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    Chemistry

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    Also known as: Ncgc00018263-02, Chembl67128, Chebi:181452, Akos015917554
    Molecular Formula
    C26H38O6
    Molecular Weight
    446.6  g/mol
    InChI Key
    FZCHYNWYXKICIO-MDDFJDPJSA-N
    Hydrocortisone Valerate
    1 2D Structure

    Hydrocortisone Valerate

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    [(17R)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] pentanoate
    2.1.2 InChI
    InChI=1S/C26H38O6/c1-4-5-6-22(31)32-26(21(30)15-27)12-10-19-18-8-7-16-13-17(28)9-11-24(16,2)23(18)20(29)14-25(19,26)3/h13,18-20,23,27,29H,4-12,14-15H2,1-3H3/t18?,19?,20?,23?,24?,25?,26-/m0/s1
    2.1.3 InChI Key
    FZCHYNWYXKICIO-MDDFJDPJSA-N
    2.1.4 Canonical SMILES
    CCCCC(=O)OC1(CCC2C1(CC(C3C2CCC4=CC(=O)CCC34C)O)C)C(=O)CO
    2.1.5 Isomeric SMILES
    CCCCC(=O)O[C@@]1(CCC2C1(CC(C3C2CCC4=CC(=O)CCC34C)O)C)C(=O)CO
    2.2 Synonyms
    2.2.1 Depositor-Supplied Synonyms

    1. Ncgc00018263-02

    2. Chembl67128

    3. Chebi:181452

    4. Akos015917554

    2.3 Create Date
    2005-08-08
    3 Chemical and Physical Properties
    Molecular Weight 446.6 g/mol
    Molecular Formula C26H38O6
    XLogP33.8
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count6
    Rotatable Bond Count7
    Exact Mass446.26683893 g/mol
    Monoisotopic Mass446.26683893 g/mol
    Topological Polar Surface Area101 Ų
    Heavy Atom Count32
    Formal Charge0
    Complexity832
    Isotope Atom Count0
    Defined Atom Stereocenter Count1
    Undefined Atom Stereocenter Count6
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 2  
    Drug NameHydrocortisone valerate
    PubMed HealthHydrocortisone Valerate (Topical application route)
    Drug ClassesCorticosteroid, Intermediate, Hydrocortisone
    Active IngredientHydrocortisone valerate
    Dosage FormOintment; Cream
    RouteTopical
    Strength0.2%
    Market StatusPrescription
    CompanyTaro; Perrigo New York

    2 of 2  
    Drug NameHydrocortisone valerate
    PubMed HealthHydrocortisone Valerate (Topical application route)
    Drug ClassesCorticosteroid, Intermediate, Hydrocortisone
    Active IngredientHydrocortisone valerate
    Dosage FormOintment; Cream
    RouteTopical
    Strength0.2%
    Market StatusPrescription
    CompanyTaro; Perrigo New York

    USDMF

    read-more
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    01

    Lupin Ltd

    India

    USDMF

    arrow
    AES 2024
    Not Confirmed

    01

    Lupin Ltd

    India
    arrow
    AES 2024
    Not Confirmed

    GDUFA

    DMF Review : Complete

    Rev. Date : 2017-03-02

    Pay. Date : 2017-01-09

    DMF Number : 31143

    Submission : 2016-12-30

    Status : Active

    Type : II

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    02

    AES 2024
    Not Confirmed

    02

    Symbiotica Speciality Ingredients Sd...

    Malaysia
    arrow
    AES 2024
    Not Confirmed

    GDUFA

    DMF Review : Complete

    Rev. Date : 2017-11-07

    Pay. Date : 2017-06-05

    DMF Number : 31423

    Submission : 2017-02-01

    Status : Active

    Type : II

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    03

    AES 2024
    Not Confirmed

    03

    Taro Pharmaceutical Industries Ltd

    U.S.A
    arrow
    AES 2024
    Not Confirmed

    GDUFA

    DMF Review : N/A

    Rev. Date :

    Pay. Date :

    DMF Number : 13921

    Submission : 1998-12-30

    Status : Active

    Type : II

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    04

    Trifarma Spa

    Italy

    USDMF

    arrow
    AES 2024
    Not Confirmed

    04

    Trifarma Spa

    Italy
    arrow
    AES 2024
    Not Confirmed

    GDUFA

    DMF Review : Complete

    Rev. Date : 2019-10-07

    Pay. Date : 2019-04-29

    DMF Number : 33334

    Submission : 2018-12-19

    Status : Active

    Type : II

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    API Reference Price

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    [{"dataSource":"API Import","activeIngredients":"HYDROCORTISONE VALERATE","year":"2021","qtr":"Q2","strtotime":1620325800,"product":"HYDROCORTISONE VALERATE USP, BATCH NO HCV 001\/0421","address":"B\/2 MAHALAXMI CHAMBERS22 BHULABHAI DESAI ROAD","city":"MUMBAI. MAHARASHTRA","supplier":"SYMBIOTICA SPECIALITY INGREDIENTS ","supplierCountry":"MALAYSIA","foreign_port":"PENANG","customer":"GLENMARK PHARMACEUTICALS","customerCountry":"INDIA","quantity":"3.00","actualQuantity":"3","unit":"KGS","unitRateFc":"4500","totalValueFC":"13776.6","currency":"USD","unitRateINR":"336375","date":"07-May-2021","totalValueINR":"1009125","totalValueInUsd":"13776.6","indian_port":"DELHI AIR","hs_no":"29201990","bill_no":"3862330","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"MALAYSIA","selfForZScoreResived":"Pharma Grade","supplierPort":"PENANG","supplierAddress":"","customerAddress":"B\/2 MAHALAXMI CHAMBERS22 BHULABHAI DESAI ROAD"}]
    07-May-2021
    07-May-2021
    KGS
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    Average Price (USD/KGS)

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    Quantity (KGS) & Unit rate (USD/KGS) over time

    API Imports and Exports

    Importing Country Total Quantity
    (KGS)    		 Average Price
    (USD/KGS)    		 Number of Transactions

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