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Chemistry

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Also known as: 79944-56-2, Idazoxan (hydrochloride), Idazoxan hcl, Rx 781094, (+/-)-idazoxan monohydrochloride, Mls000069708
Molecular Formula
C11H13ClN2O2
Molecular Weight
240.68  g/mol
InChI Key
MYUBYOVCLMEAOH-UHFFFAOYSA-N
FDA UNII
15394QZS7A

Idazoxan
A benzodioxane-linked imidazole that has alpha-2 adrenoceptor antagonist activity.
1 2D Structure

Idazoxan

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-(2,3-dihydro-1,4-benzodioxin-3-yl)-4,5-dihydro-1H-imidazole;hydrochloride
2.1.2 InChI
InChI=1S/C11H12N2O2.ClH/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11;/h1-4,10H,5-7H2,(H,12,13);1H
2.1.3 InChI Key
MYUBYOVCLMEAOH-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1CN=C(N1)C2COC3=CC=CC=C3O2.Cl
2.2 Other Identifiers
2.2.1 UNII
15394QZS7A
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Hydrochloride, Idazoxan

2. Idazoxan

3. Rx 781094

4. Rx-781094

5. Rx781094

2.3.2 Depositor-Supplied Synonyms

1. 79944-56-2

2. Idazoxan (hydrochloride)

3. Idazoxan Hcl

4. Rx 781094

5. (+/-)-idazoxan Monohydrochloride

6. Mls000069708

7. Rx-781094

8. Rx 781094 (hydrochloride)

9. 15394qzs7a

10. 2-(2,3-dihydrobenzo[b][1,4]dioxin-2-yl)-4,5-dihydro-1h-imidazole Hydrochloride

11. Smr000058458

12. 79944-56-2 (hcl)

13. 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1h-imidazole Hydrochloride

14. 1h-imidazole, 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-, Monohydrochloride

15. 2-(1,4-benzodioxan-2-yl)-2-imidazoline Hydrochloride

16. Sr-01000000206

17. Unii-15394qzs7a

18. Idazoxan(hydrochloride)

19. Opera_id_847

20. Mls001148081

21. Schembl707367

22. Chembl543467

23. Dtxsid10920189

24. (+/-)-2-[1,4-benzodioxan-2-yl]-2-imidazoline Hydrochloride

25. Hms1570j14

26. Pharmakon1600-01506073

27. Idazoxan Hydrochloride [mi]

28. Ex-a4279

29. Tox21_500652

30. Hy-14561a

31. Nsc759867

32. Akos024458652

33. As-0586

34. Ccg-214002

35. Lp00652

36. Rx-781094a

37. 1h-imidazole, 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-,monohydrochloride

38. Ncgc00094015-01

39. Ncgc00094015-02

40. Ncgc00261337-01

41. 90755-83-2

42. Db-056395

43. Cs-0013117

44. Eu-0100652

45. Ft-0630876

46. I 6138

47. Sr-01000000206-2

48. Sr-01000000206-4

49. Sr-01000000206-6

50. Sr-01000000206-7

51. 2-(1,4-benzodioxan-2-yl)-2-imidazolinehydrochloride

52. Q27251682

53. 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1h-imidazole Hcl

54. 2-(2,3-dihydro-1,4-benzodioxin-3-yl)-4,5-dihydro-1h-imidazole;hydrochloride

55. 2-(2,3-dihydro-1,4-benzodioxin-3-yl)-4,5-dihydro-1h-imidazole;hydron;chloride

56. 1h-imidazole, 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-, Hydrochloride (1:1)

57. 2-(7,10-dioxabicyclo[4.4.0]deca-1,3,5-trien-9-yl)-4,5-dihydro-1h-imidazole Hydrochloride

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 240.68 g/mol
Molecular Formula C11H13ClN2O2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count1
Exact Mass240.0665554 g/mol
Monoisotopic Mass240.0665554 g/mol
Topological Polar Surface Area42.8 Ų
Heavy Atom Count16
Formal Charge0
Complexity267
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Adrenergic alpha-2 Receptor Antagonists

Drugs that bind to and block the activation of ADRENERGIC ALPHA-2 RECEPTORS. (See all compounds classified as Adrenergic alpha-2 Receptor Antagonists.)


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ABOUT THIS PAGE

Idazoxan Manufacturers

A Idazoxan manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Idazoxan, including repackagers and relabelers. The FDA regulates Idazoxan manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Idazoxan API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Idazoxan Suppliers

A Idazoxan supplier is an individual or a company that provides Idazoxan active pharmaceutical ingredient (API) or Idazoxan finished formulations upon request. The Idazoxan suppliers may include Idazoxan API manufacturers, exporters, distributors and traders.

click here to find a list of Idazoxan suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Idazoxan USDMF

A Idazoxan DMF (Drug Master File) is a document detailing the whole manufacturing process of Idazoxan active pharmaceutical ingredient (API) in detail. Different forms of Idazoxan DMFs exist exist since differing nations have different regulations, such as Idazoxan USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Idazoxan DMF submitted to regulatory agencies in the US is known as a USDMF. Idazoxan USDMF includes data on Idazoxan's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Idazoxan USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Idazoxan suppliers with USDMF on PharmaCompass.

Idazoxan GMP

Idazoxan Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Idazoxan GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Idazoxan GMP manufacturer or Idazoxan GMP API supplier for your needs.

Idazoxan CoA

A Idazoxan CoA (Certificate of Analysis) is a formal document that attests to Idazoxan's compliance with Idazoxan specifications and serves as a tool for batch-level quality control.

Idazoxan CoA mostly includes findings from lab analyses of a specific batch. For each Idazoxan CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Idazoxan may be tested according to a variety of international standards, such as European Pharmacopoeia (Idazoxan EP), Idazoxan JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Idazoxan USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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