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    Chemistry

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    Also known as: Isoprinosine, 36703-88-5, Inosiplex, Delimmun, Methisoprinol, Imunovir
    Molecular Formula
    C52H78N10O17
    Molecular Weight
    1115.2  g/mol
    InChI Key
    YLDCUKJMEKGGFI-QCSRICIXSA-N
    FDA UNII
    W1SO0V223F
    Inosine Pranobex
    An alkylamino-alcohol complex of inosine used in the treatment of a variety of viral infections. Unlike other antiviral agents, it acts by modifying or stimulating cell-mediated immune processes rather than acting on the virus directly.
    1 2D Structure

    Inosine Pranobex

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    4-acetamidobenzoic acid;9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one;1-(dimethylamino)propan-2-ol
    2.1.2 InChI
    InChI=1S/C10H12N4O5.3C9H9NO3.3C5H13NO/c15-1-4-6(16)7(17)10(19-4)14-3-13-5-8(14)11-2-12-9(5)18;3*1-6(11)10-8-4-2-7(3-5-8)9(12)13;3*1-5(7)4-6(2)3/h2-4,6-7,10,15-17H,1H2,(H,11,12,18);3*2-5H,1H3,(H,10,11)(H,12,13);3*5,7H,4H2,1-3H3/t4-,6-,7-,10-;;;;;;/m1....../s1
    2.1.3 InChI Key
    YLDCUKJMEKGGFI-QCSRICIXSA-N
    2.1.4 Canonical SMILES
    CC(CN(C)C)O.CC(CN(C)C)O.CC(CN(C)C)O.CC(=O)NC1=CC=C(C=C1)C(=O)O.CC(=O)NC1=CC=C(C=C1)C(=O)O.CC(=O)NC1=CC=C(C=C1)C(=O)O.C1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)CO)O)O
    2.1.5 Isomeric SMILES
    CC(CN(C)C)O.CC(CN(C)C)O.CC(CN(C)C)O.CC(=O)NC1=CC=C(C=C1)C(=O)O.CC(=O)NC1=CC=C(C=C1)C(=O)O.CC(=O)NC1=CC=C(C=C1)C(=O)O.C1=NC2=C(C(=O)N1)N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O
    2.2 Other Identifiers
    2.2.1 UNII
    W1SO0V223F
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Imunovir

    2. Inosiplex

    3. Isoprinosin

    4. Isoprinosine

    5. Methisoprinol

    6. Methysoprinol

    7. Metisoprinol

    8. Npt 10381

    9. Npt-10381

    10. Npt10381

    11. Pranobex, Inosine

    2.3.2 Depositor-Supplied Synonyms

    1. Isoprinosine

    2. 36703-88-5

    3. Inosiplex

    4. Delimmun

    5. Methisoprinol

    6. Imunovir

    7. Isoviral

    8. Viruxan

    9. Isoprinosin

    10. Isoprinosina

    11. Aviral

    12. Inosine Acedobene Dimepranol

    13. Imunoviral

    14. Modimmunal

    15. Immunovir

    16. Pranosina

    17. Pranosine

    18. Np 113

    19. Npt-10381

    20. W1so0v223f

    21. Np-113

    22. Inosine Pranobex (jan)

    23. Inosine-2-hydroxypropyldimethylammonium 4-acetamidobenzoate (1:3)

    24. Inosine Pranobex [jan]

    25. 4-acetamidobenzoic Acid,9-((2r,3r,4s,5r)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3h-purin-6(9h)-one,1-(dimethylamino)propan-2-ol (3:1:3)

    26. 4-acetamidobenzoic Acid;9-[(2r,3r,4s,5r)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3h-purin-6-one;1-(dimethylamino)propan-2-ol

    27. Inosine Pranobex [ban:jan]

    28. Einecs 253-162-1

    29. Ntp 10381

    30. Unii-w1so0v223f

    31. Groprinosin

    32. Isoprinosine (tn)

    33. Inosine, Compd. With 1-(dimethylamino)-2-propanol 4-(acetylamino)benzoate (salt) (1:3)

    34. Inosine, Compound With (2-hydroxypropyl)dimethylammonium P-acetamidobenzoate (1:3)

    35. Inosine Pranobex [mi]

    36. Chembl3833327

    37. Inosine Pranobex [mart.]

    38. Inosine Pranobex [who-dd]

    39. Dtxsid401021342

    40. Iad

    41. Mfcd05662374

    42. S5016

    43. Akos025312516

    44. Akos030228417

    45. Ccg-270642

    46. As-12319

    47. Hy-107801

    48. Cs-0030676

    49. I1037

    50. C74892

    51. D01995

    52. 703i885

    53. A874300

    54. Q3130053

    55. P-acetamidobenzoic Salt Of N,n-dimethylamino-2-propanol & Inosine (3:1)

    56. Inosine & 1-(dimethylamino)-2-propanol & 4-(acetylamino)benzoate (salt) (1:3:3)

    57. 4-acetamidobenzoic Acid; 9-[(2r,3r,4s,5r)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1h-purin-6-one; 1-(dimethylamino)propan-2-ol

    58. 4-acetamidobenzoic Acid;9-[(2r,3r,4s,5r)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1h-purin-6-one;1-(dimethylamino)propan-2-ol

    2.4 Create Date
    2019-01-15
    3 Chemical and Physical Properties
    Molecular Weight 1115.2 g/mol
    Molecular Formula C52H78N10O17
    Hydrogen Bond Donor Count13
    Hydrogen Bond Acceptor Count22
    Rotatable Bond Count14
    Exact Mass1114.55464106 g/mol
    Monoisotopic Mass1114.55464106 g/mol
    Topological Polar Surface Area399 Ų
    Heavy Atom Count79
    Formal Charge0
    Complexity658
    Isotope Atom Count0
    Defined Atom Stereocenter Count4
    Undefined Atom Stereocenter Count3
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count7
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Adjuvants, Immunologic

    Substances that augment, stimulate, activate, potentiate, or modulate the immune response at either the cellular or humoral level. The classical agents (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contain bacterial antigens. Some are endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Their mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy of many biological response modifiers is related to their antigen-specific immunoadjuvanticity. (See all compounds classified as Adjuvants, Immunologic.)

    Antiviral Agents

    Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly. (See all compounds classified as Antiviral Agents.)

    4.2 ATC Code

    J - Antiinfectives for systemic use

    J05 - Antivirals for systemic use

    J05A - Direct acting antivirals

    J05AX - Other antivirals

    J05AX05 - Inosine pranobex

    API SUPPLIERS

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    ICE Pharma

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    Medilux Laboratories

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    API Reference Price

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    [{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1707849000,"product":"(INOSINE PRANOBEX) METHISOPRINOL (INTERMEDIATE PRODUCTS)","address":"B-101, VASUNDHRA 5, POONAM SAGAR,","city":"ABOVE KIDZEE SCHOOL THANE MS","supplier":"S AND Y BIOCHEM CO., LTD","supplierCountry":"CHINA","foreign_port":"BEIJING","customer":"ORGANICS","customerCountry":"INDIA","quantity":"600.00","actualQuantity":"600","unit":"KGS","unitRateFc":"14.2","totalValueFC":"8600","currency":"USD","unitRateINR":"1189.3","date":"14-Feb-2024","totalValueINR":"713575.02","totalValueInUsd":"8600","indian_port":"Delhi Air","hs_no":"29349990","bill_no":"2142266","productDescription":"Intermediate","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BEIJING","supplierAddress":"NO.1501,UNIT 2,SHUHE CHENGBANG CITYSHUHE SOUTH STREET,LANSHAN DISTRICT LINYI CITY PROVINCE LINYI CITY, S CHINA","customerAddress":"B-101, VASUNDHRA 5, POONAM SAGAR,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1713897000,"product":"(INOSINE PRANOBEX) METHISOPRINOL (INTERMEDIATE PRODUCTS)","address":"B-101, VASUNDHRA 5, POONAM SAGAR,","city":"ABOVE KIDZEE SCHOOL THANE MS","supplier":"S AND Y BIOCHEM CO., LTD","supplierCountry":"CHINA","foreign_port":"BEIJING","customer":"ORGANICS","customerCountry":"INDIA","quantity":"1000.00","actualQuantity":"1000","unit":"KGS","unitRateFc":"17.5","totalValueFC":"17687.1","currency":"USD","unitRateINR":"1477","date":"24-Apr-2024","totalValueINR":"1477000","totalValueInUsd":"17687.1","indian_port":"Delhi Air","hs_no":"29349990","bill_no":"3186817","productDescription":"Intermediate","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BEIJING","supplierAddress":"NO.1501,UNIT 2,SHUHE CHENGBANG CITYSHUHE SOUTH STREET,LANSHAN DISTRICT LINYI CITY PROVINCE LINYI CITY, S CHINA","customerAddress":"B-101, VASUNDHRA 5, POONAM SAGAR,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1717439400,"product":"(INOSINE PRANOBEX) METHISOPRINOL (INTERMEDIATE PRODUCTS)","address":"B-101, VASUNDHRA 5, POONAM SAGAR,","city":"ABOVE KIDZEE SCHOOL THANE MS","supplier":"WILL BIOPHARMA PVT LIMITED","supplierCountry":"CHINA","foreign_port":"BEIJING","customer":"ORGANICS","customerCountry":"INDIA","quantity":"500.00","actualQuantity":"500","unit":"KGS","unitRateFc":"17.5","totalValueFC":"8841.3","currency":"USD","unitRateINR":"1476.1","date":"04-Jun-2024","totalValueINR":"738062.5","totalValueInUsd":"8841.3","indian_port":"Delhi Air","hs_no":"29349990","bill_no":"3828077","productDescription":"Intermediate","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BEIJING","supplierAddress":"UNIT 1406B 14\/F THE BELGIANBANK BLDG NOS 721-725 NATHANRD KIN NATHANRDKIN, , HONG KONG HONG KONG","customerAddress":"B-101, VASUNDHRA 5, POONAM SAGAR,"}]
    14-Feb-2024
    04-Jun-2024
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    ABOUT THIS PAGE

    Inosine Pranobex Manufacturers

    A Inosine Pranobex manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Inosine Pranobex, including repackagers and relabelers. The FDA regulates Inosine Pranobex manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Inosine Pranobex API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Inosine Pranobex manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Inosine Pranobex Suppliers

    A Inosine Pranobex supplier is an individual or a company that provides Inosine Pranobex active pharmaceutical ingredient (API) or Inosine Pranobex finished formulations upon request. The Inosine Pranobex suppliers may include Inosine Pranobex API manufacturers, exporters, distributors and traders.

    click here to find a list of Inosine Pranobex suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Inosine Pranobex GMP

    Inosine Pranobex Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Inosine Pranobex GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Inosine Pranobex GMP manufacturer or Inosine Pranobex GMP API supplier for your needs.

    Inosine Pranobex CoA

    A Inosine Pranobex CoA (Certificate of Analysis) is a formal document that attests to Inosine Pranobex's compliance with Inosine Pranobex specifications and serves as a tool for batch-level quality control.

    Inosine Pranobex CoA mostly includes findings from lab analyses of a specific batch. For each Inosine Pranobex CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Inosine Pranobex may be tested according to a variety of international standards, such as European Pharmacopoeia (Inosine Pranobex EP), Inosine Pranobex JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Inosine Pranobex USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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