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    Also known as: 31121-93-4, Ibuprofen sodium salt, Sodium ibuprofen, Sodium 2-(4-isobutylphenyl)propionate, Sodium 2-[4-(2-methylpropyl)phenyl]propanoate, Ibuprofen sodium anhydrous
    Molecular Formula
    C13H17NaO2
    Molecular Weight
    228.26  g/mol
    InChI Key
    PTTPUWGBPLLBKW-UHFFFAOYSA-M
    FDA UNII
    O0PJ4UZ01U
    Ibuprofen Sodium
    Ibuprofen Sodium is the sodium salt form of ibuprofen, a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic activities. Upon administration, ibuprofen inhibits the activity of cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. This leads to decreased prostaglandin synthesis, by prostaglandin synthase, the main physiologic effect of ibuprofen. Ibuprofen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation.
    1 2D Structure

    Ibuprofen Sodium

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    sodium;2-[4-(2-methylpropyl)phenyl]propanoate
    2.1.2 InChI
    InChI=1S/C13H18O2.Na/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15;/h4-7,9-10H,8H2,1-3H3,(H,14,15);/q;+1/p-1
    2.1.3 InChI Key
    PTTPUWGBPLLBKW-UHFFFAOYSA-M
    2.1.4 Canonical SMILES
    CC(C)CC1=CC=C(C=C1)C(C)C(=O)[O-].[Na+]
    2.2 Other Identifiers
    2.2.1 UNII
    O0PJ4UZ01U
    2.3 Synonyms
    2.3.1 Depositor-Supplied Synonyms

    1. 31121-93-4

    2. Ibuprofen Sodium Salt

    3. Sodium Ibuprofen

    4. Sodium 2-(4-isobutylphenyl)propionate

    5. Sodium 2-[4-(2-methylpropyl)phenyl]propanoate

    6. Ibuprofen Sodium Anhydrous

    7. P-isobutylhydratropic Acid Sodium Salt

    8. Sodium 2-(4-isobutylphenyl)propanoate

    9. Ibuprofen (sodium)

    10. Sodium;2-[4-(2-methylpropyl)phenyl]propanoate

    11. O0pj4uz01u

    12. Ibuprofensodiumsalt

    13. Einecs 250-477-6

    14. Unii-o0pj4uz01u

    15. Esprenit (tn)

    16. Sodium Ibuprofen Salt

    17. Hydratropic Acid, P-isobutyl-, Sodium Salt

    18. Benzeneacetic Acid, Alpha-methyl-4-(2-methylpropyl)-, Sodium Salt

    19. Schembl139269

    20. Chembl1241153

    21. Dtxsid4040501

    22. Smsf0005424

    23. Hy-78131c

    24. Sodium2-(4-isobutylphenyl)propanoate

    25. Akos015994627

    26. Cb08098

    27. Hs-0087

    28. Sodium 2-(4'-isobutylphenyl)propionate

    29. 5264-06-2

    30. Bim-0005680.p001

    31. Cs-0031024

    32. 2-(p-isobutylphenyl)propionic Acid Sodium Salt

    33. D08059

    34. ((c)i)-ibuprofen-d3, Sodium Salt (

    35. A-methyl-d3)

    36. W-110791

    37. Q27285172

    38. Benzeneacetic Acid, .alpha.-methyl-4-(2-methylpropyl)-, Sodium Salt (1:1)

    39. Benzeneacetic Acid, .alpha.-methyl-4-(2-methylpropyl)-,sodium Salt

    2.4 Create Date
    2006-02-02
    3 Chemical and Physical Properties
    Molecular Weight 228.26 g/mol
    Molecular Formula C13H17NaO2
    Hydrogen Bond Donor Count0
    Hydrogen Bond Acceptor Count2
    Rotatable Bond Count4
    Exact Mass228.11262406 g/mol
    Monoisotopic Mass228.11262406 g/mol
    Topological Polar Surface Area40.1 Ų
    Heavy Atom Count16
    Formal Charge0
    Complexity208
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count1
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Pharmacology and Biochemistry
    4.1 FDA Pharmacological Classification
    4.1.1 Pharmacological Classes
    Cyclooxygenase Inhibitors [MoA]; Nonsteroidal Anti-inflammatory Drug [EPC]; Anti-Inflammatory Agents, Non-Steroidal [CS]

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    30-Jan-2021
    29-Oct-2024
    KGS
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    Average Price (USD/KGS)

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    Total Quantity (KGS)

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    Quantity (KGS) & Unit rate (USD/KGS) over time

    API Imports and Exports

    Importing Country Total Quantity
    (KGS)    		 Average Price
    (USD/KGS)    		 Number of Transactions

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    ABOUT THIS PAGE

    Ibuprofen Sodium Manufacturers

    A Ibuprofen Sodium manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Ibuprofen Sodium, including repackagers and relabelers. The FDA regulates Ibuprofen Sodium manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Ibuprofen Sodium API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Ibuprofen Sodium manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Ibuprofen Sodium Suppliers

    A Ibuprofen Sodium supplier is an individual or a company that provides Ibuprofen Sodium active pharmaceutical ingredient (API) or Ibuprofen Sodium finished formulations upon request. The Ibuprofen Sodium suppliers may include Ibuprofen Sodium API manufacturers, exporters, distributors and traders.

    click here to find a list of Ibuprofen Sodium suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Ibuprofen Sodium USDMF

    A Ibuprofen Sodium DMF (Drug Master File) is a document detailing the whole manufacturing process of Ibuprofen Sodium active pharmaceutical ingredient (API) in detail. Different forms of Ibuprofen Sodium DMFs exist exist since differing nations have different regulations, such as Ibuprofen Sodium USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Ibuprofen Sodium DMF submitted to regulatory agencies in the US is known as a USDMF. Ibuprofen Sodium USDMF includes data on Ibuprofen Sodium's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Ibuprofen Sodium USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Ibuprofen Sodium suppliers with USDMF on PharmaCompass.

    Ibuprofen Sodium KDMF

    In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

    Pharmaceutical companies submit a Ibuprofen Sodium Drug Master File in Korea (Ibuprofen Sodium KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Ibuprofen Sodium. The MFDS reviews the Ibuprofen Sodium KDMF as part of the drug registration process and uses the information provided in the Ibuprofen Sodium KDMF to evaluate the safety and efficacy of the drug.

    After submitting a Ibuprofen Sodium KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Ibuprofen Sodium API can apply through the Korea Drug Master File (KDMF).

    click here to find a list of Ibuprofen Sodium suppliers with KDMF on PharmaCompass.

    Ibuprofen Sodium WC

    A Ibuprofen Sodium written confirmation (Ibuprofen Sodium WC) is an official document issued by a regulatory agency to a Ibuprofen Sodium manufacturer, verifying that the manufacturing facility of a Ibuprofen Sodium active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Ibuprofen Sodium APIs or Ibuprofen Sodium finished pharmaceutical products to another nation, regulatory agencies frequently require a Ibuprofen Sodium WC (written confirmation) as part of the regulatory process.

    click here to find a list of Ibuprofen Sodium suppliers with Written Confirmation (WC) on PharmaCompass.

    Ibuprofen Sodium NDC

    National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Ibuprofen Sodium as an active pharmaceutical ingredient (API).

    Finished drug products

    The FDA updates the NDC directory daily. The NDC numbers for Ibuprofen Sodium API and other APIs are published in this directory by the FDA.

    Unfinished drugs

    The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

    Pharmaceutical companies that manufacture Ibuprofen Sodium as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

    Compounded drug products

    The NDC directory also contains data on finished compounded human drug products that contain Ibuprofen Sodium and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Ibuprofen Sodium NDC to their finished compounded human drug products, they may choose to do so.

    click here to find a list of Ibuprofen Sodium suppliers with NDC on PharmaCompass.

    Ibuprofen Sodium GMP

    Ibuprofen Sodium Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Ibuprofen Sodium GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Ibuprofen Sodium GMP manufacturer or Ibuprofen Sodium GMP API supplier for your needs.

    Ibuprofen Sodium CoA

    A Ibuprofen Sodium CoA (Certificate of Analysis) is a formal document that attests to Ibuprofen Sodium's compliance with Ibuprofen Sodium specifications and serves as a tool for batch-level quality control.

    Ibuprofen Sodium CoA mostly includes findings from lab analyses of a specific batch. For each Ibuprofen Sodium CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Ibuprofen Sodium may be tested according to a variety of international standards, such as European Pharmacopoeia (Ibuprofen Sodium EP), Ibuprofen Sodium JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Ibuprofen Sodium USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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