Company : HTL is a biotechnology company pioneering the development and production of pharmaceutical-grade hyaluronic acid (Hyaluronan) and other functional biopolymers such as PDRN and PN, ...

HTL is a biotechnology company pioneering the development and production of pharmaceutical-grade hyaluronic acid (Hyaluronan) and other functional biopolymers such as PDRN and PN, designed to improve people's lives. HTL is the only Hyaluronic Acid producer exclusively producing injectable grade. Our clients develop products for dermatology, aesthetics, ophthalmology, rheumatology, urology and more. This is how we contribute to changing the lives of millions of people around the world.
HTL Biotechnology Biopolymer

04

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothTopscience Biotech specializes in R&D, production, sales of Sodium Hyaluronate, focusing on Cosmetics, Medical, Pharmaceutical Grade HA

Flag China
Digital Content Digital Content

Hyaluronic Acid

About the Company : Established in 2005, Topscience located in Lanshan, Rizhao of PRC and covers an area of 100,000m². Products include Sodium Hyaluronate, Chondroitin Sulfate, Alpha-Arbutin, Ascorby...

Established in 2005, Topscience located in Lanshan, Rizhao of PRC and covers an area of 100,000m². Products include Sodium Hyaluronate, Chondroitin Sulfate, Alpha-Arbutin, Ascorbyl Glucoside, Sulglycotide etc. We have GMP certificate, Drug manufacturing Certificate, CEP of Sodium Hyaluronate, Written Confirmation, Certificate of DMF Registration, Halal, Kosher etc. Sodium Hyaluronate API includes Injection grade, Eye-Drop grade and Excipients grade. The bacterial endotoxin of Sodium Hyaluronate(Injection Grade) is less than 0.001 IU/mg, which is much lower than European Pharmacopoeia current edition 50 times.
Shandong Topscience Biotech

05

LGM Pharma

U.S.A
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothLGM Pharma accelerates & optimizes the new product pathway from early development through commercialization.

Flag U.S.A
Digital Content Digital Content

Hyaluronic Acid

About the Company : LGM Pharma is a global leader in sourcing hard-to-find APIs and intermediates for the pharmaceutical and biotech industries. LGM is also a full service CDMO providing formulation, ...

LGM Pharma is a global leader in sourcing hard-to-find APIs and intermediates for the pharmaceutical and biotech industries. LGM is also a full service CDMO providing formulation, analytical method development and testing, and commercial manufacturing. LGM Pharma offers custom API synthesis, analytical development, and regulatory services. With a network of over 300 accredited CGMP manufacturing partners, LGM provides unparalleled supply chain security. And, with over 100,000 square feet of FDA-inspected cGMP manufacturing and warehouse capacity, LGM Pharma provides a one-stop solution for solid dose, powder, semi-solid and liquid drugs.
LGM Pharma CB

06

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothPharm-Rx is a reputed global importer and distributor of pharmaceutical active ingredients.

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Digital Content Digital Content

Hyaluronic Acid

About the Company : Pharm-Rx has earned an outstanding reputation since its establishment in 1991, serving as a reputable importer and distributor of active ingredients to the pharmaceutical, nutritio...

Pharm-Rx has earned an outstanding reputation since its establishment in 1991, serving as a reputable importer and distributor of active ingredients to the pharmaceutical, nutritional supplement, and food industries. The company maintains an exceptionally selective approach to its suppliers, personally visiting manufacturers overseas to ensure the highest standards. The sustained growth of Pharm-Rx can be attributed to its steadfast commitment to three core values: quality ingredients, competitive pricing, and unparalleled customer service.
Pharm RX

07

Aroma-Zone

France
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothAroma-Zone, your go-to for essential oils, hydrosols, and natural facial serums.

Flag France
Digital Content Digital Content

Hyaluronic Acid

About the Company : Aroma-Zone project was conceived with a simple aim to share our expertise and enthusiasm for essential oils, the potent essences of plant life. We are dedicated to providing transp...

Aroma-Zone project was conceived with a simple aim to share our expertise and enthusiasm for essential oils, the potent essences of plant life. We are dedicated to providing transparent information about our products, including their origins, production methods, and benefits. Our detailed technical guides empower you to make informed choices that align with your preferences. Aroma-Zone has been committed to making 100% natural skincare accessible to as many people as possible, ensuring our presence both in physical stores and online for your convenience.
Aroma-Zone

08

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothShanghai Minbiotech is the leading producer of biopharmaceuticals and a variety of high-end generic & innovative drugs.

Flag China
Digital Content Digital Content

Hyaluronic Acid

About the Company : ​Headquartered in Fengxian District, Shanghai Minbiotch Co., Ltd. is a company specializing in the R&D and production of advanced pharmaceutical intermediates and biological APIs...

​Headquartered in Fengxian District, Shanghai Minbiotch Co., Ltd. is a company specializing in the R&D and production of advanced pharmaceutical intermediates and biological APIs. There are more than 1000 square meters of R&D centers in Nantong, Jiangsu and Jinan, Shandong, with more than 13,000㎡ of production sites. While supplying products to customers, the company also provides services such as technology development, technology transfer and technology exchange, aiming to provide customers with comprehensive supply and solutions in the biomedical industry.
Shanghai Minbiotech CB

09

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothBasic Nutrition, your expert for sourcing from China, India and Europe.

Flag China
Digital Content Digital Content

Hyaluronic Acid

About the Company : As an ISO9001, ISO22000 certificated supplier, Basic Nutrition supply high-quality ingredients for nutraceuticals. We can offer a range of products from small to large quantites: h...

As an ISO9001, ISO22000 certificated supplier, Basic Nutrition supply high-quality ingredients for nutraceuticals. We can offer a range of products from small to large quantites: herbal extract, amino acid, vitamin, etc. Featured products: cranberry extract, rhidiola extract, Q10, hyaluronic acid, cysteine (non-animals), glutathoninr, orgaic products like organic spirulina, organic red yeast rice powder, etc.
Basic Nutrition Company Banner

10

PK Components

Poland
ASC 2024
Not Confirmed
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PK Components

Poland
arrow
ASC 2024
Not Confirmed

Hyaluronic Acid

About the Company : PK Components is a Polish distributor of raw materials for the production of dietary supplements and for the food industry. Our hallmark is a stable market position, customer trust...

PK Components is a Polish distributor of raw materials for the production of dietary supplements and for the food industry. Our hallmark is a stable market position, customer trust, and a comprehensive offer combining consulting and sales into a reliable business partnership. We supply the highest quality raw materials for the production of dietary supplements and food.
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API Reference Price

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15-Mar-2021
01-Aug-2024
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