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27 API Suppliers, 7 USDMF, 11 CEP/COS, 1 JDMF, 6 EU WC, 4 KDMF, 6 NDC API, 16 Listed Suppliers, $ API Reference Price

27 API Suppliers
7 USDMF
11 CEP/COS
1 JDMF
6 EU WC
4 KDMF
6 NDC API
16 Listed Suppliers
$ API Reference Price

DEVELOPMENTS

4 Drugs in Development

4 Drugs in Development

INTERMEDIATES

1 Intermediates Suppliers

1 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

295 FDF Dossiers, 20 FDA Orange Book, 160 Europe, 25 Canada, 12 Australia, 39 South Africa, 39 Listed Dossiers

295 FDF Dossiers
20 FDA Orange Book
160 Europe
25 Canada
12 Australia
39 South Africa
39 Listed Dossiers

RELATED EXCIPIENT COMPANIES

1 Rochem International Inc, 5 SPI Pharma, 2 Seqens, 3 DKSH, 1 Jai Radhe Sales, 5 Faran Shimi Pharmaceutical, 10 Gangwal Healthcare, 2 Nanjing Well Pharmaceutical, 1 ACG Worldwide, 6 Actylis, 1 Aeon Procare, 5 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 15 BASF, 10 Corel Pharma Chem, 5 DFE Pharma, 1 Finar, 9 Gangwal Chemicals, 5 Ideal Cures Pvt Ltd, 2 Ingredion Pharma Solutions, 35 Kerry, 3 Kima Chemical, 6 Lonza Capsugel, 11 Microlex e.U, 1 Nanjing Bold Chemical, 2 Nomisma Healthcare, 1 Novo Excipients, 1 Pharmatrans-Sanaq, 5 Pluviaendo, 2 Prachin Chemical, 1 Qianhao Chemical (Hebei) Co., Ltd, 1 Qualicaps, 20 Roquette, 13 Seppic, 4 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 10 Sigachi Industries, 2 The Dow Chemical Company, 2 Vasa Pharmachem

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63 Fillers, Diluents & Binders, 45 Coating Systems & Additives, 29 Direct Compression, 26 Controlled & Modified Release, 21 Thickeners and Stabilizers, 17 Granulation, 17 Solubilizers, 15 Lubricants & Glidants, 15 Co-Processed Excipients, 12 Taste Masking, 11 Topical, 10 Film Formers & Plasticizers, 10 Disintegrants & Superdisintegrants, 8 Parenteral, 7 Chewable & Orodispersible Aids, 7 Emulsifying Agents, 5 Empty Capsules, 5 API Stability Enhancers, 4 Vegetarian Capsules, 4 Coloring Agents, 3 Surfactant & Foaming Agents, 3 Rheology Modifiers

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1 US Medicaid Prescriptions, 160 Finished Drug Prices

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1 US Medicaid Prescriptions
160 Finished Drug Prices

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16 APIs, 5 FDF Dossiers

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16 APIs
5 FDF Dossiers

REF. STANDARDS & IMPURITIES

3 EDQM , 3 USP , 4 JP , 13 Others

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3 EDQM
3 USP
4 JP
13 Others

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1 BioAnalytical Methods, 1 Analytical Methods

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Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

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EU WC

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NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 783

MARKET PLACE

API

FDF

1INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

295

FDF Dossiers

FDA Orange Book

160

Europe

Canada

Australia

South Africa

Listed Dossiers

4DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

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US Patents

US Exclusivities

Health Canada Patents

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GLOBAL SALES INFORMATION

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Annual Reports (USD Million)

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209 RELATED EXCIPIENT COMPANIES

337EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: 26807-65-8, Noranat, Veroxil, Tertensif, Lozol, Indaflex

Molecular Formula

C₁₆H₁₆ClN₃O₃S

Molecular Weight

365.8 g/mol

InChI Key

NDDAHWYSQHTHNT-UHFFFAOYSA-N

FDA UNII

F089I0511L

A benzamide-sulfonamide-indole derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS.

Indapamide is a Thiazide-like Diuretic. The physiologic effect of indapamide is by means of Increased Diuresis.

1 2D Structure

Indapamide

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

4-chloro-N-(2-methyl-2,3-dihydroindol-1-yl)-3-sulfamoylbenzamide

2.1.2 InChI

InChI=1S/C16H16ClN3O3S/c1-10-8-11-4-2-3-5-14(11)20(10)19-16(21)12-6-7-13(17)15(9-12)24(18,22)23/h2-7,9-10H,8H2,1H3,(H,19,21)(H2,18,22,23)

2.1.3 InChI Key

NDDAHWYSQHTHNT-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CC1CC2=CC=CC=C2N1NC(=O)C3=CC(=C(C=C3)Cl)S(=O)(=O)N

2.2 Other Identifiers

2.2.1 UNII

F089I0511L

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Metindamide

2. S 1520

3. S-1520

4. S1520

5. Se 1520

6. Se-1520

7. Se1520

2.3.2 Depositor-Supplied Synonyms

1. 26807-65-8

2. Noranat

3. Veroxil

4. Tertensif

5. Lozol

6. Indaflex

7. Arifon

8. Fludex

9. Indamol

10. Bajaten

11. Ipamix

12. Tandix

13. Natrilix

14. Damide

15. Pressurai

16. Indapamida

17. Indapamidum

18. Natrix

19. Indapamidum [inn-latin]

20. Indapamida [inn-spanish]

21. Se-1520

22. Flupamid

23. Indamide

24. 1-(4-chloro-3-sulfamoylbenzamido)-2-methylindoline

25. Fludin

26. Lorvas

27. 4-chloro-n-(2-methyl-2,3-dihydroindol-1-yl)-3-sulfamoylbenzamide

28. S-1520

29. Benzamide, 3-(aminosulfonyl)-4-chloro-n-(2,3-dihydro-2-methyl-1h-indol-1-yl)-

30. 4-chloro-n-(2-methyl-1-indolinyl)-3-sulfamoylbenzamide

31. Indapamide (lozol)

32. Flubest

33. 4-chloro-n-(2-methyl-2,3-dihydro-1h-indol-1-yl)-3-sulfamoylbenzamide

34. Metindamide

35. Cormil

36. Nsc-757075

37. N-(4-chloro-3-sulfamoylbenzamido)-2-methylindoline

38. Mls000028554

39. Chebi:5893

40. 26807-65-8(free Base)

41. Kyd-041

42. Benzamide, 4-chloro-n-(2-methyl-1-indolinyl)-3-sulfamoyl-

43. F089i0511l

44. Ncgc00018172-03

45. Smr000058829

46. 4-chloro-n-(2-methylindolin-1-yl)-3-sulfamoylbenzamide

47. Dsstox_cid_24633

48. Dsstox_rid_80366

49. Dsstox_gsid_44633

50. Se 1520

51. Rhc 2555

52. Usv 2555

53. Natrix (tn)

54. Lozol (tn)

55. Sr-01000003079

56. Einecs 248-012-7

57. Mfcd00079375

58. Brn 1604026

59. Unii-f089i0511l

60. Hypen Sr

61. 3-(aminosulfonyl)-4-chloro-n-(2,3-dihydro-2-methyl-1h-indol-1-yl)benzamide

62. Indapamide [usan:usp:inn:ban:jan]

63. Spectrum_000917

64. Indapamide [mi]

65. Opera_id_110

66. Indapamide [inn]

67. Indapamide [jan]

68. Prestwick3_000220

69. Spectrum2_000980

70. Spectrum3_000467

71. Spectrum4_000017

72. Spectrum5_000866

73. Indapamide [usan]

74. S1520

75. Indapamide [vandf]

76. Chembl406

77. Indapamide (jp17/usp)

78. Indapamide [mart.]

79. Indapamide [usp-rs]

80. Indapamide [who-dd]

81. Schembl41303

82. Bspbio_000239

83. Bspbio_002174

84. Kbiogr_000393

85. Kbioss_001397

86. 5-20-06-00348 (beilstein Handbook Reference)

87. Mls001148152

88. Mls002222229

89. Mls006011900

90. Divk1c_000508

91. Spectrum1500349

92. Spbio_001019

93. Bpbio1_000263

94. Gtpl7203

95. Dtxsid7044633

96. Indapamide [ep Impurity]

97. Indapamide [orange Book]

98. Bdbm25901

99. Hms501j10

100. Kbio1_000508

101. Kbio2_001397

102. Kbio2_003965

103. Kbio2_006533

104. Kbio3_001394

105. Indapamide [ep Monograph]

106. Ninds_000508

107. Hms1920f19

108. Hms2090m16

109. Hms2091n07

110. Hms2095l21

111. Hms2231g13

112. Hms3259c14

113. Hms3369j20

114. Hms3655e06

115. Hms3712l21

116. Hms3748k05

117. Indapamide [usp Monograph]

118. Pharmakon1600-01500349

119. Indapamide 1.0 Mg/ml In Methanol

120. Amy31945

121. Bcp04140

122. Hy-b0259

123. Tox21_110775

124. Tox21_113182

125. Tox21_302687

126. Ccg-40198

127. Nsc757075

128. S1730

129. Stl257105

130. Stl455045

131. 3-(aminosulfonyl)-4-chloro-n-(2-methyl-2,3-dihydro-1h-indol-1-yl)benzamide

132. Akos015888148

133. Tox21_110775_1

134. Ab03037

135. Ac-2073

136. Db00808

137. Ks-5219

138. Nc00568

139. Nsc 757075

140. Benzamide, 3-(aminosulfonyl)-4-chloro-n-(2,3-dihydro-2-methyl-1h-indol-l-yl)-

141. Idi1_000508

142. Ncgc00018172-02

143. Ncgc00018172-04

144. Ncgc00018172-06

145. Ncgc00018172-08

146. Ncgc00018172-09

147. Ncgc00089727-02

148. Ncgc00089727-03

149. Ncgc00256884-01

150. Sbi-0051415.p003

151. Db-047020

152. Ab00052021

153. I0730

154. Sw198686-2

155. A23574

156. D00345

157. Ab00052021-14

158. Ab00052021-15

159. Ab00052021_16

160. Ab00052021_17

161. 807i658

162. Indapamide, Analytical Standard, For Drug Analysis

163. J-016554

164. Q1078392

165. Sr-01000003079-2

166. Sr-01000003079-3

167. Brd-a95869247-001-04-6

168. Brd-a95869247-001-14-5

169. Z2786158257

170. Indapamide, British Pharmacopoeia (bp) Reference Standard

171. Indapamide, European Pharmacopoeia (ep) Reference Standard

172. Indapamide, United States Pharmacopeia (usp) Reference Standard

173. 3-aminosulfonyl-4-chloro-n-(2,3-dihydro-2-methyl-1h-indol-1-yl)benzamide

174. 4-chloro-3-aminosulphonyl-n-(2,3-dihydro2-methyl-1h-indol-1-yl)benzamide

175. Indapamide, Pharmaceutical Secondary Standard; Certified Reference Material

176. 3-(aminosulphonyl)-4-chloro-n-(2-methyl-2,3-dihydro-1h-indol-1--yl)benzamide

177. 3-(aminosulphonyl)-4-chloro-n-(2-methyl-2,3-dihydro-1h-indol-1-yl)benzamide

178. 4-chloro-n-(2-methyl-2,3-dihydro-1h-indol-1-yl)-3-sulfamoylbenzenecarboximidic Acid

2.4 Create Date

2005-03-25

3 Chemical and Physical Properties

Molecular Formula	C₁₆H₁₆ClN₃O₃S
Molecular Weight	365.8 g/mol
XLogP3	2.9
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	3
Exact Mass	365.0600902 g/mol
Monoisotopic Mass	365.0600902 g/mol
Topological Polar Surface Area	101 Å²
Heavy Atom Count	24
Formal Charge	0
Complexity	580
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Drug and Medication Information

4.1 Drug Information

1 of 2
Drug Name	Indapamide
PubMed Health	Indapamide (By mouth)
Drug Classes	Cardiovascular Agent
Drug Label	Indapamide is an oral antihypertensive/diuretic. Its molecule contains both a polar sulfamoyl chlorobenzamide moiety and a lipid-soluble methylindoline moiety. It differs chemically from the thiazides in that it does not possess the thiazide ring sys...
Active Ingredient	Indapamide
Dosage Form	Tablet
Route	Oral
Strength	2.5mg; 1.25mg
Market Status	Prescription
Company	Mylan Pharms; Ivax Sub Teva Pharms; Actavis Elizabeth; Mylan

2 of 2
Drug Name	Indapamide
PubMed Health	Indapamide (By mouth)
Drug Classes	Cardiovascular Agent
Drug Label	Indapamide is an oral antihypertensive/diuretic. Its molecule contains both a polar sulfamoyl chlorobenzamide moiety and a lipid-soluble methylindoline moiety. It differs chemically from the thiazides in that it does not possess the thiazide ring sys...
Active Ingredient	Indapamide
Dosage Form	Tablet
Route	Oral
Strength	2.5mg; 1.25mg
Market Status	Prescription
Company	Mylan Pharms; Ivax Sub Teva Pharms; Actavis Elizabeth; Mylan

4.2 Drug Indication

Indapamide is a diuretic indicated for use as monotherapy or in combination with other blood pressure-lowering agents to treat hypertension. It may also be used to treat fluid and salt retention associated with congestive heart failure.

FDA Label

5 Pharmacology and Biochemistry

5.1 Pharmacology

Classified as a sulfonamide diuretic, indapamide is an effective antihypertensive agent and by extension, has shown efficacy in the prevention of target organ damage. Administration of indapamide produces water and electrolyte loss, with higher doses associated with increased diuresis. Severe and clinically significant electrolyte disturbances may occur with indapamide use - for example, hypokalemia resulting from renal potassium loss may lead to QTc prolongation. Further electrolyte imbalances may occur due to renal excretion of sodium, chloride, and magnesium. Other indapamide induced changes include increases in plasma renin and aldosterone, and reduced calcium excretion in the urine. In many studies investigating the effects of indapamide in both non-diabetic and diabetic hypertensive patients, glucose tolerance was not significantly altered. However, additional studies are necessary to assess the long term metabolic impacts of indapamide, since thiazide related impaired glucose tolerance can take several years to develop in non-diabetic patients.

5.2 MeSH Pharmacological Classification

Diuretics

Agents that promote the excretion of urine through their effects on kidney function. (See all compounds classified as Diuretics.)

Antihypertensive Agents

Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS. (See all compounds classified as Antihypertensive Agents.)

Sodium Chloride Symporter Inhibitors

Agents that inhibit SODIUM CHLORIDE SYMPORTERS. They act as DIURETICS. Excess use is associated with HYPOKALEMIA. (See all compounds classified as Sodium Chloride Symporter Inhibitors.)

5.3 FDA Pharmacological Classification

5.3.1 Active Moiety

INDAPAMIDE

5.3.2 FDA UNII

F089I0511L

5.3.3 Pharmacological Classes

Thiazide-like Diuretic [EPC]; Increased Diuresis [PE]

5.4 ATC Code

C03BA11

S76 | LUXPHARMA | Pharmaceuticals Marketed in Luxembourg | Pharmaceuticals marketed in Luxembourg, as published by d'Gesondheetskeess (CNS, la caisse nationale de sante, www.cns.lu), mapped by name to structures using CompTox by R. Singh et al. (in prep.). List downloaded from https://cns.public.lu/en/legislations/textes-coordonnes/liste-med-comm.html. Dataset DOI:10.5281/zenodo.4587355

C - Cardiovascular system

C03 - Diuretics

C03B - Low-ceiling diuretics, excl. thiazides

C03BA - Sulfonamides, plain

C03BA11 - Indapamide

5.5 Absorption, Distribution and Excretion

Absorption

The bioavailability of indapamide is virtually complete after an oral dose and is unaffected by food or antacids. Indapamide is highly lipid-soluble due to its indoline moiety - a characteristic that likely explains why indapamides renal clearance makes up less than 10% of its total systemic clearance. The Tmax occurs approximately 2.3 hours after oral administration. The Cmax and AUC_0-24 values are 263 ng/mL and 2.95 ug/hr/mL, respectively.

Route of Elimination

An estimated 60-70% of indapamide is eliminated in the urine, while 16-23% is eliminated in the feces.

Volume of Distribution

Some sources report an apparent volume of distribution of 25 L for indapamide, while others report a value of approximately 60 L.

Clearance

Indapamide's renal and hepatic clearance values are reported to be 1.71 mL/min and 20-23.4 mL/min, respectively.

5.6 Metabolism/Metabolites

As a result of extensive metabolism in the liver, the majority of indapamide excreted is metabolized, with only 7% remaining unchanged. In humans, as many as 19 distinct indapamide metabolites may be produced, although not all have been identified. There are several metabolic routes through which indapamide may be metabolized, and CYP3A4 is the main enzyme involved in the corresponding hydroxylation, carboxylation, and dehydrogenation reactions. Indapamide can undergo dehydrogenation to form M5, then oxidation to form M4, then further hydroxylation at the indole moiety to form M2. These reactions are facilitated by CYP3A4. Another route of metabolism occurs when indapamide is first hydroxylated to M1 by CYP3A4. M1 then undergoes dehydrogenation to form M3 and is further oxidized to form M2. Hydroxylation of indapamides indole moiety is thought to form the major metabolite (M1), which is less pharmacologically active compared to its parent compound according to animal studies. Indapamide may also undergo epoxidation via CYP3A4 to form a reactive epoxide intermediate. The unstable epoxide intermediate may then undergo dihydroxylation via microsomal epoxide hydrolase to form M6, or glutathione conjugation to form M7.

5.7 Biological Half-Life

Indapamide is characterized by biphasic elimination. In healthy subjects, indapamide's elimination half-life can range from 13.9 to 18 hours. The long half-life is conducive to once-daily dosing.

5.8 Mechanism of Action

Indapamide acts on the nephron, specifically at the proximal segment of the distal convoluted tubule where it inhibits the Na+/Cl- cotransporter, leading to reduced sodium reabsorption. As a result, sodium and water are retained in the lumen of the nephron for urinary excretion. The effects that follow include reduced plasma volume, reduced venous return, lower cardiac output, and ultimately decreased blood pressure. Interestingly, it is likely that thiazide-like diuretics such as indapamide have additional blood pressure lowering mechanisms that are unrelated to diuresis. This is exemplified by the observation that the antihypertensive effects of thiazides are sustained 4-6 weeks after initiation of therapy, despite recovering plasma and extracellular fluid volumes. Some studies have suggested that indapamide may decrease responsiveness to pressor agents while others have suggested it can decrease peripheral resistance. Although it is clear that diuresis contributes to the antihypertensive effects of indapamide, further studies are needed to investigate the medications ability to decrease peripheral vascular resistance and relax vascular smooth muscle.

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Axplora

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Indapamide

About the Company : Axplora, created from the merger of Farmabios, Novasep & PharmaZell, is a leading API manufacturing partner to the world’s leading pharma & biotech companies, delivering top-qual...

Axplora, created from the merger of Farmabios, Novasep & PharmaZell, is a leading API manufacturing partner to the world’s leading pharma & biotech companies, delivering top-quality APIs on time & at scale, to the highest industry standards. It is dedicated to helping pharma companies make critical medicines safely to benefit patients. Leveraging our combined expertise & manufacturing capabilities across 9 industrial sites in the EU & India & an R&D facility in the USA, it offers CDMO services for small molecule APIs & biopharmaceuticals to innovators as well as APIs that address lifestyle-induced respiratory, inflammatory & liver diseases.

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About the Company : LGM Pharma is a global leader in sourcing hard-to-find APIs and intermediates for the pharmaceutical and biotech industries. LGM is also a full service CDMO providing formulation, ...

LGM Pharma is a global leader in sourcing hard-to-find APIs and intermediates for the pharmaceutical and biotech industries. LGM is also a full service CDMO providing formulation, analytical method development and testing, and commercial manufacturing. LGM Pharma offers custom API synthesis, analytical development, and regulatory services. With a network of over 300 accredited CGMP manufacturing partners, LGM provides unparalleled supply chain security. And, with over 100,000 square feet of FDA-inspected cGMP manufacturing and warehouse capacity, LGM Pharma provides a one-stop solution for solid dose, powder, semi-solid and liquid drugs.

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Indapamide

About the Company : Octavius Pharma is a global leader in Directly Compressible Granules with over 40 years of experience in Formulation development, manufacturing and commercialization. It offers a w...

Octavius Pharma is a global leader in Directly Compressible Granules with over 40 years of experience in Formulation development, manufacturing and commercialization. It offers a wide range of products such as tablets, capsules, syrups and ointments. Its portfolio includes finished dosage formulations, herbal/food supplements and APIs. It exports bulk drugs, finished formulations and APIs, while maintaining quality in compliance with WHO GMP norms. With an experienced team, Octavius Pharma provides consulting services for formulation development and marketing. Octavius exports to LATAM, Middle East, African, Asian and CIS countries.

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API Reference Price

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ROAD"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1725906600,"product":"INDAPAMIDE","address":"102,TITAN HOUSE,60 FEET RD,","city":"MUMBAI, MAHARASHTRA","supplier":"NEXCHEM PHARMACEUTICAL CO, LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"TITAN LABORATORIES","customerCountry":"INDIA","quantity":"50.00","actualQuantity":"50","unit":"KGS","unitRateFc":"450","totalValueFC":"22795","currency":"USD","unitRateINR":"38205","date":"10-Sep-2024","totalValueINR":"1910250","totalValueInUsd":"22795","indian_port":"Bombay Air","hs_no":"29359090","bill_no":"5528991","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"NO 21 TANGXI ROAD ,SUZHOU NEW DISTR ICT 215151 P R CHINA Suzhou New Dis trict, , China China China","customerAddress":"102,TITAN HOUSE,60 FEET RD,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1728412200,"product":"INDAPAMIDE","address":"564\/A\/22, ROAD NO.92","city":"HYDERABAD,ANDHRA PRADESH","supplier":"RECIPHARM AB","supplierCountry":"ITALY","foreign_port":"MILAN - MALPENSA","customer":"VIATRIS","customerCountry":"INDIA","quantity":"10.00","actualQuantity":"10","unit":"KGS","unitRateFc":"1850","totalValueFC":"20750.9","currency":"EUR","unitRateINR":"174362.5","date":"09-Oct-2024","totalValueINR":"1743625","totalValueInUsd":"20750.9","indian_port":"Bombay Air","hs_no":"29359090","bill_no":"6031628","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"MILAN - MALPENSA","supplierAddress":"Sede legale, amministrativa e sito produttivo Strada Statale dei Giovi , 131 20037 Paderno Dugnano (MI) - Italy","customerAddress":"564\/A\/22, ROAD NO.92"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1729621800,"product":"INDAPAMIDE MICRONIZED","address":"PIRAMAL ANANTA, PIRAMAL AGASTYA PARK","city":"KURLA, MUMBAI","supplier":"CHEMO","supplierCountry":"SPAIN","foreign_port":"MADRID","customer":"PIRAMAL PHARMA SOLUTIONS","customerCountry":"INDIA","quantity":"7.57","actualQuantity":"7.57","unit":"KGS","unitRateFc":"2600","totalValueFC":"19898.3","currency":"USD","unitRateINR":"220870","date":"23-Oct-2024","totalValueINR":"1671985.9","totalValueInUsd":"19898.3","indian_port":"Bombay Air","hs_no":"29359090","bill_no":"6291611","productDescription":"API","marketType":"REGULATED MARKET","country":"SPAIN","selfForZScoreResived":"Micronized","supplierPort":"MADRID","supplierAddress":"LUGANO BRANCH VIA.F.PELLI 17 , P.O. BOX 6901 LUGANO SWITZERLAND , , Swi tzerland Switzerland","customerAddress":"PIRAMAL ANANTA, PIRAMAL AGASTYA PARK"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1729621800,"product":"INDAPAMIDE MICRONIZED","address":"PIRAMAL ANANTA, PIRAMAL AGASTYA PARK","city":"KURLA, MUMBAI","supplier":"CHEMO","supplierCountry":"SPAIN","foreign_port":"MADRID","customer":"PIRAMAL PHARMA SOLUTIONS","customerCountry":"INDIA","quantity":"11.47","actualQuantity":"11.47","unit":"KGS","unitRateFc":"2600","totalValueFC":"30149.7","currency":"USD","unitRateINR":"220870","date":"23-Oct-2024","totalValueINR":"2533378.9","totalValueInUsd":"30149.7","indian_port":"Bombay Air","hs_no":"29359090","bill_no":"6291611","productDescription":"API","marketType":"REGULATED MARKET","country":"SPAIN","selfForZScoreResived":"Micronized","supplierPort":"MADRID","supplierAddress":"LUGANO BRANCH VIA.F.PELLI 17 , P.O. BOX 6901 LUGANO SWITZERLAND , , Swi tzerland Switzerland","customerAddress":"PIRAMAL ANANTA, PIRAMAL AGASTYA PARK"}]

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country	Total Quantity (KGS)	Average Price (USD/KGS)	Number of Transactions

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INTERMEDIATES SUPPLIERS

01

Actis Generics Pvt Ltd

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ACTIVE PHARMA INGREDIENTS

27 API Suppliers

7 USDMF

11 CEP/COS

1 JDMF

6 EU WC

4 KDMF

6 NDC API

16 Listed Suppliers

$ API Reference Price

DEVELOPMENTS

4 Drugs in Development

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FINISHED DOSAGE FORMULATIONS

295 FDF Dossiers

20 FDA Orange Book

160 Europe

25 Canada

12 Australia

39 South Africa

39 Listed Dossiers

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3 DKSH

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10 Gangwal Healthcare

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1 ACG Worldwide

6 Actylis

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5 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd

15 BASF

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5 DFE Pharma

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11 Microlex e.U

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1 Qualicaps

20 Roquette

13 Seppic

4 Shanghai Shenmei Pharmaceutical Technology Co., Ltd

10 Sigachi Industries

2 The Dow Chemical Company

2 Vasa Pharmachem

EXCIPIENTS BY APPLICATIONS

63 Fillers, Diluents & Binders

45 Coating Systems & Additives

29 Direct Compression

26 Controlled & Modified Release

21 Thickeners and Stabilizers

17 Granulation

17 Solubilizers

15 Lubricants & Glidants

15 Co-Processed Excipients

12 Taste Masking

11 Topical

10 Film Formers & Plasticizers

10 Disintegrants & Superdisintegrants

8 Parenteral