Find Tussionex manufacturers, exporters & distributors on PharmaCompass

PharmaCompass

Synopsis

Related ProductsRelated Products

Synopsis

ACTIVE PHARMA INGREDIENTS

0

API Suppliers

API Suppliers

0

USDMF

US DMFs Filed

0

CEP/COS

CEP/COS Certifications

0

JDMF

JDMFs Filed

0

EU WC

EU WC

0

KDMF

KDMF

0

NDC API

NDC API

0

VMF

NDC API

0

Listed Suppliers

Other Suppliers

API REF. PRICE (USD/KG)

$
$ 0

MARKET PLACE

0

API

0

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

0

Europe

Europe

0

Canada

Canada

0

Australia

Australia

0

South Africa

South Africa

0

Listed Dossiers

Listed Dossiers

0 DRUGS IN DEVELOPMENT

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

0

EDQM

0

USP

0

JP

0

Others

PATENTS & EXCLUSIVITIES

0

US Patents

0

US Exclusivities

0

Health Canada Patents

DIGITAL CONTENT

0

Data Compilation #PharmaFlow

0

Stock Recap #PipelineProspector

0

Weekly News Recap #Phispers

GLOBAL SALES INFORMATION

US Medicaid

NA

Annual Reports

NA

Finished Drug Prices

NA

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown
read-moreClick the button for full data set
Also known as: Chlorpheniramine mixture with hydrocodone, 131219-97-1, Vituz, Tuzistra xr, Tussionex pennkinetic, S-t forte 2
Molecular Formula
C34H40ClN3O3
Molecular Weight
574.1  g/mol
InChI Key
UUEZOEBHFHYMGR-RNWHKREASA-N

Tussionex
1 2D Structure

Tussionex

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(4R,4aR,7aR,12bS)-9-methoxy-3-methyl-1,2,4,4a,5,6,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one;3-(4-chlorophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amine
2.1.2 InChI
InChI=1S/C18H21NO3.C16H19ClN2/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19;1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13/h3,6,11-12,17H,4-5,7-9H2,1-2H3;3-9,11,15H,10,12H2,1-2H3/t11-,12+,17-,18-;/m0./s1
2.1.3 InChI Key
UUEZOEBHFHYMGR-RNWHKREASA-N
2.1.4 Canonical SMILES
CN1CCC23C4C1CC5=C2C(=C(C=C5)OC)OC3C(=O)CC4.CN(C)CCC(C1=CC=C(C=C1)Cl)C2=CC=CC=N2
2.1.5 Isomeric SMILES
CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)OC)O[C@H]3C(=O)CC4.CN(C)CCC(C1=CC=C(C=C1)Cl)C2=CC=CC=N2
2.2 Synonyms
2.2.1 Depositor-Supplied Synonyms

1. Chlorpheniramine Mixture With Hydrocodone

2. 131219-97-1

3. Vituz

4. Tuzistra Xr

5. Tussionex Pennkinetic

6. S-t Forte 2

7. Tussicaps Extended-release

8. Tussionex

9. Chlorpheniramine / Hydrocodone

10. Chlorpheniramine Polistirex / Hydrocodone Polistirex

11. Chlorpheniramine Polistirex And Hydrocodone Polistirex

12. Hydrocodone Polistirex And Chlorpheniramine Polistirex

13. Schembl2522788

14. Dtxsid50156960

15. Hydrocodone Conbination Product 15 Mg/du

2.3 Create Date
2009-08-20
3 Chemical and Physical Properties
Molecular Weight 574.1 g/mol
Molecular Formula C34H40ClN3O3
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Exact Mass573.2758198 g/mol
Monoisotopic Mass573.2758198 g/mol
Topological Polar Surface Area54.9 Ų
Heavy Atom Count41
Formal Charge0
Complexity758
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Drug and Medication Information
4.1 Drug Information
1 of 6  
Drug NameHydrocodone polistirex and chlorpheniramine polistirex
Active IngredientChlorpheniramine polistirex; hydrocodone polistirex
Dosage FormSuspension, extended release
RouteOral
Strengtheq 10mg bitartrate/5ml; eq 8mg maleate/5ml
Market StatusPrescription
CompanyTris Pharma

2 of 6  
Drug NameTussicaps
Active IngredientChlorpheniramine polistirex; hydrocodone polistirex
Dosage FormCapsule, extended release
RouteOral
Strengtheq 10mg bitartrate; eq 5mg bitartrate; eq 4mg maleate; eq 8mg maleate
Market StatusPrescription
CompanyEcr Pharma

3 of 6  
Drug NameTussionex pennkinetic
PubMed HealthHydrocodone and Chlorpheniramine Polistirex (Oral route)
Drug ClassesAntitussive, Opioid/Antihistamine Combination, Chlorpheniramine
Active IngredientChlorpheniramine polistirex; hydrocodone polistirex
Dosage FormSuspension, extended release
RouteOral
Strengtheq 10mg bitartrate/5ml; eq 8mg maleate/5ml
Market StatusPrescription
CompanyUcb

4 of 6  
Drug NameHydrocodone polistirex and chlorpheniramine polistirex
Active IngredientChlorpheniramine polistirex; hydrocodone polistirex
Dosage FormSuspension, extended release
RouteOral
Strengtheq 10mg bitartrate/5ml; eq 8mg maleate/5ml
Market StatusPrescription
CompanyTris Pharma

5 of 6  
Drug NameTussicaps
Active IngredientChlorpheniramine polistirex; hydrocodone polistirex
Dosage FormCapsule, extended release
RouteOral
Strengtheq 10mg bitartrate; eq 5mg bitartrate; eq 4mg maleate; eq 8mg maleate
Market StatusPrescription
CompanyEcr Pharma

6 of 6  
Drug NameTussionex pennkinetic
PubMed HealthHydrocodone and Chlorpheniramine Polistirex (Oral route)
Drug ClassesAntitussive, Opioid/Antihistamine Combination, Chlorpheniramine
Active IngredientChlorpheniramine polistirex; hydrocodone polistirex
Dosage FormSuspension, extended release
RouteOral
Strengtheq 10mg bitartrate/5ml; eq 8mg maleate/5ml
Market StatusPrescription
CompanyUcb

5 Pharmacology and Biochemistry
5.1 FDA Pharmacological Classification
5.1.1 Pharmacological Classes
Histamine-1 Receptor Antagonist [EPC]; Opioid Agonist [EPC]; Opioid Agonists [MoA]; Histamine H1 Receptor Antagonists [MoA]

Digital Content read-more

Create Content with PharmaCompass, ask us

NEWS #PharmaBuzz

read-more
read-more

ABOUT THIS PAGE

Ask Us for Pharmaceutical Supplier and Partner
Ask Us, Find A Supplier / Partner
No Commissions, No Strings Attached, Get Connected for FREE

What are you looking for?

How can we help you?

The request can't be empty

Please read our Privacy Policy carefully

You must agree to the privacy policy

The name can't be empty
The company can't be empty.
The email can't be empty Please enter a valid email.
The mobile can't be empty