Find Idarubicin Hydrochloride manufacturers, exporters & distributors on PharmaCompass

Idarubicin Hydrochloride

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

15 API Suppliers, 7 USDMF, 3 KDMF, 4 NDC API, 9 Listed Suppliers, $ API Reference Price

15 API Suppliers
7 USDMF
3 KDMF
4 NDC API
9 Listed Suppliers
$ API Reference Price

DEVELOPMENTS

1 Drugs in Development

1 Drugs in Development

FINISHED DOSAGE FORMULATIONS

50 FDF Dossiers, 13 FDA Orange Book, 22 Europe, 1 Canada, 2 Australia, 3 South Africa, 9 Listed Dossiers

50 FDF Dossiers
13 FDA Orange Book
22 Europe
1 Canada
2 Australia
3 South Africa
9 Listed Dossiers

RELATED EXCIPIENT COMPANIES

3 Actylis, 1 Kerry, 1 Pluviaendo

relatedExcipients
3 Actylis
1 Kerry
1 Pluviaendo

EXCIPIENTS BY APPLICATIONS

4 Parenteral, 1 Controlled & Modified Release, 1 Film Formers & Plasticizers, 1 Coating Systems & Additives, 1 Topical

excipientsByApplications
4 Parenteral
1 Controlled & Modified Release
1 Film Formers & Plasticizers
1 Coating Systems & Additives
1 Topical

DIGITAL CONTENT

7 NEWS #PharmaBuzz

media
7 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

17 Finished Drug Prices

globalSalesInformation
17 Finished Drug Prices

MARKET PLACE

1 APIs, 2 FDF Dossiers

marketPlace
1 APIs
2 FDF Dossiers

PATENTS & EXCLUSIVITIES

1 Health Canada Patents

patents
1 Health Canada Patents

REF. STANDARDS & IMPURITIES

1 USP , 1 Others

otherSolutions
1 USP
1 Others

Transo Pharm Handels GmbH

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

8EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: Idarubicin hcl, 57852-57-0, Idamycin, Zavedos, Idarubicin (hydrochloride), 4-demethoxydaunorubicin

Molecular Formula

C₂₆H₂₈ClNO₉

Molecular Weight

534.0 g/mol

InChI Key

JVHPTYWUBOQMBP-RVFAQHLVSA-N

FDA UNII

5VV3MDU5IE

An orally administered anthracycline antineoplastic. The compound has shown activity against BREAST NEOPLASMS; LYMPHOMA; and LEUKEMIA.

1 2D Structure

Idarubicin Hydrochloride

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride

2.1.2 InChI

InChI=1S/C26H27NO9.ClH/c1-10-21(29)15(27)7-17(35-10)36-16-9-26(34,11(2)28)8-14-18(16)25(33)20-19(24(14)32)22(30)12-5-3-4-6-13(12)23(20)31;/h3-6,10,15-17,21,29,32-34H,7-9,27H2,1-2H3;1H/t10-,15-,16-,17-,21+,26-;/m0./s1

2.1.3 InChI Key

JVHPTYWUBOQMBP-RVFAQHLVSA-N

2.1.4 Canonical SMILES

CC1C(C(CC(O1)OC2CC(CC3=C2C(=C4C(=C3O)C(=O)C5=CC=CC=C5C4=O)O)(C(=O)C)O)N)O.Cl

2.1.5 Isomeric SMILES

C[C@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](CC3=C2C(=C4C(=C3O)C(=O)C5=CC=CC=C5C4=O)O)(C(=O)C)O)N)O.Cl

2.2 Other Identifiers

2.2.1 UNII

5VV3MDU5IE

2.3 Synonyms

2.3.1 MeSH Synonyms

1. 4 Demethoxydaunorubicin

2. 4 Desmethoxydaunorubicin

3. 4-demethoxydaunorubicin

4. 4-desmethoxydaunorubicin

5. Hydrochloride, Idarubicin

6. Idarubicin

7. Imi 30

8. Imi-30

9. Imi30

10. Nsc 256439

11. Nsc-256439

12. Nsc256439

2.3.2 Depositor-Supplied Synonyms

1. Idarubicin Hcl

2. 57852-57-0

3. Idamycin

4. Zavedos

5. Idarubicin (hydrochloride)

6. 4-demethoxydaunorubicin

7. Imi 30

8. Imi-30

9. 5vv3mdu5ie

10. Idarubicinhydrochloride

11. Cpd000466355

12. 4-demethoxydaunorubicin Hydrochloride

13. Mls001401448

14. Nsc-256439

15. Dsstox_cid_27775

16. Dsstox_rid_82550

17. Dsstox_gsid_47797

18. Smr000466355

19. Idamycin Pfs

20. Cas-57852-57-0

21. Nsc 256439

22. Ncgc00093976-03

23. Unii-5vv3mdu5ie

24. Idarubicin Hydrochloride Pfs

25. Sr-01000075934

26. Idamycin (tn)

27. Einecs 260-990-7

28. Idarubicin Hydrochlorid

29. Idarubicin Hydrochloride [usan:usp:inn]

30. Schembl4838

31. Mls000759470

32. Chembl1200976

33. Dtxsid0047797

34. Chebi:31686

35. Kuc110342c

36. Ex-a1148

37. Tox21_111236

38. Idarubicin Hydrochloride [mi]

39. Mfcd00897212

40. S1228

41. Idarubicin Hydrochloride (jp17/usp)

42. Idarubicin Hydrochloride [jan]

43. Akos025402118

44. Tox21_111236_1

45. Ac-5255

46. Ccg-100886

47. Cs-1061

48. Idarubicin Hydrochloride [usan]

49. Nc00136

50. Daunomycin, 4-demethoxy-, Hydrochloride

51. Idarubicin Hydrochloride [mart.]

52. Idarubicin Hydrochloride [vandf]

53. Idarubicin Hydrochloride [usp-rs]

54. Idarubicin Hydrochloride [who-dd]

55. Ncgc00093976-08

56. (1s,3s)-3-acetyl-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-6,11-dioxo-1-naphthacenyl 3-amino-2,3,6-trideoxy-alpha-l-lyxo-hexopyranoside, Hydrochloride

57. As-75944

58. Hy-17381

59. Ksc-230-185-1

60. Idarubicin Hydrochloride [orange Book]

61. D01747

62. Idarubicin Hydrochloride [usp Monograph]

63. 852i570

64. Q-101407

65. Sr-01000075934-5

66. 4-demethoxydaunorubicin (nsc256439, 4-dmdr) Hcl

67. Q27262943

68. (7s,9s)-9-acetyl-7-(((2r,4s,5s,6s)-4-amino-5-hydroxy-6-methyltetrahydro-2h-pyran-2-yl)oxy)-6,9,11-trihydroxy-7,8,9,10-tetrahydrotetracene-5,12-dione Hydrochloride

69. (7s,9s)-9-acetyl-7-(((2r,4s,5s,6s)-4-amino-5-hydroxy-6-methyltetrahydro-2h-pyran-2-yl)oxy)-6,9,11-trihydroxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride

70. (7s,9s)-9-acetyl-7-((2r,4s,5s,6s)-4-amino-5-hydroxy-6-methyltetrahydro-2h-pyran-2-yloxy)-6,9,11-trihydroxy-7,8,9,10-tetrahydrotetracene-5,12-dione Hydrochloride

71. (7s-cis)-9-acetyl-7-((3-amino-2,3,6-trideoxy-alpha-l-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,9,11-trihydroxynaphthacene-5,12-dione Hydrochloride

72. 1s,3s)-3-acetyl-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-6,11-dioxo-1-naphthacenyl 3-amino-2,3,6-trideoxy-.alpha.-l-lyxo-hexopyranoside, Hydrochloride

73. 5,12-naphthacenedione, 9-acetyl-7-((3-amino-2,3,6-trideoxy-.alpha.-l-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,9,11-trihydroxyhydrochloride, (7s-cis)-

74. 5,12-naphthacenedione, 9-acetyl-7-((3-amino-2,3,6-trideoxy-alpha-l-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,9,11-trihydroxyhydrochloride, (7s-cis)-

2.4 Create Date

2005-06-24

3 Chemical and Physical Properties

Molecular Formula	C₂₆H₂₈ClNO₉
Molecular Weight	534.0 g/mol
Hydrogen Bond Donor Count	6
Hydrogen Bond Acceptor Count	10
Rotatable Bond Count	3
Exact Mass	533.1452592 g/mol
Monoisotopic Mass	533.1452592 g/mol
Topological Polar Surface Area	177 Å²
Heavy Atom Count	37
Formal Charge	0
Complexity	912
Isotope Atom Count	0
Defined Atom Stereocenter Count	6
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Drug and Medication Information

4.1 Drug Information

1 of 2
Drug Name	Idarubicin hydrochloride
Drug Label	IDAMYCIN PFS Injection contains idarubicin hydrochloride and is a sterile, semi-synthetic, preservative-free solution (PFS) antineoplastic anthracycline for intravenous use. Chemically, idarubicin hydrochloride is 5, 12- Naphthacenedione, 9-acetyl-7-...
Active Ingredient	Idarubicin hydrochloride
Dosage Form	Injectable
Route	Injection
Strength	1mg/ml
Market Status	Prescription
Company	Sandoz; Fresenius Kabi Usa; Onco Therapies; Eurohlth Intl

2 of 2
Drug Name	Idarubicin hydrochloride
Drug Label	IDAMYCIN PFS Injection contains idarubicin hydrochloride and is a sterile, semi-synthetic, preservative-free solution (PFS) antineoplastic anthracycline for intravenous use. Chemically, idarubicin hydrochloride is 5, 12- Naphthacenedione, 9-acetyl-7-...
Active Ingredient	Idarubicin hydrochloride
Dosage Form	Injectable
Route	Injection
Strength	1mg/ml
Market Status	Prescription
Company	Sandoz; Fresenius Kabi Usa; Onco Therapies; Eurohlth Intl

5 Pharmacology and Biochemistry

5.1 MeSH Pharmacological Classification

Topoisomerase II Inhibitors

Compounds that inhibit the activity of DNA TOPOISOMERASE II. Included in this category are a variety of ANTINEOPLASTIC AGENTS which target the eukaryotic form of topoisomerase II and ANTIBACTERIAL AGENTS which target the prokaryotic form of topoisomerase II. (See all compounds classified as Topoisomerase II Inhibitors.)

Antibiotics, Antineoplastic

Chemical substances, produced by microorganisms, inhibiting or preventing the proliferation of neoplasms. (See all compounds classified as Antibiotics, Antineoplastic.)

5.2 FDA Pharmacological Classification

5.2.1 Pharmacological Classes

Anthracyclines [CS]; Topoisomerase Inhibitors [MoA]; Anthracycline Topoisomerase Inhibitor [EPC]

API SUPPLIERS

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

USDMF

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

KDMF

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

NDC API

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

Listed Suppliers

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

API Reference Price

[{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q3","strtotime":1662402600,"product":"IDARUBICIN HYDROCHLORIDE","address":"VILLAGE NAG KALAN,MAJITHA ROAD,MAJ ITHA","city":"AMRITSAR,PUNJAB","supplier":"QUANZHOU FORTUNE TRADE ","supplierCountry":"CHINA","foreign_port":"NA","customer":"KWALITY PHARMACEUTICALS","customerCountry":"INDIA","quantity":"0.01","actualQuantity":"11","unit":"GMS","unitRateFc":"1300","totalValueFC":"14355.1","currency":"USD","unitRateINR":"104585","date":"06-Sep-2022","totalValueINR":"1150435","totalValueInUsd":"14355.1","indian_port":"DELHI AIR","hs_no":"29339990","bill_no":"2318974","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"VILLAGE NAG KALAN,MAJITHA ROAD,MAJ ITHA"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1682447400,"product":"IDARUBICIN HYDROCHLORIDE (THIRD COUNTRY EXPORT)","address":"A-2,419, CELEBRATION CITY CENTER,, GALA GYM ROAD,SOUTH BOPAL,BOPAL","city":"AHMEDABAD,GUJARAT","supplier":"ZHEJIANG HISUN PHARMACEUTICAL","supplierCountry":"CHINA","foreign_port":"NA","customer":"APRAMEYA PHARMACHEM PVT LTD","customerCountry":"INDIA","quantity":"0.05","actualQuantity":"50","unit":"GMS","unitRateFc":"1800","totalValueFC":"91313.7","currency":"USD","unitRateINR":"149670","date":"26-Apr-2023","totalValueINR":"7483500","totalValueInUsd":"91313.7","indian_port":"BOMBAY AIR","hs_no":"29419090","bill_no":"5689058","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"A-2,419, CELEBRATION CITY CENTER,, GALA GYM ROAD,SOUTH BOPAL,BOPAL"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1710959400,"product":"IDARUBICIN HYDROCHLORIDE (QTY:1 X 0.5 G, VALUE: USD 251.02)(FOC)","address":"P.NO. D6 D8, SY.NO. 234\/2,234\/3,","city":"TURKAPALLY(V),SHAMEERPET, HYDERABAD","supplier":"UNITED STATES PHARMACOPEIAL ","supplierCountry":"UNITED KINGDOM","foreign_port":"WASHINGTON, DULLES I","customer":"UNITED STATES PHARMACOPEIA - INDIA PRIVATE LIMITED","customerCountry":"INDIA","quantity":"0.00","actualQuantity":"0.0005","unit":"KGS","unitRateFc":"502040","totalValueFC":"259.5","currency":"USD","unitRateINR":"43090920","date":"21-Mar-2024","totalValueINR":"21545.46","totalValueInUsd":"259.5","indian_port":"Hyderabad Air","hs_no":"29419090","bill_no":"2679542","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED KINGDOM","selfForZScoreResived":"Pharma Grade","supplierPort":"WASHINGTON, DULLES I","supplierAddress":"7135 ENGLISH MUFFIN WAY FREDERICK,MD, US 21704, UNITED STATES OF AMERICA United States","customerAddress":"P.NO. D6 D8, SY.NO. 234\/2,234\/3,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1710959400,"product":"IDARUBICIN HYDROCHLORIDE (QTY:1 X 50 MG, VALUE: USD 812) (FOC)","address":"P.NO. D6 D8, SY.NO. 234\/2,234\/3,","city":"TURKAPALLY(V),SHAMEERPET, HYDERABAD","supplier":"UNITED STATES PHARMACOPEIAL ","supplierCountry":"UNITED KINGDOM","foreign_port":"WASHINGTON, DULLES I","customer":"UNITED STATES PHARMACOPEIA - INDIA PRIVATE LIMITED","customerCountry":"INDIA","quantity":"0.00","actualQuantity":"0.00005","unit":"KGS","unitRateFc":"16240000","totalValueFC":"839.3","currency":"USD","unitRateINR":"1393906000","date":"21-Mar-2024","totalValueINR":"69695.3","totalValueInUsd":"839.3","indian_port":"Hyderabad Air","hs_no":"29419090","bill_no":"2679542","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED KINGDOM","selfForZScoreResived":"Pharma Grade","supplierPort":"WASHINGTON, DULLES I","supplierAddress":"7135 ENGLISH MUFFIN WAY FREDERICK,MD, US 21704, UNITED STATES OF AMERICA United States","customerAddress":"P.NO. D6 D8, SY.NO. 234\/2,234\/3,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1710959400,"product":"IDARUBICIN HYDROCHLORIDE (QTY:2 X 0.4 G, VALUE: USD 203.42\/EACH) (FOC)","address":"P.NO. D6 D8, SY.NO. 234\/2,234\/3,","city":"TURKAPALLY(V),SHAMEERPET, HYDERABAD","supplier":"UNITED STATES PHARMACOPEIAL ","supplierCountry":"UNITED KINGDOM","foreign_port":"WASHINGTON, DULLES I","customer":"UNITED STATES PHARMACOPEIA - INDIA PRIVATE LIMITED","customerCountry":"INDIA","quantity":"0.00","actualQuantity":"0.0008","unit":"KGS","unitRateFc":"508550","totalValueFC":"420.5","currency":"USD","unitRateINR":"43649687.5","date":"21-Mar-2024","totalValueINR":"34919.75","totalValueInUsd":"420.5","indian_port":"Hyderabad Air","hs_no":"29419090","bill_no":"2679542","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED KINGDOM","selfForZScoreResived":"Pharma Grade","supplierPort":"WASHINGTON, DULLES I","supplierAddress":"7135 ENGLISH MUFFIN WAY FREDERICK,MD, US 21704, UNITED STATES OF AMERICA United States","customerAddress":"P.NO. D6 D8, SY.NO. 234\/2,234\/3,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1710959400,"product":"IDARUBICIN HYDROCHLORIDE (QTY:2 X 50 MG, VALUE: USD 812\/EACH) (FOC)","address":"P.NO. D6 D8, SY.NO. 234\/2,234\/3,","city":"TURKAPALLY(V),SHAMEERPET, HYDERABAD","supplier":"UNITED STATES PHARMACOPEIAL ","supplierCountry":"UNITED KINGDOM","foreign_port":"WASHINGTON, DULLES I","customer":"UNITED STATES PHARMACOPEIA - INDIA PRIVATE LIMITED","customerCountry":"INDIA","quantity":"0.00","actualQuantity":"0.0001","unit":"KGS","unitRateFc":"16240000","totalValueFC":"1678.7","currency":"USD","unitRateINR":"1393906100","date":"21-Mar-2024","totalValueINR":"139390.61","totalValueInUsd":"1678.7","indian_port":"Hyderabad Air","hs_no":"29419090","bill_no":"2679542","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED KINGDOM","selfForZScoreResived":"Pharma Grade","supplierPort":"WASHINGTON, DULLES I","supplierAddress":"7135 ENGLISH MUFFIN WAY FREDERICK,MD, US 21704, UNITED STATES OF AMERICA United States","customerAddress":"P.NO. D6 D8, SY.NO. 234\/2,234\/3,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1723055400,"product":"IDARUBICIN HYDROCHLORIDE (HCL)","address":"VILLAGE NAG KALAN,MAJITHA ROAD,MAJ","city":"AMRITSAR,PUNJAB","supplier":"M\/S. WUHAN HANWEISHI PHARMCHEM CO LTD","supplierCountry":"CHINA","foreign_port":"HONG KONG","customer":"KWALITY PHARMACEUTICALS","customerCountry":"INDIA","quantity":"0.01","actualQuantity":"10","unit":"GMS","unitRateFc":"1250","totalValueFC":"12607.5","currency":"USD","unitRateINR":"105750","date":"08-Aug-2024","totalValueINR":"1057500","totalValueInUsd":"12607.5","indian_port":"Delhi Air","hs_no":"29339990","bill_no":"4945133","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"HONG KONG","supplierAddress":"ADD: RM1401 GAOXIONG TOWER #88GAOXIONG ROAD JIANGAN DISTRICTWUHAN CHINA SDNF","customerAddress":"VILLAGE NAG KALAN,MAJITHA ROAD,MAJ"}]