Find Hydroxydopamine Hydrobromide manufacturers, exporters & distributors on PharmaCompass

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Chemistry

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Also known as: 636-00-0, Oxidopamine hydrobromide, Oxidopamine (hydrobromide), 6-hydroxydopamine hbr, 6-ohda, 2,4,5-trihydroxyphenethylamine hydrobromide
Molecular Formula
C8H12BrNO3
Molecular Weight
250.09  g/mol
InChI Key
MLACDGUOKDOLGC-UHFFFAOYSA-N
FDA UNII
TWC1D4W0WB

Hydroxydopamine Hydrobromide
A neurotransmitter analogue that depletes noradrenergic stores in nerve endings and induces a reduction of dopamine levels in the brain. Its mechanism of action is related to the production of cytolytic free-radicals.
1 2D Structure

Hydroxydopamine Hydrobromide

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
5-(2-aminoethyl)benzene-1,2,4-triol;hydrobromide
2.1.2 InChI
InChI=1S/C8H11NO3.BrH/c9-2-1-5-3-7(11)8(12)4-6(5)10;/h3-4,10-12H,1-2,9H2;1H
2.1.3 InChI Key
MLACDGUOKDOLGC-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1=C(C(=CC(=C1O)O)O)CCN.Br
2.2 Other Identifiers
2.2.1 UNII
TWC1D4W0WB
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 6 Hydroxydopamine

2. 6-hydroxydopamine

3. 6-ohda

4. Hydrobromide, Oxidopamine

5. Hydrochloride, Oxidopamine

6. Oxidopamine

7. Oxidopamine Hydrobromide

8. Oxidopamine Hydrochloride

2.3.2 Depositor-Supplied Synonyms

1. 636-00-0

2. Oxidopamine Hydrobromide

3. Oxidopamine (hydrobromide)

4. 6-hydroxydopamine Hbr

5. 6-ohda

6. 2,4,5-trihydroxyphenethylamine Hydrobromide

7. 5-(2-aminoethyl)benzene-1,2,4-triol Hydrobromide

8. 6-ohda Hbr

9. Mfcd00012894

10. Twc1d4w0wb

11. 2-(2,4,5-trihydroxyphenyl)ethylamine Hydrobromide

12. 1,2,4-benzenetriol, 5-(2-aminoethyl)-, Hydrobromide

13. 6-hydroxydopamine Hydrobromide;6-ohda Hydrobromide

14. Nsc-238469

15. 636-00-0 (hbr)

16. 6-hydroxydopamine Hydrogen Bromide

17. Mls002207128

18. 2,5-dihydroxytyramine Hydrobromide

19. Smr001306725

20. Einecs 211-247-0

21. Unii-twc1d4w0wb

22. Nsc 238469

23. 5-(2-aminoethyl)-4-hydroxypyrocatechol Hydrobromide

24. 5-(2-aminoethyl)benzene-1,2,4-triol;hydrobromide

25. 6-ohda Hydrobromide

26. 6-hydroxydopamine.hydrobromide

27. Schembl738049

28. 4-chlorobenzenecarbaldehydeoxime

29. Chembl1718398

30. Hy-b1081a

31. Dtxsid30212972

32. Wln: Z2r Bq Dq Eq &eh

33. Bcp25700

34. Ex-a4152

35. 6-hydroxydopamine Hydrobromide, 95%

36. Nsc238469

37. S5324

38. Akos015916618

39. Ccg-266959

40. Cs-5966

41. As-40064

42. Sy102034

43. Db-054509

44. B7099

45. Ft-0632700

46. M01851

47. 6-ohda Hydrobromide6-hydroxydopamine Hydrobromide

48. A935047

49. 1,4-benzenetriol, 5-(2-aminoethyl)-, Hydrobromide

50. 5-(2-aminoethyl)-1,2,4-benzenetriol Hydrobromide

51. 6-hydroxydopamine Hydrobromide, >=90% (hplc), Solid

52. Q27290460

53. 1,2,4-benzenetriol, 5-(2-aminoethyl)-, Hydrobromide (1:1)

54. 6-ohda Hbr; 6 Ohda Hbr;oxidopamine Hydrobromide; 6-hydroxydopamine Hbr

55. 6-hydroxydopamine Hydrobromide, Contains Ascorbic Acid As Stabilizer, >=98% (hplc)

2.4 Create Date
2005-07-19
3 Chemical and Physical Properties
Molecular Weight 250.09 g/mol
Molecular Formula C8H12BrNO3
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Exact Mass249.00006 g/mol
Monoisotopic Mass249.00006 g/mol
Topological Polar Surface Area86.7 Ų
Heavy Atom Count13
Formal Charge0
Complexity142
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Sympatholytics

Drugs that inhibit the actions of the sympathetic nervous system by any mechanism. The most common of these are the ADRENERGIC ANTAGONISTS and drugs that deplete norepinephrine or reduce the release of transmitters from adrenergic postganglionic terminals (see ADRENERGIC AGENTS). Drugs that act in the central nervous system to reduce sympathetic activity (e.g., centrally acting alpha-2 adrenergic agonists, see ADRENERGIC ALPHA-AGONISTS) are included here. (See all compounds classified as Sympatholytics.)


Adrenergic Agents

Drugs that act on adrenergic receptors or affect the life cycle of adrenergic transmitters. Included here are adrenergic agonists and antagonists and agents that affect the synthesis, storage, uptake, metabolism, or release of adrenergic transmitters. (See all compounds classified as Adrenergic Agents.)


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ABOUT THIS PAGE

Hydroxydopamine Hydrobromide Manufacturers

A Hydroxydopamine Hydrobromide manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Hydroxydopamine Hydrobromide, including repackagers and relabelers. The FDA regulates Hydroxydopamine Hydrobromide manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Hydroxydopamine Hydrobromide API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Hydroxydopamine Hydrobromide Suppliers

A Hydroxydopamine Hydrobromide supplier is an individual or a company that provides Hydroxydopamine Hydrobromide active pharmaceutical ingredient (API) or Hydroxydopamine Hydrobromide finished formulations upon request. The Hydroxydopamine Hydrobromide suppliers may include Hydroxydopamine Hydrobromide API manufacturers, exporters, distributors and traders.

click here to find a list of Hydroxydopamine Hydrobromide suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Hydroxydopamine Hydrobromide USDMF

A Hydroxydopamine Hydrobromide DMF (Drug Master File) is a document detailing the whole manufacturing process of Hydroxydopamine Hydrobromide active pharmaceutical ingredient (API) in detail. Different forms of Hydroxydopamine Hydrobromide DMFs exist exist since differing nations have different regulations, such as Hydroxydopamine Hydrobromide USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Hydroxydopamine Hydrobromide DMF submitted to regulatory agencies in the US is known as a USDMF. Hydroxydopamine Hydrobromide USDMF includes data on Hydroxydopamine Hydrobromide's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Hydroxydopamine Hydrobromide USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Hydroxydopamine Hydrobromide suppliers with USDMF on PharmaCompass.

Hydroxydopamine Hydrobromide GMP

Hydroxydopamine Hydrobromide Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Hydroxydopamine Hydrobromide GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Hydroxydopamine Hydrobromide GMP manufacturer or Hydroxydopamine Hydrobromide GMP API supplier for your needs.

Hydroxydopamine Hydrobromide CoA

A Hydroxydopamine Hydrobromide CoA (Certificate of Analysis) is a formal document that attests to Hydroxydopamine Hydrobromide's compliance with Hydroxydopamine Hydrobromide specifications and serves as a tool for batch-level quality control.

Hydroxydopamine Hydrobromide CoA mostly includes findings from lab analyses of a specific batch. For each Hydroxydopamine Hydrobromide CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Hydroxydopamine Hydrobromide may be tested according to a variety of international standards, such as European Pharmacopoeia (Hydroxydopamine Hydrobromide EP), Hydroxydopamine Hydrobromide JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Hydroxydopamine Hydrobromide USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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