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Chemistry

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Also known as: Scy-078 citrate, M4nu2sdx3e, Ibrexafungerp citrate [usan], 1965291-08-0, Ibrexafungerp citrate (usan), Brexafemme
Molecular Formula
C50H75N5O11
Molecular Weight
922.2  g/mol
InChI Key
WKIRTJACGBEXBZ-FQGZCCSZSA-N
FDA UNII
M4NU2SDX3E

Ibrexafungerp Citrate
1 2D Structure

Ibrexafungerp Citrate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(1R,5S,6R,7R,10R,11R,14R,15S,20R,21R)-21-[(2R)-2-amino-2,3,3-trimethylbutoxy]-5,7,10,15-tetramethyl-7-[(2R)-3-methylbutan-2-yl]-20-(5-pyridin-4-yl-1,2,4-triazol-1-yl)-17-oxapentacyclo[13.3.3.01,14.02,11.05,10]henicos-2-ene-6-carboxylic acid;2-hydroxypropane-1,2,3-tricarboxylic acid
2.1.2 InChI
InChI=1S/C44H67N5O4.C6H8O7/c1-27(2)28(3)39(7)18-19-41(9)30-12-13-33-40(8)23-52-25-44(33,31(30)14-17-42(41,10)34(39)37(50)51)22-32(35(40)53-24-43(11,45)38(4,5)6)49-36(47-26-48-49)29-15-20-46-21-16-29;7-3(8)1-6(13,5(11)12)2-4(9)10/h14-16,20-21,26-28,30,32-35H,12-13,17-19,22-25,45H2,1-11H3,(H,50,51);13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/t28-,30+,32-,33+,34-,35+,39-,40-,41-,42+,43+,44+;/m1./s1
2.1.3 InChI Key
WKIRTJACGBEXBZ-FQGZCCSZSA-N
2.1.4 Canonical SMILES
CC(C)C(C)C1(CCC2(C3CCC4C5(COCC4(C3=CCC2(C1C(=O)O)C)CC(C5OCC(C)(C(C)(C)C)N)N6C(=NC=N6)C7=CC=NC=C7)C)C)C.C(C(=O)O)C(CC(=O)O)(C(=O)O)O
2.1.5 Isomeric SMILES
C[C@H](C(C)C)[C@]1(CC[C@@]2([C@H]3CC[C@H]4[C@]5(COC[C@]4(C3=CC[C@]2([C@@H]1C(=O)O)C)C[C@H]([C@@H]5OC[C@@](C)(C(C)(C)C)N)N6C(=NC=N6)C7=CC=NC=C7)C)C)C.C(C(=O)O)C(CC(=O)O)(C(=O)O)O
2.2 Other Identifiers
2.2.1 UNII
M4NU2SDX3E
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Brexafemme

2. Ibrexafungerp

3. Mk-3118

4. Scy-078

2.3.2 Depositor-Supplied Synonyms

1. Scy-078 Citrate

2. M4nu2sdx3e

3. Ibrexafungerp Citrate [usan]

4. 1965291-08-0

5. Ibrexafungerp Citrate (usan)

6. Brexafemme

7. Unii-m4nu2sdx3e

8. Chembl4298168

9. Glxc-26020

10. Ibrexafungerp Citrate [who-dd]

11. Ibrexafungerp Citrate [orange Book]

12. D11545

13. (1s,4ar,6as,7r,8r,10ar,10br,12ar,14r,15r)-15-((2r)- 2-amino-2,3,3-trimethylbutoxy)-1,6a,8,10a-tetramethyl-8- ((2r)-3-methylbutan-2-yl)-14-(5-(pyridin-4-yl)-1h-1,2,4- Triazol-1-yl)-1,6,6a,7,8,9,10,10a,10b,11,12,12a-dodecahydro-2h,4h-1,4a-propanophenanthro(1,2-c)pyran-7-carboxylic Acid Compound With 2-hydroxypropane-1,2,3-tricarboxylic Acid (1:1)

14. 4h-1,4a-propano-2h-phenanthro(1,2-c)pyran-7-carboxylic Acid, 15-((2r)-2-amino-2,3,3-trimethylbutoxy)-8-((1r)-1,2-dimethylpropyl)-1,6,6a,7,8,9,10,10a,10b,11,12,12a-dodecahydro-1,6a,8,10a-tetramethyl-14-(5-(4-pyridinyl)-1h-1,2,4-triazol-1-yl)-, (1s,4ar,6as

15. 4h-1,4a-propano-2h-phenanthro(1,2-c)pyran-7-carboxylic Acid, 15-((2r)-2-amino-2,3,3-trimethylbutoxy)-8-((1r)-1,2-dimethylpropyl)-1,6,6a,7,8,9,10,10a,10b,11,12,12a-dodecahydro-1,6a,8,10a-tetramethyl-14-(5-(4-pyridinyl)-1h-1,2,4-triazol-1-yl)-, (1s,4ar,6as,7r,8r,10ar,10br,12ar,14r,15r)-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)

2.4 Create Date
2019-03-24
3 Chemical and Physical Properties
Molecular Weight 922.2 g/mol
Molecular Formula C50H75N5O11
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count15
Rotatable Bond Count14
Exact Mass921.54630823 g/mol
Monoisotopic Mass921.54630823 g/mol
Topological Polar Surface Area258 Ų
Heavy Atom Count66
Formal Charge0
Complexity1650
Isotope Atom Count0
Defined Atom Stereocenter Count12
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antifungal Agents

Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues. (See all compounds classified as Antifungal Agents.)


API Reference Price

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13-Jun-2022
19-Dec-2023
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Looking for 1965291-08-0 / Ibrexafungerp Citrate API manufacturers, exporters & distributors?

Ibrexafungerp Citrate manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Ibrexafungerp Citrate API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Ibrexafungerp Citrate manufacturer or Ibrexafungerp Citrate supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Ibrexafungerp Citrate manufacturer or Ibrexafungerp Citrate supplier.

PharmaCompass also assists you with knowing the Ibrexafungerp Citrate API Price utilized in the formulation of products. Ibrexafungerp Citrate API Price is not always fixed or binding as the Ibrexafungerp Citrate Price is obtained through a variety of data sources. The Ibrexafungerp Citrate Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Ibrexafungerp Citrate

Synonyms

Scy-078 citrate, M4nu2sdx3e, Ibrexafungerp citrate [usan], 1965291-08-0, Ibrexafungerp citrate (usan), Brexafemme

Cas Number

1965291-08-0

Unique Ingredient Identifier (UNII)

M4NU2SDX3E

Ibrexafungerp Citrate Manufacturers

A Ibrexafungerp Citrate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Ibrexafungerp Citrate, including repackagers and relabelers. The FDA regulates Ibrexafungerp Citrate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Ibrexafungerp Citrate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Ibrexafungerp Citrate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Ibrexafungerp Citrate Suppliers

A Ibrexafungerp Citrate supplier is an individual or a company that provides Ibrexafungerp Citrate active pharmaceutical ingredient (API) or Ibrexafungerp Citrate finished formulations upon request. The Ibrexafungerp Citrate suppliers may include Ibrexafungerp Citrate API manufacturers, exporters, distributors and traders.

click here to find a list of Ibrexafungerp Citrate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Ibrexafungerp Citrate WC

A Ibrexafungerp Citrate written confirmation (Ibrexafungerp Citrate WC) is an official document issued by a regulatory agency to a Ibrexafungerp Citrate manufacturer, verifying that the manufacturing facility of a Ibrexafungerp Citrate active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Ibrexafungerp Citrate APIs or Ibrexafungerp Citrate finished pharmaceutical products to another nation, regulatory agencies frequently require a Ibrexafungerp Citrate WC (written confirmation) as part of the regulatory process.

click here to find a list of Ibrexafungerp Citrate suppliers with Written Confirmation (WC) on PharmaCompass.

Ibrexafungerp Citrate GMP

Ibrexafungerp Citrate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Ibrexafungerp Citrate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Ibrexafungerp Citrate GMP manufacturer or Ibrexafungerp Citrate GMP API supplier for your needs.

Ibrexafungerp Citrate CoA

A Ibrexafungerp Citrate CoA (Certificate of Analysis) is a formal document that attests to Ibrexafungerp Citrate's compliance with Ibrexafungerp Citrate specifications and serves as a tool for batch-level quality control.

Ibrexafungerp Citrate CoA mostly includes findings from lab analyses of a specific batch. For each Ibrexafungerp Citrate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Ibrexafungerp Citrate may be tested according to a variety of international standards, such as European Pharmacopoeia (Ibrexafungerp Citrate EP), Ibrexafungerp Citrate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Ibrexafungerp Citrate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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