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Ibuprofen Lysinate

Ibuprofen Lysinate

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Valsynthese, part of the SSE Group, is a CDMO focused on highly energetic and highly hazardous chemistry.

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Bloomage is a one-stop source for CEP Sodium Hyaluronate and Hyaluronic Acid// FDA-inspected & GMP-certified.

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CHEMISTRY
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ACTIVE PHARMA INGREDIENTS

6 API Suppliers, 2 USDMF, 3 EU WC, 1 NDC API, 5 Listed Suppliers, $ API Reference Price

6 API Suppliers
2 USDMF
3 EU WC
1 NDC API
5 Listed Suppliers
$ API Reference Price

FINISHED DOSAGE FORMULATIONS

19 FDF Dossiers, 2 FDA Orange Book, 8 Europe, 9 Listed Dossiers

19 FDF Dossiers
2 FDA Orange Book
8 Europe
9 Listed Dossiers

DIGITAL CONTENT

4 NEWS #PharmaBuzz

media
4 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

6 Finished Drug Prices

globalSalesInformation
6 Finished Drug Prices

MARKET PLACE

3 APIs

marketPlace
3 APIs

PATENTS & EXCLUSIVITIES

1 US Patents

patents
1 US Patents

ANALYTICAL

1 BioAnalytical Methods

otherMethods
1 BioAnalytical Methods

IOL Ibuprofen Lysinate

Synopsis

ACTIVE PHARMA INGREDIENTS

6

API Suppliers

2

USDMF

0

CEP/COS

CEP/COS Certifications

0

JDMF

3

EU WC

0

KDMF

1

NDC API

0

VMF

5

Listed Suppliers

API REF. PRICE (USD/KG)

$

$ 40

MARKET PLACE

3

API

0

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

19

FDF Dossiers

2

FDA Orange Book

FDA (Orange Book)

8

Europe

0

Canada

0

Australia

0

South Africa

9

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

0

EDQM

0

USP

0

JP

0

Others

PATENTS & EXCLUSIVITIES

1

US Patents

0

US Exclusivities

0

Health Canada Patents

DIGITAL CONTENT

0

Data Compilation #PharmaFlow

0

Stock Recap #PipelineProspector

0

Weekly News Recap #Phispers

4

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

NA

Annual Reports (USD Million)

NA

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: Ibuprofen lysine, 57469-76-8, Ibuprofen dl-lysine, Ibuprofen d,l-lysinate, 079x7dl13m, (rs)-2-(4-(2-methylpropyl)phenyl)propanoic acid d,l-lysine salt

Molecular Formula

C₁₉H₃₂N₂O₄

Molecular Weight

352.5 g/mol

InChI Key

IHHXIUAEPKVVII-UHFFFAOYSA-N

FDA UNII

079X7DL13M

Ibuprofen Lysinate

1 2D Structure

Ibuprofen Lysinate

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

2,6-diaminohexanoic acid;2-[4-(2-methylpropyl)phenyl]propanoic acid

2.1.2 InChI

InChI=1S/C13H18O2.C6H14N2O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15;7-4-2-1-3-5(8)6(9)10/h4-7,9-10H,8H2,1-3H3,(H,14,15);5H,1-4,7-8H2,(H,9,10)

2.1.3 InChI Key

IHHXIUAEPKVVII-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CC(C)CC1=CC=C(C=C1)C(C)C(=O)O.C(CCN)CC(C(=O)O)N

2.2 Other Identifiers

2.2.1 UNII

079X7DL13M

2.3 Synonyms

2.3.1 Depositor-Supplied Synonyms

1. Ibuprofen Lysine

2. 57469-76-8

3. Ibuprofen Dl-lysine

4. Ibuprofen D,l-lysinate

5. 079x7dl13m

6. (rs)-2-(4-(2-methylpropyl)phenyl)propanoic Acid D,l-lysine Salt

7. 2,6-diaminohexanoic Acid Compound With 2-(4-isobutylphenyl)propanoic Acid (1:1)

8. (rs)-2-[4-(2-methylpropyl)phenyl]propanoic Acid D,l-lysine Salt

9. (2s)-2,6-diaminohexanoic Acid;2-[4-(2-methylpropyl)phenyl]propanoic Acid

10. Neoprofen;ibuprofen-lys

11. Starbld0004237

12. Schembl44616

13. Unii-079x7dl13m

14. Dtxsid50432054

15. Bcp27681

16. Akos015963349

17. Ac-19865

18. Ac-32764

19. Ft-0670261

20. Ft-0670262

21. Lysine, Mono(alpha-methyl-4-(2-methylpropyl)benzeneacetate)

22. Dl-lysine, Mono(alpha-methyl-4-(2-methylpropyl)benzeneacetate)

23. Lysine, Alpha-methyl-4-(2-methylpropyl)benzeneacetate (1:1)

24. Dl-lysine, Mono(.alpha.-methyl-4-(2-methylpropyl)benzeneacetate)

25. Lysine, .alpha.-methyl-4-(2-methylpropyl)benzeneacetate (1:1)

26. Lysine, Mono(.alpha.-methyl-4-(2-methylpropyl)benzeneacetate)

27. Benzeneacetic Acid, .alpha.-methyl-4-(2-methylpropyl)-, Compd. With Lysine (1:1)

28. Benzeneacetic Acid, Alpha-methyl-4-(2-methylpropyl)-, Compd. With Lysine (1:1)

2.4 Create Date

2006-10-25

3 Chemical and Physical Properties

Molecular Formula	C₁₉H₃₂N₂O₄
Molecular Weight	352.5 g/mol
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	9
Exact Mass	352.23620751 g/mol
Monoisotopic Mass	352.23620751 g/mol
Topological Polar Surface Area	127 Å²
Heavy Atom Count	25
Formal Charge	0
Complexity	309
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	2
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Pharmacology and Biochemistry

4.1 FDA Pharmacological Classification

4.1.1 Pharmacological Classes

Cyclooxygenase Inhibitors [MoA]; Nonsteroidal Anti-inflammatory Drug [EPC]; Anti-Inflammatory Agents, Non-Steroidal [CS]

API SUPPLIERS

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USDMF

01

Dipharma Francis Srl

Italy

Antibody Engineering

Not Confirmed

02

Solara Active Pharma Sciences Ltd

India

Antibody Engineering

Not Confirmed

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EU WC

01

IOL Chemicals and Pharmaceuticals

India

Antibody Engineering

Not Confirmed

IOL Chemicals is an innovation-driven bulk drug, Intermediate and Specialty Chemicals company.

Contact Supplier

Contact Supplier

India

Digital Content

Ibuprofen Lysinate IH

Date of Issue : 2022-03-24

Valid Till : 2025-03-17

Written Confirmation Number : WC-0004

Address of the Firm : Village Fatehgarh Chana, Mansa Road, Barnala, Punjab

Product Web Link

Digital Content

02

Solara Active Pharma Sciences

India

Antibody Engineering

Not Confirmed

03

Solara Active Pharma Sciences

India

Antibody Engineering

Not Confirmed

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NDC API

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Listed Suppliers

01

IOL Chemicals and Pharmaceuticals

India

Medlab Asia & Asia Health

Not Confirmed

IOL Chemicals is an innovation-driven bulk drug, Intermediate and Specialty Chemicals company.

Contact Supplier

Contact Supplier

India

Digital Content

Ibuprofen Lysinate

About the Company : With a history spanning over three decades, IOL Chemicals and Pharmaceuticals Limited is an innovation-driven company that specializes in bulk drugs, intermediates and specialty ch...

With a history spanning over three decades, IOL Chemicals and Pharmaceuticals Limited is an innovation-driven company that specializes in bulk drugs, intermediates and specialty chemicals. As an API-based company, IOL Chemicals has substantial manufacturing capacities that provide economies of scale and cost advantages. It also has extensive expertise in specialty chemicals. IOL Chemicals’ API portfolio includes various therapeutic categories such as pain management, anti-diabetic, anti-hypertensive and anti-convulsant. IOL Chemicals is a backward-integrated company that produces all intermediates and key starting materials for ibuprofen.

Product Web Link

Digital Content

02

BASF

Germany

Medlab Asia & Asia Health

Not Confirmed

03

Dipharma

Italy

Medlab Asia & Asia Health

Not Confirmed

04

Olon S.p.A

Italy

Medlab Asia & Asia Health

Not Confirmed

05

Solara Active Pharma Sciences

India

Medlab Asia & Asia Health

Not Confirmed

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API Reference Price

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NO. 1544869 DT. 05.06.2023)","address":"NO.201, DEVAVRATA SECTOR 17,,VASHI","city":"NAVI MUMBAI,MAHARASHTRA","supplier":"ALKALOID AD SKOPJE","supplierCountry":"INDIA","foreign_port":"THESSALONIKI","customer":"SOLARA ACTIVE PHARMA SCIENCES","customerCountry":"INDIA","quantity":"400.00","actualQuantity":"400","unit":"KGS","unitRateFc":"42","totalValueFC":"17310.2","currency":"USD","unitRateINR":"3636.3","date":"15-Oct-2024","totalValueINR":"1454516.49","totalValueInUsd":"17310.2","indian_port":"Madras Sea","hs_no":"29420090","bill_no":"6141177","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"THESSALONIKI","supplierAddress":"BLVD, ALEKSANDAR MAKEDONSKI 12.1000 SKOPJE, SDNF MACEDONIA,THE FORMER YUGO","customerAddress":"NO.201, DEVAVRATA SECTOR 17,,VASHI"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1728930600,"product":"IBUPROFEN LYSINE(REIMPORT CARGO- EXPORTED VIDE SB. NO. 7094680 DT. 29.01.2024)","address":"NO.201, DEVAVRATA SECTOR 17,,VASHI","city":"NAVI MUMBAI,MAHARASHTRA","supplier":"ALKALOID AD SKOPJE","supplierCountry":"INDIA","foreign_port":"THESSALONIKI","customer":"SOLARA ACTIVE PHARMA SCIENCES","customerCountry":"INDIA","quantity":"1500.00","actualQuantity":"1500","unit":"KGS","unitRateFc":"40","totalValueFC":"61993.9","currency":"USD","unitRateINR":"3472.8","date":"15-Oct-2024","totalValueINR":"5209130.13","totalValueInUsd":"61993.9","indian_port":"Madras Sea","hs_no":"29420090","bill_no":"6141146","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"THESSALONIKI","supplierAddress":"BLVD, ALEKSANDAR MAKEDONSKI 12.1000 SKOPJE, SDNF MACEDONIA,THE FORMER YUGO","customerAddress":"NO.201, DEVAVRATA SECTOR 17,,VASHI"}]

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country	Total Quantity (KGS)	Average Price (USD/KGS)	Number of Transactions

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