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Chemistry

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Also known as: 116057-75-1, (e)-1-(2-(4-(1-(4-iodophenyl)-2-phenylbut-1-en-1-yl)phenoxy)ethyl)pyrrolidine, Sb-223030, Cb 7432, Cb-7432, 1-[2-[4-[(e)-1-(4-iodophenyl)-2-phenylbut-1-enyl]phenoxy]ethyl]pyrrolidine
Molecular Formula
C28H30INO
Molecular Weight
523.4  g/mol
InChI Key
JJKOTMDDZAJTGQ-DQSJHHFOSA-N
FDA UNII
456UXE9867

Idoxifene
1 2D Structure

Idoxifene

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
1-[2-[4-[(E)-1-(4-iodophenyl)-2-phenylbut-1-enyl]phenoxy]ethyl]pyrrolidine
2.1.2 InChI
InChI=1S/C28H30INO/c1-2-27(22-8-4-3-5-9-22)28(23-10-14-25(29)15-11-23)24-12-16-26(17-13-24)31-21-20-30-18-6-7-19-30/h3-5,8-17H,2,6-7,18-21H2,1H3/b28-27-
2.1.3 InChI Key
JJKOTMDDZAJTGQ-DQSJHHFOSA-N
2.1.4 Canonical SMILES
CCC(=C(C1=CC=C(C=C1)OCCN2CCCC2)C3=CC=C(C=C3)I)C4=CC=CC=C4
2.1.5 Isomeric SMILES
CC/C(=C(/C1=CC=C(C=C1)OCCN2CCCC2)\C3=CC=C(C=C3)I)/C4=CC=CC=C4
2.2 Other Identifiers
2.2.1 UNII
456UXE9867
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 1-(4-iodophenyl)-1-(4-(2-pyrrolidinoethoxy)phenyl)-2-phenyl-1-butene

2. 4-iodopyrrolidinotamoxifen

3. Pyr-i-tam

4. Pyrrolidino-4-iodotamoxifen

2.3.2 Depositor-Supplied Synonyms

1. 116057-75-1

2. (e)-1-(2-(4-(1-(4-iodophenyl)-2-phenylbut-1-en-1-yl)phenoxy)ethyl)pyrrolidine

3. Sb-223030

4. Cb 7432

5. Cb-7432

6. 1-[2-[4-[(e)-1-(4-iodophenyl)-2-phenylbut-1-enyl]phenoxy]ethyl]pyrrolidine

7. 456uxe9867

8. Iodoxifene

9. Pyrrolidine, 1-(2-(4-(1-(4-iodophenyl)-2-phenyl-1-butenyl)phenoxy)ethyl-, (e)-

10. Pyrrolidino-4-iodotamoxifen

11. Idoxifene [usan:inn:ban]

12. Cis-idoxifene

13. Sb 223030

14. Unii-456uxe9867

15. Idoxifene [inn]

16. Idoxifene [mi]

17. Idoxifene (usan/inn)

18. Idoxifene [usan]

19. Idoxifene [mart.]

20. (e)-1-(2-(4-(1-(4-iodophenyl)-2-phenyl-1-butenyl)phenoxy)ethyl)pyrrolidine

21. Chembl6318

22. Schembl19216

23. Bidd:er0017

24. Dtxsid5043926

25. Chebi:188870

26. Zinc1533058

27. Bdbm50219403

28. Hy-u00178

29. 1-(2-(p-((e)-beta-ethyl-alpha-(p-iodophenyl)styryl)phenoxy)ethyl)pyrrolidine

30. Akos016013971

31. Cs-7245

32. Pyrrolidine, 1-(2-(4-(1-(4-iodophenyl)-2-phenyl-1-butenyl)phenoxy)ethyl)-, (e)-

33. D04496

34. A854422

35. Q5989541

36. 1-(4-iodophenyl)-1-[4-(2-pyrrolizinoethoxy)phenyl]-2-phenyl-1-butene

37. Trans-1-(4-iodophenyl)-1-(4-(2'-pyrrolidinoethoxy)phenyl)-2-phenylbutene

38. (e)-1-(2-(4-(1-(4-iodophenyl)-2-phenylbut-1-enyl)phenoxy)ethyl)pyrrolidine

39. 1-(2-(p-((e)-.beta.-ethyl-.alpha.-(p-iodophenyl)styryl)phenoxy)ethyl)pyrrolidine

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 523.4 g/mol
Molecular Formula C28H30INO
XLogP38.3
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count8
Exact Mass523.13721 g/mol
Monoisotopic Mass523.13721 g/mol
Topological Polar Surface Area12.5 Ų
Heavy Atom Count31
Formal Charge0
Complexity547
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Estrogen Antagonists

Compounds which inhibit or antagonize the action or biosynthesis of estrogenic compounds. (See all compounds classified as Estrogen Antagonists.)


ABOUT THIS PAGE

Idoxifene Manufacturers

A Idoxifene manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Idoxifene, including repackagers and relabelers. The FDA regulates Idoxifene manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Idoxifene API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Idoxifene Suppliers

A Idoxifene supplier is an individual or a company that provides Idoxifene active pharmaceutical ingredient (API) or Idoxifene finished formulations upon request. The Idoxifene suppliers may include Idoxifene API manufacturers, exporters, distributors and traders.

Idoxifene GMP

Idoxifene Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Idoxifene GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Idoxifene GMP manufacturer or Idoxifene GMP API supplier for your needs.

Idoxifene CoA

A Idoxifene CoA (Certificate of Analysis) is a formal document that attests to Idoxifene's compliance with Idoxifene specifications and serves as a tool for batch-level quality control.

Idoxifene CoA mostly includes findings from lab analyses of a specific batch. For each Idoxifene CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Idoxifene may be tested according to a variety of international standards, such as European Pharmacopoeia (Idoxifene EP), Idoxifene JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Idoxifene USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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